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Marc Roger Couturier - One of the best experts on this subject based on the ideXlab platform.
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association of campylobacter upsaliensis with persistent bloody diarrhea
Journal of Clinical Microbiology, 2012Co-Authors: Brianne A Couturier, Devon C Hale, Marc Roger CouturierAbstract:n 83-year-old male presented to the emergency department(ED) with an acute history of severe bloody diarrhea. Hissymptoms began with nausea, vomiting, and Abdominal Cramp-ing, which he mistook for constipation. The patient took a singledose of laxative and shortly thereafter experienced numerous ep-isodesofprofusebloodydiarrheathatcontinuedforseveralhours.He did not have fevers, chills, or sweats. The patient was found byhis wife at home, collapsed in a chair, and was brought to the EDfor evaluation. The patient’s past medical history was significantfor irritable bowel syndrome but no history of bloody diarrhea orrectal bleeding. His social history revealed contact with his sister-in-law and two canine pets, all with bloody diarrhea. On arrival inthe ED, the patient’s physical examination was unremarkable;however, out of concern for a lower gastrointestinal bleed, thepatient was admitted for observation and further testing. Stoolstudies were negative for all gastrointestinal pathogens, including
Brianne A Couturier - One of the best experts on this subject based on the ideXlab platform.
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association of campylobacter upsaliensis with persistent bloody diarrhea
Journal of Clinical Microbiology, 2012Co-Authors: Brianne A Couturier, Devon C Hale, Marc Roger CouturierAbstract:n 83-year-old male presented to the emergency department(ED) with an acute history of severe bloody diarrhea. Hissymptoms began with nausea, vomiting, and Abdominal Cramp-ing, which he mistook for constipation. The patient took a singledose of laxative and shortly thereafter experienced numerous ep-isodesofprofusebloodydiarrheathatcontinuedforseveralhours.He did not have fevers, chills, or sweats. The patient was found byhis wife at home, collapsed in a chair, and was brought to the EDfor evaluation. The patient’s past medical history was significantfor irritable bowel syndrome but no history of bloody diarrhea orrectal bleeding. His social history revealed contact with his sister-in-law and two canine pets, all with bloody diarrhea. On arrival inthe ED, the patient’s physical examination was unremarkable;however, out of concern for a lower gastrointestinal bleed, thepatient was admitted for observation and further testing. Stoolstudies were negative for all gastrointestinal pathogens, including
S. L. Lightman - One of the best experts on this subject based on the ideXlab platform.
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Therapeutic response to somatostatin analogue, BIM 23014, in metastatic prostatic cancer
Clinical & Experimental Metastasis, 1992Co-Authors: H. Parmar, C. D. A. Charlton, R. H. Phillips, L. Edwards, J. L. Bejot, F. Thomas, S. L. LightmanAbstract:Metastatic prostate cancer is well known to respond to hormonal manipulations, but once progression occurs new treatment modalities are required. Specific and systemic antitumour therapy is preferable to local treatments such as radiotherapy in such patients. The finding that somatostain analogue, BIM 23014, inhibits prostatic tumour growth in animal models is of great interest. We treated 25 poor risk patients with progressive metastatic prostate cancer. Sixteen had also failed to respond to ‘total androgen blockade’. Two patients have achieved a partial remission, one of which is maintained at over 30 months, and three had stable disease for over 6 months. Side effects have consisted of mild diarrhoea and Abdominal Cramp in the first few days of treatment in a minority of the patients. These results are encouraging and further randomized studies are in progress.
Devon C Hale - One of the best experts on this subject based on the ideXlab platform.
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association of campylobacter upsaliensis with persistent bloody diarrhea
Journal of Clinical Microbiology, 2012Co-Authors: Brianne A Couturier, Devon C Hale, Marc Roger CouturierAbstract:n 83-year-old male presented to the emergency department(ED) with an acute history of severe bloody diarrhea. Hissymptoms began with nausea, vomiting, and Abdominal Cramp-ing, which he mistook for constipation. The patient took a singledose of laxative and shortly thereafter experienced numerous ep-isodesofprofusebloodydiarrheathatcontinuedforseveralhours.He did not have fevers, chills, or sweats. The patient was found byhis wife at home, collapsed in a chair, and was brought to the EDfor evaluation. The patient’s past medical history was significantfor irritable bowel syndrome but no history of bloody diarrhea orrectal bleeding. His social history revealed contact with his sister-in-law and two canine pets, all with bloody diarrhea. On arrival inthe ED, the patient’s physical examination was unremarkable;however, out of concern for a lower gastrointestinal bleed, thepatient was admitted for observation and further testing. Stoolstudies were negative for all gastrointestinal pathogens, including
A. Il Idrissi - One of the best experts on this subject based on the ideXlab platform.
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Toxicité aiguë et action analgésique des huiles essentielles de Nepeta atlantica Ball et Nepeta tuberosa L. ssp. reticulata (Desf.) Maire
Phytotherapie, 2004Co-Authors: Houssine Bouidida, S. Fkih-tetouani, Katim Alaoui, Yahia Cherrah, A. Il IdrissiAbstract::The essential oils of Nepeta tuberosa L. ssp. reticulata (Desf ) Maire and Nepeta atlantica Ball have been studied. The main and common constituent to both species is present rates respectively of 75 % and 50 %. It is identified as the stérioisomère 4aα, 7α, 7a b -nepetalactone and could be responsible for the essential oils toxicity at high doses, the DL50 value is 0.68 ± 0.07 ml/kg (680.1 ± 70.3 mg/kg) with limits of confidences [0.456-0.904] ml/g for Nepeta tuberosa L ssp. retuculata and 0,936 ± 0,015 ml/kg (936,7 ± 15,46 mg/kg), with limits of confidences [0,888 - 0,986] ml/kg for Nepeta atlantica . The essential oils of the studied species are all strong peripheral analgesic with an important protection against Abdominal Cramp 67.49 % and 62.53 % for 0.015 ml/kg IP respectively for Nepeta tuberosa L ssp. reticulata and Nepeta atlantica , wich rise up to 90.82 % and 84.53 % for 0.030 ml/kg IP. On the other hand power central analgesic activity morphin like appears to 0.030 ml/kg IP for the two species.Résumé:Les huiles essentielles de Nepeta tuberosa L. ssp. reticulata (Desf.) Maire et Nepeta atlantica Ball, ont été étudiées. Le constituant majoritaire est commun aux deux espèces à des taux respectivement de 75 % et 50 %. Il est identifié comme étant le stérioisomère 4aα, 7α, 7aβ-nepétalactone et pourrait être responsable de la toxicité à fortes doses de ces HE, les DL 50 évaluées étant de 0,680 ± 0,070 ml/kg (680,1 ± 70,3 mg/kg), avec des limites de confiance de [0,456-0,904] ml/kg pour Nepeta tuberosa L. ssp. reticulata et 0,936 ± 0,015 ml/kg (936,7 ± 15,46 mg/kg) avec des limites de confiance de [0,888 - 0,986] ml/kg pour Nepeta atlantica . Les huiles essentielles des espèces étudiées sont toutes deux fortement analgésiques périphériques avec un pouvoir de protection vis-à-vis des Crampes Abdominales important de 67,49 % et 62,53 % à 0,015ml/kg IP pour respectivement Nepeta tuberosa L. ssp. reticulata et Nepeta atlantica , atteignant 90,82 % et 84,53 % à 0,030 ml/kg IP. Par ailleurs, un pouvoir analgésique central morphine-like est enregistré à 0,030 ml/kg IP pour les deux espèces.