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Xiao Yu Wu - One of the best experts on this subject based on the ideXlab platform.

  • novel modified starch Xanthan Gum hydrogels for controlled drug delivery synthesis and characterization
    Carbohydrate Polymers, 2010
    Co-Authors: Alireza Shalviri, Mohammad J Abdekhodaie, Xiao Yu Wu
    Abstract:

    Abstract This work was intended to develop a new cross-linked gelatinized starch–Xanthan Gum hydrogel system, to characterize the properties of the new material, and to explore its potential applications in controlled drug delivery. Cross-linked starch–Xanthan Gum polymers were synthesized with varying levels of Xanthan Gum and sodium trimetaphosphate (STMP). The reaction of starch–Xanthan Gum polymers with STMP was examined using solid 31 P NMR spectroscopy and FTIR. Morphology of the films made from the new polymers was studied by scanning electron microscopy. The swelling properties and the network parameters such as gel mesh size of the films were investigated. The permeation of solutes with various molecular weights and charges across the films was determined. 31 P NMR and FTIR spectra showed that both starch and Xanthan Gum were reacted with STMP. The swelling ratio of the films was higher at higher STMP and Xanthan Gum levels. The gel mesh size increased with increasing swelling ratio varying from 2.84 to 6.74 nm. Permeability of anionic drugs across the polymeric films was significantly lower than their neutral form due mainly to the electrostatic repulsion between the negatively charged drugs and the polymer. The results suggest that the new cross-linked starch–Xanthan Gum hydrogels can be potentially used as a film-forming material in controlled release formulations.

Mohammad J Abdekhodaie - One of the best experts on this subject based on the ideXlab platform.

  • novel modified starch Xanthan Gum hydrogels for controlled drug delivery synthesis and characterization
    Carbohydrate Polymers, 2010
    Co-Authors: Alireza Shalviri, Mohammad J Abdekhodaie, Xiao Yu Wu
    Abstract:

    Abstract This work was intended to develop a new cross-linked gelatinized starch–Xanthan Gum hydrogel system, to characterize the properties of the new material, and to explore its potential applications in controlled drug delivery. Cross-linked starch–Xanthan Gum polymers were synthesized with varying levels of Xanthan Gum and sodium trimetaphosphate (STMP). The reaction of starch–Xanthan Gum polymers with STMP was examined using solid 31 P NMR spectroscopy and FTIR. Morphology of the films made from the new polymers was studied by scanning electron microscopy. The swelling properties and the network parameters such as gel mesh size of the films were investigated. The permeation of solutes with various molecular weights and charges across the films was determined. 31 P NMR and FTIR spectra showed that both starch and Xanthan Gum were reacted with STMP. The swelling ratio of the films was higher at higher STMP and Xanthan Gum levels. The gel mesh size increased with increasing swelling ratio varying from 2.84 to 6.74 nm. Permeability of anionic drugs across the polymeric films was significantly lower than their neutral form due mainly to the electrostatic repulsion between the negatively charged drugs and the polymer. The results suggest that the new cross-linked starch–Xanthan Gum hydrogels can be potentially used as a film-forming material in controlled release formulations.

Houjian Gong - One of the best experts on this subject based on the ideXlab platform.

  • the comparison of rheological properties of aqueous welan Gum and Xanthan Gum solutions
    Carbohydrate Polymers, 2013
    Co-Authors: Long Xu, Guiying Xu, Yijian Chen, Houjian Gong
    Abstract:

    Rheological properties of welan Gum and Xanthan Gum solutions have been characterized systematically at various concentrations, temperatures and salinities. It is found that the viscoelasticity of welan Gum is higher than that of Xanthan Gum at the same condition though the molecular weight of welan Gum is lower. In view of this, welan Gum will make a good performance in enhanced oil recovery, especially in high temperature and high salinity reservoirs. Network structure can be formed in solutions of welan Gum and Xanthan Gum for the dynamic modulus has exponential relationship with the concentration. Moreover, the molecular aggregates of welan Gum adopt a different arrangement with that of Xanthan Gum, adjacent double helices of welan Gum arrange in parallel as the zipper model. The structure formed by zipper model is still stable in high temperature and high salinity.

Vijayakumar Jayaraman - One of the best experts on this subject based on the ideXlab platform.

Alireza Shalviri - One of the best experts on this subject based on the ideXlab platform.

  • novel modified starch Xanthan Gum hydrogels for controlled drug delivery synthesis and characterization
    Carbohydrate Polymers, 2010
    Co-Authors: Alireza Shalviri, Mohammad J Abdekhodaie, Xiao Yu Wu
    Abstract:

    Abstract This work was intended to develop a new cross-linked gelatinized starch–Xanthan Gum hydrogel system, to characterize the properties of the new material, and to explore its potential applications in controlled drug delivery. Cross-linked starch–Xanthan Gum polymers were synthesized with varying levels of Xanthan Gum and sodium trimetaphosphate (STMP). The reaction of starch–Xanthan Gum polymers with STMP was examined using solid 31 P NMR spectroscopy and FTIR. Morphology of the films made from the new polymers was studied by scanning electron microscopy. The swelling properties and the network parameters such as gel mesh size of the films were investigated. The permeation of solutes with various molecular weights and charges across the films was determined. 31 P NMR and FTIR spectra showed that both starch and Xanthan Gum were reacted with STMP. The swelling ratio of the films was higher at higher STMP and Xanthan Gum levels. The gel mesh size increased with increasing swelling ratio varying from 2.84 to 6.74 nm. Permeability of anionic drugs across the polymeric films was significantly lower than their neutral form due mainly to the electrostatic repulsion between the negatively charged drugs and the polymer. The results suggest that the new cross-linked starch–Xanthan Gum hydrogels can be potentially used as a film-forming material in controlled release formulations.