The Experts below are selected from a list of 360 Experts worldwide ranked by ideXlab platform
Shinichi Watanabe - One of the best experts on this subject based on the ideXlab platform.
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Pedunculated clear cell Acanthoma. Report of a case with dermoscopic observation
European Journal of Dermatology, 2010Co-Authors: Takamitsu Tanaka, Takamitsu Ohnishi, Takako Arai, Takeko Ishikawa, Shinichi WatanabeAbstract:Auteur(s) : Takamitsu Tanaka, Takako Arai, Takeko Ishikawa, Takamitsu Ohnishi, Shinichi Watanabe Department of Dermatology, Teikyo University School of Medicine, 11-1, Kaga, 2-chome, Itabashi-ku, Tokyo 173-8605, Japan Clear cell Acanthoma is a distinct clinical and histological entity that was first described in 1962 by Degos et al. The clinical appearance is usually characterized by a nodule or plaque with thin scaly-crusts on the legs, although considerable variety exists. Silhouette [...]
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Immunohistochemical characterization of keratin expression in clear cell Acanthoma.
British Journal of Dermatology, 1995Co-Authors: Takamitsu Ohnishi, Shinichi WatanabeAbstract:Summary The nature of clear cell Acanthoma has not been clarified, although many hypotheses have been proposed, including a benign neoplasm derived from epidermis or the acrosyringium, or a non-specific dermatosis. In this study, seven cases of clear cell Acanthoma were analysed by immunohistochemical techniques, using various monoclonal antikeratin antibodies, and antibodies against filaggrin, involucrin and epithelial membrane antigen. Different immunoreactivities were noted between clear cell Acanthoma and a normal eccrine gland, including the acrosyringium. Immuno-reactivities of clear cell Acanthoma were almost identical to those of normal epidermis, although some antibodies gave a different staining pattern between clear cell Acanthoma and normal epidermis. The expression of cytokeratins in psoriatic epidermis has been reported to change as a result of abnormal differentiation or maturation. Clear cell Acanthoma showed a similar staining pattern to inflammatory dermatoses such as psoriasis vulgaris, lichen planus and discoid lupus erythematosus. We speculate that clear cell Acanthoma is a localized form of inflammatory dermatosis rather than a neoplasm.
Piergiacomo Calzavara-pinton - One of the best experts on this subject based on the ideXlab platform.
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Multiple eruptive clear cell Acanthoma.
Journal of Dermatological Case Reports, 2010Co-Authors: Paola Daniela Monari, Giovanni Gualdi, Farisoglio C, Giorgio Botali, Marco Ungari, Piergiacomo Calzavara-pintonAbstract:Background: Clear cell Acanthoma is a rare solitary benign epidermal tumor of unknown etiology. The disease arises in the middle-age, with no sex predominance. It appears as a single reddish papule or papule-nodule and a peripheral scaling collarette is characteristic. Although solitary lesions are the rule, less than 30 cases of multiple Clear cell Acanthoma have been described in the literature to date. Main observations: We report an unusual case of a healthy 74-year-old male with multiple clear cell Acanthoma on the lower extremities treated successfully with cryotherapy. Conclusion: Despite significant progress in treatment of clear cell Acanthoma, cryotherapy, based on liquid nitrogen, remains an important alternative in treating multiple clear cell Acanthomas.
Ag Knight - One of the best experts on this subject based on the ideXlab platform.
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Polypoid clear cell Acanthoma: case report
Journal of the European Academy of Dermatology and Venereology, 2000Co-Authors: Hs Inalöz, G. Patel, Ag KnightAbstract:Clear cell Acanthoma of Degos is a rare benign tumour of epidermal origin with distinct histological features. Clinically, clear cell Acanthoma is characterized by a ‘stuck on’ appearance of a nodule or dome-shaped plaque that usually occurs on the legs of middle-aged or elderly persons. We observed an unusual case of polypoid clear cell Acanthoma on the right thigh of a 58-year-old male.
Takamitsu Ohnishi - One of the best experts on this subject based on the ideXlab platform.
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Pedunculated clear cell Acanthoma. Report of a case with dermoscopic observation
European Journal of Dermatology, 2010Co-Authors: Takamitsu Tanaka, Takamitsu Ohnishi, Takako Arai, Takeko Ishikawa, Shinichi WatanabeAbstract:Auteur(s) : Takamitsu Tanaka, Takako Arai, Takeko Ishikawa, Takamitsu Ohnishi, Shinichi Watanabe Department of Dermatology, Teikyo University School of Medicine, 11-1, Kaga, 2-chome, Itabashi-ku, Tokyo 173-8605, Japan Clear cell Acanthoma is a distinct clinical and histological entity that was first described in 1962 by Degos et al. The clinical appearance is usually characterized by a nodule or plaque with thin scaly-crusts on the legs, although considerable variety exists. Silhouette [...]
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Immunohistochemical characterization of keratin expression in clear cell Acanthoma.
British Journal of Dermatology, 1995Co-Authors: Takamitsu Ohnishi, Shinichi WatanabeAbstract:Summary The nature of clear cell Acanthoma has not been clarified, although many hypotheses have been proposed, including a benign neoplasm derived from epidermis or the acrosyringium, or a non-specific dermatosis. In this study, seven cases of clear cell Acanthoma were analysed by immunohistochemical techniques, using various monoclonal antikeratin antibodies, and antibodies against filaggrin, involucrin and epithelial membrane antigen. Different immunoreactivities were noted between clear cell Acanthoma and a normal eccrine gland, including the acrosyringium. Immuno-reactivities of clear cell Acanthoma were almost identical to those of normal epidermis, although some antibodies gave a different staining pattern between clear cell Acanthoma and normal epidermis. The expression of cytokeratins in psoriatic epidermis has been reported to change as a result of abnormal differentiation or maturation. Clear cell Acanthoma showed a similar staining pattern to inflammatory dermatoses such as psoriasis vulgaris, lichen planus and discoid lupus erythematosus. We speculate that clear cell Acanthoma is a localized form of inflammatory dermatosis rather than a neoplasm.
Paola Daniela Monari - One of the best experts on this subject based on the ideXlab platform.
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Multiple eruptive clear cell Acanthoma.
Journal of Dermatological Case Reports, 2010Co-Authors: Paola Daniela Monari, Giovanni Gualdi, Farisoglio C, Giorgio Botali, Marco Ungari, Piergiacomo Calzavara-pintonAbstract:Background: Clear cell Acanthoma is a rare solitary benign epidermal tumor of unknown etiology. The disease arises in the middle-age, with no sex predominance. It appears as a single reddish papule or papule-nodule and a peripheral scaling collarette is characteristic. Although solitary lesions are the rule, less than 30 cases of multiple Clear cell Acanthoma have been described in the literature to date. Main observations: We report an unusual case of a healthy 74-year-old male with multiple clear cell Acanthoma on the lower extremities treated successfully with cryotherapy. Conclusion: Despite significant progress in treatment of clear cell Acanthoma, cryotherapy, based on liquid nitrogen, remains an important alternative in treating multiple clear cell Acanthomas.