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Adrenal Cortex Carcinoma
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Jean-marc Gallo – One of the best experts on this subject based on the ideXlab platform.
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mutually exclusive expression of βiii tubulin and vimentin in Adrenal Cortex Carcinoma sw13 cells
FEBS Letters, 2000Co-Authors: Rachel Butler, Janice Robertson, Jean-marc GalloAbstract:During embryogenesis, the maturation of neuroblasts into neurones is accompanied by the down-regulation of vimentin and by the expression of neuronal microtubular proteins. Here, we show that human Adrenal Cortex SW13 cells express βIII-tubulin, MAP2b and tau. Analysis of vimentin-positive and -negative subclones of SW13 cells revealed that, under defined cultured conditions, βIII-tubulin and MAP2b were present only in vimentin-deficient cells and that βIII-tubulin repression occurred at the transcriptional level in vimentin-positive cells. These results suggest that vimentin repression and βIII-tubulin expression are co-ordinated by an upstream mechanism relevant to the control of cytoskeletal protein expression during neuronal development.
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Mutually exclusive expression of βIII‐tubulin and vimentin in Adrenal Cortex Carcinoma SW13 cells
FEBS Letters, 2000Co-Authors: Rachel Butler, Janice Robertson, Jean-marc GalloAbstract:During embryogenesis, the maturation of neuroblasts into neurones is accompanied by the down-regulation of vimentin and by the expression of neuronal microtubular proteins. Here, we show that human Adrenal Cortex SW13 cells express βIII-tubulin, MAP2b and tau. Analysis of vimentin-positive and -negative subclones of SW13 cells revealed that, under defined cultured conditions, βIII-tubulin and MAP2b were present only in vimentin-deficient cells and that βIII-tubulin repression occurred at the transcriptional level in vimentin-positive cells. These results suggest that vimentin repression and βIII-tubulin expression are co-ordinated by an upstream mechanism relevant to the control of cytoskeletal protein expression during neuronal development.
Rachel Butler – One of the best experts on this subject based on the ideXlab platform.
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mutually exclusive expression of βiii tubulin and vimentin in Adrenal Cortex Carcinoma sw13 cells
FEBS Letters, 2000Co-Authors: Rachel Butler, Janice Robertson, Jean-marc GalloAbstract:During embryogenesis, the maturation of neuroblasts into neurones is accompanied by the down-regulation of vimentin and by the expression of neuronal microtubular proteins. Here, we show that human Adrenal Cortex SW13 cells express βIII-tubulin, MAP2b and tau. Analysis of vimentin-positive and -negative subclones of SW13 cells revealed that, under defined cultured conditions, βIII-tubulin and MAP2b were present only in vimentin-deficient cells and that βIII-tubulin repression occurred at the transcriptional level in vimentin-positive cells. These results suggest that vimentin repression and βIII-tubulin expression are co-ordinated by an upstream mechanism relevant to the control of cytoskeletal protein expression during neuronal development.
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Mutually exclusive expression of βIII‐tubulin and vimentin in Adrenal Cortex Carcinoma SW13 cells
FEBS Letters, 2000Co-Authors: Rachel Butler, Janice Robertson, Jean-marc GalloAbstract:During embryogenesis, the maturation of neuroblasts into neurones is accompanied by the down-regulation of vimentin and by the expression of neuronal microtubular proteins. Here, we show that human Adrenal Cortex SW13 cells express βIII-tubulin, MAP2b and tau. Analysis of vimentin-positive and -negative subclones of SW13 cells revealed that, under defined cultured conditions, βIII-tubulin and MAP2b were present only in vimentin-deficient cells and that βIII-tubulin repression occurred at the transcriptional level in vimentin-positive cells. These results suggest that vimentin repression and βIII-tubulin expression are co-ordinated by an upstream mechanism relevant to the control of cytoskeletal protein expression during neuronal development.
Janice Robertson – One of the best experts on this subject based on the ideXlab platform.
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mutually exclusive expression of βiii tubulin and vimentin in Adrenal Cortex Carcinoma sw13 cells
FEBS Letters, 2000Co-Authors: Rachel Butler, Janice Robertson, Jean-marc GalloAbstract:During embryogenesis, the maturation of neuroblasts into neurones is accompanied by the down-regulation of vimentin and by the expression of neuronal microtubular proteins. Here, we show that human Adrenal Cortex SW13 cells express βIII-tubulin, MAP2b and tau. Analysis of vimentin-positive and -negative subclones of SW13 cells revealed that, under defined cultured conditions, βIII-tubulin and MAP2b were present only in vimentin-deficient cells and that βIII-tubulin repression occurred at the transcriptional level in vimentin-positive cells. These results suggest that vimentin repression and βIII-tubulin expression are co-ordinated by an upstream mechanism relevant to the control of cytoskeletal protein expression during neuronal development.
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Mutually exclusive expression of βIII‐tubulin and vimentin in Adrenal Cortex Carcinoma SW13 cells
FEBS Letters, 2000Co-Authors: Rachel Butler, Janice Robertson, Jean-marc GalloAbstract:During embryogenesis, the maturation of neuroblasts into neurones is accompanied by the down-regulation of vimentin and by the expression of neuronal microtubular proteins. Here, we show that human Adrenal Cortex SW13 cells express βIII-tubulin, MAP2b and tau. Analysis of vimentin-positive and -negative subclones of SW13 cells revealed that, under defined cultured conditions, βIII-tubulin and MAP2b were present only in vimentin-deficient cells and that βIII-tubulin repression occurred at the transcriptional level in vimentin-positive cells. These results suggest that vimentin repression and βIII-tubulin expression are co-ordinated by an upstream mechanism relevant to the control of cytoskeletal protein expression during neuronal development.