Scan Science and Technology
Contact Leading Edge Experts & Companies
Adenosine Triphosphatase
The Experts below are selected from a list of 21915 Experts worldwide ranked by ideXlab platform
Reinaldo Marin – One of the best experts on this subject based on the ideXlab platform.
-
preeclampsia lipid peroxidation and calcium Adenosine Triphosphatase activity of red blood cell ghosts
American Journal of Obstetrics and Gynecology, 1998Co-Authors: Rosalia Matteo, Teresa Proverbio, Keyla Cordova, Fulgencio Proverbio, Reinaldo MarinAbstract:Objective: We evaluated the effect of lipid peroxidation on the calcium Adenosine Triphosphatase activity of red blood cell ghosts from normotensive pregnant women and compared it with the Adenosine Triphosphatase activity and lipid peroxidation in preeclampsia. Study Design: Ten nulliparous normotensive and 10 nulliparous preeclamptic pregnant women (38 to 39 weeks of gestation) were used as blood donors. Preeclampsia was diagnosed on the basis of blood pressure (>140/90 mm Hg) and proteinuria (>0.5 gm of urinary protein per day). Red blood cell ghosts were prepared for both groups and used for calcium Adenosine Triphosphatase activity and lipid peroxidation determinations. Control ghosts (normotensive) were irradiated with ultraviolet light for different lengths of time. Results: Calcium Adenosine Triphosphatase activity of red blood cell ghosts from normotensive women is sensitive to lipid peroxidation. The lipid peroxidation of red blood cell ghosts from preeclamptic women is higher than that from normotensive women. Conclusion: The diminution of the calcium Adenosine Triphosphatase activity with preeclampsia could be explained by the sensitivity of this Adenosine Triphosphatase to lipid peroxidation.
-
preeclampsia and calcium Adenosine Triphosphatase activity of red blood cell ghosts
American Journal of Obstetrics and Gynecology, 1994Co-Authors: Gianfranco Nardulli, Reinaldo Marin, Fulgencio Proverbio, Flor Limongi, Teresa ProverbioAbstract:Objective: The current work was undertaken to study the calcium Adenosine Triphosphatase activity of red blood cell membranes from pregnant women with preeclampsia. Study Design: Six normotensive and six preeclamptic pregnant women at 38 to 39 weeks of gestation were studied. The diagnosis of preeclampsia was made on the basis of blood pressure (> 140/90 mm Hg), proteinuria (>0.5 gm of urinary protein per day), or edema. Hemoglobin-free red blood cell ghosts were prepared from the heparinized blood samples and were used to determine the calcium Adenosine Triphosphatase activity. Results: It was found that the calcium Adenosine Triphosphatase activity of preeclamptic women is diminished by about 50% compared with that of normotensive pregnant women. Conclusion: A diminution of the calcium Adenosine Triphosphatase activity of erythrocytes in preeclampsia might be an indication that the in vivo activity of the calcium pump of these cells is diminished, which could, in turn, drive the cells to increase their cytoplasmic free calcium concentration.
Teresa Proverbio – One of the best experts on this subject based on the ideXlab platform.
-
preeclampsia lipid peroxidation and calcium Adenosine Triphosphatase activity of red blood cell ghosts
American Journal of Obstetrics and Gynecology, 1998Co-Authors: Rosalia Matteo, Teresa Proverbio, Keyla Cordova, Fulgencio Proverbio, Reinaldo MarinAbstract:Objective: We evaluated the effect of lipid peroxidation on the calcium Adenosine Triphosphatase activity of red blood cell ghosts from normotensive pregnant women and compared it with the Adenosine Triphosphatase activity and lipid peroxidation in preeclampsia. Study Design: Ten nulliparous normotensive and 10 nulliparous preeclamptic pregnant women (38 to 39 weeks of gestation) were used as blood donors. Preeclampsia was diagnosed on the basis of blood pressure (>140/90 mm Hg) and proteinuria (>0.5 gm of urinary protein per day). Red blood cell ghosts were prepared for both groups and used for calcium Adenosine Triphosphatase activity and lipid peroxidation determinations. Control ghosts (normotensive) were irradiated with ultraviolet light for different lengths of time. Results: Calcium Adenosine Triphosphatase activity of red blood cell ghosts from normotensive women is sensitive to lipid peroxidation. The lipid peroxidation of red blood cell ghosts from preeclamptic women is higher than that from normotensive women. Conclusion: The diminution of the calcium Adenosine Triphosphatase activity with preeclampsia could be explained by the sensitivity of this Adenosine Triphosphatase to lipid peroxidation.
-
preeclampsia and calcium Adenosine Triphosphatase activity of red blood cell ghosts
American Journal of Obstetrics and Gynecology, 1994Co-Authors: Gianfranco Nardulli, Reinaldo Marin, Fulgencio Proverbio, Flor Limongi, Teresa ProverbioAbstract:Objective: The current work was undertaken to study the calcium Adenosine Triphosphatase activity of red blood cell membranes from pregnant women with preeclampsia. Study Design: Six normotensive and six preeclamptic pregnant women at 38 to 39 weeks of gestation were studied. The diagnosis of preeclampsia was made on the basis of blood pressure (> 140/90 mm Hg), proteinuria (>0.5 gm of urinary protein per day), or edema. Hemoglobin-free red blood cell ghosts were prepared from the heparinized blood samples and were used to determine the calcium Adenosine Triphosphatase activity. Results: It was found that the calcium Adenosine Triphosphatase activity of preeclamptic women is diminished by about 50% compared with that of normotensive pregnant women. Conclusion: A diminution of the calcium Adenosine Triphosphatase activity of erythrocytes in preeclampsia might be an indication that the in vivo activity of the calcium pump of these cells is diminished, which could, in turn, drive the cells to increase their cytoplasmic free calcium concentration.
Fulgencio Proverbio – One of the best experts on this subject based on the ideXlab platform.
-
preeclampsia lipid peroxidation and calcium Adenosine Triphosphatase activity of red blood cell ghosts
American Journal of Obstetrics and Gynecology, 1998Co-Authors: Rosalia Matteo, Teresa Proverbio, Keyla Cordova, Fulgencio Proverbio, Reinaldo MarinAbstract:Objective: We evaluated the effect of lipid peroxidation on the calcium Adenosine Triphosphatase activity of red blood cell ghosts from normotensive pregnant women and compared it with the Adenosine Triphosphatase activity and lipid peroxidation in preeclampsia. Study Design: Ten nulliparous normotensive and 10 nulliparous preeclamptic pregnant women (38 to 39 weeks of gestation) were used as blood donors. Preeclampsia was diagnosed on the basis of blood pressure (>140/90 mm Hg) and proteinuria (>0.5 gm of urinary protein per day). Red blood cell ghosts were prepared for both groups and used for calcium Adenosine Triphosphatase activity and lipid peroxidation determinations. Control ghosts (normotensive) were irradiated with ultraviolet light for different lengths of time. Results: Calcium Adenosine Triphosphatase activity of red blood cell ghosts from normotensive women is sensitive to lipid peroxidation. The lipid peroxidation of red blood cell ghosts from preeclamptic women is higher than that from normotensive women. Conclusion: The diminution of the calcium Adenosine Triphosphatase activity with preeclampsia could be explained by the sensitivity of this Adenosine Triphosphatase to lipid peroxidation.
-
preeclampsia and calcium Adenosine Triphosphatase activity of red blood cell ghosts
American Journal of Obstetrics and Gynecology, 1994Co-Authors: Gianfranco Nardulli, Reinaldo Marin, Fulgencio Proverbio, Flor Limongi, Teresa ProverbioAbstract:Objective: The current work was undertaken to study the calcium Adenosine Triphosphatase activity of red blood cell membranes from pregnant women with preeclampsia. Study Design: Six normotensive and six preeclamptic pregnant women at 38 to 39 weeks of gestation were studied. The diagnosis of preeclampsia was made on the basis of blood pressure (> 140/90 mm Hg), proteinuria (>0.5 gm of urinary protein per day), or edema. Hemoglobin-free red blood cell ghosts were prepared from the heparinized blood samples and were used to determine the calcium Adenosine Triphosphatase activity. Results: It was found that the calcium Adenosine Triphosphatase activity of preeclamptic women is diminished by about 50% compared with that of normotensive pregnant women. Conclusion: A diminution of the calcium Adenosine Triphosphatase activity of erythrocytes in preeclampsia might be an indication that the in vivo activity of the calcium pump of these cells is diminished, which could, in turn, drive the cells to increase their cytoplasmic free calcium concentration.