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Acid-Base Imbalance

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Richard Treger – One of the best experts on this subject based on the ideXlab platform.

  • assessing acid base status in circulatory failure relationship between arterial and peripheral venous blood gas measurements in hypovolemic shock
    Journal of Intensive Care Medicine, 2020
    Co-Authors: Scott E Rudkin, Craig L Anderson, Tristan Grogan, David Elashoff, Richard Treger

    Abstract:

    Background and Objectives:In severe circulatory failure agreement between arterial and mixed venous or central venous values is poor; venous values are more reflective of tissue acid–base Imbalance

Li Jing – One of the best experts on this subject based on the ideXlab platform.

  • An analysis on the triple Acid-Base Imbalance in chronic cor pulmonale during acute attack
    Journal of Xinjiang Medical University, 2006
    Co-Authors: Li Jing

    Abstract:

    Objective: To analyze the blood-gas and electrolyte changes of triple Acid-Base Imbalance in chronic cor pulmonale during acute attack,and discuss the causes and prevention.Methods: Blood-gas and assays were analyzed in 250 patients with chronic cor pulmonale during acute attack;the results of 28 patients with triple Acid-Base Imbalances were compared with 32 patients with normal blood-gas.Results: Twenty of 28 patients with triple Acid-Base Imbalances were repiratory acidosis type,with lower pH,Cl~-and higher PaCO_2 and HCO_3~-;8 patients were respiratory alkalosis type,with lower PaCO_2,HCO_3~-and Cl~-compare to normal group,respectively.Conclusions: The morbidity of the triple Acid-Base Imbalance in chronic cor pulmonale during acute attack is high,mostly with respiratory acidosis type;to discover and treat the triple Acid-Base Imbalance in chronic cor pulmonale during acute attack is one of the critical element leading to a successful treatment.

Nilofar Massoudi – One of the best experts on this subject based on the ideXlab platform.

  • The Effect of Intraoperative Alkali Treatment on Recovery from Atracurium-Induced Neuromuscular Blockade in Renal Transplantation: A Randomized Trial
    Anesthesiology and Pain Medicine, 2017
    Co-Authors: Navid Noraee, Mohammad Fathi, Majid Golestani Eraghi, Ali Dabbagh, Nilofar Massoudi

    Abstract:

    Intraoperative care and anesthesia method in patients undergoing allograft renal transplantation surgery are very necessary. Acid-Base Imbalance can alter neuromuscular blockade and recovery time.The aim of the present study was to investigate the effect of Acid-Base balance on atracurium blockade in renal transplantation.In this randomized-controlled trial, 31 end-stage renal disease (ESRD) patients undergoing renal transplantation were randomly assigned into two equal groups. The case group received intravenous sodium bicarbonate based on base excess in the first ABG sample, while the control group received sterile water for injection during the interval between anesthesia and beginning of surgery. Arterial blood gas (ABG) sample was drawn first prior to surgery and again at declamping time. Train-of-four (TOF) was measured before anesthesia and repeatedly after declamping time until acceptable recovery (TOF 3 of 4). The time of achieving TOF 3 was recorded and compared between the groups.There was no significant difference in blood pH between the groups in the first evaluation (P = 0.649). The pH and base excess (BE) in the case group significantly increased after the intervention. There was a significant decrease in after-surgery measurement of pH in the control group (P = 0.011). The mean time to achieve TOF = 3 was 23.75 ± 5.32 and 41.80 ± 5.2 minutes after declamping in the case and control groups, respectively. Patients in the sodium bicarbonate group achieved TOF = 3 significantly faster than the control group.Based on our results, intraoperative alkali and Acid-Base Imbalance treatment can reduce neuromuscular blockade and recovery time, and it can be regarded as a potential casual factor to enhance transplantation outcome.