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Yoshihiko Maehara – One of the best experts on this subject based on the ideXlab platform.
subcuticular Absorbable Suture with subcutaneous drainage system prevents incisional ssi after hepatectomy for hepatocellular carcinomaWorld Journal of Surgery, 2012Co-Authors: Eiji Tsujita, Yo Ichi Yamashita, Kazuki Takeishi, Ayumi Matsuyama, Shin Ichi Tsutsui, Hiroyuki Matsuda, Akinobu Taketomi, Ken Shirabe, Teruyoshi Ishida, Yoshihiko MaeharaAbstract:
The effectiveness of subcuticular Absorbable Suture with subcutaneous drainage to decrease the risk of postoperative incisional surgical site infection (SSI) in hepatocellular carcinoma (HCC) patients was evaluated.
Mark Walton – One of the best experts on this subject based on the ideXlab platform.
nonAbsorbable versus Absorbable Suture anchors for open bankart repair a prospective randomized comparisonAmerican Journal of Sports Medicine, 1999Co-Authors: Winston J Warme, Robert A Arciero, Felix H Savoie, John M Uhorchak, Mark WaltonAbstract:
Suture anchors facilitate the surgical repair of capsuloligamentous structures to bone. BioAbsorbable Suture anchors, which obviate potential pitfalls in the periarticular use of permanent implants, have recently become available. We randomly assigned 40 patients to undergo modified Bankart shoulder repairs with either nonAbsorbable or Absorbable Suture anchors. The patients had a history of recurrent traumatic anterior instability that had not improved with nonoperative management. The average patient age was 22 years (range, 17 to 46), and the average preoperative Rowe score was 47 points in the nonAbsorbable anchor group and 47 points in the Absorbable anchor group. Average postoperative Rowe scores were 96 and 93 points, respectively. There was one failed result in the nonAbsorbable anchor group and two in the Absorbable anchor group. No statistically significant subjective or objective differences were found at an average of 25 months postoperatively. Our results reveal that, in this application, bioAbsorbable Suture anchors are a viable option for the repair of soft tissue to bone.
George T. Rodeheaver – One of the best experts on this subject based on the ideXlab platform.
the influence of Absorbable subcuticular staples continuous subcuticular Absorbable Suture and percutaneous metal skin staples on infection in contaminated woundsJournal of Long-term Effects of Medical Implants, 2012Co-Authors: Angela Pinerosfernandez, Lisa S Salopek, Pamela F Rodeheaver, George T. RodeheaverAbstract:
Wound infection is a threatening, troublesome, and costly complication contributing to increased mortality and morbidity. The methods and materials used to close a wound significantly influence the quality of the repair process and the risk of surgical site infection. Six pigs were used to evaluate the influence of four separate skin-closure modalities on the potentiation of infection in contaminated wounds. Full-thickness skin wounds on the abdomen were contaminated with S. aureus and then closed with one of four devices: a novel Absorbable staple (InsorbTM) placed in the subcuticular tissue; a braided Absorbable Suture (VicrylTM); a monofilament Absorbable Suture (MonocrylTM); percutaneous metal staples. Wound infection was assessed 7 days after closure by clinical signs and quantitative bacterial swabs. InsorbTM staples had significantly lower infection rates than continuous VicrylTM (39% vs. 100%, p=0.002) or MonocrylTM Suture (39% vs. 89%, p=0.014). The InsorbTM subcuticular staple and the metal percutaneous skin staple were statistically equivalent in wound infection rate and parameters of inflammation. The combined data for both interrupted staple modalities documented less inflammation compared to the combined data for continuous Sutures. These lower levels of inflammatory metrics were statistically significant for edema (p=0.018), gauze exudate observed (p=0.007) and purulent exudate in wound (p<0.0001). In conclusion, InsorbTM staples were shown to be an acceptable choice for the closure of contaminated wounds because they had a significantly lower incidence of wound infection and inflammation when compared to continuous intradermal Suture.
caprosyn another major advance in synthetic monofilament Absorbable SutureJournal of Long-term Effects of Medical Implants, 2004Co-Authors: Angela Pinerosfernandez, Richard F Edlich, David B Drake, Pamela Rodeheaver, Deborah L Moody, George T. RodeheaverAbstract:
CAPROSYN* Suture is the latest innovation in monofilament synthetic Suture. This Suture is prepared from POLYGLYTONE*6211, a synthetic polyester composed of glycolide, caprolactone, trimethylene carbonate, and lactide. The purpose of this study was to compare the biomechanical performance of CAPROSYN* Suture to that of CHROMIC GUT Suture. The biomechanical performance studies included quantitative measurements of wound security, strength loss, mass loss, potentiation of infection, tissue drag, knot security, knot rundown, as well as Suture stiffness. Both CAPROSYN* and CHROMIC GUT Sutures provided comparable resistance to wound disruption. Prior to implantation, Suture loops of CAPROSYN* had a significantly greater mean breaking strength than Suture loops of CHROMIC GUT. Three weeks after implantation of these Absorbable Suture loops, the Sutures had no appreciable strength. The rate of loss of Suture mass of these two Sutures was similar. As expected, CHROMIC GUT Sutures potentiated significantly more infection than did the CAPROSYN* Sutures. The handling properties of the CAPROSYN* Sutures were far superior to those of the CHROMIC GUT Sutures. The smooth surface of the CAPROSYN* Sutures encountered lower drag forces than did the CHROMIC GUT Sutures. Furthermore, it was much easier to reposition the CAPROSYN* knotted Sutures than the knotted CHROMIC GUT Sutures. In the case of CHROMIC GUT Sutures, it was not possible to reposition a two-throw granny knot. These biomechanical performance studies demonstrated the superior performance of synthetic CAPROSYN* Sutures compared to CHROMIC GUT Sutures and provide compelling evidence of why CAPROSYN* Sutures are an excellent alternative to CHROMIC GUT Sutures.
Biomechanical and clinical performance of a new synthetic monofilament Absorbable Suture.Journal of Long-term Effects of Medical Implants, 1996Co-Authors: George T. Rodeheaver, Beltran Ka, Colleen W. Green, Brent C. Faulkner, Brendon M. Stiles, Stanimir Gw, Traeland H, Fried Gm, Brown Hc, Richard F EdlichAbstract:
: The clinical and mechanical performance of a new, monofilament, synthetic Absorbable Suture (Biosyn) was evaluated and compared to that of a braided synthetic Absorbable Suture (Vicryl). The monofilament synthetic Absorbable Suture was significantly stronger than the braided synthetic Absorbable Suture over the 4 weeks of implantation. In addition, the monofilament Suture potentiated less bacterial infection than did the braided Suture. The handling characteristics of the monofilament Suture were superior to the braided Suture because the monofilament Suture required fewer throws to achieve knot security, encountered lower drag forces in fascia and colon, and had a greater double-wrapped first-throw knot security. Evaluated independently in clinical settings, the monofilament Sutures were found to have excellent strength, first-throw hold, knot security, passage through tissue, knot repositioning, and ease of handling.