The Experts below are selected from a list of 819 Experts worldwide ranked by ideXlab platform
Rai-shung Liu - One of the best experts on this subject based on the ideXlab platform.
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Gold-Catalyzed Oxidations of 1,3-Diynamides with C(1) versus C(3) Regioselectivity: Catalyst-Dependent Oxidative Cyclizations in the C(3) Oxidation.
Organic letters, 2020Co-Authors: Manisha Skaria, Mu Jeng Cheng, Yu Chen Hsu, Yan Ting Jiang, Tung Chun Kuo, Rai-shung LiuAbstract:This work reports two distinct paths in catalytic oxidations of 1,3-diynamides with 8-Methylquinoline oxide. A typical C(1) regioselectivity was observed for aryl-substituted 1,3-diyn-1-amides, whe...
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Gold-Catalyzed Oxidation of Thioalkynes To Form Phenylthio Ketene Derivatives via a Noncarbene Route
Organic letters, 2019Co-Authors: Pankaj Sharma, Rahulkumar Rajmani Singh, Sovan Sundar Giri, Liang Yu Chen, Mu Jeng Cheng, Rai-shung LiuAbstract:Gold-catalyzed oxidations of thioalkynes with 8-Methylquinoline oxides afford 2-phenylthioketenes that can be trapped efficiently with alcohols. The synthetic utility is manifested by terminal and internal thioalkynes over a wide scope, bearing esters, ketones, alkyl, and oxime substituents. Our density functional theory calculations suggest that gold-catalyzed oxidations of terminal and internal thioalkynes with 8-Methylquinoline oxides generate gold-bound ketene intermediates without the intermediacy of α-oxo gold carbene.
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Gold-catalyzed oxidative cyclization of 4-allenyl-1-ynes with 8-Methylquinoline oxide.
Organic letters, 2013Co-Authors: Rahul Kisan Kawade, Rai-shung LiuAbstract:Gold-catalyzed oxidative cyclizations of 4-allenyl-1-ynes with 8-Methylquinoline oxide are described; diverse products are produced depending on the allenyl substituents. This reaction comprises initial formation of α-oxo gold carbenes that are attacked by allene to form allyl cation intermediates.
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Gold-catalyzed synthesis of substituted 2-aminofurans via formal [4+1]-cycloadditions on 3-en-1-ynamides
Chemical communications (Cambridge England), 2012Co-Authors: Ramesh B. Dateer, Kamalkishore Pati, Rai-shung LiuAbstract:Gold-catalyzed formal [4+1]-cycloadditions between 3-en-1-ynamides 1 and 8-Methylquinoline oxide are reported. The success of this reaction relies on a hypothetic oxa-Nazarov cyclization on gold-stabilized allylic cations. Preliminary results on a new 1,2-difunctionalization of 3-en-1-ynamide are also reported.
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Gold‐Catalyzed Oxidative Cyclizations of cis‐3‐En‐1‐ynes To Form Cyclopentenone Derivatives
Angewandte Chemie (International ed. in English), 2012Co-Authors: Sabyasachi Bhunia, Satish Ghorpade, Deepak B. Huple, Rai-shung LiuAbstract:the corresponding oxidative cyclizationremains undocumented. Herein, we report new gold-cata-lyzed oxidative cyclizations of cis-3-en-1-ynes to give cyclo-pentenone skeletons using 8-Methylquinoline oxide (Sche-me 1b). Notably, the mechanistic transformation of this C Hactivation is proven to proceed through a noncarbene route,thus excluding the intermediacy of the a-carbonyl carbeneA.
Alan J. Welch - One of the best experts on this subject based on the ideXlab platform.
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Pentafluorophenyl Complexes of Platinum Containing Intramolecular Pt···H Hydrogen Bridging Interactions. Crystal Structures of [NBu4][Pt(C6F5)3(8-hydroxyquinaldine)] and [NBu4][Pt(C6F5)3(8-Methylquinoline)]
Inorganic Chemistry, 1996Co-Authors: José María Casas, Larry R. Falvello, Juan Forniés, Antonio Martín, Alan J. WelchAbstract:Anionic complexes with the molecular formula [NBu4][Pt(C6F5)3L] (L = 8-hydroxyquinoline, C9H7NO, (1); 8-hydroxyquinaldine, C10H10NO, (2); 7,8-benzo[h]quinoline, C13H9N, (3); 8-Methylquinoline, C10H...
Baiquan Wang - One of the best experts on this subject based on the ideXlab platform.
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Ru(II)-catalyzed amidation reactions of 8-Methylquinolines with azides via C(sp(3))-H activation.
Chemical communications (Cambridge England), 2015Co-Authors: Bingxian Liu, Baiquan WangAbstract:Ru(II)-catalyzed amidation reactions of 8-Methylquinolines with azides have been developed. They are the first examples of [(p-cymene)RuCl2]2-catalyzed C(sp(3))-H bond intermolecular amidation reactions which give quinolin-8-ylmethanamines under mild reaction conditions in good yields.
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Rhodium(III)-Catalyzed Alkenylation Reactions of 8-Methylquinolines with Alkynes by C(sp3)—H Activation.
ChemInform, 2014Co-Authors: Bingxian Liu, Tao Zhou, Haibin Song, Baiquan WangAbstract:The first transition-metal catalyzed alkylation of the C(sp3)—H bond of 8-Methylquinolines with internal alkynes offers a convenient synthesis of 8-allylated quinolines.
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Rhodium(III)-Catalyzed Intermolecular Amidation with Azides via C(sp3)–H Functionalization
The Journal of organic chemistry, 2014Co-Authors: Nuancheng Wang, Haibin Song, Baiquan WangAbstract:The amidation reactions of 8-Methylquinolines with azides catalyzed by a cationic rhodium(III) complex proceed efficiently to give quinolin-8-ylmethanamine derivatives in good yields via C(sp3)–H bond activation under external oxidant-free conditions. A catalytically competent five-membered rhodacycle has been isolated and characterized, revealing a key intermediate in the catalytic cycle.
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Rhodium(III)-Catalyzed Alkenylation Reactions of 8-Methylquinolines with Alkynes by C(sp3)H Activation†
Angewandte Chemie (International ed. in English), 2014Co-Authors: Bingxian Liu, Tao Zhou, Haibin Song, Baiquan WangAbstract:The alkenylation reactions of 8-Methylquinolines with alkynes, catalyzed by [{Cp*RhCl2}2], proceeds efficiently to give 8-allylquinolines in good yields by C(sp3)H bond activation. These reactions are highly regio- and stereoselective. A catalytically competent five-membered rhodacycle has been structurally characterized, thus revealing a key intermediate in the catalytic cycle.
Jiannan Xiang - One of the best experts on this subject based on the ideXlab platform.
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gold catalyzed synthesis of 4 2 oxoalkoxy butyl methanesulfonates via ring opening of tetrahydrofuran
ChemInform, 2015Co-Authors: Wangyong Huang, Jiannan Xiang, Weimin HeAbstract:An unexpected ring-opening of THF through α-oxo gold carbene generated from terminal alkynes in the presence of 8-ethylquinoline N-oxide and MesOH under mild reaction conditions is presented.
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gold catalyzed synthesis of 4 2 oxoalkoxy butyl methanesulfonates via ring opening of tetrahydrofuran
Chemistry Letters, 2014Co-Authors: Wangyong Huang, Jiannan Xiang, Weimin HeAbstract:A variety of terminal alkynes were converted into the corresponding 4-(2-oxoalkoxy)butyl methanesulfonates via a gold-catalyzed intermolecular oxidation reaction using 8-ethylquinoline N-oxide as t...
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Straightforward and Highly Efficient Synthesis of α-Acetoxy Ketones through Gold-Catalyzed Intermolecular Oxidation of Terminal Alkynes
Synthesis, 2013Co-Authors: Zhiwu Liang, Dong Yan, Jiannan XiangAbstract:A variety of terminal alkynes were efficiently converted into the corresponding α-acetoxy ketones through gold-catalyzed intermolecular oxidation in the presence of 8-Methylquinoline 1-oxide as the oxidant. The reaction probably proceeds through an α-oxo gold carbene intermolecular O–H insertion.
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Electrophilicity of α-oxo gold carbene intermediates: halogen abstractions from halogenated solvents leading to the formation of chloro/bromomethyl ketones
Organic & biomolecular chemistry, 2012Co-Authors: Longyong Xie, Jiannan Xiang, Liming ZhangAbstract:α-Oxo gold carbenes generated via intermolecular oxidation of terminal alkynes are shown to be highly electrophilic and can effectively abstract halogen from halogenated solvents such as 1,2-dichloroethane or 1,2-dibromoethane. Chloro/bromomethyl ketones are prepared in moderate efficiencies in one step using Ph3PAuNTf2 as the catalyst and 8-Methylquinoline N-oxide as the oxidant.
José María Casas - One of the best experts on this subject based on the ideXlab platform.
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Pentafluorophenyl Complexes of Platinum Containing Intramolecular Pt···H Hydrogen Bridging Interactions. Crystal Structures of [NBu4][Pt(C6F5)3(8-hydroxyquinaldine)] and [NBu4][Pt(C6F5)3(8-Methylquinoline)]
Inorganic Chemistry, 1996Co-Authors: José María Casas, Larry R. Falvello, Juan Forniés, Antonio Martín, Alan J. WelchAbstract:Anionic complexes with the molecular formula [NBu4][Pt(C6F5)3L] (L = 8-hydroxyquinoline, C9H7NO, (1); 8-hydroxyquinaldine, C10H10NO, (2); 7,8-benzo[h]quinoline, C13H9N, (3); 8-Methylquinoline, C10H...
