Intensive Care Unit

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Deborah J Cook - One of the best experts on this subject based on the ideXlab platform.

  • thromboprophylaxis in the Intensive Care Unit focus on medical surgical patients
    Critical Care Medicine, 2010
    Co-Authors: Deborah J Cook, Mark Crowther
    Abstract:

    Critically ill patients in the medical-surgical Intensive Care Unit are at high risk for deep venous thrombosis and pulmonary embolism, which comprise venous thromboembolism. Herein, we describe the prevalence, incidence, risk factors, clinical consequences, prophylaxis against venous thromboembolism in critically ill patients, and compliance with thromboprophylaxis. We focus primarily on medical-surgical Intensive Care Unit patients, who represent the largest subgroup of critically ill patients. Despite the large and growing number of critically ill patients in our aging society, their high risk for venous thromboembolism, and the morbidity and mortality associated with this complication of critical illness, relatively few rigorous studies are available. Large, well-designed, randomized trials of thromboprophylaxis, powered to detect differences in patient-important outcomes, are required to advance our understanding and Care of these vulnerable patients. Furthermore, because thromboprophylaxis is a common error of omission in hospitalized patients, redoubled efforts are needed to ensure that it is used in practice.

  • clinician predictions of Intensive Care Unit mortality
    Critical Care Medicine, 2004
    Co-Authors: Graeme Rocker, Deborah J Cook, Mitchell M Levy, Peter Sjokvist, Bruce Weaver, Simon Finfer, Ellen Mcdonald, John C Marshall, Anne Kirby, Peter Dodek
    Abstract:

    Objective:Predicting outcomes for critically ill patients is an important aspect of discussions with families in the Intensive Care Unit. Our objective was to evaluate clinical Intensive Care Unit survival predictions and their consequences for mechanically ventilated patients.Design:Prospective coh

  • impact of a clinical pharmacist in a multidisciplinary Intensive Care Unit
    Critical Care Medicine, 1994
    Co-Authors: Mitra Montazeri, Deborah J Cook
    Abstract:

    ObjectivesTo describe the activities of a clinical Intensive Care Unit (ICU) pharmacist and to determine whether pharmacist-initiated consultations lead to changes in drug costs.DesignProspective, 3-month study.SettingA 15-bed, university-affiliated, tertiary Care medical-surgical ICU.InterventionsT

Maite Garrousteorgeas - One of the best experts on this subject based on the ideXlab platform.

Brahm Goldstein - One of the best experts on this subject based on the ideXlab platform.

  • impact of a pediatric clinical pharmacist in the pediatric Intensive Care Unit
    Critical Care Medicine, 2002
    Co-Authors: Marianne I Krupicka, Karen Sonnenthal, Susan L Bratton, Brahm Goldstein
    Abstract:

    Objective: To study the impact of a clinical pharmacist in a pediatric Intensive Care Unit. The goals of the study were to determine the type and quantity of patient Care interventions recommended by a clinical pharmacist and to specifically examine cost savings (or loss) that resulted from clinical pharmacist recommendations. Design: A prospective case series. Setting: Ten-bed pediatric Intensive Care Unit in a university-affiliated children's hospital. Patients: All patients admitted to the pediatric Intensive Care Unit during the study period. Interventions: None. Measurements and Main Results: During the 24-wk study period, the pediatric clinical pharmacist documented all interventions that occurred during her shift. She rounded with the pediatric Intensive Care Unit team approximately two times a week and reviewed medication lists daily. Drug acquisition costs were used to calculate drug cost savings. Demographic information was collected on all the patients in the pediatric Intensive Care Unit during the study period. There were 35 recommendations per 100 patient days. The most common interventions were dosage changes (28%), drug information (26%), and miscellaneous information (22%). The average time spent per day by the clinical pharmacist in the pediatric Intensive Care Unit was 0.73 hrs or 0.02 full-time equivalent. The total cost direct savings for the study period was $1,977. Extrapolated to direct cost savings per year, the total amount saved was $9,135/year or 0.15 full-time equivalent. Indirect savings from educational activities, avoidance of medication errors, and optimization of medical therapies represent an additional nonquantifiable amount. Conclusion: We conclude that a clinical pharmacist is an important and cost-effective member of the pediatric Intensive Care Unit team.

Youssef Blel - One of the best experts on this subject based on the ideXlab platform.

Eli N Perencevich - One of the best experts on this subject based on the ideXlab platform.

  • impact of admission hyperglycemia on hospital mortality in various Intensive Care Unit populations
    Critical Care Medicine, 2005
    Co-Authors: Brian W Whitcomb, Elizabeth Kimbrough Pradhan, Anastassios G Pittas, Maryclaire Roghmann, Eli N Perencevich
    Abstract:

    Objective: Hyperglycemia in Intensive Care Unit patients has been associated with an increased mortality rate, and institutions have already begun tight glucose control programs based on a limited number of clinical trials in restricted populations. This study aimed to assess the generalizability of the association between hyperglycemia and in-hospital mortality in different Intensive Care Unit types adjusting for illness severity and diabetic history. Design: Retrospective cohort study. Setting: The medical, cardiothoracic surgery, cardiac, general surgical, and neurosurgical Intensive Care Units of the University of Maryland Medical Center. Patients: Patients admitted between July 1996 and January 1998 with length of stay >24 hrs (n 2713). Interventions: On Intensive Care Unit admission, blood glucose and other physiologic variables were evaluated. Regular measurements were taken for calculation of Acute Physiology and Chronic Health Evaluation III scoring. Patients were followed through hospital discharge. Admission blood glucose was used to classify patients as hyperglycemic (>200 mg/dL) or normoglycemic (60 – 200 mg/dL). The contribution of hyperglycemia to in-hospital mortality stratified by Intensive Care Unit type and diabetes history while controlling for illness severity was estimated by logistic regression. Measurements and Main Results: The adjusted odds ratios for death comparing all patients with hyperglycemia to those without were 0.81 (95% confidence interval, 0.37, 1.77) and 1.76 (95% confidence interval, 1.23, 2.53) for those with and without diabetic history, respectively. Higher mortality was seen in hyperglycemic patients without diabetic history in the cardiothoracic, (adjusted odds ratio, 2.84 [1.21, 6.63]), cardiac (adjusted odds ratio, 2.64 [1.14, 6.10]), and neurosurgical Units (adjusted odds ratio, 2.96 [1.51, 5.77]) but not the medical or surgical Intensive Care Units or in patients with diabetic history. Conclusions: The association between hyperglycemia on Intensive Care Unit admission and in-hospital mortality was not uniform in the study population; hyperglycemia was an independent risk factor only in patients without diabetic history in the cardiac, cardiothoracic, and neurosurgical Intensive Care Units. (Crit Care Med 2005; 33:2772–2777)