The Experts below are selected from a list of 273 Experts worldwide ranked by ideXlab platform
Eric T Poehlman - One of the best experts on this subject based on the ideXlab platform.
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Effect of menopausal status on body composition and Abdominal Fat distribution.
International Journal of Obesity, 2000Co-Authors: Michael J Toth, Andre Tchernof, Cynthia K Sites, Eric T PoehlmanAbstract:OBJECTIVE: Preliminary studies suggest that the menopause transition is associated with deleterious changes in body composition and Abdominal Fat distribution. Limitations of the methodology used in these studies, however, render their conclusions controversial. Thus, the present study used radiologic imaging techniques to examine the effect of menopausal status on body composition and Abdominal Fat distribution. DESIGN: Cross-sectional. SUBJECTS: Fifty-three healthy, middle-aged, premenopausal women (mean ± SD; 47 ± 3 y) and 28 early-postmenopausal women (51 ± 4y). MEASUREMENTS: Total and regional body composition by dual energy X-ray absorptiometry and Abdominal Fat distribution by computed tomography. RESULTS: No differences in total body Fat-free mass or appendicular skeletal muscle mass were noted between groups. In contrast, total body Fat mass was 28% higher (23 ± 7 vs 18 ± 7 kg) and percentage Fat 17% higher (35 ± 6 vs 30 ± 9%; both P < 0.01) in postmenopausal women compared with premenopausal women. Postmenopausal women had a 49% greater intra-Abdominal (88 ± 32 vs 59 ± 32 cm 2 ; P
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effect of menopausal status on body composition and Abdominal Fat distribution
International Journal of Obesity, 2000Co-Authors: Michael J Toth, Andre Tchernof, Cynthia K Sites, Eric T PoehlmanAbstract:OBJECTIVE: Preliminary studies suggest that the menopause transition is associated with deleterious changes in body composition and Abdominal Fat distribution. Limitations of the methodology used in these studies, however, render their conclusions controversial. Thus, the present study used radiologic imaging techniques to examine the effect of menopausal status on body composition and Abdominal Fat distribution. DESIGN: Cross-sectional. SUBJECTS: Fifty-three healthy, middle-aged, premenopausal women (mean±SD; 47±3 y) and 28 early-postmenopausal women (51±4 y). MEASUREMENTS: Total and regional body composition by dual energy X-ray absorptiometry and Abdominal Fat distribution by computed tomography. RESULTS: No differences in total body Fat-free mass or appendicular skeletal muscle mass were noted between groups. In contrast, total body Fat mass was 28% higher (23±7 vs 18±7 kg) and percentage Fat 17% higher (35±6 vs 30±9%; both P<0.01) in postmenopausal women compared with premenopausal women. Postmenopausal women had a 49% greater intra-Abdominal (88±32 vs 59±32 cm2; P<0.01) and a 22% greater Abdominal subcutaneous Fat area (277±93 vs 227±108 cm2; P<0.05) compared to premenopausal women. The menopause-related difference in intra-Abdominal Fat persisted (P<0.05) after statistical adjustment for age and total body Fat mass, whereas no difference in Abdominal subcutaneous Fat was noted. A similar pattern of differences in total and Abdominal adiposity was noted in sub-samples of pre- and postmenopausal women matched for age or Fat mass. CONCLUSION: Our data suggest that early-postmenopausal status is associated with a preferential increase in intra-Abdominal Fat that is independent of age and total body Fat mass.
Michael J Toth - One of the best experts on this subject based on the ideXlab platform.
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Effect of menopausal status on body composition and Abdominal Fat distribution.
International Journal of Obesity, 2000Co-Authors: Michael J Toth, Andre Tchernof, Cynthia K Sites, Eric T PoehlmanAbstract:OBJECTIVE: Preliminary studies suggest that the menopause transition is associated with deleterious changes in body composition and Abdominal Fat distribution. Limitations of the methodology used in these studies, however, render their conclusions controversial. Thus, the present study used radiologic imaging techniques to examine the effect of menopausal status on body composition and Abdominal Fat distribution. DESIGN: Cross-sectional. SUBJECTS: Fifty-three healthy, middle-aged, premenopausal women (mean ± SD; 47 ± 3 y) and 28 early-postmenopausal women (51 ± 4y). MEASUREMENTS: Total and regional body composition by dual energy X-ray absorptiometry and Abdominal Fat distribution by computed tomography. RESULTS: No differences in total body Fat-free mass or appendicular skeletal muscle mass were noted between groups. In contrast, total body Fat mass was 28% higher (23 ± 7 vs 18 ± 7 kg) and percentage Fat 17% higher (35 ± 6 vs 30 ± 9%; both P < 0.01) in postmenopausal women compared with premenopausal women. Postmenopausal women had a 49% greater intra-Abdominal (88 ± 32 vs 59 ± 32 cm 2 ; P
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effect of menopausal status on body composition and Abdominal Fat distribution
International Journal of Obesity, 2000Co-Authors: Michael J Toth, Andre Tchernof, Cynthia K Sites, Eric T PoehlmanAbstract:OBJECTIVE: Preliminary studies suggest that the menopause transition is associated with deleterious changes in body composition and Abdominal Fat distribution. Limitations of the methodology used in these studies, however, render their conclusions controversial. Thus, the present study used radiologic imaging techniques to examine the effect of menopausal status on body composition and Abdominal Fat distribution. DESIGN: Cross-sectional. SUBJECTS: Fifty-three healthy, middle-aged, premenopausal women (mean±SD; 47±3 y) and 28 early-postmenopausal women (51±4 y). MEASUREMENTS: Total and regional body composition by dual energy X-ray absorptiometry and Abdominal Fat distribution by computed tomography. RESULTS: No differences in total body Fat-free mass or appendicular skeletal muscle mass were noted between groups. In contrast, total body Fat mass was 28% higher (23±7 vs 18±7 kg) and percentage Fat 17% higher (35±6 vs 30±9%; both P<0.01) in postmenopausal women compared with premenopausal women. Postmenopausal women had a 49% greater intra-Abdominal (88±32 vs 59±32 cm2; P<0.01) and a 22% greater Abdominal subcutaneous Fat area (277±93 vs 227±108 cm2; P<0.05) compared to premenopausal women. The menopause-related difference in intra-Abdominal Fat persisted (P<0.05) after statistical adjustment for age and total body Fat mass, whereas no difference in Abdominal subcutaneous Fat was noted. A similar pattern of differences in total and Abdominal adiposity was noted in sub-samples of pre- and postmenopausal women matched for age or Fat mass. CONCLUSION: Our data suggest that early-postmenopausal status is associated with a preferential increase in intra-Abdominal Fat that is independent of age and total body Fat mass.
Andre Tchernof - One of the best experts on this subject based on the ideXlab platform.
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Effect of menopausal status on body composition and Abdominal Fat distribution.
International Journal of Obesity, 2000Co-Authors: Michael J Toth, Andre Tchernof, Cynthia K Sites, Eric T PoehlmanAbstract:OBJECTIVE: Preliminary studies suggest that the menopause transition is associated with deleterious changes in body composition and Abdominal Fat distribution. Limitations of the methodology used in these studies, however, render their conclusions controversial. Thus, the present study used radiologic imaging techniques to examine the effect of menopausal status on body composition and Abdominal Fat distribution. DESIGN: Cross-sectional. SUBJECTS: Fifty-three healthy, middle-aged, premenopausal women (mean ± SD; 47 ± 3 y) and 28 early-postmenopausal women (51 ± 4y). MEASUREMENTS: Total and regional body composition by dual energy X-ray absorptiometry and Abdominal Fat distribution by computed tomography. RESULTS: No differences in total body Fat-free mass or appendicular skeletal muscle mass were noted between groups. In contrast, total body Fat mass was 28% higher (23 ± 7 vs 18 ± 7 kg) and percentage Fat 17% higher (35 ± 6 vs 30 ± 9%; both P < 0.01) in postmenopausal women compared with premenopausal women. Postmenopausal women had a 49% greater intra-Abdominal (88 ± 32 vs 59 ± 32 cm 2 ; P
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effect of menopausal status on body composition and Abdominal Fat distribution
International Journal of Obesity, 2000Co-Authors: Michael J Toth, Andre Tchernof, Cynthia K Sites, Eric T PoehlmanAbstract:OBJECTIVE: Preliminary studies suggest that the menopause transition is associated with deleterious changes in body composition and Abdominal Fat distribution. Limitations of the methodology used in these studies, however, render their conclusions controversial. Thus, the present study used radiologic imaging techniques to examine the effect of menopausal status on body composition and Abdominal Fat distribution. DESIGN: Cross-sectional. SUBJECTS: Fifty-three healthy, middle-aged, premenopausal women (mean±SD; 47±3 y) and 28 early-postmenopausal women (51±4 y). MEASUREMENTS: Total and regional body composition by dual energy X-ray absorptiometry and Abdominal Fat distribution by computed tomography. RESULTS: No differences in total body Fat-free mass or appendicular skeletal muscle mass were noted between groups. In contrast, total body Fat mass was 28% higher (23±7 vs 18±7 kg) and percentage Fat 17% higher (35±6 vs 30±9%; both P<0.01) in postmenopausal women compared with premenopausal women. Postmenopausal women had a 49% greater intra-Abdominal (88±32 vs 59±32 cm2; P<0.01) and a 22% greater Abdominal subcutaneous Fat area (277±93 vs 227±108 cm2; P<0.05) compared to premenopausal women. The menopause-related difference in intra-Abdominal Fat persisted (P<0.05) after statistical adjustment for age and total body Fat mass, whereas no difference in Abdominal subcutaneous Fat was noted. A similar pattern of differences in total and Abdominal adiposity was noted in sub-samples of pre- and postmenopausal women matched for age or Fat mass. CONCLUSION: Our data suggest that early-postmenopausal status is associated with a preferential increase in intra-Abdominal Fat that is independent of age and total body Fat mass.
Cynthia K Sites - One of the best experts on this subject based on the ideXlab platform.
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Effect of menopausal status on body composition and Abdominal Fat distribution.
International Journal of Obesity, 2000Co-Authors: Michael J Toth, Andre Tchernof, Cynthia K Sites, Eric T PoehlmanAbstract:OBJECTIVE: Preliminary studies suggest that the menopause transition is associated with deleterious changes in body composition and Abdominal Fat distribution. Limitations of the methodology used in these studies, however, render their conclusions controversial. Thus, the present study used radiologic imaging techniques to examine the effect of menopausal status on body composition and Abdominal Fat distribution. DESIGN: Cross-sectional. SUBJECTS: Fifty-three healthy, middle-aged, premenopausal women (mean ± SD; 47 ± 3 y) and 28 early-postmenopausal women (51 ± 4y). MEASUREMENTS: Total and regional body composition by dual energy X-ray absorptiometry and Abdominal Fat distribution by computed tomography. RESULTS: No differences in total body Fat-free mass or appendicular skeletal muscle mass were noted between groups. In contrast, total body Fat mass was 28% higher (23 ± 7 vs 18 ± 7 kg) and percentage Fat 17% higher (35 ± 6 vs 30 ± 9%; both P < 0.01) in postmenopausal women compared with premenopausal women. Postmenopausal women had a 49% greater intra-Abdominal (88 ± 32 vs 59 ± 32 cm 2 ; P
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effect of menopausal status on body composition and Abdominal Fat distribution
International Journal of Obesity, 2000Co-Authors: Michael J Toth, Andre Tchernof, Cynthia K Sites, Eric T PoehlmanAbstract:OBJECTIVE: Preliminary studies suggest that the menopause transition is associated with deleterious changes in body composition and Abdominal Fat distribution. Limitations of the methodology used in these studies, however, render their conclusions controversial. Thus, the present study used radiologic imaging techniques to examine the effect of menopausal status on body composition and Abdominal Fat distribution. DESIGN: Cross-sectional. SUBJECTS: Fifty-three healthy, middle-aged, premenopausal women (mean±SD; 47±3 y) and 28 early-postmenopausal women (51±4 y). MEASUREMENTS: Total and regional body composition by dual energy X-ray absorptiometry and Abdominal Fat distribution by computed tomography. RESULTS: No differences in total body Fat-free mass or appendicular skeletal muscle mass were noted between groups. In contrast, total body Fat mass was 28% higher (23±7 vs 18±7 kg) and percentage Fat 17% higher (35±6 vs 30±9%; both P<0.01) in postmenopausal women compared with premenopausal women. Postmenopausal women had a 49% greater intra-Abdominal (88±32 vs 59±32 cm2; P<0.01) and a 22% greater Abdominal subcutaneous Fat area (277±93 vs 227±108 cm2; P<0.05) compared to premenopausal women. The menopause-related difference in intra-Abdominal Fat persisted (P<0.05) after statistical adjustment for age and total body Fat mass, whereas no difference in Abdominal subcutaneous Fat was noted. A similar pattern of differences in total and Abdominal adiposity was noted in sub-samples of pre- and postmenopausal women matched for age or Fat mass. CONCLUSION: Our data suggest that early-postmenopausal status is associated with a preferential increase in intra-Abdominal Fat that is independent of age and total body Fat mass.
K Ishikawa - One of the best experts on this subject based on the ideXlab platform.
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Intra-Abdominal Fat, Lipid Metabolism and Insulin Resistance in Coronary Artery Disease
Hypertension Research, 1996Co-Authors: T Kawamoto, K IshikawaAbstract:To investigate the metabolic and atherogenic effect of intra-Abdominal Fat accumulation, we examined correlation between variables of lipid and glucose and the Fat distribution of abdominen by using computed tomography. Subjects were 292 of male and 161 of female who underwent coronary angiography. Intra-Abdominal Fat area was correlated with insulin concentration at 120min in oral glucose tolerance tests and triglyceride level in male, on the other hand, in female were HDL-cholesterol level, apolipoprotein B, glucose area under curve and insulin concentration at 60 and 120min. In an aspect of atherogenic effect of Intra-Abdominal Fat, it was not atherogenic in isolated state in male, but atherogenic in diabetic female. Intra-Abdominal Fat was accompanied with hypertension and mid-band, which appeared between alpha and beta band in polyacrylamide diskgel electrophoresis. Cluster of Intra-Abdominal Fat accumulation, hypertension and mid-band was atherogenic in male, in which insulin resistance play an important role in the coronary artery disease. On the contrary, Intra-Abdominal Fat accumulation accompanied with exacerbation of glucose tolerance, hypertensive and high level of apolipoprotein B in female. We concluded that visceral Fat accumulation was a generator of metabolic syndrome X in male and was a progression factor for diabetes, hypertensive and high apolipoprotein B level in female. (Hypertens Res 1996; 19 Suppl. I: S69-S74)
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Intra-Abdominal Fat, lipid metabolism and insulin resistance in coronary artery disease.
Hypertension research : official journal of the Japanese Society of Hypertension, 1996Co-Authors: T Kawamoto, K IshikawaAbstract:To investigate the metabolic and atherogenic effect of intra-Abdominal Fat accumulation, we examined correlation between variables of lipid and glucose and the Fat distribution of abdominen by using computed tomography. Subjects were 292 of male and 161 of female who underwent coronary angiography. Intra-Abdominal Fat area was correlated with insulin concentration at 120 min in oral glucose tolerance tests and triglyceride level in male, on the other hand, in female were HDL-cholesterol level, apolipoprotein B, glucose area under curve and insulin concentration at 60 and 120 min. In an aspect of atherogenic effect of intra-Abdominal Fat, it was not atherogenic in isolated state in male, but atherogenic in diabetic female. Intra-Abdominal Fat was accompanied with hypertension and mid-band, which appeared between alpha and beta band in polyacrylamide diskgel electrophoresis. Cluster of intra-Abdominal Fat accumulation, hypertension and mid-band was atherogenic in male, in which insulin resistance play an important role in the coronary artery disease. On the contrary, intra-Abdominal Fat accumulation accompanied with exacerbation of glucose tolerance, hypertensive and high level of apolipoprotein B in female. We concluded that visceral Fat accumulation was a generator of metabolic syndrome X in male and was a progression factor for diabetes, hypertensive and high apolipoprotein B level in female.
