Vitelline Duct

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Dronen, Norman O. - One of the best experts on this subject based on the ideXlab platform.

Atef Asnacios - One of the best experts on this subject based on the ideXlab platform.

  • mechanical tension drives elongational growth of the embryonic gut
    Scientific Reports, 2018
    Co-Authors: Nicolas R. Chevalier, Tinkemarie De Witte, Annemiek J M Cornelissen, Sylvie Dufour, Veronique Prouxgillardeaux, Atef Asnacios
    Abstract:

    During embryonic development, most organs are in a state of mechanical compression because they grow in a confined and limited amount of space within the embryo’s body; the early gut is an exception because it physiologically herniates out of the coelom. We demonstrate here that physiological hernia is caused by a tensile force transmitted by the Vitelline Duct on the early gut loop at its attachment point at the umbilicus. We quantify this tensile force and show that applying tension for 48 h induces stress-dependent elongational growth of the embryonic gut in culture, with an average 90% length increase (max: 200%), 65% volume increase (max: 160%), 50% dry mass increase (max: 100%), and 165% cell number increase (max: 300%); this mechanical cue is required for organ growth as guts not subject to tension do not grow. We demonstrate that growth results from increased cell proliferation when tension is applied. These results outline the essential role played by mechanical forces in shaping and driving the proliferation of embryonic organs.

Sylvie Dufour - One of the best experts on this subject based on the ideXlab platform.

  • mechanical tension drives elongational growth of the embryonic gut
    Scientific Reports, 2018
    Co-Authors: Nicolas R. Chevalier, Tinkemarie De Witte, Annemiek J M Cornelissen, Sylvie Dufour, Veronique Prouxgillardeaux, Atef Asnacios
    Abstract:

    During embryonic development, most organs are in a state of mechanical compression because they grow in a confined and limited amount of space within the embryo’s body; the early gut is an exception because it physiologically herniates out of the coelom. We demonstrate here that physiological hernia is caused by a tensile force transmitted by the Vitelline Duct on the early gut loop at its attachment point at the umbilicus. We quantify this tensile force and show that applying tension for 48 h induces stress-dependent elongational growth of the embryonic gut in culture, with an average 90% length increase (max: 200%), 65% volume increase (max: 160%), 50% dry mass increase (max: 100%), and 165% cell number increase (max: 300%); this mechanical cue is required for organ growth as guts not subject to tension do not grow. We demonstrate that growth results from increased cell proliferation when tension is applied. These results outline the essential role played by mechanical forces in shaping and driving the proliferation of embryonic organs.

Nicolas R. Chevalier - One of the best experts on this subject based on the ideXlab platform.

  • mechanical tension drives elongational growth of the embryonic gut
    Scientific Reports, 2018
    Co-Authors: Nicolas R. Chevalier, Tinkemarie De Witte, Annemiek J M Cornelissen, Sylvie Dufour, Veronique Prouxgillardeaux, Atef Asnacios
    Abstract:

    During embryonic development, most organs are in a state of mechanical compression because they grow in a confined and limited amount of space within the embryo’s body; the early gut is an exception because it physiologically herniates out of the coelom. We demonstrate here that physiological hernia is caused by a tensile force transmitted by the Vitelline Duct on the early gut loop at its attachment point at the umbilicus. We quantify this tensile force and show that applying tension for 48 h induces stress-dependent elongational growth of the embryonic gut in culture, with an average 90% length increase (max: 200%), 65% volume increase (max: 160%), 50% dry mass increase (max: 100%), and 165% cell number increase (max: 300%); this mechanical cue is required for organ growth as guts not subject to tension do not grow. We demonstrate that growth results from increased cell proliferation when tension is applied. These results outline the essential role played by mechanical forces in shaping and driving the proliferation of embryonic organs.

Blend, Charles K. - One of the best experts on this subject based on the ideXlab platform.

  • FIGURES 4–6 in Re-evaluation of Tellervotrema katadara (Kuramochi, 2001) Kuramochi, 2009 (Opecoelidae: Plagioporinae) and supplementary morphological data for T. beringi (Mamaev, 1965) Gibson & Bray, 1982 with new host and locality
    2015
    Co-Authors: Blend, Charles K., Kuramochi Toshiaki, Dronen, Norman O.
    Abstract:

    FIGURES 4–6. Tellervotrema beringi (Mamaev, 1965) Gibson & Bray, 1982 from the longfin grenadier, Coryphaenoides longifilis Günther. 4. Composite drawing of whole specimen, dorsal view (Note: Ceca are dorsal to features herein but are illustrated ventral for ease of observation). 5. Male terminal genitalia, ventral view. 6. Composite drawing of oötype region, dorsal view (Note: OviDuct is ventral to transverse Vitelline Ducts but illustrated dorsal to view former). Abbreviations: At, anterior testis; C, cecum; Cp, cirrus pouch; Dsc, dark-stained cells; E, egg; Ep, excretory pore; Ev, excretory vesicle; Gp, genital pore; Lc, Laurer's canal; M, metraterm; Mg, Mehlis' gland; O, ovary; Oes, oesophagus; Os, oral sucker; Ov, oviDuct; P, pharynx; Pc, prostate gland-cells; Pp, pars prostatica; Pt, posterior testis; Sr, seminal receptacle; Sv, seminal vesicle; U, uterus; V, Vitelline follicles; Vd, Vitelline Duct; Vr, Vitelline reservoir; Vs, ventral sucker. Scale-bars: 4, 350 µm; 5, 185 µm; 6, 135 µm

  • FIGURES 1–3 in Re-evaluation of Tellervotrema katadara (Kuramochi, 2001) Kuramochi, 2009 (Opecoelidae: Plagioporinae) and supplementary morphological data for T. beringi (Mamaev, 1965) Gibson & Bray, 1982 with new host and locality
    2015
    Co-Authors: Blend, Charles K., Kuramochi Toshiaki, Dronen, Norman O.
    Abstract:

    FIGURES 1–3. Tellervotrema katadara (Kuramochi, 2001) Kuramochi, 2009 from the bathygadine macrourid Gadomus colletti Jordan & Gilbert. 1. Holotype specimen, ventral view. 2. Male terminal genitalia of holotype specimen, ventral view. 3. Oötype region of holotype specimen, ventral view (Note: Mehlis' gland cells illustrated dorsal to all features for ease of observation; Vitelline Ducts are ventral to Laurer's canal but illustrated dorsal to view opening of latter; Vitelline reservoir not observed in holotype, but Vitelline material seen entering oviDuct within Duct from Vitelline reservoir [Vr]). Abbreviations: At, anterior testis; C, cecum; Cp, cirrus pouch; E, egg; Ep, excretory pore; Ev, excretory vesicle; Gp, genital pore; Lc, Laurer's canal; M, metraterm; Mg, Mehlis' gland; O, ovary; Oes, oesophagus; Os, oral sucker; Ov, oviDuct; P, pharynx; Pc, prostate gland-cells; Pp, pars prostatica; Pt, posterior testis; Sr, seminal receptacle; Sv, seminal vesicle; U, uterus; V, Vitelline follicles; Vd, Vitelline Duct; Vr, Vitelline reservoir; Vs, ventral sucker. Scale-bars: 1, 305 µm; 2, 190 µm; 3, 155 µm