The Experts below are selected from a list of 306 Experts worldwide ranked by ideXlab platform

Susan K. Pingleton - One of the best experts on this subject based on the ideXlab platform.

  • Acute Respiratory Failure in chronic obstructive pulmonary disease.
    Current opinion in pulmonary medicine, 1996
    Co-Authors: Susan K. Pingleton
    Abstract:

    Clinically significant chronic obstructive pulmonary disease is a common and important disorder in the United States. As many as 15 million individuals suffer from chronic obstructive pulmonary disease, many of whom have disease requiring hospital or ICU admission. Acute Respiratory Failure in patients with chronic obstructive pulmonary disease is one of the most common causes of admission to the ICU for this patient population. In this article I address common issues regarding diagnosis and management of Acute Respiratory Failure in chronic obstructive pulmonary disease. Acute Respiratory Failure will be defined as well as the common and unusual etiologies of Acute Respiratory Failure. Pharmacologic and nonpharmacologic treatment will be addressed, especially the ventilatory treatment of the intubated patient with chronic obstructive pulmonary disease. Special attention has been made to included the most recent investigations regarding diagnosis and treatment of the patient with chronic obstructive pulmonary disease and Respiratory Failure.

Lena M. Napolitano - One of the best experts on this subject based on the ideXlab platform.

  • Postoperative pulmonary complications: pneumonia and Acute Respiratory Failure.
    The Surgical clinics of North America, 2012
    Co-Authors: Gaurav Sachdev, Lena M. Napolitano
    Abstract:

    Postoperative pulmonary complications (atelectasis, pneumonia, pulmonary edema, Acute Respiratory Failure) are common, particularly after abdominal and thoracic surgery, pneumonia and atelectasis being the most common. Postoperative pneumonia is associated with increased morbidity, length of hospital stay, and costs. Few institutions have pneumonia prevention programs for surgical patients, and these should be strongly considered. Acute Respiratory Failure is a life-threatening pulmonary complication that requires institution of mechanical ventilation and admission to the intensive care unit, and is associated with increased risk for ventilator-associated pneumonia. This article discusses epidemiology, risk factors, diagnosis, treatment, and prevention of these pulmonary complications in surgical patients.

Elie Azoulay - One of the best experts on this subject based on the ideXlab platform.

  • Acute Respiratory Failure in immunocompromised adults
    The Lancet. Respiratory medicine, 2018
    Co-Authors: Elie Azoulay, Djamel Mokart, Achille Kouatchet, Alexandre Demoule, Virginie Lemiale
    Abstract:

    Summary Acute Respiratory Failure occurs in up to half of patients with haematological malignancies and 15% of those with solid tumours or solid organ transplantation. Mortality remains high. Factors associated with mortality include a need for invasive mechanical ventilation, organ dysfunction, older age, frailty or poor performance status, delayed intensive care unit admission, and Acute Respiratory Failure due to an invasive fungal infection or unknown cause. In addition to appropriate antibacterial therapy, initial clinical management aims to restore oxygenation and predict the most probable cause based on variables related to the underlying disease, Acute Respiratory Failure characteristics, and radiographic findings. The cause of Acute Respiratory Failure must then be confirmed using the most efficient, least invasive, and safest diagnostic tests. In patients with Acute Respiratory Failure of undetermined cause, a standardised diagnostic investigation should be done immediately at admission before deciding whether to perform more invasive diagnostic procedures or to start empirical treatments. Collaborative and multidisciplinary clinical and research networks are crucial to improve our understanding of disease pathogenesis and causation and to develop less invasive diagnostic strategies and more targeted treatment options.

  • Acute Respiratory Failure in Patients with Hematologic Malignancies
    Clinics in chest medicine, 2017
    Co-Authors: Anne-sophie Moreau, Virginie Lemiale, Olivier Peyrony, Lara Zafrani, Elie Azoulay
    Abstract:

    Acute Respiratory Failure occurs in up to 50% of patients treated for hematologic malignancies and is associated with a high case fatality rate. Because of residual organ dysfunction and time spent receiving Respiratory care, underlying disease control is affected. Early admission to an intensive care unit for Acute Respiratory Failure has proven benefit because it is the best place for rapid implementation of noninvasive diagnostic and therapeutic strategies. This article reviews the clinical approach and diagnostic strategies for Acute Respiratory Failure in patients with hematologic malignancies.

  • Burden of Respiratory viruses in patients with Acute Respiratory Failure.
    Journal of medical virology, 2013
    Co-Authors: David Schnell, Elie Azoulay, Virginie Lemiale, Maud Gits-muselli, Emmanuel Canet, Benoit Schlemmer, François Simon, Jérôme Legoff
    Abstract:

    Respiratory viruses (RVs) are ubiquitous pathogens that represent a major cause of community-acquired pneumonia and chronic pulmonary diseases exacerbations. However, their contribution to Acute Respiratory Failure events requiring intensive care unit admission in the era of rapid multiplex molecular assay deserves further evaluation. This study investigated the burden of viral infections in non immunocompromised patients admitted to the intensive care unit for Acute Respiratory Failure using a multiplex molecular assay. Patients were investigated for RVs using immunofluoresence testing and a commercial multiplex molecular assay, and for bacteria using conventional culture. Half the patients (34/70, 49%) had a documented RVs infection. No other pathogen was found in 24 (71%) patients. Viral infection was detected more frequently in patients with obstructive Respiratory diseases (64% vs. 29%; P = 0.0075). Multiplex molecular assay should be considered as an usefull diagnostic tool in patients admitted to the intensive care unit with Acute Respiratory Failure, especially those with Acute exacerbations of chronic obstructive pulmonary disease and asthma. J. Med. Virol. 86:1198–1202, 2014. © 2013 Wiley Periodicals, Inc.

William A. Whitelaw - One of the best experts on this subject based on the ideXlab platform.

  • Management of Acute Respiratory Failure in chronic obstructive pulmonary disease.
    Current opinion in pulmonary medicine, 1997
    Co-Authors: Danny J. Zuege, William A. Whitelaw
    Abstract:

    Acute Respiratory Failure in the setting of preexisting chronic obstructive pulmonary disease (COPD) is a common reason for hospitalization and results in the consumption of a substantial amount of health care resources. In recent years, new therapies have been proposed, and new information about older therapies has become available. Noninvasive ventilation is finding an important place as a means of avoiding tracheal intubation. The role of bacterial infection as a frequent precipitant to Acute Respiratory Failure in COPD remains poorly defined and presumptive antibiotic therapy remains controversial. Vasodilators of the pulmonary circulation have received much attention but so far have been disappointing in this situation. The role of several other traditional therapies, such as mucolytics and methods of secretion removal, have also been challenged in recent years. In this review we focus or recent advances in the assessment and management of Acute Respiratory Failure in the setting of pre-existing COPD.

Virginie Lemiale - One of the best experts on this subject based on the ideXlab platform.

  • Acute Respiratory Failure in immunocompromised adults
    The Lancet. Respiratory medicine, 2018
    Co-Authors: Elie Azoulay, Djamel Mokart, Achille Kouatchet, Alexandre Demoule, Virginie Lemiale
    Abstract:

    Summary Acute Respiratory Failure occurs in up to half of patients with haematological malignancies and 15% of those with solid tumours or solid organ transplantation. Mortality remains high. Factors associated with mortality include a need for invasive mechanical ventilation, organ dysfunction, older age, frailty or poor performance status, delayed intensive care unit admission, and Acute Respiratory Failure due to an invasive fungal infection or unknown cause. In addition to appropriate antibacterial therapy, initial clinical management aims to restore oxygenation and predict the most probable cause based on variables related to the underlying disease, Acute Respiratory Failure characteristics, and radiographic findings. The cause of Acute Respiratory Failure must then be confirmed using the most efficient, least invasive, and safest diagnostic tests. In patients with Acute Respiratory Failure of undetermined cause, a standardised diagnostic investigation should be done immediately at admission before deciding whether to perform more invasive diagnostic procedures or to start empirical treatments. Collaborative and multidisciplinary clinical and research networks are crucial to improve our understanding of disease pathogenesis and causation and to develop less invasive diagnostic strategies and more targeted treatment options.

  • Acute Respiratory Failure in Patients with Hematologic Malignancies
    Clinics in chest medicine, 2017
    Co-Authors: Anne-sophie Moreau, Virginie Lemiale, Olivier Peyrony, Lara Zafrani, Elie Azoulay
    Abstract:

    Acute Respiratory Failure occurs in up to 50% of patients treated for hematologic malignancies and is associated with a high case fatality rate. Because of residual organ dysfunction and time spent receiving Respiratory care, underlying disease control is affected. Early admission to an intensive care unit for Acute Respiratory Failure has proven benefit because it is the best place for rapid implementation of noninvasive diagnostic and therapeutic strategies. This article reviews the clinical approach and diagnostic strategies for Acute Respiratory Failure in patients with hematologic malignancies.

  • Burden of Respiratory viruses in patients with Acute Respiratory Failure.
    Journal of medical virology, 2013
    Co-Authors: David Schnell, Elie Azoulay, Virginie Lemiale, Maud Gits-muselli, Emmanuel Canet, Benoit Schlemmer, François Simon, Jérôme Legoff
    Abstract:

    Respiratory viruses (RVs) are ubiquitous pathogens that represent a major cause of community-acquired pneumonia and chronic pulmonary diseases exacerbations. However, their contribution to Acute Respiratory Failure events requiring intensive care unit admission in the era of rapid multiplex molecular assay deserves further evaluation. This study investigated the burden of viral infections in non immunocompromised patients admitted to the intensive care unit for Acute Respiratory Failure using a multiplex molecular assay. Patients were investigated for RVs using immunofluoresence testing and a commercial multiplex molecular assay, and for bacteria using conventional culture. Half the patients (34/70, 49%) had a documented RVs infection. No other pathogen was found in 24 (71%) patients. Viral infection was detected more frequently in patients with obstructive Respiratory diseases (64% vs. 29%; P = 0.0075). Multiplex molecular assay should be considered as an usefull diagnostic tool in patients admitted to the intensive care unit with Acute Respiratory Failure, especially those with Acute exacerbations of chronic obstructive pulmonary disease and asthma. J. Med. Virol. 86:1198–1202, 2014. © 2013 Wiley Periodicals, Inc.