The Experts below are selected from a list of 234 Experts worldwide ranked by ideXlab platform
Dennis S Chi - One of the best experts on this subject based on the ideXlab platform.
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the effect of primary cytoreduction on outcomes of patients with figo stage iiic ovarian cancer stratified by the initial tumor burden in the upper abdomen cephalad to the greater omentum
Gynecologic Oncology, 2010Co-Authors: Oliver Zivanovic, Alexia Iasonos, Yukio Sonoda, Nadeem R Aburustum, Richard R Barakat, Camelia S Sima, William J Hoskins, Pavani R Pingle, Mario M Leitao, Dennis S ChiAbstract:Objective Our objective was to analyze the effect of surgical outcome on progression-free survival (PFS) and overall survival (OS) of patients with advanced ovarian carcinoma stratified by the initial presence and volume of upper Abdominal Disease cephalad to the greater omentum (UAD) found at the time of exploration.
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the impact of bulky upper Abdominal Disease cephalad to the greater omentum on surgical outcome for stage iiic epithelial ovarian fallopian tube and primary peritoneal cancer
Gynecologic Oncology, 2008Co-Authors: Oliver Zivanovic, Eric L Eisenhauer, Qin Zhou, Alexia Iasonos, Paul Sabbatini, Yukio Sonoda, Nadeem R Aburustum, Richard R Barakat, Dennis S ChiAbstract:Abstract Objective. To analyze the impact of bulky upper Abdominal Disease (UAD) cephalad to the greater omentum on surgical outcomes for patients with stage IIIC epithelial ovarian, fallopian tube, and primary peritoneal carcinoma. Methods. All patients with stage IIIC epithelial ovarian, fallopian tube, and primary peritoneal carcinoma who underwent primary cytoreductive surgery at our institution from 1989 to 2005 were eligible for the study. UAD cephalad to the greater omentum was defined as cancerous lesions involving the diaphragm, liver, porta hepatis, spleen, pancreas, stomach, and lesser sac. The study group was divided into three groups based on the presence and size of UAD cephalad to the greater omentum at the beginning of surgery—group 1, no Disease; group 2, ≤ 1 cm Disease; and group 3, bulky Disease > 1 cm. These three groups were further divided into two subsets based on the routine use of extensive upper Abdominal surgery after January 1, 2001. Standard statistical analyses were utilized. Results. We identified 490 patients who met study inclusion criteria. Their median age was 61 years (range, 25–88). UAD status was recorded in 474 patients as follows: group 1 (no UAD), 116 (24%); group 2 (≤ 1 cm UAD), 161 (34%); and group 3 (bulky UAD > 1 cm), 197 (42%). Bulky UAD was associated with ascites volume (P 500 ml, 54% had bulky UAD cephalad to the greater omentum, 37% had minimal UAD, and 9% had no evidence of UAD. Optimal surgical outcome (≤ 1 cm residual Disease) was achieved in 81%, 63%, and 39% of patients in groups 1, 2, and 3, respectively (P Conclusion. The upper abdomen cephalad to the greater omentum is frequently involved in patients with stage IIIC ovarian, tubal, and peritoneal carcinoma. This Disease site is significantly associated with large-volume ascites and suboptimal cytoreduction. Over the course of 17 years, however, the significant improvement in optimal cytoreduction rates has been most apparent in patients with bulky UAD. These findings emphasize the importance of comprehensive training, preparation, and referral when appropriate to centers that specialize in the surgical management of patients with advanced ovarian, tubal, and peritoneal carcinoma.
Oliver Zivanovic - One of the best experts on this subject based on the ideXlab platform.
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the effect of primary cytoreduction on outcomes of patients with figo stage iiic ovarian cancer stratified by the initial tumor burden in the upper abdomen cephalad to the greater omentum
Gynecologic Oncology, 2010Co-Authors: Oliver Zivanovic, Alexia Iasonos, Yukio Sonoda, Nadeem R Aburustum, Richard R Barakat, Camelia S Sima, William J Hoskins, Pavani R Pingle, Mario M Leitao, Dennis S ChiAbstract:Objective Our objective was to analyze the effect of surgical outcome on progression-free survival (PFS) and overall survival (OS) of patients with advanced ovarian carcinoma stratified by the initial presence and volume of upper Abdominal Disease cephalad to the greater omentum (UAD) found at the time of exploration.
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the impact of bulky upper Abdominal Disease cephalad to the greater omentum on surgical outcome for stage iiic epithelial ovarian fallopian tube and primary peritoneal cancer
Gynecologic Oncology, 2008Co-Authors: Oliver Zivanovic, Eric L Eisenhauer, Qin Zhou, Alexia Iasonos, Paul Sabbatini, Yukio Sonoda, Nadeem R Aburustum, Richard R Barakat, Dennis S ChiAbstract:Abstract Objective. To analyze the impact of bulky upper Abdominal Disease (UAD) cephalad to the greater omentum on surgical outcomes for patients with stage IIIC epithelial ovarian, fallopian tube, and primary peritoneal carcinoma. Methods. All patients with stage IIIC epithelial ovarian, fallopian tube, and primary peritoneal carcinoma who underwent primary cytoreductive surgery at our institution from 1989 to 2005 were eligible for the study. UAD cephalad to the greater omentum was defined as cancerous lesions involving the diaphragm, liver, porta hepatis, spleen, pancreas, stomach, and lesser sac. The study group was divided into three groups based on the presence and size of UAD cephalad to the greater omentum at the beginning of surgery—group 1, no Disease; group 2, ≤ 1 cm Disease; and group 3, bulky Disease > 1 cm. These three groups were further divided into two subsets based on the routine use of extensive upper Abdominal surgery after January 1, 2001. Standard statistical analyses were utilized. Results. We identified 490 patients who met study inclusion criteria. Their median age was 61 years (range, 25–88). UAD status was recorded in 474 patients as follows: group 1 (no UAD), 116 (24%); group 2 (≤ 1 cm UAD), 161 (34%); and group 3 (bulky UAD > 1 cm), 197 (42%). Bulky UAD was associated with ascites volume (P 500 ml, 54% had bulky UAD cephalad to the greater omentum, 37% had minimal UAD, and 9% had no evidence of UAD. Optimal surgical outcome (≤ 1 cm residual Disease) was achieved in 81%, 63%, and 39% of patients in groups 1, 2, and 3, respectively (P Conclusion. The upper abdomen cephalad to the greater omentum is frequently involved in patients with stage IIIC ovarian, tubal, and peritoneal carcinoma. This Disease site is significantly associated with large-volume ascites and suboptimal cytoreduction. Over the course of 17 years, however, the significant improvement in optimal cytoreduction rates has been most apparent in patients with bulky UAD. These findings emphasize the importance of comprehensive training, preparation, and referral when appropriate to centers that specialize in the surgical management of patients with advanced ovarian, tubal, and peritoneal carcinoma.
Richard R Barakat - One of the best experts on this subject based on the ideXlab platform.
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the effect of primary cytoreduction on outcomes of patients with figo stage iiic ovarian cancer stratified by the initial tumor burden in the upper abdomen cephalad to the greater omentum
Gynecologic Oncology, 2010Co-Authors: Oliver Zivanovic, Alexia Iasonos, Yukio Sonoda, Nadeem R Aburustum, Richard R Barakat, Camelia S Sima, William J Hoskins, Pavani R Pingle, Mario M Leitao, Dennis S ChiAbstract:Objective Our objective was to analyze the effect of surgical outcome on progression-free survival (PFS) and overall survival (OS) of patients with advanced ovarian carcinoma stratified by the initial presence and volume of upper Abdominal Disease cephalad to the greater omentum (UAD) found at the time of exploration.
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the impact of bulky upper Abdominal Disease cephalad to the greater omentum on surgical outcome for stage iiic epithelial ovarian fallopian tube and primary peritoneal cancer
Gynecologic Oncology, 2008Co-Authors: Oliver Zivanovic, Eric L Eisenhauer, Qin Zhou, Alexia Iasonos, Paul Sabbatini, Yukio Sonoda, Nadeem R Aburustum, Richard R Barakat, Dennis S ChiAbstract:Abstract Objective. To analyze the impact of bulky upper Abdominal Disease (UAD) cephalad to the greater omentum on surgical outcomes for patients with stage IIIC epithelial ovarian, fallopian tube, and primary peritoneal carcinoma. Methods. All patients with stage IIIC epithelial ovarian, fallopian tube, and primary peritoneal carcinoma who underwent primary cytoreductive surgery at our institution from 1989 to 2005 were eligible for the study. UAD cephalad to the greater omentum was defined as cancerous lesions involving the diaphragm, liver, porta hepatis, spleen, pancreas, stomach, and lesser sac. The study group was divided into three groups based on the presence and size of UAD cephalad to the greater omentum at the beginning of surgery—group 1, no Disease; group 2, ≤ 1 cm Disease; and group 3, bulky Disease > 1 cm. These three groups were further divided into two subsets based on the routine use of extensive upper Abdominal surgery after January 1, 2001. Standard statistical analyses were utilized. Results. We identified 490 patients who met study inclusion criteria. Their median age was 61 years (range, 25–88). UAD status was recorded in 474 patients as follows: group 1 (no UAD), 116 (24%); group 2 (≤ 1 cm UAD), 161 (34%); and group 3 (bulky UAD > 1 cm), 197 (42%). Bulky UAD was associated with ascites volume (P 500 ml, 54% had bulky UAD cephalad to the greater omentum, 37% had minimal UAD, and 9% had no evidence of UAD. Optimal surgical outcome (≤ 1 cm residual Disease) was achieved in 81%, 63%, and 39% of patients in groups 1, 2, and 3, respectively (P Conclusion. The upper abdomen cephalad to the greater omentum is frequently involved in patients with stage IIIC ovarian, tubal, and peritoneal carcinoma. This Disease site is significantly associated with large-volume ascites and suboptimal cytoreduction. Over the course of 17 years, however, the significant improvement in optimal cytoreduction rates has been most apparent in patients with bulky UAD. These findings emphasize the importance of comprehensive training, preparation, and referral when appropriate to centers that specialize in the surgical management of patients with advanced ovarian, tubal, and peritoneal carcinoma.
Nadeem R Aburustum - One of the best experts on this subject based on the ideXlab platform.
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the effect of primary cytoreduction on outcomes of patients with figo stage iiic ovarian cancer stratified by the initial tumor burden in the upper abdomen cephalad to the greater omentum
Gynecologic Oncology, 2010Co-Authors: Oliver Zivanovic, Alexia Iasonos, Yukio Sonoda, Nadeem R Aburustum, Richard R Barakat, Camelia S Sima, William J Hoskins, Pavani R Pingle, Mario M Leitao, Dennis S ChiAbstract:Objective Our objective was to analyze the effect of surgical outcome on progression-free survival (PFS) and overall survival (OS) of patients with advanced ovarian carcinoma stratified by the initial presence and volume of upper Abdominal Disease cephalad to the greater omentum (UAD) found at the time of exploration.
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the impact of bulky upper Abdominal Disease cephalad to the greater omentum on surgical outcome for stage iiic epithelial ovarian fallopian tube and primary peritoneal cancer
Gynecologic Oncology, 2008Co-Authors: Oliver Zivanovic, Eric L Eisenhauer, Qin Zhou, Alexia Iasonos, Paul Sabbatini, Yukio Sonoda, Nadeem R Aburustum, Richard R Barakat, Dennis S ChiAbstract:Abstract Objective. To analyze the impact of bulky upper Abdominal Disease (UAD) cephalad to the greater omentum on surgical outcomes for patients with stage IIIC epithelial ovarian, fallopian tube, and primary peritoneal carcinoma. Methods. All patients with stage IIIC epithelial ovarian, fallopian tube, and primary peritoneal carcinoma who underwent primary cytoreductive surgery at our institution from 1989 to 2005 were eligible for the study. UAD cephalad to the greater omentum was defined as cancerous lesions involving the diaphragm, liver, porta hepatis, spleen, pancreas, stomach, and lesser sac. The study group was divided into three groups based on the presence and size of UAD cephalad to the greater omentum at the beginning of surgery—group 1, no Disease; group 2, ≤ 1 cm Disease; and group 3, bulky Disease > 1 cm. These three groups were further divided into two subsets based on the routine use of extensive upper Abdominal surgery after January 1, 2001. Standard statistical analyses were utilized. Results. We identified 490 patients who met study inclusion criteria. Their median age was 61 years (range, 25–88). UAD status was recorded in 474 patients as follows: group 1 (no UAD), 116 (24%); group 2 (≤ 1 cm UAD), 161 (34%); and group 3 (bulky UAD > 1 cm), 197 (42%). Bulky UAD was associated with ascites volume (P 500 ml, 54% had bulky UAD cephalad to the greater omentum, 37% had minimal UAD, and 9% had no evidence of UAD. Optimal surgical outcome (≤ 1 cm residual Disease) was achieved in 81%, 63%, and 39% of patients in groups 1, 2, and 3, respectively (P Conclusion. The upper abdomen cephalad to the greater omentum is frequently involved in patients with stage IIIC ovarian, tubal, and peritoneal carcinoma. This Disease site is significantly associated with large-volume ascites and suboptimal cytoreduction. Over the course of 17 years, however, the significant improvement in optimal cytoreduction rates has been most apparent in patients with bulky UAD. These findings emphasize the importance of comprehensive training, preparation, and referral when appropriate to centers that specialize in the surgical management of patients with advanced ovarian, tubal, and peritoneal carcinoma.
Yukio Sonoda - One of the best experts on this subject based on the ideXlab platform.
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the effect of primary cytoreduction on outcomes of patients with figo stage iiic ovarian cancer stratified by the initial tumor burden in the upper abdomen cephalad to the greater omentum
Gynecologic Oncology, 2010Co-Authors: Oliver Zivanovic, Alexia Iasonos, Yukio Sonoda, Nadeem R Aburustum, Richard R Barakat, Camelia S Sima, William J Hoskins, Pavani R Pingle, Mario M Leitao, Dennis S ChiAbstract:Objective Our objective was to analyze the effect of surgical outcome on progression-free survival (PFS) and overall survival (OS) of patients with advanced ovarian carcinoma stratified by the initial presence and volume of upper Abdominal Disease cephalad to the greater omentum (UAD) found at the time of exploration.
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the impact of bulky upper Abdominal Disease cephalad to the greater omentum on surgical outcome for stage iiic epithelial ovarian fallopian tube and primary peritoneal cancer
Gynecologic Oncology, 2008Co-Authors: Oliver Zivanovic, Eric L Eisenhauer, Qin Zhou, Alexia Iasonos, Paul Sabbatini, Yukio Sonoda, Nadeem R Aburustum, Richard R Barakat, Dennis S ChiAbstract:Abstract Objective. To analyze the impact of bulky upper Abdominal Disease (UAD) cephalad to the greater omentum on surgical outcomes for patients with stage IIIC epithelial ovarian, fallopian tube, and primary peritoneal carcinoma. Methods. All patients with stage IIIC epithelial ovarian, fallopian tube, and primary peritoneal carcinoma who underwent primary cytoreductive surgery at our institution from 1989 to 2005 were eligible for the study. UAD cephalad to the greater omentum was defined as cancerous lesions involving the diaphragm, liver, porta hepatis, spleen, pancreas, stomach, and lesser sac. The study group was divided into three groups based on the presence and size of UAD cephalad to the greater omentum at the beginning of surgery—group 1, no Disease; group 2, ≤ 1 cm Disease; and group 3, bulky Disease > 1 cm. These three groups were further divided into two subsets based on the routine use of extensive upper Abdominal surgery after January 1, 2001. Standard statistical analyses were utilized. Results. We identified 490 patients who met study inclusion criteria. Their median age was 61 years (range, 25–88). UAD status was recorded in 474 patients as follows: group 1 (no UAD), 116 (24%); group 2 (≤ 1 cm UAD), 161 (34%); and group 3 (bulky UAD > 1 cm), 197 (42%). Bulky UAD was associated with ascites volume (P 500 ml, 54% had bulky UAD cephalad to the greater omentum, 37% had minimal UAD, and 9% had no evidence of UAD. Optimal surgical outcome (≤ 1 cm residual Disease) was achieved in 81%, 63%, and 39% of patients in groups 1, 2, and 3, respectively (P Conclusion. The upper abdomen cephalad to the greater omentum is frequently involved in patients with stage IIIC ovarian, tubal, and peritoneal carcinoma. This Disease site is significantly associated with large-volume ascites and suboptimal cytoreduction. Over the course of 17 years, however, the significant improvement in optimal cytoreduction rates has been most apparent in patients with bulky UAD. These findings emphasize the importance of comprehensive training, preparation, and referral when appropriate to centers that specialize in the surgical management of patients with advanced ovarian, tubal, and peritoneal carcinoma.
