The Experts below are selected from a list of 285 Experts worldwide ranked by ideXlab platform
Thierry Brotin - One of the best experts on this subject based on the ideXlab platform.
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Enantiopure [Cs$^+$/Xe$\subset$Cryptophane]$\subset$Fe$^{II}$$_4$L$_4$ Hierarchical Superstructures
Journal of the American Chemical Society, 2019Co-Authors: Dawei Zhang, Thierry Brotin, Tanya K. Ronson, Patrick Berthault, Jun-long Zhu, Jake Greenfield, Estelle Léonce, Jonathan NitschkeAbstract:Hierarchically nested hosts offer new opportunities to control the guest binding of the inner host, functionalize the cavity of the outer host, and investigate communication between different layers. Here we report a self-assembled triazatruxene-based Fe$^{II}$$_4$L$_4$ capsule, which was able to encapsulate a covalent cage, cryptophane-111 (CRY). The resulting cage-in-cage complex was capable of accommodating a cesium cation or Xenon Atom with altered guest binding behavior compared to the CRY alone. A crystal structure of the Russian doll complex [Cs$^+$/Xe$\subset$CRY]$\subset$Fe$^{II}$$_4$L$_4$ unambiguously demonstrated the unusual encapsulation of a cation within a capsule bearing a 8+ charge. Moreover, the binding of enantiopure CRY occurred with high enantioselectivity (530-fold) between the two enantiomers of the tetrahedron. This discrimination resulted in stereochemical information transfer from the inner covalent cage to the outer self-assembled capsule, leading to the formation of enantiopure [guest$\subset$cage]$\subset$cage complexes. The stereochemistry of the tetrahedron persisted even after displacement of CRY with an achiral guest.
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Enantiopure [Cs+/Xe⊂Cryptophane]⊂FeII4L4 Hierarchical Superstructures
2019Co-Authors: Dawei Zhang, Thierry Brotin, Tanya K. Ronson, Jake L. Greenfield, Patrick Berthault, Estelle Léonce, Jun-long Zhu, Jonathan R. NitschkeAbstract:Hierarchically nested hosts offer new opportunities to control the guest binding of the inner host, functionalize the cavity of the outer host, and investigate communication between different layers. Here we report a self-assembled triazatruxene-based FeII4L4 capsule, which was able to encapsulate a covalent cage, cryptophane-111 (CRY). The resulting cage-in-cage complex was capable of accommodating a cesium cation or Xenon Atom with altered guest binding behavior compared to the CRY alone. A crystal structure of the Russian doll complex [Cs+⊂CRY]⊂FeII4L4 unambiguously demonstrated the unusual encapsulation of a cation within a capsule bearing a 8+ charge. Moreover, the binding of enantiopure CRY occurred with high enantioselectivity (530-fold) between the two enantiomers of the tetrahedron. This discrimination resulted in stereochemical information transfer from the inner covalent cage to the outer self-assembled capsule, leading to the formation of enantiopure [guest⊂cage]⊂cage complexes. The stereochemistry of the tetrahedron persisted even after displacement of CRY with an achiral guest
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129xe nmr spectroscopy of deuterium labeled cryptophane a Xenon complexes investigation of host guest complexation dynamics
Journal of the American Chemical Society, 2000Co-Authors: Thierry Brotin, Anne Lesage, And Lyndon Emsley, André ColletAbstract:We have discovered the ability of 129Xe NMR spectroscopy to discriminate between the Xenon complexes of cryptophane-A 1 and its deuterated congeners 2−6 in solution. At 238 K, under slow exchange conditions, the upfield shift experienced by the Xenon Atom upon complexation by 1 (190 ppm) is increased (up to ∼0.6%) when the hosts are deuterated. By using mixtures of deuterated and nondeuterated hosts, such as 1 and 6, the dynamics of a Xenon Atom can thus be traced between three different sites (one free and two bound states). We have demonstrated that some of the dynamic features of the exchange between these sites can be extracted from 2D-EXSY experiments, using a suitable kinetic model. We conclude that the exchange of a Xenon Atom between different hosts occurs by travelling through the solution rather than upon collision of two hosts.
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129Xe NMR Spectroscopy of Deuterium-Labeled Cryptophane-A Xenon Complexes: Investigation of Host−Guest Complexation Dynamics
Journal of the American Chemical Society, 2000Co-Authors: Thierry Brotin, Anne Lesage, And Lyndon Emsley, André ColletAbstract:We have discovered the ability of 129Xe NMR spectroscopy to discriminate between the Xenon complexes of cryptophane-A 1 and its deuterated congeners 2−6 in solution. At 238 K, under slow exchange conditions, the upfield shift experienced by the Xenon Atom upon complexation by 1 (190 ppm) is increased (up to ∼0.6%) when the hosts are deuterated. By using mixtures of deuterated and nondeuterated hosts, such as 1 and 6, the dynamics of a Xenon Atom can thus be traced between three different sites (one free and two bound states). We have demonstrated that some of the dynamic features of the exchange between these sites can be extracted from 2D-EXSY experiments, using a suitable kinetic model. We conclude that the exchange of a Xenon Atom between different hosts occurs by travelling through the solution rather than upon collision of two hosts.
Jonathan Nitschke - One of the best experts on this subject based on the ideXlab platform.
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Enantiopure [Cs$^+$/Xe$\subset$Cryptophane]$\subset$Fe$^{II}$$_4$L$_4$ Hierarchical Superstructures
Journal of the American Chemical Society, 2019Co-Authors: Dawei Zhang, Thierry Brotin, Tanya K. Ronson, Patrick Berthault, Jun-long Zhu, Jake Greenfield, Estelle Léonce, Jonathan NitschkeAbstract:Hierarchically nested hosts offer new opportunities to control the guest binding of the inner host, functionalize the cavity of the outer host, and investigate communication between different layers. Here we report a self-assembled triazatruxene-based Fe$^{II}$$_4$L$_4$ capsule, which was able to encapsulate a covalent cage, cryptophane-111 (CRY). The resulting cage-in-cage complex was capable of accommodating a cesium cation or Xenon Atom with altered guest binding behavior compared to the CRY alone. A crystal structure of the Russian doll complex [Cs$^+$/Xe$\subset$CRY]$\subset$Fe$^{II}$$_4$L$_4$ unambiguously demonstrated the unusual encapsulation of a cation within a capsule bearing a 8+ charge. Moreover, the binding of enantiopure CRY occurred with high enantioselectivity (530-fold) between the two enantiomers of the tetrahedron. This discrimination resulted in stereochemical information transfer from the inner covalent cage to the outer self-assembled capsule, leading to the formation of enantiopure [guest$\subset$cage]$\subset$cage complexes. The stereochemistry of the tetrahedron persisted even after displacement of CRY with an achiral guest.
André Collet - One of the best experts on this subject based on the ideXlab platform.
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129xe nmr spectroscopy of deuterium labeled cryptophane a Xenon complexes investigation of host guest complexation dynamics
Journal of the American Chemical Society, 2000Co-Authors: Thierry Brotin, Anne Lesage, And Lyndon Emsley, André ColletAbstract:We have discovered the ability of 129Xe NMR spectroscopy to discriminate between the Xenon complexes of cryptophane-A 1 and its deuterated congeners 2−6 in solution. At 238 K, under slow exchange conditions, the upfield shift experienced by the Xenon Atom upon complexation by 1 (190 ppm) is increased (up to ∼0.6%) when the hosts are deuterated. By using mixtures of deuterated and nondeuterated hosts, such as 1 and 6, the dynamics of a Xenon Atom can thus be traced between three different sites (one free and two bound states). We have demonstrated that some of the dynamic features of the exchange between these sites can be extracted from 2D-EXSY experiments, using a suitable kinetic model. We conclude that the exchange of a Xenon Atom between different hosts occurs by travelling through the solution rather than upon collision of two hosts.
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129Xe NMR Spectroscopy of Deuterium-Labeled Cryptophane-A Xenon Complexes: Investigation of Host−Guest Complexation Dynamics
Journal of the American Chemical Society, 2000Co-Authors: Thierry Brotin, Anne Lesage, And Lyndon Emsley, André ColletAbstract:We have discovered the ability of 129Xe NMR spectroscopy to discriminate between the Xenon complexes of cryptophane-A 1 and its deuterated congeners 2−6 in solution. At 238 K, under slow exchange conditions, the upfield shift experienced by the Xenon Atom upon complexation by 1 (190 ppm) is increased (up to ∼0.6%) when the hosts are deuterated. By using mixtures of deuterated and nondeuterated hosts, such as 1 and 6, the dynamics of a Xenon Atom can thus be traced between three different sites (one free and two bound states). We have demonstrated that some of the dynamic features of the exchange between these sites can be extracted from 2D-EXSY experiments, using a suitable kinetic model. We conclude that the exchange of a Xenon Atom between different hosts occurs by travelling through the solution rather than upon collision of two hosts.
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Molecular polarization and molecular chiralization: The first example of a chiralized Xenon Atom.
Chirality, 2000Co-Authors: Kristin Bartik, André Collet, Michel Luhmer, Jacques ReisseAbstract:In this article we focus on the interaction between a chiral molecule and a single achiral molecule or an ensemble of achiral molecules. The desymmetrization of the achiral molecules resulting from this interaction is described as "chiralization." By analogy with electric polarization, we factorize chiralization into three factors, i.e., orientation, Atomic, and electronic terms. Chiralization depends on the dipolar polarizability of the chiralized molecule but also on polarizabilities of higher order. The experimental part of this work is devoted to the electronic chiralization of a Xenon Atom and its observation by (129)Xe NMR spectroscopy. Copyright 2000 Wiley-Liss, Inc.
Dawei Zhang - One of the best experts on this subject based on the ideXlab platform.
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Enantiopure [Cs$^+$/Xe$\subset$Cryptophane]$\subset$Fe$^{II}$$_4$L$_4$ Hierarchical Superstructures
Journal of the American Chemical Society, 2019Co-Authors: Dawei Zhang, Thierry Brotin, Tanya K. Ronson, Patrick Berthault, Jun-long Zhu, Jake Greenfield, Estelle Léonce, Jonathan NitschkeAbstract:Hierarchically nested hosts offer new opportunities to control the guest binding of the inner host, functionalize the cavity of the outer host, and investigate communication between different layers. Here we report a self-assembled triazatruxene-based Fe$^{II}$$_4$L$_4$ capsule, which was able to encapsulate a covalent cage, cryptophane-111 (CRY). The resulting cage-in-cage complex was capable of accommodating a cesium cation or Xenon Atom with altered guest binding behavior compared to the CRY alone. A crystal structure of the Russian doll complex [Cs$^+$/Xe$\subset$CRY]$\subset$Fe$^{II}$$_4$L$_4$ unambiguously demonstrated the unusual encapsulation of a cation within a capsule bearing a 8+ charge. Moreover, the binding of enantiopure CRY occurred with high enantioselectivity (530-fold) between the two enantiomers of the tetrahedron. This discrimination resulted in stereochemical information transfer from the inner covalent cage to the outer self-assembled capsule, leading to the formation of enantiopure [guest$\subset$cage]$\subset$cage complexes. The stereochemistry of the tetrahedron persisted even after displacement of CRY with an achiral guest.
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Enantiopure [Cs+/Xe⊂Cryptophane]⊂FeII4L4 Hierarchical Superstructures
2019Co-Authors: Dawei Zhang, Thierry Brotin, Tanya K. Ronson, Jake L. Greenfield, Patrick Berthault, Estelle Léonce, Jun-long Zhu, Jonathan R. NitschkeAbstract:Hierarchically nested hosts offer new opportunities to control the guest binding of the inner host, functionalize the cavity of the outer host, and investigate communication between different layers. Here we report a self-assembled triazatruxene-based FeII4L4 capsule, which was able to encapsulate a covalent cage, cryptophane-111 (CRY). The resulting cage-in-cage complex was capable of accommodating a cesium cation or Xenon Atom with altered guest binding behavior compared to the CRY alone. A crystal structure of the Russian doll complex [Cs+⊂CRY]⊂FeII4L4 unambiguously demonstrated the unusual encapsulation of a cation within a capsule bearing a 8+ charge. Moreover, the binding of enantiopure CRY occurred with high enantioselectivity (530-fold) between the two enantiomers of the tetrahedron. This discrimination resulted in stereochemical information transfer from the inner covalent cage to the outer self-assembled capsule, leading to the formation of enantiopure [guest⊂cage]⊂cage complexes. The stereochemistry of the tetrahedron persisted even after displacement of CRY with an achiral guest
Jake Greenfield - One of the best experts on this subject based on the ideXlab platform.
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Enantiopure [Cs$^+$/Xe$\subset$Cryptophane]$\subset$Fe$^{II}$$_4$L$_4$ Hierarchical Superstructures
Journal of the American Chemical Society, 2019Co-Authors: Dawei Zhang, Thierry Brotin, Tanya K. Ronson, Patrick Berthault, Jun-long Zhu, Jake Greenfield, Estelle Léonce, Jonathan NitschkeAbstract:Hierarchically nested hosts offer new opportunities to control the guest binding of the inner host, functionalize the cavity of the outer host, and investigate communication between different layers. Here we report a self-assembled triazatruxene-based Fe$^{II}$$_4$L$_4$ capsule, which was able to encapsulate a covalent cage, cryptophane-111 (CRY). The resulting cage-in-cage complex was capable of accommodating a cesium cation or Xenon Atom with altered guest binding behavior compared to the CRY alone. A crystal structure of the Russian doll complex [Cs$^+$/Xe$\subset$CRY]$\subset$Fe$^{II}$$_4$L$_4$ unambiguously demonstrated the unusual encapsulation of a cation within a capsule bearing a 8+ charge. Moreover, the binding of enantiopure CRY occurred with high enantioselectivity (530-fold) between the two enantiomers of the tetrahedron. This discrimination resulted in stereochemical information transfer from the inner covalent cage to the outer self-assembled capsule, leading to the formation of enantiopure [guest$\subset$cage]$\subset$cage complexes. The stereochemistry of the tetrahedron persisted even after displacement of CRY with an achiral guest.
