The Experts below are selected from a list of 360 Experts worldwide ranked by ideXlab platform
Juisung Hung - One of the best experts on this subject based on the ideXlab platform.
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pitfalls and tips in inoue balloon mitral commissurotomy
Catheterization and Cardiovascular Diagnosis, 1996Co-Authors: Juisung HungAbstract:Balloon mitral commissurotomy is a safe and effective alternative therapeutic modality in selected patients with significant rheumatic mitral stenosis. Since its introduction in 1984, Inoue balloon mitral commissurotomy has gained Wider Acceptance over other balloon valvuloplasty techniques because it is technically less demanding and associated with fewer complications. Nevertheless, certain pitfalls which may make the procedure more difficult or create complications are sometimes encountered. In this article, we offer tips to facilitate a safe and expeditious execution of Inoue balloon mitral commissurotomy based on our experience with over 1,000 procedures. © 1996 Wiley-Liss, Inc.
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pitfalls and tips in inoue balloon mitral commissurotomy
Catheterization and Cardiovascular Diagnosis, 1996Co-Authors: Juisung Hung, Keanwah LauAbstract:Balloon mitral commissurotomy is a safe and effective alternative therapeutic modality in selected patients with significant rheumatic mitral stenosis. Since its introduction in 1984, Inoue balloon mitral commissurotomy has gained Wider Acceptance over other balloon valvuloplasty techniques because it is technically less demanding and associated with fewer complications. Nevertheless, certain pitfalls which may make the procedure more difficult or create complications are sometimes encountered. In this article, we offer tips to facilitate a safe and expeditious execution of Inoue balloon mitral commissurotomy based on our experience with over 1,000 procedures.
Mathias Jucker - One of the best experts on this subject based on the ideXlab platform.
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neurodegenerative diseases expanding the prion concept
Annual Review of Neuroscience, 2015Co-Authors: Lary C Walker, Mathias JuckerAbstract:The prion paradigm has emerged as a unifying molecular principle for the pathogenesis of many age-related neurodegenerative diseases. This paradigm holds that a fundamental cause of specific disorders is the misfolding and seeded aggregation of certain proteins. The concept arose from the discovery that devastating brain diseases called spongiform encephalopathies are transmissible to new hosts by agents consisting solely of a misfolded protein, now known as the prion protein. Accordingly, “prion” was defined as a “proteinaceous infectious particle.” As the concept has expanded to include other diseases, many of which are not infectious by any conventional definition, the designation of prions as infectious agents has become problematic. We propose to define prions as “proteinaceous nucleating particles” to highlight the molecular action of the agents, lessen unwarranted apprehension about the transmissibility of noninfectious proteopathies, and promote the Wider Acceptance of this revolutionary paradigm ...
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neurodegenerative diseases expanding the prion concept
Annual Review of Neuroscience, 2015Co-Authors: Lary C Walker, Mathias JuckerAbstract:The prion paradigm has emerged as a unifying molecular principle for the pathogenesis of many age-related neurodegenerative diseases. This paradigm holds that a fundamental cause of specific disorders is the misfolding and seeded aggregation of certain proteins. The concept arose from the discovery that devastating brain diseases called spongiform encephalopathies are transmissible to new hosts by agents consisting solely of a misfolded protein, now known as the prion protein. Accordingly, "prion" was defined as a "proteinaceous infectious particle." As the concept has expanded to include other diseases, many of which are not infectious by any conventional definition, the designation of prions as infectious agents has become problematic. We propose to define prions as "proteinaceous nucleating particles" to highlight the molecular action of the agents, lessen unwarranted apprehension about the transmissibility of noninfectious proteopathies, and promote the Wider Acceptance of this revolutionary paradigm by the biomedical community.
Keanwah Lau - One of the best experts on this subject based on the ideXlab platform.
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pitfalls and tips in inoue balloon mitral commissurotomy
Catheterization and Cardiovascular Diagnosis, 1996Co-Authors: Juisung Hung, Keanwah LauAbstract:Balloon mitral commissurotomy is a safe and effective alternative therapeutic modality in selected patients with significant rheumatic mitral stenosis. Since its introduction in 1984, Inoue balloon mitral commissurotomy has gained Wider Acceptance over other balloon valvuloplasty techniques because it is technically less demanding and associated with fewer complications. Nevertheless, certain pitfalls which may make the procedure more difficult or create complications are sometimes encountered. In this article, we offer tips to facilitate a safe and expeditious execution of Inoue balloon mitral commissurotomy based on our experience with over 1,000 procedures.
Lary C Walker - One of the best experts on this subject based on the ideXlab platform.
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neurodegenerative diseases expanding the prion concept
Annual Review of Neuroscience, 2015Co-Authors: Lary C Walker, Mathias JuckerAbstract:The prion paradigm has emerged as a unifying molecular principle for the pathogenesis of many age-related neurodegenerative diseases. This paradigm holds that a fundamental cause of specific disorders is the misfolding and seeded aggregation of certain proteins. The concept arose from the discovery that devastating brain diseases called spongiform encephalopathies are transmissible to new hosts by agents consisting solely of a misfolded protein, now known as the prion protein. Accordingly, “prion” was defined as a “proteinaceous infectious particle.” As the concept has expanded to include other diseases, many of which are not infectious by any conventional definition, the designation of prions as infectious agents has become problematic. We propose to define prions as “proteinaceous nucleating particles” to highlight the molecular action of the agents, lessen unwarranted apprehension about the transmissibility of noninfectious proteopathies, and promote the Wider Acceptance of this revolutionary paradigm ...
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neurodegenerative diseases expanding the prion concept
Annual Review of Neuroscience, 2015Co-Authors: Lary C Walker, Mathias JuckerAbstract:The prion paradigm has emerged as a unifying molecular principle for the pathogenesis of many age-related neurodegenerative diseases. This paradigm holds that a fundamental cause of specific disorders is the misfolding and seeded aggregation of certain proteins. The concept arose from the discovery that devastating brain diseases called spongiform encephalopathies are transmissible to new hosts by agents consisting solely of a misfolded protein, now known as the prion protein. Accordingly, "prion" was defined as a "proteinaceous infectious particle." As the concept has expanded to include other diseases, many of which are not infectious by any conventional definition, the designation of prions as infectious agents has become problematic. We propose to define prions as "proteinaceous nucleating particles" to highlight the molecular action of the agents, lessen unwarranted apprehension about the transmissibility of noninfectious proteopathies, and promote the Wider Acceptance of this revolutionary paradigm by the biomedical community.
Pierpaolo Sileri - One of the best experts on this subject based on the ideXlab platform.
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laparoscopic ventral rectopexy using biologic mesh for the treatment of obstructed defaecation syndrome and or faecal incontinence in patients with internal rectal prolapse a critical appraisal of the first 100 cases
Techniques in Coloproctology, 2015Co-Authors: Luana Franceschilli, D Varvaras, Ilaria Capuano, C Ciangola, Federica Giorgi, G Boehm, A L Gaspari, Pierpaolo SileriAbstract:Background Laparoscopic ventral mesh rectopexy (LVR) is gaining Wider Acceptance as the preferred procedure to correct internal as well as external rectal prolapse associated with obstructed defaecation syndrome and/or faecal incontinence. Very few reports exist on the use of biologic mesh for LVR. The aim of our study was to report the complication and recurrence rate of our first 100 cases of LVR for symptomatic internal rectal prolapse and/or rectocele using a porcine dermal collagen mesh.
