The Experts below are selected from a list of 2523 Experts worldwide ranked by ideXlab platform
Suhua Shi - One of the best experts on this subject based on the ideXlab platform.
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Transcriptome analysis of the Holly mangrove Acanthus ilicifolius and its terrestrial relative, Acanthus leucostachyus, provides insights into adaptation to intertidal zones.
BMC genomics, 2015Co-Authors: Yuchen Yang, Shuhuan Yang, Yunfei Deng, Zhang Zhang, Wuxia Guo, Cairong Zhong, Renchao Zhou, Suhua ShiAbstract:Background Acanthus is a unique genus consisting of both true mangrove and terrestrial species; thus, it represents an ideal system for studying the origin and adaptive evolution of mangrove plants to intertidal environments. However, little is known regarding the two respects of mangrove species in Acanthus. In this study, we sequenced the transcriptomes of the pooled roots and leaves tissues for a mangrove species, Acanthus ilicifolius, and its terrestrial congener, A. leucostachyus, to illustrate the origin of the mangrove species in this genus and their adaptive evolution to harsh habitats.
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Additional file 1: of Transcriptome analysis of the Holly mangrove Acanthus ilicifolius and its terrestrial relative, Acanthus leucostachyus, provides insights into adaptation to intertidal zones
2015Co-Authors: Yuchen Yang, Shuhuan Yang, Yunfei Deng, Zhang Zhang, Wuxia Guo, Cairong Zhong, Renchao Zhou, Suhua ShiAbstract:Length distribution of the contigs after removing redundancy in Acanthus ilicifolius (red) and A. leucostachyus (blue). (PDF 261Â kb)
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Additional file 3: of Transcriptome analysis of the Holly mangrove Acanthus ilicifolius and its terrestrial relative, Acanthus leucostachyus, provides insights into adaptation to intertidal zones
2015Co-Authors: Yuchen Yang, Shuhuan Yang, Yunfei Deng, Zhang Zhang, Wuxia Guo, Cairong Zhong, Renchao Zhou, Suhua ShiAbstract:Pairwise Kimura two-parameter distances of nrITS for the six Acanthus species. The abbreviations were listed in Additional file 9. (XLSX 9Â kb)
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Additional file 2: of Transcriptome analysis of the Holly mangrove Acanthus ilicifolius and its terrestrial relative, Acanthus leucostachyus, provides insights into adaptation to intertidal zones
2015Co-Authors: Yuchen Yang, Shuhuan Yang, Yunfei Deng, Zhang Zhang, Wuxia Guo, Cairong Zhong, Renchao Zhou, Suhua ShiAbstract:Pairwise synonymous substitution rate (Ks) of the three nuclear loci for the six Acanthus species. The abbreviations were listed in Additional file 9. (XLSX 9Â kb)
Yuchen Yang - One of the best experts on this subject based on the ideXlab platform.
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Transcriptome analysis of the Holly mangrove Acanthus ilicifolius and its terrestrial relative, Acanthus leucostachyus, provides insights into adaptation to intertidal zones.
BMC genomics, 2015Co-Authors: Yuchen Yang, Shuhuan Yang, Yunfei Deng, Zhang Zhang, Wuxia Guo, Cairong Zhong, Renchao Zhou, Suhua ShiAbstract:Background Acanthus is a unique genus consisting of both true mangrove and terrestrial species; thus, it represents an ideal system for studying the origin and adaptive evolution of mangrove plants to intertidal environments. However, little is known regarding the two respects of mangrove species in Acanthus. In this study, we sequenced the transcriptomes of the pooled roots and leaves tissues for a mangrove species, Acanthus ilicifolius, and its terrestrial congener, A. leucostachyus, to illustrate the origin of the mangrove species in this genus and their adaptive evolution to harsh habitats.
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Additional file 1: of Transcriptome analysis of the Holly mangrove Acanthus ilicifolius and its terrestrial relative, Acanthus leucostachyus, provides insights into adaptation to intertidal zones
2015Co-Authors: Yuchen Yang, Shuhuan Yang, Yunfei Deng, Zhang Zhang, Wuxia Guo, Cairong Zhong, Renchao Zhou, Suhua ShiAbstract:Length distribution of the contigs after removing redundancy in Acanthus ilicifolius (red) and A. leucostachyus (blue). (PDF 261Â kb)
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Additional file 3: of Transcriptome analysis of the Holly mangrove Acanthus ilicifolius and its terrestrial relative, Acanthus leucostachyus, provides insights into adaptation to intertidal zones
2015Co-Authors: Yuchen Yang, Shuhuan Yang, Yunfei Deng, Zhang Zhang, Wuxia Guo, Cairong Zhong, Renchao Zhou, Suhua ShiAbstract:Pairwise Kimura two-parameter distances of nrITS for the six Acanthus species. The abbreviations were listed in Additional file 9. (XLSX 9Â kb)
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Additional file 2: of Transcriptome analysis of the Holly mangrove Acanthus ilicifolius and its terrestrial relative, Acanthus leucostachyus, provides insights into adaptation to intertidal zones
2015Co-Authors: Yuchen Yang, Shuhuan Yang, Yunfei Deng, Zhang Zhang, Wuxia Guo, Cairong Zhong, Renchao Zhou, Suhua ShiAbstract:Pairwise synonymous substitution rate (Ks) of the three nuclear loci for the six Acanthus species. The abbreviations were listed in Additional file 9. (XLSX 9Â kb)
Sanmoy Karmakar - One of the best experts on this subject based on the ideXlab platform.
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The Gastroprotective Role of Acanthus ilicifolius – A Study to Unravel the Underlying Mechanism of Anti-Ulcer Activity
Scientia pharmaceutica, 2012Co-Authors: K. T. Mani Senthil Kumar, Zothan Puia, Samir K. Samanta, Rajiv Barik, Arnab Dutta, Bapi Gorain, Dilip Kumar Roy, Dipan Adhikari, Sanmoy Karmakar, Tuhinadri SenAbstract:Acanthus ilicifolius (Acanthaceae), a mangrove medicinal plant, is widely used by the local inhabitants of the Sundarbans (India) to treat a variety of diseases. As a part of our continued search for novel bioactive products from mangrove medicinal plants, we were able to document the anti-inflammatory effects of this plant. In the present study, we have performed a detailed evaluation of the gastroprotective activity of the methanolic extract of Acanthus ilicifolius using different models of gastric ulceration. Unlike the conventional non-steroidal anti-inflammatory drugs, a methanolic extract of Acanthus ilicifolius leaves (MEAL) possessing significant anti-inflammatory properties, as revealed from our previous studies displayed in rats in dosages of 200 mg and 400 mg / kg BW after intraperitoneal administration, showed significant protective activity (anti-ulcer activity) against the gastric lesions induced by aspirin, indomethacin, stress, ethanol, and pylorus ligation. In pylorus-ligated rats, administration of Methanolic extract of Acanthus ilicifolius leaves (MEAL) significantly decreased gastric volume, acidity, and peptic activity. Moreover, pre-treatment with MEAL significantly restored the levels of reduced glutathione (GSH) and the antioxidant enzyme superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPX), along with significant inhibition of both lipid peroxidation and myeloperoxidase (MPO) activity in pylorus-ligated animals. Ulceration induced with ethanol was significantly inhibited with MEAL, and the extract also resulted in the reduction of both lipid peroxidation and myelo-peroxidase activity. Furthermore, in this experimental model, administration of MEAL improved the activities of SOD, CAT, GSH, and GPX. A similar pattern of action was also noticed in cold-restraint stress-induced (CRS) ulceration, where MEAL pre-treatment inhibited CRS-induced ulceration, improved the status of antioxidant enzymes, and also reduced the level of lipid peroxides. These results suggest that extracts of the leaves of Acanthus ilicifolius may exhibit anti-ulcer activities additional to the anti-inflammatory properties.
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the gastroprotective role of Acanthus ilicifolius a study to unravel the underlying mechanism of anti ulcer activity
Scientia Pharmaceutica, 2012Co-Authors: K Mani Senthil T Kumar, Zothan Puia, Samir K. Samanta, Rajiv Barik, Arnab Dutta, Bapi Gorain, Dilip Kumar Roy, Dipan Adhikari, Sanmoy Karmakar, Tuhinadri SenAbstract:Acanthus ilicifolius (Acanthaceae), a mangrove medicinal plant, is widely used by the local inhabitants of the Sundarbans (India) to treat a variety of diseases. As a part of our continued search for novel bioactive products from mangrove medicinal plants, we were able to document the anti-inflammatory effects of this plant. In the present study, we have performed a detailed evaluation of the gastroprotective activity of the methanolic extract of Acanthus ilicifolius using different models of gastric ulceration. Unlike the conventional non-steroidal anti-inflammatory drugs, a methanolic extract of Acanthus ilicifolius leaves (MEAL) possessing significant anti-inflammatory properties, as revealed from our previous studies displayed in rats in dosages of 200 mg and 400 mg / kg BW after intraperitoneal administration, showed significant protective activity (anti-ulcer activity) against the gastric lesions induced by aspirin, indomethacin, stress, ethanol, and pylorus ligation. In pylorus-ligated rats, administration of Methanolic extract of Acanthus ilicifolius leaves (MEAL) significantly decreased gastric volume, acidity, and peptic activity. Moreover, pre-treatment with MEAL significantly restored the levels of reduced glutathione (GSH) and the antioxidant enzyme superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPX), along with significant inhibition of both lipid peroxidation and myeloperoxidase (MPO) activity in pylorus-ligated animals. Ulceration induced with ethanol was significantly inhibited with MEAL, and the extract also resulted in the reduction of both lipid peroxidation and myelo-peroxidase activity. Furthermore, in this experimental model, administration of MEAL improved the activities of SOD, CAT, GSH, and GPX. A similar pattern of action was also noticed in cold-restraint stress-induced (CRS) ulceration, where MEAL pre-treatment inhibited CRS-induced ulceration, improved the status of antioxidant enzymes, and also reduced the level of lipid peroxides. These results suggest that extracts of the leaves of Acanthus ilicifolius may exhibit anti-ulcer activities additional to the anti-inflammatory properties.
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Anti-inflammatory activity of Acanthus ilicifolius.
Journal of ethnopharmacology, 2008Co-Authors: K. T. Mani Senthil Kumar, Samir K. Samanta, Bapi Gorain, Dilip Kumar Roy, Dipan Adhikari, Zothanpuia, Mintu Pal, Prova Biswas, Amrita Roy, Sanmoy KarmakarAbstract:Acanthus ilicifolius Linn, is a perennial herb (Acanthaceae) widely found in the Sundarban mangroves and is popularly used for its wound healing effects. In the present study an attempt was made to evaluate the anti-inflammatory activity of the Acanthus ilicifolius leaves. The methanolic fraction of Acanthus ilicifolius leaf extract produced significant inhibition of rat paw oedema, when administered both prior to and after carrageenan administration, in a manner similar to BW755C a synthetic cyclooxygenase (COX) and lipoxygenase (LOX) inhibitor. The extract decreased protein exudation and leukocyte migration in the peritoneal fluid, thereby indicating its effectiveness towards inhibiting peritoneal inflammation. It also produced significant inhibition of COX (1 and 2) and 5-LOX activity. Preincubation of the extract inhibited the production of proinflammatory cytokines (TNFalpha and IL-6) in lipopolysaccharide (LPS)-stimulated peripheral blood mononuclear cells (PBMCs). The methanolic fraction of the extract was also found to possess significant free radical (DPPH, ABTS, superoxide and hydroxyl radical) scavenging activity. The extract on intraperitoneal administration augmented the endogenous antioxidant status, as evident from the significant increase of ferric reducing ability of plasma (FRAP) and total peroxyl radical trapping activity of plasma (TRAP).
Shuhuan Yang - One of the best experts on this subject based on the ideXlab platform.
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Transcriptome analysis of the Holly mangrove Acanthus ilicifolius and its terrestrial relative, Acanthus leucostachyus, provides insights into adaptation to intertidal zones.
BMC genomics, 2015Co-Authors: Yuchen Yang, Shuhuan Yang, Yunfei Deng, Zhang Zhang, Wuxia Guo, Cairong Zhong, Renchao Zhou, Suhua ShiAbstract:Background Acanthus is a unique genus consisting of both true mangrove and terrestrial species; thus, it represents an ideal system for studying the origin and adaptive evolution of mangrove plants to intertidal environments. However, little is known regarding the two respects of mangrove species in Acanthus. In this study, we sequenced the transcriptomes of the pooled roots and leaves tissues for a mangrove species, Acanthus ilicifolius, and its terrestrial congener, A. leucostachyus, to illustrate the origin of the mangrove species in this genus and their adaptive evolution to harsh habitats.
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Additional file 1: of Transcriptome analysis of the Holly mangrove Acanthus ilicifolius and its terrestrial relative, Acanthus leucostachyus, provides insights into adaptation to intertidal zones
2015Co-Authors: Yuchen Yang, Shuhuan Yang, Yunfei Deng, Zhang Zhang, Wuxia Guo, Cairong Zhong, Renchao Zhou, Suhua ShiAbstract:Length distribution of the contigs after removing redundancy in Acanthus ilicifolius (red) and A. leucostachyus (blue). (PDF 261Â kb)
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Additional file 3: of Transcriptome analysis of the Holly mangrove Acanthus ilicifolius and its terrestrial relative, Acanthus leucostachyus, provides insights into adaptation to intertidal zones
2015Co-Authors: Yuchen Yang, Shuhuan Yang, Yunfei Deng, Zhang Zhang, Wuxia Guo, Cairong Zhong, Renchao Zhou, Suhua ShiAbstract:Pairwise Kimura two-parameter distances of nrITS for the six Acanthus species. The abbreviations were listed in Additional file 9. (XLSX 9Â kb)
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Additional file 2: of Transcriptome analysis of the Holly mangrove Acanthus ilicifolius and its terrestrial relative, Acanthus leucostachyus, provides insights into adaptation to intertidal zones
2015Co-Authors: Yuchen Yang, Shuhuan Yang, Yunfei Deng, Zhang Zhang, Wuxia Guo, Cairong Zhong, Renchao Zhou, Suhua ShiAbstract:Pairwise synonymous substitution rate (Ks) of the three nuclear loci for the six Acanthus species. The abbreviations were listed in Additional file 9. (XLSX 9Â kb)
Yunfei Deng - One of the best experts on this subject based on the ideXlab platform.
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Transcriptome analysis of the Holly mangrove Acanthus ilicifolius and its terrestrial relative, Acanthus leucostachyus, provides insights into adaptation to intertidal zones.
BMC genomics, 2015Co-Authors: Yuchen Yang, Shuhuan Yang, Yunfei Deng, Zhang Zhang, Wuxia Guo, Cairong Zhong, Renchao Zhou, Suhua ShiAbstract:Background Acanthus is a unique genus consisting of both true mangrove and terrestrial species; thus, it represents an ideal system for studying the origin and adaptive evolution of mangrove plants to intertidal environments. However, little is known regarding the two respects of mangrove species in Acanthus. In this study, we sequenced the transcriptomes of the pooled roots and leaves tissues for a mangrove species, Acanthus ilicifolius, and its terrestrial congener, A. leucostachyus, to illustrate the origin of the mangrove species in this genus and their adaptive evolution to harsh habitats.
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Additional file 1: of Transcriptome analysis of the Holly mangrove Acanthus ilicifolius and its terrestrial relative, Acanthus leucostachyus, provides insights into adaptation to intertidal zones
2015Co-Authors: Yuchen Yang, Shuhuan Yang, Yunfei Deng, Zhang Zhang, Wuxia Guo, Cairong Zhong, Renchao Zhou, Suhua ShiAbstract:Length distribution of the contigs after removing redundancy in Acanthus ilicifolius (red) and A. leucostachyus (blue). (PDF 261Â kb)
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Additional file 3: of Transcriptome analysis of the Holly mangrove Acanthus ilicifolius and its terrestrial relative, Acanthus leucostachyus, provides insights into adaptation to intertidal zones
2015Co-Authors: Yuchen Yang, Shuhuan Yang, Yunfei Deng, Zhang Zhang, Wuxia Guo, Cairong Zhong, Renchao Zhou, Suhua ShiAbstract:Pairwise Kimura two-parameter distances of nrITS for the six Acanthus species. The abbreviations were listed in Additional file 9. (XLSX 9Â kb)
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Additional file 2: of Transcriptome analysis of the Holly mangrove Acanthus ilicifolius and its terrestrial relative, Acanthus leucostachyus, provides insights into adaptation to intertidal zones
2015Co-Authors: Yuchen Yang, Shuhuan Yang, Yunfei Deng, Zhang Zhang, Wuxia Guo, Cairong Zhong, Renchao Zhou, Suhua ShiAbstract:Pairwise synonymous substitution rate (Ks) of the three nuclear loci for the six Acanthus species. The abbreviations were listed in Additional file 9. (XLSX 9Â kb)
