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Cesar Fernandezdelaspenas - One of the best experts on this subject based on the ideXlab platform.

  • multimodal manual therapy vs pharmacological care for management of tension type headache a meta analysis of randomized trials
    Cephalalgia, 2015
    Co-Authors: Juan A Mesajimenez, Cristina Lozanolopez, Santiago Angulodiazparreno, Angel L Rodriguezfernandez, Jose L Delahozaizpurua, Cesar Fernandezdelaspenas
    Abstract:

    Background: Manual therapies are generally requested by patients with tension type headache. Objective: To compare the efficacy of multimodal manual therapy vs. pharmacological care for the management of tension type headache pain by conducting a meta-analysis of randomized controlled trials. Methods: PubMed, MEDLINE, EMBASE, AMED, CINAHL, EBSCO, Cochrane Database of Systematic Reviews, Cochrane Collaboration Trials Register, PEDro and SCOPUS were searched from their inception until June 2014. All randomized controlled trials comparing any manual therapy vs. medication care for treating tension type headache adults were included. Data were extracted and methodological quality assessed independently by two reviewers. We pooled headache frequency as the main outcome and also intensity and duration. The Weighted Mean difference between manual therapy and pharmacological care was used to determine effect sizes. Results: Five randomized controlled trials met our inclusion criteria and were included in the meta-analysis. Pooled analyses found that manual therapies were more effective than pharmacological care in reducing frequency (Weighted Mean difference –0.8036, 95% confidence interval –1.66 to –0.44; three trials), intensity (Weighted Mean difference – 0.5974, 95% confidence interval –0.8875 to –0.3073; five trials) and duration (Weighted Mean difference –0.5558, 95% confidence interval –0.9124 to –0.1992; three trials) of the headache immediately after treatment. No differences were found at longer follow-up for headache intensity (Weighted Mean difference –0.3498, 95% confidence interval –1.106 to 0.407; three trials). Conclusion: Manual therapies were associated with moderate effectiveness at short term, but similar effectiveness at longer follow-up for reducing headache frequency, intensity and duration in tension type headache than pharmacological medical drug care. However, due to the heterogeneity of the interventions, these results should be considered with caution at this stage.

  • multimodal manual therapy vs pharmacological care for management of tension type headache a meta analysis of randomized trials
    Cephalalgia, 2015
    Co-Authors: Juan A Mesajimenez, Cristina Lozanolopez, Santiago Angulodiazparreno, Angel L Rodriguezfernandez, Jose L Delahozaizpurua, Cesar Fernandezdelaspenas
    Abstract:

    Background: Manual therapies are generally requested by patients with tension type headache. Objective: To compare the efficacy of multimodal manual therapy vs. pharmacological care for the management of tension type headache pain by conducting a meta-analysis of randomized controlled trials. Methods: PubMed, MEDLINE, EMBASE, AMED, CINAHL, EBSCO, Cochrane Database of Systematic Reviews, Cochrane Collaboration Trials Register, PEDro and SCOPUS were searched from their inception until June 2014. All randomized controlled trials comparing any manual therapy vs. medication care for treating tension type headache adults were included. Data were extracted and methodological quality assessed independently by two reviewers. We pooled headache frequency as the main outcome and also intensity and duration. The Weighted Mean difference between manual therapy and pharmacological care was used to determine effect sizes. Results: Five randomized controlled trials met our inclusion criteria and were included in the meta-analysis. Pooled analyses found that manual therapies were more effective than pharmacological care in reducing frequency (Weighted Mean difference –0.8036, 95% confidence interval –1.66 to –0.44; three trials), intensity (Weighted Mean difference – 0.5974, 95% confidence interval –0.8875 to –0.3073; five trials) and duration (Weighted Mean difference –0.5558, 95% confidence interval –0.9124 to –0.1992; three trials) of the headache immediately after treatment. No differences were found at longer follow-up for headache intensity (Weighted Mean difference –0.3498, 95% confidence interval –1.106 to 0.407; three trials). Conclusion: Manual therapies were associated with moderate effectiveness at short term, but similar effectiveness at longer follow-up for reducing headache frequency, intensity and duration in tension type headache than pharmacological medical drug care. However, due to the heterogeneity of the interventions, these results should be considered with caution at this stage.

Juan A Mesajimenez - One of the best experts on this subject based on the ideXlab platform.

  • multimodal manual therapy vs pharmacological care for management of tension type headache a meta analysis of randomized trials
    Cephalalgia, 2015
    Co-Authors: Juan A Mesajimenez, Cristina Lozanolopez, Santiago Angulodiazparreno, Angel L Rodriguezfernandez, Jose L Delahozaizpurua, Cesar Fernandezdelaspenas
    Abstract:

    Background: Manual therapies are generally requested by patients with tension type headache. Objective: To compare the efficacy of multimodal manual therapy vs. pharmacological care for the management of tension type headache pain by conducting a meta-analysis of randomized controlled trials. Methods: PubMed, MEDLINE, EMBASE, AMED, CINAHL, EBSCO, Cochrane Database of Systematic Reviews, Cochrane Collaboration Trials Register, PEDro and SCOPUS were searched from their inception until June 2014. All randomized controlled trials comparing any manual therapy vs. medication care for treating tension type headache adults were included. Data were extracted and methodological quality assessed independently by two reviewers. We pooled headache frequency as the main outcome and also intensity and duration. The Weighted Mean difference between manual therapy and pharmacological care was used to determine effect sizes. Results: Five randomized controlled trials met our inclusion criteria and were included in the meta-analysis. Pooled analyses found that manual therapies were more effective than pharmacological care in reducing frequency (Weighted Mean difference –0.8036, 95% confidence interval –1.66 to –0.44; three trials), intensity (Weighted Mean difference – 0.5974, 95% confidence interval –0.8875 to –0.3073; five trials) and duration (Weighted Mean difference –0.5558, 95% confidence interval –0.9124 to –0.1992; three trials) of the headache immediately after treatment. No differences were found at longer follow-up for headache intensity (Weighted Mean difference –0.3498, 95% confidence interval –1.106 to 0.407; three trials). Conclusion: Manual therapies were associated with moderate effectiveness at short term, but similar effectiveness at longer follow-up for reducing headache frequency, intensity and duration in tension type headache than pharmacological medical drug care. However, due to the heterogeneity of the interventions, these results should be considered with caution at this stage.

  • multimodal manual therapy vs pharmacological care for management of tension type headache a meta analysis of randomized trials
    Cephalalgia, 2015
    Co-Authors: Juan A Mesajimenez, Cristina Lozanolopez, Santiago Angulodiazparreno, Angel L Rodriguezfernandez, Jose L Delahozaizpurua, Cesar Fernandezdelaspenas
    Abstract:

    Background: Manual therapies are generally requested by patients with tension type headache. Objective: To compare the efficacy of multimodal manual therapy vs. pharmacological care for the management of tension type headache pain by conducting a meta-analysis of randomized controlled trials. Methods: PubMed, MEDLINE, EMBASE, AMED, CINAHL, EBSCO, Cochrane Database of Systematic Reviews, Cochrane Collaboration Trials Register, PEDro and SCOPUS were searched from their inception until June 2014. All randomized controlled trials comparing any manual therapy vs. medication care for treating tension type headache adults were included. Data were extracted and methodological quality assessed independently by two reviewers. We pooled headache frequency as the main outcome and also intensity and duration. The Weighted Mean difference between manual therapy and pharmacological care was used to determine effect sizes. Results: Five randomized controlled trials met our inclusion criteria and were included in the meta-analysis. Pooled analyses found that manual therapies were more effective than pharmacological care in reducing frequency (Weighted Mean difference –0.8036, 95% confidence interval –1.66 to –0.44; three trials), intensity (Weighted Mean difference – 0.5974, 95% confidence interval –0.8875 to –0.3073; five trials) and duration (Weighted Mean difference –0.5558, 95% confidence interval –0.9124 to –0.1992; three trials) of the headache immediately after treatment. No differences were found at longer follow-up for headache intensity (Weighted Mean difference –0.3498, 95% confidence interval –1.106 to 0.407; three trials). Conclusion: Manual therapies were associated with moderate effectiveness at short term, but similar effectiveness at longer follow-up for reducing headache frequency, intensity and duration in tension type headache than pharmacological medical drug care. However, due to the heterogeneity of the interventions, these results should be considered with caution at this stage.

J Powe - One of the best experts on this subject based on the ideXlab platform.

  • incorporating quantitative single photon emission computed tomography into radiation therapy treatment planning for lung cancer impact of attenuation and scatter correction on the single photon emission computed tomography Weighted Mean dose and functional lung segmentation
    International Journal of Radiation Oncology Biology Physics, 2010
    Co-Authors: L Yin, S Shcherbinin, Anna Thompson, Anna Celler, T F Fua, Mitchell Liu, Cheryl Duzenli, B Gill, Finbar Sheehan, J Powe
    Abstract:

    Purpose To assess the impact of attenuation and scatter corrections on the calculation of single photon emission computed tomography (SPECT)–Weighted Mean dose (SWMD) and functional volume segmentation as applied to radiation therapy treatment planning for lung cancer. Methods and Materials Nine patients with lung cancer underwent a SPECT lung perfusion scan. For each scan, four image sets were reconstructed using the ordered subsets expectation maximization method with attenuation and scatter corrections ranging from none to a most comprehensive combination of attenuation corrections and direct scatter modeling. Functional volumes were segmented in each reconstructed image using 10%, 20%, …, 90% of maximum SPECT intensity as a threshold. Systematic effects of SPECT reconstruction methods on treatment planning using functional volume were studied by calculating size and spatial agreements of functional volumes, and V 20 for functional volume from actual treatment plans. The SWMD was calculated for radiation beams with a variety of possible gantry angles and field sizes. Results Functional volume segmentation is sensitive to the particular method of SPECT reconstruction used. Large variations in functional volumes, as high as >50%, were observed in SPECT images reconstructed with different attenuation/scatter corrections. However, SWMD was less sensitive to the type of scatter corrections. SWMD was consistent within 2% for all reconstructions as long as computed tomography–based attenuation correction was used. Conclusion When using perfusion SPECT images during treatment planning optimization/evaluation, the SWMD may be the preferred figure of merit, as it is less affected by reconstruction technique, compared with threshold-based functional volume segmentation.

  • su ff j 136 the impact of attenuation and scatter correction on the spect guided radiation therapy for lung cancer patients comparison of spect Weighted Mean dose and functional lung segmentation
    Medical Physics, 2009
    Co-Authors: L Yin, S Shcherbinin, Anna Thompson, Anna Celler, T F Fua, Mitchell Liu, Cheryl Duzenli, B Gill, B Sheehan, J Powe
    Abstract:

    Purpose: To investigate the impact of different types of image reconstruction and attenuation/scatter (A/S) correction on the calculation of dosimetric indices proposed to be used for Single Photon Emission Computed Tomography(SPECT) guided dose escalation in lungcancer patients. Methods and Materials:SPECTlung perfusion scans were obtained for nine lungcancer patients using 99mTc‐macroaggregated albumin. Four image sets were reconstructed from each scan: one using a vendor provided ordered subsets expectation maximization (OSEM) algorithm, two quantitative SPECTreconstructions using OSEM methods with different types of A/S corrections and the fourth an OSEM reconstruction without any A/S correction. SPECT Weighted Mean dose (SWMD), dose function histogram, and functional lung volume have been calculated from dose distributions and regional perfusion maps. To investigate the dependence of SWMDs on gantry angle, twelve equally spaced co‐planar open field radiation beams delivering the same MU were centered on the PTV. Three field sizes, 5×5, 7.5×7.5 and 10×10cm2 were considered. SWMDs were calculated for each field and reconstruction. Functional lung volumes were segmented in each reconstruction using 10, 20, …, 90% of maximum SPECT uptake as a threshold. Results: SWMDs calculated from reconstructions without A/S correction showed more than 5% average difference compared to those with corrections. With A/S corrections, more consistent SWMDs were found in all the three OSEM reconstructions (average difference ∼2%). However, a large variation was observed between segmented functional lung volumes and the V20 of these volumes in all four reconstructions. The difference between the volumes reached over 50% regardless of whether A/S correction was applied in the reconstruction.Conclusion: Functional volume segmentation is sensitive to the type of A/S correction. In contrast, SPECT Weighted Mean dose calculation produces more consistent results and appears to be a more robust choice for clinical outcome analysis and SPECT guided treatment planning.

Cristina Lozanolopez - One of the best experts on this subject based on the ideXlab platform.

  • multimodal manual therapy vs pharmacological care for management of tension type headache a meta analysis of randomized trials
    Cephalalgia, 2015
    Co-Authors: Juan A Mesajimenez, Cristina Lozanolopez, Santiago Angulodiazparreno, Angel L Rodriguezfernandez, Jose L Delahozaizpurua, Cesar Fernandezdelaspenas
    Abstract:

    Background: Manual therapies are generally requested by patients with tension type headache. Objective: To compare the efficacy of multimodal manual therapy vs. pharmacological care for the management of tension type headache pain by conducting a meta-analysis of randomized controlled trials. Methods: PubMed, MEDLINE, EMBASE, AMED, CINAHL, EBSCO, Cochrane Database of Systematic Reviews, Cochrane Collaboration Trials Register, PEDro and SCOPUS were searched from their inception until June 2014. All randomized controlled trials comparing any manual therapy vs. medication care for treating tension type headache adults were included. Data were extracted and methodological quality assessed independently by two reviewers. We pooled headache frequency as the main outcome and also intensity and duration. The Weighted Mean difference between manual therapy and pharmacological care was used to determine effect sizes. Results: Five randomized controlled trials met our inclusion criteria and were included in the meta-analysis. Pooled analyses found that manual therapies were more effective than pharmacological care in reducing frequency (Weighted Mean difference –0.8036, 95% confidence interval –1.66 to –0.44; three trials), intensity (Weighted Mean difference – 0.5974, 95% confidence interval –0.8875 to –0.3073; five trials) and duration (Weighted Mean difference –0.5558, 95% confidence interval –0.9124 to –0.1992; three trials) of the headache immediately after treatment. No differences were found at longer follow-up for headache intensity (Weighted Mean difference –0.3498, 95% confidence interval –1.106 to 0.407; three trials). Conclusion: Manual therapies were associated with moderate effectiveness at short term, but similar effectiveness at longer follow-up for reducing headache frequency, intensity and duration in tension type headache than pharmacological medical drug care. However, due to the heterogeneity of the interventions, these results should be considered with caution at this stage.

  • multimodal manual therapy vs pharmacological care for management of tension type headache a meta analysis of randomized trials
    Cephalalgia, 2015
    Co-Authors: Juan A Mesajimenez, Cristina Lozanolopez, Santiago Angulodiazparreno, Angel L Rodriguezfernandez, Jose L Delahozaizpurua, Cesar Fernandezdelaspenas
    Abstract:

    Background: Manual therapies are generally requested by patients with tension type headache. Objective: To compare the efficacy of multimodal manual therapy vs. pharmacological care for the management of tension type headache pain by conducting a meta-analysis of randomized controlled trials. Methods: PubMed, MEDLINE, EMBASE, AMED, CINAHL, EBSCO, Cochrane Database of Systematic Reviews, Cochrane Collaboration Trials Register, PEDro and SCOPUS were searched from their inception until June 2014. All randomized controlled trials comparing any manual therapy vs. medication care for treating tension type headache adults were included. Data were extracted and methodological quality assessed independently by two reviewers. We pooled headache frequency as the main outcome and also intensity and duration. The Weighted Mean difference between manual therapy and pharmacological care was used to determine effect sizes. Results: Five randomized controlled trials met our inclusion criteria and were included in the meta-analysis. Pooled analyses found that manual therapies were more effective than pharmacological care in reducing frequency (Weighted Mean difference –0.8036, 95% confidence interval –1.66 to –0.44; three trials), intensity (Weighted Mean difference – 0.5974, 95% confidence interval –0.8875 to –0.3073; five trials) and duration (Weighted Mean difference –0.5558, 95% confidence interval –0.9124 to –0.1992; three trials) of the headache immediately after treatment. No differences were found at longer follow-up for headache intensity (Weighted Mean difference –0.3498, 95% confidence interval –1.106 to 0.407; three trials). Conclusion: Manual therapies were associated with moderate effectiveness at short term, but similar effectiveness at longer follow-up for reducing headache frequency, intensity and duration in tension type headache than pharmacological medical drug care. However, due to the heterogeneity of the interventions, these results should be considered with caution at this stage.

Santiago Angulodiazparreno - One of the best experts on this subject based on the ideXlab platform.

  • multimodal manual therapy vs pharmacological care for management of tension type headache a meta analysis of randomized trials
    Cephalalgia, 2015
    Co-Authors: Juan A Mesajimenez, Cristina Lozanolopez, Santiago Angulodiazparreno, Angel L Rodriguezfernandez, Jose L Delahozaizpurua, Cesar Fernandezdelaspenas
    Abstract:

    Background: Manual therapies are generally requested by patients with tension type headache. Objective: To compare the efficacy of multimodal manual therapy vs. pharmacological care for the management of tension type headache pain by conducting a meta-analysis of randomized controlled trials. Methods: PubMed, MEDLINE, EMBASE, AMED, CINAHL, EBSCO, Cochrane Database of Systematic Reviews, Cochrane Collaboration Trials Register, PEDro and SCOPUS were searched from their inception until June 2014. All randomized controlled trials comparing any manual therapy vs. medication care for treating tension type headache adults were included. Data were extracted and methodological quality assessed independently by two reviewers. We pooled headache frequency as the main outcome and also intensity and duration. The Weighted Mean difference between manual therapy and pharmacological care was used to determine effect sizes. Results: Five randomized controlled trials met our inclusion criteria and were included in the meta-analysis. Pooled analyses found that manual therapies were more effective than pharmacological care in reducing frequency (Weighted Mean difference –0.8036, 95% confidence interval –1.66 to –0.44; three trials), intensity (Weighted Mean difference – 0.5974, 95% confidence interval –0.8875 to –0.3073; five trials) and duration (Weighted Mean difference –0.5558, 95% confidence interval –0.9124 to –0.1992; three trials) of the headache immediately after treatment. No differences were found at longer follow-up for headache intensity (Weighted Mean difference –0.3498, 95% confidence interval –1.106 to 0.407; three trials). Conclusion: Manual therapies were associated with moderate effectiveness at short term, but similar effectiveness at longer follow-up for reducing headache frequency, intensity and duration in tension type headache than pharmacological medical drug care. However, due to the heterogeneity of the interventions, these results should be considered with caution at this stage.

  • multimodal manual therapy vs pharmacological care for management of tension type headache a meta analysis of randomized trials
    Cephalalgia, 2015
    Co-Authors: Juan A Mesajimenez, Cristina Lozanolopez, Santiago Angulodiazparreno, Angel L Rodriguezfernandez, Jose L Delahozaizpurua, Cesar Fernandezdelaspenas
    Abstract:

    Background: Manual therapies are generally requested by patients with tension type headache. Objective: To compare the efficacy of multimodal manual therapy vs. pharmacological care for the management of tension type headache pain by conducting a meta-analysis of randomized controlled trials. Methods: PubMed, MEDLINE, EMBASE, AMED, CINAHL, EBSCO, Cochrane Database of Systematic Reviews, Cochrane Collaboration Trials Register, PEDro and SCOPUS were searched from their inception until June 2014. All randomized controlled trials comparing any manual therapy vs. medication care for treating tension type headache adults were included. Data were extracted and methodological quality assessed independently by two reviewers. We pooled headache frequency as the main outcome and also intensity and duration. The Weighted Mean difference between manual therapy and pharmacological care was used to determine effect sizes. Results: Five randomized controlled trials met our inclusion criteria and were included in the meta-analysis. Pooled analyses found that manual therapies were more effective than pharmacological care in reducing frequency (Weighted Mean difference –0.8036, 95% confidence interval –1.66 to –0.44; three trials), intensity (Weighted Mean difference – 0.5974, 95% confidence interval –0.8875 to –0.3073; five trials) and duration (Weighted Mean difference –0.5558, 95% confidence interval –0.9124 to –0.1992; three trials) of the headache immediately after treatment. No differences were found at longer follow-up for headache intensity (Weighted Mean difference –0.3498, 95% confidence interval –1.106 to 0.407; three trials). Conclusion: Manual therapies were associated with moderate effectiveness at short term, but similar effectiveness at longer follow-up for reducing headache frequency, intensity and duration in tension type headache than pharmacological medical drug care. However, due to the heterogeneity of the interventions, these results should be considered with caution at this stage.