The Experts below are selected from a list of 6816 Experts worldwide ranked by ideXlab platform
Mark A. Jepson - One of the best experts on this subject based on the ideXlab platform.
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M-Cell Surface β1 Integrin Expression and Invasin-Mediated Targeting of Yersinia pseudotuberculosis to Mouse Peyer’s Patch M Cells
Infection and immunity, 1998Co-Authors: M. Ann Clark, Barry H. Hirst, Mark A. JepsonAbstract:Quantitative analysis of Yersinia pseudotuberculosis infection of murine gut loops revealed that significantly more wild-type bacteria associated with Peyer’s patch M cells than with dome enterocytes or goblet cells. An invasin-deficient mutant was significantly attenuated for M-cell invasion, while β1 integrin expression was demonstrated in the apical membranes of M cells but not enterocytes. M-cell targeting by Yersinia pseudotuberculosis in vivo may, therefore, be mediated primarily by the interaction of invasin with cell surface β1 integrins.
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m cell surface β1 integrin expression and invasin mediated targeting of Yersinia pseudotuberculosis to mouse peyer s patch m cells
Infection and Immunity, 1998Co-Authors: Ann M Clark, Barry H. Hirst, Mark A. JepsonAbstract:Quantitative analysis of Yersinia pseudotuberculosis infection of murine gut loops revealed that significantly more wild-type bacteria associated with Peyer’s patch M cells than with dome enterocytes or goblet cells. An invasin-deficient mutant was significantly attenuated for M-cell invasion, while β1 integrin expression was demonstrated in the apical membranes of M cells but not enterocytes. M-cell targeting by Yersinia pseudotuberculosis in vivo may, therefore, be mediated primarily by the interaction of invasin with cell surface β1 integrins.
Maria Fällman - One of the best experts on this subject based on the ideXlab platform.
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Transcriptomic and phenotypic analysis of sufI and tatC mutants of Yersinia pseudotuberculosis
2016Co-Authors: Ummehan Avican, Kemal Avican, Maria Fällman, Åke ForsbergAbstract:Transcriptomic and phenotypic analysis of sufI and tatC mutants of Yersinia pseudotuberculosis
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Transcriptomic characterization of RfaH linked to persistent infection of Yersinia pseudotuberculosis
2015Co-Authors: Kemal Avican, Karin Nilsson, Maria FällmanAbstract:Transcriptomic characterization of RfaH linked to persistent infection of Yersinia pseudotuberculosis
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Cell type-specific effects of Yersinia pseudotuberculosis virulence effectors.
Cellular microbiology, 2009Co-Authors: Anna Fahlgren, Linda Westermark, Karen Akopyan, Maria FällmanAbstract:One important feature of Yersinia pseudotuberculosis that enables resistance against the host immune defence is delivery of the antiphagocytic effectors YopH and YopE into phagocytic cells. The tyr ...
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YopH of Yersinia pseudotuberculosis interrupts early phosphotyrosine signalling associated with phagocytosis.
Molecular microbiology, 1996Co-Authors: K. Kristoffer Andersson, Nivia Carballeira, Karl-eric Magnusson, Cathrine Persson, Olle Stendahl, Hans Wolf-watz, Maria FällmanAbstract:The PTPase YopH of Yersinia is essential to the ability of these bacteria to block phagocytosis. Wild-type Yersinia pseudotuberculosis, but not the yopH mutant strain, resisted phagocytosis by J774 ...
Hans Wolf-watz - One of the best experts on this subject based on the ideXlab platform.
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The membrane localization domain is required for intracellular localization and autoregulation of YopE in Yersinia pseudotuberculosis
Infection and immunity, 2009Co-Authors: Elin L. Isaksson, Anna Fahlgren, Margareta Aili, Roland Rosqvist, Sara E. Carlsson, Hans Wolf-watzAbstract:Recent work has shown that a domain of YopE of Yersinia pseudotuberculosis ranging from amino acids 54 to 75 (R. Krall, Y. Zhang, and J. T. Barbieri, J. Biol. Chem. 279:2747-2753, 2004) is required ...
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Functional analysis of the YopE GTPase‐activating protein (GAP) activity of Yersinia pseudotuberculosis
Cellular microbiology, 2006Co-Authors: Margareta Aili, Hans Wolf-watz, Elin L. Isaksson, Bengt Hallberg, Roland RosqvistAbstract:YopE of Yersinia pseudotuberculosis inactivates three members of the small RhoGTPase family (RhoA, Rac1 and Cdc42) in vitro and mutation of a critical arginine abolishes both in vitro GTPase-activa ...
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YopH of Yersinia pseudotuberculosis interrupts early phosphotyrosine signalling associated with phagocytosis.
Molecular microbiology, 1996Co-Authors: K. Kristoffer Andersson, Nivia Carballeira, Karl-eric Magnusson, Cathrine Persson, Olle Stendahl, Hans Wolf-watz, Maria FällmanAbstract:The PTPase YopH of Yersinia is essential to the ability of these bacteria to block phagocytosis. Wild-type Yersinia pseudotuberculosis, but not the yopH mutant strain, resisted phagocytosis by J774 ...
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Invasin of Yersinia pseudotuberculosis activates human peripheral B cells.
Infection and immunity, 1996Co-Authors: Erik Lundgren, N Carballeira, R Vazquez, E Dubinina, H Bränden, Helena Persson, Hans Wolf-watzAbstract:The Yersinia pseudotuberculosis cell surface-located protein invasin was found to promote binding between the pathogen and resting peripheral B cells via beta 1 integrin receptors (CD29). B cells responded by expressing several activation markers and by growing, In contrast, T cells did not react, although these cells express CD29. An isogenic invA mutant failed to activate B cells. The mutation could be complemented by providing the invA+ gene in trans. Purified invasin alone did not activate B cells, although it was able to block the binding of bacteria to the cells.
Barry H. Hirst - One of the best experts on this subject based on the ideXlab platform.
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M-Cell Surface β1 Integrin Expression and Invasin-Mediated Targeting of Yersinia pseudotuberculosis to Mouse Peyer’s Patch M Cells
Infection and immunity, 1998Co-Authors: M. Ann Clark, Barry H. Hirst, Mark A. JepsonAbstract:Quantitative analysis of Yersinia pseudotuberculosis infection of murine gut loops revealed that significantly more wild-type bacteria associated with Peyer’s patch M cells than with dome enterocytes or goblet cells. An invasin-deficient mutant was significantly attenuated for M-cell invasion, while β1 integrin expression was demonstrated in the apical membranes of M cells but not enterocytes. M-cell targeting by Yersinia pseudotuberculosis in vivo may, therefore, be mediated primarily by the interaction of invasin with cell surface β1 integrins.
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m cell surface β1 integrin expression and invasin mediated targeting of Yersinia pseudotuberculosis to mouse peyer s patch m cells
Infection and Immunity, 1998Co-Authors: Ann M Clark, Barry H. Hirst, Mark A. JepsonAbstract:Quantitative analysis of Yersinia pseudotuberculosis infection of murine gut loops revealed that significantly more wild-type bacteria associated with Peyer’s patch M cells than with dome enterocytes or goblet cells. An invasin-deficient mutant was significantly attenuated for M-cell invasion, while β1 integrin expression was demonstrated in the apical membranes of M cells but not enterocytes. M-cell targeting by Yersinia pseudotuberculosis in vivo may, therefore, be mediated primarily by the interaction of invasin with cell surface β1 integrins.
Andrey P. Anisimov - One of the best experts on this subject based on the ideXlab platform.
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Draft Genome Sequences of Five Yersinia pseudotuberculosis ST19 Isolates and One Isolate Variant.
Genome Announc, 2013Co-Authors: Mikhail E Platonov, Yann Blouin, Vera V Evseeva, Maxim V Afanas'ev, Christine Pourcel, Sergey V Balakhonov, Gilles Vergnaud, Andrey P. AnisimovAbstract:We report the first draft genome sequences of five Yersinia pseudotuberculosis isolates of sequence type (ST) 19 and of a variant from one of the five isolates. The total length of assemblies ranged from 4,226,485 bp to 4,274,148 bp, including between 3,808 and 3,843 predicted coding sequences.
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Structure of the O-polysaccharide of Yersinia pseudotuberculosis O:2b
Carbohydrate Research, 2009Co-Authors: Anna N. Kondakova, Olga V. Bystrova, Rima Z. Shaikhutdinova, Sergey A. Ivanov, Svetlana V. Dentovskaya, Alexander S. Shashkov, Yuriy A. Knirel, Andrey P. AnisimovAbstract:Abstract The O-polysaccharide was isolated by hydrolysis of the lipopolysaccharide of Yersinia pseudotuberculosis O:2b, and studied by 1D and 2D NMR spectroscopy. The following structure of the polysaccharide was established: Download : Download full-size image where Abe stands for 3,6-dideoxy- d -xylo-hexose (abequose).
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Structure of the O-antigen of Yersinia pseudotuberculosis O:4b.
Carbohydrate research, 2008Co-Authors: Anna N. Kondakova, Olga V. Bystrova, Rima Z. Shaikhutdinova, Sergey A. Ivanov, Svetlana V. Dentovskaya, Alexander S. Shashkov, Yuriy A. Knirel, Andrey P. AnisimovAbstract:Abstract The structure of the long-chain O-antigen of Yersinia pseudotuberculosis O:4b containing two uncommon deoxy sugars, tyvelose (3,6-dideoxy- d -arabino-hexose, Tyv) and 6-deoxy- d -manno-heptose ( d -6dmanHep), was established by 1D and 2D NMR spectroscopy as Download : Download full-size image