The Experts below are selected from a list of 1452 Experts worldwide ranked by ideXlab platform
Wei Qin - One of the best experts on this subject based on the ideXlab platform.
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imprinted nanobead based disposable screen printed potentiometric sensor for highly sensitive detection of 2 Naphthoic Acid
2018Co-Authors: Rongning Liang, Xiaofeng Yang, Wei QinAbstract:Abstract Currently, potentiometric sensors based on various molecularly imprinted polymer (MIP) receptors have been successfully fabricated for detection of organic species. However, almost all of the previously developed potentiometric sensors based on MIPs are in traditional liquid-contact mode in which lower detection limits have been restricted by zero-current transmembrane ion fluxes. Herein, a screen-printed potentiometric sensor for determination of 2-Naphthoic Acid has been developed. It is based on the MIP nanobeads as the selective receptor and the electrochemically reduced graphene oxide film as the solid contact. Compared with the classical potentiometric sensor, the proposed sensor based on nonequilibrium sensing mechanism exhibits remarkably improved detection sensitivity for 2-Naphthoic Acid with a low detection limit of 6.9 × 10−11 M.
Anatoly A Soshilov - One of the best experts on this subject based on the ideXlab platform.
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editor s highlight microbial derived 1 4 dihydroxy 2 Naphthoic Acid and related compounds as aryl hydrocarbon receptor agonists antagonists structure activity relationships and receptor modeling
2017Co-Authors: Yating Cheng, Un-ho Jin, Laurie A Davidson, Robert S Chapkin, Arul Jayaraman, Phanourios Tamamis, Asuka A Orr, Clint D Allred, Michael S Denison, Anatoly A SoshilovAbstract:1,4-Dihydroxy-2-Naphthoic Acid (1,4-DHNA) is a bacterial-derived metabolite that binds the aryl hydrocarbon receptor (AhR) and exhibits anti-inflammatory activity in the gut. The structure-dependent AhR activity of hydroxyl/carboxy-substituted Naphthoic Acids (NAs) was determined in young adult mouse colonic (YAMC) cells and human Caco2 colon cancer cells using CYP1A1/CYP1B1 mRNAs as Ah-responsive genes. Compounds used in this study include 1,4-, 3,5-, and 3,7-DHNA, 1,4-dimethoxy-2-Naphthoic Acid (1,4-DMNA), 1- and 4-hydroxy-2-Naphthoic Acid (1-HNA, 4-HNA), 1- and 2-Naphthoic Acid (1-NA, 2-NA), and 1- and 2-naphthol (1-NOH, 2-NOH). 1,4-DHNA was the most potent compound among hydroxyl/carboxy naphthalene derivatives, and the fold induction response for CYP1A1 and CYP1B1 was similar to that observed for 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in YAMC and Caco2 cells. 1- and 4-HNA were less potent than 1,4-DHNA but induced maximal (TCDD-like) response for CYP1B1 (both cell lines) and CYP1A1 (Caco2 cells). With the exception of 1- and 2-NA, all compounds significantly induced Cyp1b1 in YAMC cells and these responses were not observed in AhR-deficient YAMC cells generated using CRISPR/Cas9 technology. In addition, we also observed that 1- and 2-NOH (and 1,4-DHNA) were weak AhR agonists, and 1- and 2-NOH also exhibited partial AhR antagonist activity. Structure-activity relationship studies for CYP1A1 but not CYP1B1 were similar in both cell lines, and CYP1A1 induction required one or both 1,4-dihydroxy substituents and activity was significantly enhanced by the 2-carboxyl group. We also used computational analysis to show that 1,4-DHNA and TCDD share similar interactions within the AhR binding pocket and differ primarily due to the negatively charged group of 1,4-DHNA.
Wen Dong - One of the best experts on this subject based on the ideXlab platform.
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structures single molecule magnets and fluorescent properties of four dinuclear lanthanide complexes based on 4 azotriazolyl 3 hydroxy 2 Naphthoic Acid
2019Co-Authors: Shang-fang Xie, Li-qian Huang, Li Zhong, Bi-lin Lai, Meng Yang, Wen-bin Chen, Yi-quan Zhang, Wen DongAbstract:Four isostructural dinuclear lanthanide complexes based on 4-azotriazolyl-3-hydroxy-2-Naphthoic Acid (H3ATNA) and 3-hydroxy-2-Naphthoic Acid (H2NA) ligands, {[Ln2(HATNA)2(HNA)2(H2O)4]·6DMF} (Ln = Dy (1), Tb (2), Sm (3), Eu (4); DMF = N, N-dimethylformamide) have been prepared and characterized by X-ray diffraction crystallography, dc/ac magnetic characterization, and fluorescent spectrometry. The crystallographic data reveal dinuclear lanthanide cores of complexes 1-4, bridged by phenoxo and μ1,3 carboxyl groups. Each nine-coordinated Ln(III) ion is located in a slightly distorted monocapped square antiprism. The ligand of H3ATNA displays a unique antenna effect in complex 4. Complexes 1-3 display only two ligand-centered fluorescent emissive peaks around 450 and 600 nm, and complex 4 shows four characteristic Eu(III)-centered emission bands at 593, 618, 653, and 698 nm under excitation at 348 nm. Complex 1 exhibits single-molecule magnet behavior that is rationalized through ab initio calculations.
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Structures, Single-Molecule Magnets, and Fluorescent Properties of Four Dinuclear Lanthanide Complexes Based on 4‑Azotriazolyl-3-hydroxy-2-Naphthoic Acid
2019Co-Authors: Shang-fang Xie, Li-qian Huang, Li Zhong, Bi-lin Lai, Meng Yang, Wen-bin Chen, Yi-quan Zhang, Wen DongAbstract:Four isostructural dinuclear lanthanide complexes based on 4-azotriazolyl-3-hydroxy-2-Naphthoic Acid (H3ATNA) and 3-hydroxy-2-Naphthoic Acid (H2NA) ligands, {[Ln2(HATNA)2(HNA)2(H2O)4]·6DMF} (Ln = Dy (1), Tb (2), Sm (3), Eu (4); DMF = N,N-dimethylformamide) have been prepared and characterized by X-ray diffraction crystallography, dc/ac magnetic characterization, and fluorescent spectrometry. The crystallographic data reveal dinuclear lanthanide cores of complexes 1–4, bridged by phenoxo and μ1,3 carboxyl groups. Each nine-coordinated Ln(III) ion is located in a slightly distorted monocapped square antiprism. The ligand of H3ATNA displays a unique antenna effect in complex 4. Complexes 1–3 display only two ligand-centered fluorescent emissive peaks around 450 and 600 nm, and complex 4 shows four characteristic Eu(III)-centered emission bands at 593, 618, 653, and 698 nm under excitation at 348 nm. Complex 1 exhibits single-molecule magnet behavior that is rationalized through ab initio calculations
Rongning Liang - One of the best experts on this subject based on the ideXlab platform.
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imprinted nanobead based disposable screen printed potentiometric sensor for highly sensitive detection of 2 Naphthoic Acid
2018Co-Authors: Rongning Liang, Xiaofeng Yang, Wei QinAbstract:Abstract Currently, potentiometric sensors based on various molecularly imprinted polymer (MIP) receptors have been successfully fabricated for detection of organic species. However, almost all of the previously developed potentiometric sensors based on MIPs are in traditional liquid-contact mode in which lower detection limits have been restricted by zero-current transmembrane ion fluxes. Herein, a screen-printed potentiometric sensor for determination of 2-Naphthoic Acid has been developed. It is based on the MIP nanobeads as the selective receptor and the electrochemically reduced graphene oxide film as the solid contact. Compared with the classical potentiometric sensor, the proposed sensor based on nonequilibrium sensing mechanism exhibits remarkably improved detection sensitivity for 2-Naphthoic Acid with a low detection limit of 6.9 × 10−11 M.
Keren Shi - One of the best experts on this subject based on the ideXlab platform.
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luminescence tuning of layered rare earth hydroxides lrhs r tb y composites with 3 hydroxy 2 Naphthoic Acid and application to the fluorescent detection of al3
2019Co-Authors: Rong Guo, Hui Wang, Yuexin Guo, Huiqin Yao, Gailing Huang, Zupei Liang, Keren ShiAbstract:Tunable luminescence (quenching or blue shift) of HNA/OS-LRH composites (HNA is 3-hydroxy-2-Naphthoic Acid; OS is the anionic surfactant of 1-octanesulfonic Acid sodium; LRHs are layered rare-earth...
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luminescence tuning of layered rare earth hydroxides lrhs r tb y composites with 3 hydroxy 2 Naphthoic Acid and application to the fluorescent detection of al3
2019Co-Authors: Rong Guo, Hui Wang, Yuexin Guo, Huiqin Yao, Gailing Huang, Zupei Liang, Keren ShiAbstract:Tunable luminescence (quenching or blue shift) of HNA/OS-LRH composites (HNA is 3-hydroxy-2-Naphthoic Acid; OS is the anionic surfactant of 1-octanesulfonic Acid sodium; LRHs are layered rare-earth hydroxides, R = Tb3+, Y3+) in the solid state and delaminated state is reported, which is utilized as an effective fluorescent probe for detecting metal ions. HNA/OS species are intercalated into LRH layers to generate composites of HNA xOS1- x-LTbH ( x = 0.10, 0.15, 0.20 , 0.25) and HNA yOS1- y-LYH ( y = 0.05, 0.10, 0.15, 0.20, 0.25, 0.30). In the solid state, LYH composites exhibit green emissions (from 493 to 504 nm) with a large blue shift in comparison to the 542 nm emission of free HNA- anions, while in the delaminated state in formamide (FM), the composites display blue emission (480 nm) relative to the green emission (512 nm) of an HNA soltuion in FM. However, LTbH composites display coquenched luminescence in both the solid state and delaminated state. Also, HNA0.25OS0.75-1:1-LYH, HNA0.25OS0.75-1:2-LYH, and HNA0.05OS0.95-1:1-LYH (1:1 and 1:2 are HNA:NaOH molar ratios) show significantly elongated fluorescence lifetimes of 15.35, 14.37, and 12.72 ns, respectively, in comparison with free HNA-Na (6.44 ns), and their quantum yields of 23.40%, 21.97%, and 22.31%, respectively, are much larger than that of free HNA-Na (4.86%). The LTbH composite (HNA0.25OS0.75-1:1-LTbH) has also a relatively higher quantum yield of 12.46%. The HNA0.25OS0.75-1:1-LYH colloid exhibits excellent recognition selectivity for Al3+ over other metal ions (Mg2+, Co2+, Ni2+, Cu2+, Zn2+, Pb2+, Cd2+, and Hg2+) with distinct fluorescence sensitization. It shows an intense change in its fluorescence emission when it is bound to Al3+ ions, giving a lower detection limit of 6.32 × 10-6 M. This is novel research on the fluorescence chemosensing of LRH composites.
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Luminescence Tuning of Layered Rare-Earth Hydroxides (LRHs, R = Tb, Y) Composites with 3‑Hydroxy-2-Naphthoic Acid and Application to the Fluorescent Detection of Al3+
2019Co-Authors: Rong Guo, Hui Wang, Yuexin Guo, Huiqin Yao, Gailing Huang, Zupei Liang, Keren ShiAbstract:Tunable luminescence (quenching or blue shift) of HNA/OS-LRH composites (HNA is 3-hydroxy-2-Naphthoic Acid; OS is the anionic surfactant of 1-octanesulfonic Acid sodium; LRHs are layered rare-earth hydroxides, R = Tb3+, Y3+) in the solid state and delaminated state is reported, which is utilized as an effective fluorescent probe for detecting metal ions. HNA/OS species are intercalated into LRH layers to generate composites of HNAxOS1–x-LTbH (x = 0.10, 0.15, 0.20 , 0.25) and HNAyOS1–y-LYH (y = 0.05, 0.10, 0.15, 0.20, 0.25, 0.30). In the solid state, LYH composites exhibit green emissions (from 493 to 504 nm) with a large blue shift in comparison to the 542 nm emission of free HNA– anions, while in the delaminated state in formamide (FM), the composites display blue emission (480 nm) relative to the green emission (512 nm) of an HNA soltuion in FM. However, LTbH composites display coquenched luminescence in both the solid state and delaminated state. Also, HNA0.25OS0.75-1:1-LYH, HNA0.25OS0.75-1:2-LYH, and HNA0.05OS0.95-1:1-LYH (1:1 and 1:2 are HNA:NaOH molar ratios) show significantly elongated fluorescence lifetimes of 15.35, 14.37, and 12.72 ns, respectively, in comparison with free HNA-Na (6.44 ns), and their quantum yields of 23.40%, 21.97%, and 22.31%, respectively, are much larger than that of free HNA-Na (4.86%). The LTbH composite (HNA0.25OS0.75-1:1-LTbH) has also a relatively higher quantum yield of 12.46%. The HNA0.25OS0.75-1:1-LYH colloid exhibits excellent recognition selectivity for Al3+ over other metal ions (Mg2+, Co2+, Ni2+, Cu2+, Zn2+, Pb2+, Cd2+, and Hg2+) with distinct fluorescence sensitization. It shows an intense change in its fluorescence emission when it is bound to Al3+ ions, giving a lower detection limit of 6.32 × 10–6 M. This is novel research on the fluorescence chemosensing of LRH composites
