Acupuncture Needle

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Jinhuai Liu - One of the best experts on this subject based on the ideXlab platform.

  • amphiphilic functionalized Acupuncture Needle as sers sensor for in situ multiphase detection
    Analytical Chemistry, 2018
    Co-Authors: Binbin Zhou, Xiaomin Cao, Xianghu Tang, Liangbao Yang, Mei Mao, Dongyue Lin, Jinhuai Liu
    Abstract:

    Surface enhanced Raman spectroscopy (SERS) is a powerful spectroscopic technique with unique vibrational fingerprints, making it an ideal candidate for in situ multiphase detection. However, it is a great challenge to determine how to guide the SERS sensor to target molecules of interest in multiphase heterogeneous samples with minimal disturbance. Here, we present a portable ultrasensitive and highly repeatable SERS sensor for in situ multiphase detection. The sensor is composed of commercial Ag Acupuncture Needle and PVP-Au nanoparticles (Au NPs). The PVP on the Au NPs can adsorb and induce the Au NPs into a highly uniform array on the surface of the Ag Needle because of its adhesiveness and steric nature. The Au NPs-Ag Needle system (Au-AgN) holds a huge SERS effect, which is enabled by the multiple plasmonic couplings from particle–film and interparticle. The PVP, as the amphiphilic polymer, promotes the target molecules to adsorb on surface of the Au-AgN whether in the oil phase or in the water phase...

  • Amphiphilic Functionalized Acupuncture Needle as SERS Sensor for In Situ Multiphase Detection
    2018
    Co-Authors: Binbin Zhou, Xiaomin Cao, Xianghu Tang, Liangbao Yang, Mei Mao, Dongyue Lin, Jinhuai Liu
    Abstract:

    Surface enhanced Raman spectroscopy (SERS) is a powerful spectroscopic technique with unique vibrational fingerprints, making it an ideal candidate for in situ multiphase detection. However, it is a great challenge to determine how to guide the SERS sensor to target molecules of interest in multiphase heterogeneous samples with minimal disturbance. Here, we present a portable ultrasensitive and highly repeatable SERS sensor for in situ multiphase detection. The sensor is composed of commercial Ag Acupuncture Needle and PVP-Au nanoparticles (Au NPs). The PVP on the Au NPs can adsorb and induce the Au NPs into a highly uniform array on the surface of the Ag Needle because of its adhesiveness and steric nature. The Au NPs-Ag Needle system (Au-AgN) holds a huge SERS effect, which is enabled by the multiple plasmonic couplings from particle–film and interparticle. The PVP, as the amphiphilic polymer, promotes the target molecules to adsorb on surface of the Au-AgN whether in the oil phase or in the water phase. In this work, the Au-AgN sensor was directly inserted into the multiphase system with the laser in situ detection, and SERS detection at different spots of the Au-AgN sensor provided Raman signal of targets molecule in the different phase. In situ multiphase detection can minimize the disturbance of sampling and provide more accurate information. The facile fabrication and amphiphilic functionalization make Au-AgN sensor as generalized SERS detection platform for on-site testing of aqueous samples, organic samples, even the multiphase heterogeneous samples

  • functionalized Acupuncture Needle as surface enhanced resonance raman spectroscopy sensor for rapid and sensitive detection of dopamine in serum and cerebrospinal fluid
    Chemistry: A European Journal, 2017
    Co-Authors: Binbin Zhou, Xiaomin Cao, Xianghu Tang, Liangbao Yang, Jinhuai Liu
    Abstract:

    It is a challenge to develop a robust sensor for simple, rapid operation and sensitive detection of neurotransmitters in complex specimens. Herein, ferric citrate functionalized gold nanoparticles (CA-FeIII /Au NPs) are utilized to develop a facile sensor based on surface-enhanced resonance Raman spectroscopy (SERRS) for sensitive detection of dopamine (DA). The sensor is prepared by decorating the Acupuncture Needle with Au NPs, which enables sufficient surface-enhanced Raman spectroscopy enhancement. The CA-FeIII structure is highly sensitive and selective for DA due to the formation of the CA-FeIII -DA resonant structure; this indicates the advantages of capturing, carrying, and separating DA molecules from complicated samples in a simple operation. Furthermore, the practical application of the fabricated sensor is validated by the detection of DA in pretreated serum and cerebrospinal fluid of Acupuncture-treated mice with detection limits of 0.1 and 2.5 nm DA, respectively. The developed active Acupuncture Needle sensor has potential benefits for sensitive detection and qualitative identification of DA molecules from biological samples.

Binbin Zhou - One of the best experts on this subject based on the ideXlab platform.

  • amphiphilic functionalized Acupuncture Needle as sers sensor for in situ multiphase detection
    Analytical Chemistry, 2018
    Co-Authors: Binbin Zhou, Xiaomin Cao, Xianghu Tang, Liangbao Yang, Mei Mao, Dongyue Lin, Jinhuai Liu
    Abstract:

    Surface enhanced Raman spectroscopy (SERS) is a powerful spectroscopic technique with unique vibrational fingerprints, making it an ideal candidate for in situ multiphase detection. However, it is a great challenge to determine how to guide the SERS sensor to target molecules of interest in multiphase heterogeneous samples with minimal disturbance. Here, we present a portable ultrasensitive and highly repeatable SERS sensor for in situ multiphase detection. The sensor is composed of commercial Ag Acupuncture Needle and PVP-Au nanoparticles (Au NPs). The PVP on the Au NPs can adsorb and induce the Au NPs into a highly uniform array on the surface of the Ag Needle because of its adhesiveness and steric nature. The Au NPs-Ag Needle system (Au-AgN) holds a huge SERS effect, which is enabled by the multiple plasmonic couplings from particle–film and interparticle. The PVP, as the amphiphilic polymer, promotes the target molecules to adsorb on surface of the Au-AgN whether in the oil phase or in the water phase...

  • Amphiphilic Functionalized Acupuncture Needle as SERS Sensor for In Situ Multiphase Detection
    2018
    Co-Authors: Binbin Zhou, Xiaomin Cao, Xianghu Tang, Liangbao Yang, Mei Mao, Dongyue Lin, Jinhuai Liu
    Abstract:

    Surface enhanced Raman spectroscopy (SERS) is a powerful spectroscopic technique with unique vibrational fingerprints, making it an ideal candidate for in situ multiphase detection. However, it is a great challenge to determine how to guide the SERS sensor to target molecules of interest in multiphase heterogeneous samples with minimal disturbance. Here, we present a portable ultrasensitive and highly repeatable SERS sensor for in situ multiphase detection. The sensor is composed of commercial Ag Acupuncture Needle and PVP-Au nanoparticles (Au NPs). The PVP on the Au NPs can adsorb and induce the Au NPs into a highly uniform array on the surface of the Ag Needle because of its adhesiveness and steric nature. The Au NPs-Ag Needle system (Au-AgN) holds a huge SERS effect, which is enabled by the multiple plasmonic couplings from particle–film and interparticle. The PVP, as the amphiphilic polymer, promotes the target molecules to adsorb on surface of the Au-AgN whether in the oil phase or in the water phase. In this work, the Au-AgN sensor was directly inserted into the multiphase system with the laser in situ detection, and SERS detection at different spots of the Au-AgN sensor provided Raman signal of targets molecule in the different phase. In situ multiphase detection can minimize the disturbance of sampling and provide more accurate information. The facile fabrication and amphiphilic functionalization make Au-AgN sensor as generalized SERS detection platform for on-site testing of aqueous samples, organic samples, even the multiphase heterogeneous samples

  • functionalized Acupuncture Needle as surface enhanced resonance raman spectroscopy sensor for rapid and sensitive detection of dopamine in serum and cerebrospinal fluid
    Chemistry: A European Journal, 2017
    Co-Authors: Binbin Zhou, Xiaomin Cao, Xianghu Tang, Liangbao Yang, Jinhuai Liu
    Abstract:

    It is a challenge to develop a robust sensor for simple, rapid operation and sensitive detection of neurotransmitters in complex specimens. Herein, ferric citrate functionalized gold nanoparticles (CA-FeIII /Au NPs) are utilized to develop a facile sensor based on surface-enhanced resonance Raman spectroscopy (SERRS) for sensitive detection of dopamine (DA). The sensor is prepared by decorating the Acupuncture Needle with Au NPs, which enables sufficient surface-enhanced Raman spectroscopy enhancement. The CA-FeIII structure is highly sensitive and selective for DA due to the formation of the CA-FeIII -DA resonant structure; this indicates the advantages of capturing, carrying, and separating DA molecules from complicated samples in a simple operation. Furthermore, the practical application of the fabricated sensor is validated by the detection of DA in pretreated serum and cerebrospinal fluid of Acupuncture-treated mice with detection limits of 0.1 and 2.5 nm DA, respectively. The developed active Acupuncture Needle sensor has potential benefits for sensitive detection and qualitative identification of DA molecules from biological samples.

Younbyoung Chae - One of the best experts on this subject based on the ideXlab platform.

  • Decoding spatial location of perceived pain to Acupuncture Needle using multivoxel pattern analysis
    Molecular Pain, 2019
    Co-Authors: Won Mo Jung, Hi-joon Park, In-seon Lee, Christian Wallraven, Ye Seul Lee, Junsuk Kim, Younbyoung Chae
    Abstract:

    The present study applied multivoxel pattern analysis to decode spatial discrimination in pain perception to Acupuncture Needle from brain functional magnetic resonance image. Fourteen participants...

  • Decoding spatial location of perceived pain to Acupuncture Needle using multivoxel pattern analysis
    SAGE PUBLICATIONS INC, 2019
    Co-Authors: Won Mo Jung, Hi-joon Park, In-seon Lee, Christian Wallraven, Ye Seul Lee, Junsuk Kim, Younbyoung Chae
    Abstract:

    Abstract The present study applied multivoxel pattern analysis to decode spatial discrimination in pain perception to Acupuncture Needle from brain functional magnetic resonance image. Fourteen participants were stimulated by Acupuncture Needles at two adjacent body parts on their left forearm (PC6 vs. HT7). We trained support vector machines on the spatial information from the whole-brain functional magnetic resonance imaging data and projected the support vector machine weight to the brain image space to represent the effect of each voxel on the classifier output. Using region-of-interest masks in individual brains, we trained and tested a linear support vector machine classifier on the accuracy of spatial discrimination in trial-wise functional magnetic resonance imaging data. A classical univariate general linear model analysis testing for differences between the two different locations did not reveal any significant differences. Multivoxel pattern analysis revealed that the brain regions for the prediction of sensory discrimination in pain perceptions to two different points were in the primary somatosensory cortex, primary motor cortex, and supramarginal gyrus, anterior and posterior insula, anterior and posterior cingulate cortex, ventromedial prefrontal cortex, and inferior parietal lobule. Our findings suggest that spatial localizations of pain perceptions to Acupuncture Needle can be predicted by the neural response patterns in the somatosensory areas and the frontoparietal areas. C. The Author(s) 201

  • Sensorimotor Learning of Acupuncture Needle Manipulation Using Visual Feedback
    PLOS ONE, 2015
    Co-Authors: Won Mo Jung, Hi-joon Park, Jinwoong Lim, In-seon Lee, Christian Wallraven, Younbyoung Chae
    Abstract:

    Objective Humans can acquire a wide variety of motor skills using sensory feedback pertaining to discrepancies between intended and actual movements. Acupuncture Needle manipulation involves sophisticated hand movements and represents a fundamental skill for acupuncturists. We investigated whether untrained students could improve their motor performance during Acupuncture Needle manipulation using visual feedback (VF). Methods Twenty-one untrained medical students were included, randomly divided into concurrent (n = 10) and post-trial (n = 11) VF groups. Both groups were trained in simple lift/thrusting techniques during session 1, and in complicated lift/thrusting techniques in session 2 (eight training trials per session). We compared the motion patterns and error magnitudes of pre- and post-training tests. Results During motion pattern analysis, both the concurrent and post-trial VF groups exhibited greater improvements in motion patterns during the complicated lifting/thrusting session. In the magnitude error analysis, both groups also exhibited reduced error magnitudes during the simple lifting/thrusting session. For the training period, the concurrent VF group exhibited reduced error magnitudes across all training trials, whereas the post-trial VF group was characterized by greater error magnitudes during initial trials, which gradually reduced during later trials. Conclusions Our findings suggest that novices can improve the sophisticated hand movements required for Acupuncture Needle manipulation using sensorimotor learning with VF. Use of two types of VF can be beneficial for untrained students in terms of learning how to manipulate Acupuncture Needles, using either automatic or cognitive processes.

  • decreased peripheral and central responses to Acupuncture stimulation following modification of body ownership
    PLOS ONE, 2014
    Co-Authors: Hi-joon Park, Won Mo Jung, Younbyoung Chae, Dong-seon Chang, Vitaly Napadow, Christian Wallraven
    Abstract:

    Acupuncture stimulation increases local blood flow around the site of stimulation and induces signal changes in brain regions related to the body matrix. The rubber hand illusion (RHI) is an experimental paradigm that manipulates important aspects of bodily self-awareness. The present study aimed to investigate how modifications of body ownership using the RHI affect local blood flow and cerebral responses during Acupuncture Needle stimulation. During the RHI, Acupuncture Needle stimulation was applied to the real left hand while measuring blood microcirculation with a LASER Doppler imager (Experiment 1, N=28) and concurrent brain signal changes using functional magnetic resonance imaging (fMRI; Experiment 2, N=17). When the body ownership of participants was altered by the RHI, Acupuncture stimulation resulted in a significantly lower increase in local blood flow (Experiment 1), and significantly less brain activation was detected in the right insula (Experiment 2). This study found changes in both local blood flow and brain responses during Acupuncture Needle stimulation following modification of body ownership. These findings suggest that physiological responses during Acupuncture stimulation can be influenced by the modification of body ownership.

  • haptic simulation for Acupuncture Needle manipulation
    Journal of Alternative and Complementary Medicine, 2014
    Co-Authors: In-seon Lee, Hi-joon Park, Hyangsook Lee, Christian Wallraven, Younbyoung Chae, Hyejung Lee, Taehyung Lee, Woo Chul Shin
    Abstract:

    Abstract Background: Stimulation degree, biomechanical force, and de qi sensation are the three major components of Needle manipulation. To date, it has been difficult to measure all three components quantitatively. Objectives: To (1) measure and compare biomechanical forces of six human acupoints in vivo during haptic manipulation, (2) develop phantom acupoints with biomechanical forces similar to those of human acupoints, and (3) validate the newly developed phantom acupoints based on assessment by doctors of Korean medicine. Methods: The biomechanical force and Needle grasp sensation (i.e., the practitioner's de qi sensation) of six human acupoints (LI4, LI11, LR3, ST36, ST25, and BL25) were assessed in 16 participants upon stimulation with the twisting manipulation technique. On the basis of biomechanical data from these human acupoints, phantom acupoints that generated similar biomechanical forces were developed by using 1%–7% agarose gel. Results: In humans, the mean torque amplitudes of the six acu...

Xianghu Tang - One of the best experts on this subject based on the ideXlab platform.

  • amphiphilic functionalized Acupuncture Needle as sers sensor for in situ multiphase detection
    Analytical Chemistry, 2018
    Co-Authors: Binbin Zhou, Xiaomin Cao, Xianghu Tang, Liangbao Yang, Mei Mao, Dongyue Lin, Jinhuai Liu
    Abstract:

    Surface enhanced Raman spectroscopy (SERS) is a powerful spectroscopic technique with unique vibrational fingerprints, making it an ideal candidate for in situ multiphase detection. However, it is a great challenge to determine how to guide the SERS sensor to target molecules of interest in multiphase heterogeneous samples with minimal disturbance. Here, we present a portable ultrasensitive and highly repeatable SERS sensor for in situ multiphase detection. The sensor is composed of commercial Ag Acupuncture Needle and PVP-Au nanoparticles (Au NPs). The PVP on the Au NPs can adsorb and induce the Au NPs into a highly uniform array on the surface of the Ag Needle because of its adhesiveness and steric nature. The Au NPs-Ag Needle system (Au-AgN) holds a huge SERS effect, which is enabled by the multiple plasmonic couplings from particle–film and interparticle. The PVP, as the amphiphilic polymer, promotes the target molecules to adsorb on surface of the Au-AgN whether in the oil phase or in the water phase...

  • Amphiphilic Functionalized Acupuncture Needle as SERS Sensor for In Situ Multiphase Detection
    2018
    Co-Authors: Binbin Zhou, Xiaomin Cao, Xianghu Tang, Liangbao Yang, Mei Mao, Dongyue Lin, Jinhuai Liu
    Abstract:

    Surface enhanced Raman spectroscopy (SERS) is a powerful spectroscopic technique with unique vibrational fingerprints, making it an ideal candidate for in situ multiphase detection. However, it is a great challenge to determine how to guide the SERS sensor to target molecules of interest in multiphase heterogeneous samples with minimal disturbance. Here, we present a portable ultrasensitive and highly repeatable SERS sensor for in situ multiphase detection. The sensor is composed of commercial Ag Acupuncture Needle and PVP-Au nanoparticles (Au NPs). The PVP on the Au NPs can adsorb and induce the Au NPs into a highly uniform array on the surface of the Ag Needle because of its adhesiveness and steric nature. The Au NPs-Ag Needle system (Au-AgN) holds a huge SERS effect, which is enabled by the multiple plasmonic couplings from particle–film and interparticle. The PVP, as the amphiphilic polymer, promotes the target molecules to adsorb on surface of the Au-AgN whether in the oil phase or in the water phase. In this work, the Au-AgN sensor was directly inserted into the multiphase system with the laser in situ detection, and SERS detection at different spots of the Au-AgN sensor provided Raman signal of targets molecule in the different phase. In situ multiphase detection can minimize the disturbance of sampling and provide more accurate information. The facile fabrication and amphiphilic functionalization make Au-AgN sensor as generalized SERS detection platform for on-site testing of aqueous samples, organic samples, even the multiphase heterogeneous samples

  • functionalized Acupuncture Needle as surface enhanced resonance raman spectroscopy sensor for rapid and sensitive detection of dopamine in serum and cerebrospinal fluid
    Chemistry: A European Journal, 2017
    Co-Authors: Binbin Zhou, Xiaomin Cao, Xianghu Tang, Liangbao Yang, Jinhuai Liu
    Abstract:

    It is a challenge to develop a robust sensor for simple, rapid operation and sensitive detection of neurotransmitters in complex specimens. Herein, ferric citrate functionalized gold nanoparticles (CA-FeIII /Au NPs) are utilized to develop a facile sensor based on surface-enhanced resonance Raman spectroscopy (SERRS) for sensitive detection of dopamine (DA). The sensor is prepared by decorating the Acupuncture Needle with Au NPs, which enables sufficient surface-enhanced Raman spectroscopy enhancement. The CA-FeIII structure is highly sensitive and selective for DA due to the formation of the CA-FeIII -DA resonant structure; this indicates the advantages of capturing, carrying, and separating DA molecules from complicated samples in a simple operation. Furthermore, the practical application of the fabricated sensor is validated by the detection of DA in pretreated serum and cerebrospinal fluid of Acupuncture-treated mice with detection limits of 0.1 and 2.5 nm DA, respectively. The developed active Acupuncture Needle sensor has potential benefits for sensitive detection and qualitative identification of DA molecules from biological samples.

Xiaomin Cao - One of the best experts on this subject based on the ideXlab platform.

  • amphiphilic functionalized Acupuncture Needle as sers sensor for in situ multiphase detection
    Analytical Chemistry, 2018
    Co-Authors: Binbin Zhou, Xiaomin Cao, Xianghu Tang, Liangbao Yang, Mei Mao, Dongyue Lin, Jinhuai Liu
    Abstract:

    Surface enhanced Raman spectroscopy (SERS) is a powerful spectroscopic technique with unique vibrational fingerprints, making it an ideal candidate for in situ multiphase detection. However, it is a great challenge to determine how to guide the SERS sensor to target molecules of interest in multiphase heterogeneous samples with minimal disturbance. Here, we present a portable ultrasensitive and highly repeatable SERS sensor for in situ multiphase detection. The sensor is composed of commercial Ag Acupuncture Needle and PVP-Au nanoparticles (Au NPs). The PVP on the Au NPs can adsorb and induce the Au NPs into a highly uniform array on the surface of the Ag Needle because of its adhesiveness and steric nature. The Au NPs-Ag Needle system (Au-AgN) holds a huge SERS effect, which is enabled by the multiple plasmonic couplings from particle–film and interparticle. The PVP, as the amphiphilic polymer, promotes the target molecules to adsorb on surface of the Au-AgN whether in the oil phase or in the water phase...

  • Amphiphilic Functionalized Acupuncture Needle as SERS Sensor for In Situ Multiphase Detection
    2018
    Co-Authors: Binbin Zhou, Xiaomin Cao, Xianghu Tang, Liangbao Yang, Mei Mao, Dongyue Lin, Jinhuai Liu
    Abstract:

    Surface enhanced Raman spectroscopy (SERS) is a powerful spectroscopic technique with unique vibrational fingerprints, making it an ideal candidate for in situ multiphase detection. However, it is a great challenge to determine how to guide the SERS sensor to target molecules of interest in multiphase heterogeneous samples with minimal disturbance. Here, we present a portable ultrasensitive and highly repeatable SERS sensor for in situ multiphase detection. The sensor is composed of commercial Ag Acupuncture Needle and PVP-Au nanoparticles (Au NPs). The PVP on the Au NPs can adsorb and induce the Au NPs into a highly uniform array on the surface of the Ag Needle because of its adhesiveness and steric nature. The Au NPs-Ag Needle system (Au-AgN) holds a huge SERS effect, which is enabled by the multiple plasmonic couplings from particle–film and interparticle. The PVP, as the amphiphilic polymer, promotes the target molecules to adsorb on surface of the Au-AgN whether in the oil phase or in the water phase. In this work, the Au-AgN sensor was directly inserted into the multiphase system with the laser in situ detection, and SERS detection at different spots of the Au-AgN sensor provided Raman signal of targets molecule in the different phase. In situ multiphase detection can minimize the disturbance of sampling and provide more accurate information. The facile fabrication and amphiphilic functionalization make Au-AgN sensor as generalized SERS detection platform for on-site testing of aqueous samples, organic samples, even the multiphase heterogeneous samples

  • functionalized Acupuncture Needle as surface enhanced resonance raman spectroscopy sensor for rapid and sensitive detection of dopamine in serum and cerebrospinal fluid
    Chemistry: A European Journal, 2017
    Co-Authors: Binbin Zhou, Xiaomin Cao, Xianghu Tang, Liangbao Yang, Jinhuai Liu
    Abstract:

    It is a challenge to develop a robust sensor for simple, rapid operation and sensitive detection of neurotransmitters in complex specimens. Herein, ferric citrate functionalized gold nanoparticles (CA-FeIII /Au NPs) are utilized to develop a facile sensor based on surface-enhanced resonance Raman spectroscopy (SERRS) for sensitive detection of dopamine (DA). The sensor is prepared by decorating the Acupuncture Needle with Au NPs, which enables sufficient surface-enhanced Raman spectroscopy enhancement. The CA-FeIII structure is highly sensitive and selective for DA due to the formation of the CA-FeIII -DA resonant structure; this indicates the advantages of capturing, carrying, and separating DA molecules from complicated samples in a simple operation. Furthermore, the practical application of the fabricated sensor is validated by the detection of DA in pretreated serum and cerebrospinal fluid of Acupuncture-treated mice with detection limits of 0.1 and 2.5 nm DA, respectively. The developed active Acupuncture Needle sensor has potential benefits for sensitive detection and qualitative identification of DA molecules from biological samples.