The Experts below are selected from a list of 372 Experts worldwide ranked by ideXlab platform
Amos Buchner - One of the best experts on this subject based on the ideXlab platform.
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warty dyskeratoma focal Acantholytic Dyskeratosis an update on a rare oral lesion
Journal of Oral Pathology & Medicine, 2012Co-Authors: Irit Allon, Amos BuchnerAbstract:J Oral Pathol Med (2012) 41: 261–267 Background: Warty dyskeratoma (WD) is an uncommon lesion of the skin that is considered to be associated with the pilosebaceous apparatus. Histologically similar lesions have been described in the oral region mainly by case reports and under the terms ‘WD’ or ‘focal Acantholytic Dyskeratosis (FAD)’. Owing to the paucity of reports, many aspects of the oral lesions remain unclear. The purpose of this study is to report a new case in an extremely rare location, the buccal mucosa, and to present a comprehensive updated review and analysis of the literature. Methods: We reviewed all cases of oral lesions that were diagnosed as WD and FAD and analyzed them according to their clinical and pathologic features. Results: The search yielded only 41 cases. The lesions usually appeared as asymptomatic, solitary, white nodules, papules, or patches on bone-bound mucosa. They occasionally had a rough surface and depressed center. The lesions were most common in the fifth to seventh decades. Use of tobacco appeared to be the most prevalent predisposing factor. The histopathological differential diagnosis of the lesion included Acantholytic squamous cell carcinoma, keratoacanthoma, and Darier’s disease. Conclusion: Warty dyskeratoma/FAD are uncommon oral lesions which are not encountered in the daily practice of oral pathologists. The absence of an association of oral lesions with the pilosebaceous apparatus suggests that they are probably distinctly different from cutaneous ones. As such, we suggest the histologic term isolated FAD for oral lesions, rather than WD.
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Warty dyskeratoma/focal Acantholytic Dyskeratosis--an update on a rare oral lesion.
Journal of Oral Pathology & Medicine, 2011Co-Authors: Irit Allon, Amos BuchnerAbstract:J Oral Pathol Med (2012) 41: 261–267 Background: Warty dyskeratoma (WD) is an uncommon lesion of the skin that is considered to be associated with the pilosebaceous apparatus. Histologically similar lesions have been described in the oral region mainly by case reports and under the terms ‘WD’ or ‘focal Acantholytic Dyskeratosis (FAD)’. Owing to the paucity of reports, many aspects of the oral lesions remain unclear. The purpose of this study is to report a new case in an extremely rare location, the buccal mucosa, and to present a comprehensive updated review and analysis of the literature. Methods: We reviewed all cases of oral lesions that were diagnosed as WD and FAD and analyzed them according to their clinical and pathologic features. Results: The search yielded only 41 cases. The lesions usually appeared as asymptomatic, solitary, white nodules, papules, or patches on bone-bound mucosa. They occasionally had a rough surface and depressed center. The lesions were most common in the fifth to seventh decades. Use of tobacco appeared to be the most prevalent predisposing factor. The histopathological differential diagnosis of the lesion included Acantholytic squamous cell carcinoma, keratoacanthoma, and Darier’s disease. Conclusion: Warty dyskeratoma/FAD are uncommon oral lesions which are not encountered in the daily practice of oral pathologists. The absence of an association of oral lesions with the pilosebaceous apparatus suggests that they are probably distinctly different from cutaneous ones. As such, we suggest the histologic term isolated FAD for oral lesions, rather than WD.
Sanz A Trelles - One of the best experts on this subject based on the ideXlab platform.
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pityriasis rubra pilaris with focal Acantholytic Dyskeratosis during treatment with imiquimod 5 cream
Actas Dermo-Sifiliográficas, 2010Co-Authors: Elisabeth Gomezmoyano, A Crespoerchiga, Vera A Casano, Sanz A TrellesAbstract:Un varon de 56 anos se encontraba en la segunda semana de tratamiento con imiquimod crema 5% por un carcinoma basocelular superficial localizado en la espalda cuando desarrollo un cuadro pseudogripal acompanado de una erupcion eritematodescamativa que se inicio en la cabeza y se extendio rapidamente con progresion craneocaudal. A la exploracion se objetivaba una eritrodermia con pequenos islotes de piel sana y un incipiente engrosamiento anaranjado en las palmas y las plantas. En la cara se apreciaba un eritema anaranjado junto a un leve ectropion. En el torax se observaban pequenas papulas queratosicas foliculares (fig. 1). Las mucosas estaban respetadas. Se tomaron 2 biopsias cutaneas, una del abdomen y otra de una papula queratosica del torax, y ambas mostraron hallazgos identicos. Se apreciaba una paraqueratosis alternante junto a areas de disqueratosis focal con acantolisis, discreta espongiosis y un infiltrado linfocitario en la dermis superficial en banda (fig. 2). Los resultados analiticos fueron normales y la serologia para HIV resulto negativa. El tratamiento con imiquimod fue suspendido y se inicio acitretino a dosis de 35mg/d con completa resolucion de las lesiones tras 2 meses de tratamiento. El paciente rechazo estudio alergologico para descartar un posible papel del imiquimod en el desarrollo del
Irit Allon - One of the best experts on this subject based on the ideXlab platform.
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warty dyskeratoma focal Acantholytic Dyskeratosis an update on a rare oral lesion
Journal of Oral Pathology & Medicine, 2012Co-Authors: Irit Allon, Amos BuchnerAbstract:J Oral Pathol Med (2012) 41: 261–267 Background: Warty dyskeratoma (WD) is an uncommon lesion of the skin that is considered to be associated with the pilosebaceous apparatus. Histologically similar lesions have been described in the oral region mainly by case reports and under the terms ‘WD’ or ‘focal Acantholytic Dyskeratosis (FAD)’. Owing to the paucity of reports, many aspects of the oral lesions remain unclear. The purpose of this study is to report a new case in an extremely rare location, the buccal mucosa, and to present a comprehensive updated review and analysis of the literature. Methods: We reviewed all cases of oral lesions that were diagnosed as WD and FAD and analyzed them according to their clinical and pathologic features. Results: The search yielded only 41 cases. The lesions usually appeared as asymptomatic, solitary, white nodules, papules, or patches on bone-bound mucosa. They occasionally had a rough surface and depressed center. The lesions were most common in the fifth to seventh decades. Use of tobacco appeared to be the most prevalent predisposing factor. The histopathological differential diagnosis of the lesion included Acantholytic squamous cell carcinoma, keratoacanthoma, and Darier’s disease. Conclusion: Warty dyskeratoma/FAD are uncommon oral lesions which are not encountered in the daily practice of oral pathologists. The absence of an association of oral lesions with the pilosebaceous apparatus suggests that they are probably distinctly different from cutaneous ones. As such, we suggest the histologic term isolated FAD for oral lesions, rather than WD.
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Warty dyskeratoma/focal Acantholytic Dyskeratosis--an update on a rare oral lesion.
Journal of Oral Pathology & Medicine, 2011Co-Authors: Irit Allon, Amos BuchnerAbstract:J Oral Pathol Med (2012) 41: 261–267 Background: Warty dyskeratoma (WD) is an uncommon lesion of the skin that is considered to be associated with the pilosebaceous apparatus. Histologically similar lesions have been described in the oral region mainly by case reports and under the terms ‘WD’ or ‘focal Acantholytic Dyskeratosis (FAD)’. Owing to the paucity of reports, many aspects of the oral lesions remain unclear. The purpose of this study is to report a new case in an extremely rare location, the buccal mucosa, and to present a comprehensive updated review and analysis of the literature. Methods: We reviewed all cases of oral lesions that were diagnosed as WD and FAD and analyzed them according to their clinical and pathologic features. Results: The search yielded only 41 cases. The lesions usually appeared as asymptomatic, solitary, white nodules, papules, or patches on bone-bound mucosa. They occasionally had a rough surface and depressed center. The lesions were most common in the fifth to seventh decades. Use of tobacco appeared to be the most prevalent predisposing factor. The histopathological differential diagnosis of the lesion included Acantholytic squamous cell carcinoma, keratoacanthoma, and Darier’s disease. Conclusion: Warty dyskeratoma/FAD are uncommon oral lesions which are not encountered in the daily practice of oral pathologists. The absence of an association of oral lesions with the pilosebaceous apparatus suggests that they are probably distinctly different from cutaneous ones. As such, we suggest the histologic term isolated FAD for oral lesions, rather than WD.
M. Thill - One of the best experts on this subject based on the ideXlab platform.
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Successful laser therapy of a papular Acantholytic Dyskeratosis of the vulva: case report and review of literature
Archives of Gynecology and Obstetrics, 2010Co-Authors: C. J. Dittmer, C Rose, A. Hornemann, K. Diedrich, M. ThillAbstract:Background The papular Acantholytic Dyskeratosis summarizes a collection of papular skin lesions which occur in intertriginous areas and in the genital area. They show a very characteristic histology without the connection to a syndrome such as the Hailey–Hailey disease or the Darier disease. Methods We present the case of an affected 45-year-old woman and evaluate the laser therapy as therapeutic option. Results A long lasting reduction of the symptoms was achieved by paying special attention to involving the deep tissue layers while performing the laser therapy. Despite causing a long and painful healing process, this was the only way to achieve a lasting reduction of the symptoms. Conclusions Laser therapy in afflicted areas can improve the symptoms of the papular Acantholytic Dyskeratosis. The deep tissue laser therapy showed more success than the superficial laser therapy.
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Successful laser therapy of a papular Acantholytic Dyskeratosis of the vulva: case report and review of literature
Archives of Gynecology and Obstetrics, 2009Co-Authors: C. J. Dittmer, C Rose, A. Hornemann, K. Diedrich, M. ThillAbstract:Background The papular Acantholytic Dyskeratosis summarizes a collection of papular skin lesions which occur in intertriginous areas and in the genital area. They show a very characteristic histology without the connection to a syndrome such as the Hailey–Hailey disease or the Darier disease.
Elisabeth Gomezmoyano - One of the best experts on this subject based on the ideXlab platform.
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pityriasis rubra pilaris with focal Acantholytic Dyskeratosis during treatment with imiquimod 5 cream
Actas Dermo-Sifiliográficas, 2010Co-Authors: Elisabeth Gomezmoyano, A Crespoerchiga, Vera A Casano, Sanz A TrellesAbstract:Un varon de 56 anos se encontraba en la segunda semana de tratamiento con imiquimod crema 5% por un carcinoma basocelular superficial localizado en la espalda cuando desarrollo un cuadro pseudogripal acompanado de una erupcion eritematodescamativa que se inicio en la cabeza y se extendio rapidamente con progresion craneocaudal. A la exploracion se objetivaba una eritrodermia con pequenos islotes de piel sana y un incipiente engrosamiento anaranjado en las palmas y las plantas. En la cara se apreciaba un eritema anaranjado junto a un leve ectropion. En el torax se observaban pequenas papulas queratosicas foliculares (fig. 1). Las mucosas estaban respetadas. Se tomaron 2 biopsias cutaneas, una del abdomen y otra de una papula queratosica del torax, y ambas mostraron hallazgos identicos. Se apreciaba una paraqueratosis alternante junto a areas de disqueratosis focal con acantolisis, discreta espongiosis y un infiltrado linfocitario en la dermis superficial en banda (fig. 2). Los resultados analiticos fueron normales y la serologia para HIV resulto negativa. El tratamiento con imiquimod fue suspendido y se inicio acitretino a dosis de 35mg/d con completa resolucion de las lesiones tras 2 meses de tratamiento. El paciente rechazo estudio alergologico para descartar un posible papel del imiquimod en el desarrollo del
