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Suzanna M Zick - One of the best experts on this subject based on the ideXlab platform.

  • self administered Acupressure for chronic low back pain a randomized controlled pilot trial
    2019
    Co-Authors: Susan L Murphy, Richard E Harris, Nahid Roonizi Keshavarzi, Suzanna M Zick
    Abstract:

    Objective Chronic low back pain (CLBP) is associated with fatigue, pain, poor sleep, and disability. Acupressure is a low-risk treatment option used to manage symptoms in other groups, but its efficacy, particularly on fatigue and sleep, is unknown in CLBP. This study examined preliminary effects of two types of self-administered Acupressure (relaxing and stimulating) on fatigue, pain, sleep, and reported disability. Methods A randomized pilot trial was conducted (N = 67) in which participants were randomized into six weeks of relaxing Acupressure, stimulating Acupressure, or usual care. Fatigue was measured by the Brief Fatigue Inventory, pain was measured by the Brief Pain Inventory, sleep was measured by the Pittsburgh Sleep Quality Index, and reported disability was measured by the Roland Morris Scale. Results Baseline characteristics were similar across groups. An intent-to-treat analysis using general linear models showed positive improvement in pain in Acupressure groups compared with usual care. Pain was reduced by 35-36% in the Acupressure groups. Improvement in fatigue was also found in stimulating Acupressure compared with usual care. Adverse events were minimal and related to application of too much pressure. Discussion Although this was a small study, Acupressure demonstrated promising preliminary support of efficacy for pain and fatigue reduction in this population.

  • impact of self Acupressure on co occurring symptoms in cancer survivors
    2018
    Co-Authors: Suzanna M Zick, Ananda Sen, Afton L Hassett, Andrew Schrepf, Gwen Wyatt, Susan L Murphy, John Todd Arnedt, Richard E Harris
    Abstract:

    Background Cancer survivors with fatigue often experience depressive symptoms, anxiety, and pain. Previously, we reported that self-Acupressure improved fatigue; however, its impact on other co-occurring symptoms and their involvement in treatment action has not been explored. Methods Changes in depressive symptoms, anxiety, and pain were examined prior to and following two formulas of self-Acupressure and usual care using linear mixed models in 288 women from a previously reported clinical trial. Participants were categorized by random assignment into one of three groups: 1) relaxing Acupressure, 2) stimulating Acupressure, or 3) usual care. Moderators investigated were body mass index, age, depressive symptoms, anxiety, sleep and pain, and mediators were change in these symptoms. Results Following treatment, depressive symptoms improved statistically significantly for the relaxing Acupressure group (41.5%) compared with stimulating Acupressure (25%) and usual care (7.7%). Both Acupressure groups were associated with greater improvements in anxiety than usual care, but only relaxing Acupressure was associated with greater reductions in pain severity, and only stimulating Acupressure was associated with greater reductions in pain interference. There were no statistically significant moderators of sleep quality, anxiety, or depressive symptoms. Fatigue statistically significantly moderated pain, and age statistically significantly modified fatigue. Changes in depressive symptoms and sleep quality statistically significantly mediated the relationship between relaxing Acupressure and usual care on fatigue; however, the effect was small. Conclusions Acupressure was associated with greater improvements than usual care in anxiety, pain, and symptoms of depression in breast cancer survivors with troublesome fatigue. These findings warrant further evaluation in suitably controlled randomized trials.

  • brain connectivity patterns dissociate action of specific Acupressure treatments in fatigued breast cancer survivors
    2017
    Co-Authors: Richard E Harris, Eric Ichesco, Chelsea M Cummiford, Johnson P Hampson, Thomas L Chenevert, Neil Basu, Suzanna M Zick
    Abstract:

    Persistent fatigue is a pernicious symptom in many cancer survivors. Existing treatments are limited or ineffective, and often lack any underlying biologic rationale. Acupressure is emerging as a promising new intervention for persistent cancer related fatigue; however, the underlying mechanisms of action are unknown. Our previous investigations suggested that fatigued breast cancer survivors have alterations in brain neurochemistry within the posterior insula and disturbed functional connectivity to the default mode network (DMN), as compared to non-fatigued breast cancer survivors. Here we investigated if insula and DMN connectivity were modulated by self-administered Acupressure by randomizing breast cancer survivors (n=19) to two distinct treatments: relaxing Acupressure or stimulating Acupressure. All participants underwent proton magnetic resonance spectroscopy of the posterior insula and functional connectivity magnetic resonance imaging at baseline and immediately following 6 weeks of Acupressure self-treatment. As compared to baseline measures, relaxing Acupressure decreased posterior insula to dorsolateral prefrontal cortex connectivity whereas stimulating Acupressure enhanced this connectivity (p<0.05 corrected). For relaxing but not stimulating Acupressure, reduced connectivity was associated with sleep improvement. In addition, connectivity of the DMN to the superior colliculus was increased with relaxing Acupressure and decreased with stimulating Acupressure, whereas DMN connectivity to the bilateral pulvinar was increased with stimulating and decreased with relaxing Acupressure (p<0.05 corrected). These data suggest that self-administered Acupressure at different acupoints has specificity in relation to their mechanisms of action in fatigued breast cancer survivors.

  • investigation of 2 types of self administered Acupressure for persistent cancer related fatigue in breast cancer survivors a randomized clinical trial
    2016
    Co-Authors: Suzanna M Zick, Ananda Sen, Gwen Wyatt, Susan L Murphy, Todd J Arnedt, Richard E Harris
    Abstract:

    Importance Fatigue is a common and debilitating late-term effect of breast cancer that is associated with poor sleep and decreased quality of life, yet therapies remain limited. Acupressure has reduced fatigue in previous small studies, but rigorous clinical trials are needed. Objectives To investigate if 6 weeks of 2 types of self-administered Acupressure improved fatigue, sleep, and quality of life vs usual care in breast cancer survivors and to determine if changes were sustained during a 4-week washout period. Design, Setting, and Participants Phase 3 randomized, single-blind, clinical trial conducted from March 1, 2011, through October 31, 2014. Women were recruited from the Michigan Tumor Registry. Interventions Randomization (1:1:1) to 6 weeks of daily self-administered relaxing Acupressure, stimulating Acupressure, or usual care. Main Outcomes and Measures The primary outcome was change in the Brief Fatigue Inventory score from baseline to weeks 6 and 10. Secondary analyses were sleep (Pittsburgh Sleep Quality Index) and quality of life (Long-Term Quality of Life Instrument). Results A total of 424 survivors of stages 0 to III breast cancer who had completed cancer treatments at least 12 months previously were screened, and 288 were randomized, with 270 receiving relaxing Acupressure (n = 94), stimulating Acupressure (n = 90), or usual care (n = 86). One woman withdrew owing to bruising at the acupoints. At week 6, the percentages of participants who achieved normal fatigue levels (Brief Fatigue Inventory score Conclusions and Relevance Both Acupressure arms significantly reduced persistent fatigue compared with usual care, but only relaxing Acupressure had significant effects on sleep quality and quality of life. Relaxing Acupressure offers a possible low-cost option for managing symptoms. Trial Registration clinicaltrials.gov Identifier:NCT01281904

  • Acupressure for persistent cancer related fatigue in breast cancer survivors acucrft a study protocol for a randomized controlled trial
    2012
    Co-Authors: Suzanna M Zick, Ananda Sen, Gwen Wyatt, Susan L Murphy, Todd J Arnedt, Richard E Harris
    Abstract:

    Despite high levels of clinically significant persistent cancer related fatigue in breast cancer survivors few treatments are currently available and most pose a significant burden on the part of the woman. Acupressure, a component of Traditional Chinese Medicine, has been shown to decrease fatigue levels by as much as 70% in cancer survivors while being inexpensive, non-toxic and an easy to use intervention. The primary aim of this study was to determine the efficacy of two types of self-administered Acupressure (relaxation Acupressure and stimulating Acupressure), compared to standard of care on fatigue severity. Secondary aims were to evaluate the efficacy of two types of Acupressure on sleep and kinetic parameters required for implementation of Acupressure in a clinical setting; The purpose of this paper is to share the methodology used including challenges and insights. This study is a three group, randomized clinical trial. 375 breast cancer survivors at least 12 months after completion of cancer treatments, with moderate to severe persistent fatigue, are being randomized to one of 3 groups: self-administered relaxation Acupressure; self-administered stimulating Acupressure; or standard of care. Participants are assessed at baseline, 3 weeks, and 6 weeks followed by a 4-week follow-up period. The primary aim is to examine the effect of 6-weeks of relaxation Acupressure compared to stimulatory Acupressure or standard of care on fatigue as assessed by: weekly self-report using the Brief Fatigue Inventory; objective daytime physical activity on actigraph; or fatigue patterns assessed 4-times daily using a visual analog scale. Secondary endpoints include depression, anxiety, self-efficacy, and sleep quality. This study has the potential to develop a low-cost, self-care intervention for the most troubling of late-term effects in breast cancer populations, fatigue. The methods used may lend constructive ideas to other investigators working with this population and/or intervention. ClinicalTrial.Gov Trials Register NCT01281904

Richard E Harris - One of the best experts on this subject based on the ideXlab platform.

  • self administered Acupressure for chronic low back pain a randomized controlled pilot trial
    2019
    Co-Authors: Susan L Murphy, Richard E Harris, Nahid Roonizi Keshavarzi, Suzanna M Zick
    Abstract:

    Objective Chronic low back pain (CLBP) is associated with fatigue, pain, poor sleep, and disability. Acupressure is a low-risk treatment option used to manage symptoms in other groups, but its efficacy, particularly on fatigue and sleep, is unknown in CLBP. This study examined preliminary effects of two types of self-administered Acupressure (relaxing and stimulating) on fatigue, pain, sleep, and reported disability. Methods A randomized pilot trial was conducted (N = 67) in which participants were randomized into six weeks of relaxing Acupressure, stimulating Acupressure, or usual care. Fatigue was measured by the Brief Fatigue Inventory, pain was measured by the Brief Pain Inventory, sleep was measured by the Pittsburgh Sleep Quality Index, and reported disability was measured by the Roland Morris Scale. Results Baseline characteristics were similar across groups. An intent-to-treat analysis using general linear models showed positive improvement in pain in Acupressure groups compared with usual care. Pain was reduced by 35-36% in the Acupressure groups. Improvement in fatigue was also found in stimulating Acupressure compared with usual care. Adverse events were minimal and related to application of too much pressure. Discussion Although this was a small study, Acupressure demonstrated promising preliminary support of efficacy for pain and fatigue reduction in this population.

  • impact of self Acupressure on co occurring symptoms in cancer survivors
    2018
    Co-Authors: Suzanna M Zick, Ananda Sen, Afton L Hassett, Andrew Schrepf, Gwen Wyatt, Susan L Murphy, John Todd Arnedt, Richard E Harris
    Abstract:

    Background Cancer survivors with fatigue often experience depressive symptoms, anxiety, and pain. Previously, we reported that self-Acupressure improved fatigue; however, its impact on other co-occurring symptoms and their involvement in treatment action has not been explored. Methods Changes in depressive symptoms, anxiety, and pain were examined prior to and following two formulas of self-Acupressure and usual care using linear mixed models in 288 women from a previously reported clinical trial. Participants were categorized by random assignment into one of three groups: 1) relaxing Acupressure, 2) stimulating Acupressure, or 3) usual care. Moderators investigated were body mass index, age, depressive symptoms, anxiety, sleep and pain, and mediators were change in these symptoms. Results Following treatment, depressive symptoms improved statistically significantly for the relaxing Acupressure group (41.5%) compared with stimulating Acupressure (25%) and usual care (7.7%). Both Acupressure groups were associated with greater improvements in anxiety than usual care, but only relaxing Acupressure was associated with greater reductions in pain severity, and only stimulating Acupressure was associated with greater reductions in pain interference. There were no statistically significant moderators of sleep quality, anxiety, or depressive symptoms. Fatigue statistically significantly moderated pain, and age statistically significantly modified fatigue. Changes in depressive symptoms and sleep quality statistically significantly mediated the relationship between relaxing Acupressure and usual care on fatigue; however, the effect was small. Conclusions Acupressure was associated with greater improvements than usual care in anxiety, pain, and symptoms of depression in breast cancer survivors with troublesome fatigue. These findings warrant further evaluation in suitably controlled randomized trials.

  • self Acupressure for older adults with symptomatic knee osteoarthritis a randomized controlled trial
    2018
    Co-Authors: Richard E Harris, Alexander Tsodikov, Laura M Struble, Susan L Murphy
    Abstract:

    Objective This double-blind randomized controlled trial aimed to test the efficacy of self-administered Acupressure for pain and physical function improvement for older adults with knee osteoarthritis (OA). Methods Participants were community-dwelling adults with symptomatic knee OA (n = 150, mean age 73 years), randomized to 1 of 3 groups: verum Acupressure, sham Acupressure, or usual care. Participants in the verum and sham groups, but not those in the usual care group, were taught to self-apply Acupressure once daily, 5 days/week for 8 weeks. Assessments were collected during center visits at baseline, and at 4 and 8 weeks. In addition, pain level was assessed weekly by phone using a numeric rating scale (NRS). Outcomes included the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) pain subscale (primary), and subjective and objective physical function measures and the NRS and physical function measures (secondary). Linear mixed regression analysis was conducted to test between-group differences in mean changes from baseline for the outcomes at 8 weeks. Results Compared with usual care, both verum and sham Acupressure participants experienced significant improvements in WOMAC pain (mean difference -1.27 units [95% confidence interval (95% CI) -1.95, -0.58] and -1.24 units [95% CI -1.92, -0.55], respectively), NRS pain (-0.74 units [95% CI -1.24, -0.24] and -0.51 units [95% CI -1.01, -0.01], respectively), and WOMAC function (-4.83 units [95% CI -6.99, -2.67] and -4.21 units [95% CI -6.37, -2.04], respectively) at 8 weeks. There were no significant differences between the verum and sham Acupressure groups on any of the outcomes. Conclusion Self-administered Acupressure is superior to usual care in pain and physical function improvement for older adults with knee OA. The reason for the benefits is unclear, and the placebo effect may play a role.

  • brain connectivity patterns dissociate action of specific Acupressure treatments in fatigued breast cancer survivors
    2017
    Co-Authors: Richard E Harris, Eric Ichesco, Chelsea M Cummiford, Johnson P Hampson, Thomas L Chenevert, Neil Basu, Suzanna M Zick
    Abstract:

    Persistent fatigue is a pernicious symptom in many cancer survivors. Existing treatments are limited or ineffective, and often lack any underlying biologic rationale. Acupressure is emerging as a promising new intervention for persistent cancer related fatigue; however, the underlying mechanisms of action are unknown. Our previous investigations suggested that fatigued breast cancer survivors have alterations in brain neurochemistry within the posterior insula and disturbed functional connectivity to the default mode network (DMN), as compared to non-fatigued breast cancer survivors. Here we investigated if insula and DMN connectivity were modulated by self-administered Acupressure by randomizing breast cancer survivors (n=19) to two distinct treatments: relaxing Acupressure or stimulating Acupressure. All participants underwent proton magnetic resonance spectroscopy of the posterior insula and functional connectivity magnetic resonance imaging at baseline and immediately following 6 weeks of Acupressure self-treatment. As compared to baseline measures, relaxing Acupressure decreased posterior insula to dorsolateral prefrontal cortex connectivity whereas stimulating Acupressure enhanced this connectivity (p<0.05 corrected). For relaxing but not stimulating Acupressure, reduced connectivity was associated with sleep improvement. In addition, connectivity of the DMN to the superior colliculus was increased with relaxing Acupressure and decreased with stimulating Acupressure, whereas DMN connectivity to the bilateral pulvinar was increased with stimulating and decreased with relaxing Acupressure (p<0.05 corrected). These data suggest that self-administered Acupressure at different acupoints has specificity in relation to their mechanisms of action in fatigued breast cancer survivors.

  • investigation of 2 types of self administered Acupressure for persistent cancer related fatigue in breast cancer survivors a randomized clinical trial
    2016
    Co-Authors: Suzanna M Zick, Ananda Sen, Gwen Wyatt, Susan L Murphy, Todd J Arnedt, Richard E Harris
    Abstract:

    Importance Fatigue is a common and debilitating late-term effect of breast cancer that is associated with poor sleep and decreased quality of life, yet therapies remain limited. Acupressure has reduced fatigue in previous small studies, but rigorous clinical trials are needed. Objectives To investigate if 6 weeks of 2 types of self-administered Acupressure improved fatigue, sleep, and quality of life vs usual care in breast cancer survivors and to determine if changes were sustained during a 4-week washout period. Design, Setting, and Participants Phase 3 randomized, single-blind, clinical trial conducted from March 1, 2011, through October 31, 2014. Women were recruited from the Michigan Tumor Registry. Interventions Randomization (1:1:1) to 6 weeks of daily self-administered relaxing Acupressure, stimulating Acupressure, or usual care. Main Outcomes and Measures The primary outcome was change in the Brief Fatigue Inventory score from baseline to weeks 6 and 10. Secondary analyses were sleep (Pittsburgh Sleep Quality Index) and quality of life (Long-Term Quality of Life Instrument). Results A total of 424 survivors of stages 0 to III breast cancer who had completed cancer treatments at least 12 months previously were screened, and 288 were randomized, with 270 receiving relaxing Acupressure (n = 94), stimulating Acupressure (n = 90), or usual care (n = 86). One woman withdrew owing to bruising at the acupoints. At week 6, the percentages of participants who achieved normal fatigue levels (Brief Fatigue Inventory score Conclusions and Relevance Both Acupressure arms significantly reduced persistent fatigue compared with usual care, but only relaxing Acupressure had significant effects on sleep quality and quality of life. Relaxing Acupressure offers a possible low-cost option for managing symptoms. Trial Registration clinicaltrials.gov Identifier:NCT01281904

Susan L Murphy - One of the best experts on this subject based on the ideXlab platform.

  • self administered Acupressure for chronic low back pain a randomized controlled pilot trial
    2019
    Co-Authors: Susan L Murphy, Richard E Harris, Nahid Roonizi Keshavarzi, Suzanna M Zick
    Abstract:

    Objective Chronic low back pain (CLBP) is associated with fatigue, pain, poor sleep, and disability. Acupressure is a low-risk treatment option used to manage symptoms in other groups, but its efficacy, particularly on fatigue and sleep, is unknown in CLBP. This study examined preliminary effects of two types of self-administered Acupressure (relaxing and stimulating) on fatigue, pain, sleep, and reported disability. Methods A randomized pilot trial was conducted (N = 67) in which participants were randomized into six weeks of relaxing Acupressure, stimulating Acupressure, or usual care. Fatigue was measured by the Brief Fatigue Inventory, pain was measured by the Brief Pain Inventory, sleep was measured by the Pittsburgh Sleep Quality Index, and reported disability was measured by the Roland Morris Scale. Results Baseline characteristics were similar across groups. An intent-to-treat analysis using general linear models showed positive improvement in pain in Acupressure groups compared with usual care. Pain was reduced by 35-36% in the Acupressure groups. Improvement in fatigue was also found in stimulating Acupressure compared with usual care. Adverse events were minimal and related to application of too much pressure. Discussion Although this was a small study, Acupressure demonstrated promising preliminary support of efficacy for pain and fatigue reduction in this population.

  • impact of self Acupressure on co occurring symptoms in cancer survivors
    2018
    Co-Authors: Suzanna M Zick, Ananda Sen, Afton L Hassett, Andrew Schrepf, Gwen Wyatt, Susan L Murphy, John Todd Arnedt, Richard E Harris
    Abstract:

    Background Cancer survivors with fatigue often experience depressive symptoms, anxiety, and pain. Previously, we reported that self-Acupressure improved fatigue; however, its impact on other co-occurring symptoms and their involvement in treatment action has not been explored. Methods Changes in depressive symptoms, anxiety, and pain were examined prior to and following two formulas of self-Acupressure and usual care using linear mixed models in 288 women from a previously reported clinical trial. Participants were categorized by random assignment into one of three groups: 1) relaxing Acupressure, 2) stimulating Acupressure, or 3) usual care. Moderators investigated were body mass index, age, depressive symptoms, anxiety, sleep and pain, and mediators were change in these symptoms. Results Following treatment, depressive symptoms improved statistically significantly for the relaxing Acupressure group (41.5%) compared with stimulating Acupressure (25%) and usual care (7.7%). Both Acupressure groups were associated with greater improvements in anxiety than usual care, but only relaxing Acupressure was associated with greater reductions in pain severity, and only stimulating Acupressure was associated with greater reductions in pain interference. There were no statistically significant moderators of sleep quality, anxiety, or depressive symptoms. Fatigue statistically significantly moderated pain, and age statistically significantly modified fatigue. Changes in depressive symptoms and sleep quality statistically significantly mediated the relationship between relaxing Acupressure and usual care on fatigue; however, the effect was small. Conclusions Acupressure was associated with greater improvements than usual care in anxiety, pain, and symptoms of depression in breast cancer survivors with troublesome fatigue. These findings warrant further evaluation in suitably controlled randomized trials.

  • self Acupressure for older adults with symptomatic knee osteoarthritis a randomized controlled trial
    2018
    Co-Authors: Richard E Harris, Alexander Tsodikov, Laura M Struble, Susan L Murphy
    Abstract:

    Objective This double-blind randomized controlled trial aimed to test the efficacy of self-administered Acupressure for pain and physical function improvement for older adults with knee osteoarthritis (OA). Methods Participants were community-dwelling adults with symptomatic knee OA (n = 150, mean age 73 years), randomized to 1 of 3 groups: verum Acupressure, sham Acupressure, or usual care. Participants in the verum and sham groups, but not those in the usual care group, were taught to self-apply Acupressure once daily, 5 days/week for 8 weeks. Assessments were collected during center visits at baseline, and at 4 and 8 weeks. In addition, pain level was assessed weekly by phone using a numeric rating scale (NRS). Outcomes included the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) pain subscale (primary), and subjective and objective physical function measures and the NRS and physical function measures (secondary). Linear mixed regression analysis was conducted to test between-group differences in mean changes from baseline for the outcomes at 8 weeks. Results Compared with usual care, both verum and sham Acupressure participants experienced significant improvements in WOMAC pain (mean difference -1.27 units [95% confidence interval (95% CI) -1.95, -0.58] and -1.24 units [95% CI -1.92, -0.55], respectively), NRS pain (-0.74 units [95% CI -1.24, -0.24] and -0.51 units [95% CI -1.01, -0.01], respectively), and WOMAC function (-4.83 units [95% CI -6.99, -2.67] and -4.21 units [95% CI -6.37, -2.04], respectively) at 8 weeks. There were no significant differences between the verum and sham Acupressure groups on any of the outcomes. Conclusion Self-administered Acupressure is superior to usual care in pain and physical function improvement for older adults with knee OA. The reason for the benefits is unclear, and the placebo effect may play a role.

  • investigation of 2 types of self administered Acupressure for persistent cancer related fatigue in breast cancer survivors a randomized clinical trial
    2016
    Co-Authors: Suzanna M Zick, Ananda Sen, Gwen Wyatt, Susan L Murphy, Todd J Arnedt, Richard E Harris
    Abstract:

    Importance Fatigue is a common and debilitating late-term effect of breast cancer that is associated with poor sleep and decreased quality of life, yet therapies remain limited. Acupressure has reduced fatigue in previous small studies, but rigorous clinical trials are needed. Objectives To investigate if 6 weeks of 2 types of self-administered Acupressure improved fatigue, sleep, and quality of life vs usual care in breast cancer survivors and to determine if changes were sustained during a 4-week washout period. Design, Setting, and Participants Phase 3 randomized, single-blind, clinical trial conducted from March 1, 2011, through October 31, 2014. Women were recruited from the Michigan Tumor Registry. Interventions Randomization (1:1:1) to 6 weeks of daily self-administered relaxing Acupressure, stimulating Acupressure, or usual care. Main Outcomes and Measures The primary outcome was change in the Brief Fatigue Inventory score from baseline to weeks 6 and 10. Secondary analyses were sleep (Pittsburgh Sleep Quality Index) and quality of life (Long-Term Quality of Life Instrument). Results A total of 424 survivors of stages 0 to III breast cancer who had completed cancer treatments at least 12 months previously were screened, and 288 were randomized, with 270 receiving relaxing Acupressure (n = 94), stimulating Acupressure (n = 90), or usual care (n = 86). One woman withdrew owing to bruising at the acupoints. At week 6, the percentages of participants who achieved normal fatigue levels (Brief Fatigue Inventory score Conclusions and Relevance Both Acupressure arms significantly reduced persistent fatigue compared with usual care, but only relaxing Acupressure had significant effects on sleep quality and quality of life. Relaxing Acupressure offers a possible low-cost option for managing symptoms. Trial Registration clinicaltrials.gov Identifier:NCT01281904

  • feasibility of a randomized controlled trial of self administered Acupressure for symptom management in older adults with knee osteoarthritis
    2016
    Co-Authors: Richard E Harris, Susan L Murphy, Alexander Tsodikov, Laura M Struble
    Abstract:

    Abstract Objectives: To assess the feasibility of a study to evaluate the efficacy of self-administered Acupressure in pain and related symptom management for older people with symptomatic knee osteoarthritis. Feasibility with regard to (1) sample recruitment and retention, (2) treatment fidelity and adherence, and (3) tolerability and adverse events was examined. Methods: The study was a randomized controlled trial. Community-living older adults were recruited and randomly assigned to one of three groups: verum Acupressure, sham Acupressure, and usual care. Participants in the first two groups learned their respective Acupressure protocol during their first center visit and from a set of materials. They were asked to practice the protocol at home once daily, 5 days a week, for 8 weeks. Participants attended three center visits and received weekly phone calls from a research assistant in an 8-week study period. Both quantitative and qualitative data collected from center visits and weekly phone calls were...

D M Thys - One of the best experts on this subject based on the ideXlab platform.

  • Acupressure versus intravenous metoclopramide to prevent nausea and vomiting during spinal anesthesia for cesarean section
    1997
    Co-Authors: Deborah J Stein, David J Birnbach, Brett I Danzer, Maxine M Kuroda, Amos Grunebaum, D M Thys
    Abstract:

    Nausea and vomiting occur frequently during cesarean section under spinal anesthesia. Metoclopramide reduces intraoperative nausea and vomiting, but not without potential side effects. Acupressure, a noninvasive variation of acupuncture that involves constant pressure on the wrist, has been suggested as an alternative method to prevent nausea and vomiting. The aim of this study was to compare Acupressure and intravenous (IV) metoclopramide for the prevention of nausea and vomiting during elective cesarean section under spinal anesthesia. Seventy-five patients were studied in a randomized, prospective, double-blind comparative trial. Group I patients received Acupressure bands + 2 mLIV saline, Group II patients received placebo wrist bands + 10 mg IV metoclopramide, and Group III patients received placebo wrist bands + 2 mL IV saline. Patients who received either Acupressure or metoclopramide prior to initiation of spinal anesthesia for cesarean section had much less nausea than patients in the placebo group. Acupressure is an effective, non-pharmacologic method to reduce intraoperative nausea during elective cesarean section in the awake patient.

  • Acupressure versus intravenous metoclopramide to prevent nausea and vomiting during spinal anesthesia for cesarean section
    1997
    Co-Authors: Deborah J Stein, David J Birnbach, Brett I Danzer, Maxine M Kuroda, Amos Grunebaum, D M Thys
    Abstract:

    Nausea and vomiting occur frequently during cesarean section under spinal anesthesia.Metoclopramide reduces intraoperative nausea and vomiting, but not without potential side effects. Acupressure, a noninvasive variation of acupuncture that involves constant pressure on the wrist, has been suggested as an alternative method to prevent nausea and vomiting. The aim of this study was to compare Acupressure and intravenous (IV) metoclopramide for the prevention of nausea and vomiting during elective cesarean section under spinal anesthesia. Seventy-five patients were studied in a randomized, prospective, double-blind comparative trial. Group I patients received Acupressure bands + 2 mL IV saline, Group II patients received placebo wrist bands + 10 mg IV metoclopramide, and Group III patients received placebo wrist bands + 2 mL IV saline. Patients who received either Acupressure or metoclopramide prior to initiation of spinal anesthesia for cesarean section had much less nausea than patients in the placebo group. Acupressure is an effective, nonpharmacologic method to reduce intraoperative nausea during elective cesarean section in the awake patient. (Anesth Analg 1997;84:342-5)

Kambu Irwan - One of the best experts on this subject based on the ideXlab platform.

  • Terapi Akupresur Sebagai Evidance Based Nursing Untuk Mengurangi Nyeri Dada Pada Pasien Sindrome Koroner Akut
    2020
    Co-Authors: Kambu Irwan
    Abstract:

    Coronary heart disease is clinically characterized by chest pain due to a blockage in the coronary arteries. Acupressure is part of complementary therapy that is able to increase endorphin levels to stimulate pain reduction. The implementation of evidence based nursing Acupressure was given to 8 patients with a purposive sampling technique. The application instrument uses a visual analog pain scale rating scale. The application of Acupressure was given for 20 minutes at the L14 Acupressure point with a pain scale of 0 to 5. The results of the 8 samples given Acupressure all patients experienced a decrease in pain scale. Emphasis or touch on the Acupressure point can increase blood and systemic endorphin levels. Endorphins are the body's opiates naturally produced by the pituitary gland which are useful for reducing pain, affecting memory and mood which will then relax. Acupressure therapy has been proven to reduce pain so it is useful to apply to acute coronary syndrome patients with chest pain.  

  • TERAPI AKUPRESUR SEBAGAI EVIDENCE BASED NURSING UNTUK MENGURANGI NYERI DADA PADA PASIEN SINDROM KORONER AKUT
    2020
    Co-Authors: Kambu Irwan
    Abstract:

    Abstrak Penyakit jantung koroner secara klinis ditandai dengan nyeri dada akibat sumbatan di arteri coroner. Akupresur merupakan bagian terapi komplementer yang mampu meningkatkan kadar endorfin untuk merangsang penurunan nyeri. Pelaksanaan evidence based nursing akupresur ini diberikan pada 8 pasien dengan teknik pemilihan purposive sampling. Instrument penerapan menggunakan skala penilaian nyeri visual analog scale. Penerapan akupresur diberikan selama 20 menit pada titik akupresur L14 dengan skala nyeri 0 sampai 5. Hasil dari 8 sampel yang diberikan akupresur semua pasien mengalami penurunan skala nyeri. Penekanan atau sentuhan pada titik akupresur dapat meningkatkan kadar endorfin dalam darah maupun sistemik. Endorfin merupakan opiat tubuh secara alami dihasilkan oleh kelenjar pituitary yang berguna untuk mengurangi nyeri, mempengaruhi memori dan mood yang kemudian akan memberikan perasaan relaks. Terapi akupresur terbukti mampu menurunkan nyeri sehingga bermanfaat untuk diterapkan pada pasien akut koroner sindrom dengan keluhan nyeri dada.   Abstract Coronary heart disease is clinically characterized by chest pain due to a blockage in the coronary arteries. Acupressure is part of complementary therapy that is able to increase endorphin levels to stimulate pain reduction. The implementation of evidence based nursing Acupressure was given to 8 patients with a purposive sampling technique. The application instrument uses a visual analog pain scale rating scale. The application of Acupressure was given for 20 minutes at the L14 Acupressure point with a pain scale of 0 to 5. The results of the 8 samples given Acupressure all patients experienced a decrease in pain scale. Emphasis or touch on the Acupressure point can increase blood and systemic endorphin levels. Endorphins are the body's opiates naturally produced by the pituitary gland which are useful for reducing pain, affecting memory and mood which will then relax. Acupressure therapy has been proven to reduce pain so it is useful to apply to acute coronary syndrome patients with chest pain.