Adrenal Cortex Function

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Jaakko Mononen - One of the best experts on this subject based on the ideXlab platform.

  • sand floor for farmed blue foxes effects on claws Adrenal Cortex Function growth and fur properties
    International Journal of Zoology, 2009
    Co-Authors: Leena Ahola, Tarja Koistinen, Jaakko Mononen
    Abstract:

    Farmed blue foxes (Vulpes lagopus) are traditionally housed on mesh floors where they are unable to perform certain species-specific behaviours, such as digging, which may compromise the animals' welfare. This study describes how a possibility to use in-cage sand floor affects welfare-related variables like growth of the claws, Adrenal Cortex Function, and fur properties in juvenile blue foxes. The foxes (

  • effects of group housing in an enlarged cage system on growth bite wounds and Adrenal Cortex Function in farmed blue foxes alopex lagopus
    Animal Welfare, 2000
    Co-Authors: Leena Ahola, Mikko Harri, Jaakko Mononen, Sari Kasanen, Teija Pyykonen
    Abstract:

    In this study we measured the welfare of farmed blue foxes housed in two different social and spatial conditions: (i) traditional housing (group T) where a male and a female cub were housed together and their vixen alone in standard (1.2 m2) fox cages; and (ii) family housing (group F) where a vixen and her 5 cubs were housed together in a connected 6-cage system (7.2 m2). Production-related welfare parameters (weight gain and the incidence of bite wounds on fur) as well as physiological ones (Adrenal mass and serum cortisol response to ACTH administration) were measured in these two groups. No differences were found in any of the measured parameters between the vixens housed in traditional and family units. In cubs, there was less difference between the sexes in weight gain in group F than in group T, and a significantly lower weight gain was evident only in group T female cubs. The serum cortisol level in response to an ACTH challenge was higher in group T cubs and independent of the sex of the animal, while heavier Adrenals were observed in group T male cubs only. It is concluded that the enlarged cage system combined with group housing had some beneficial effects on the measured performance- and welfare-related indicators in blue fox cubs.

  • Relationship between hyponeophagia and Adrenal Cortex Function in farmed foxes.
    Physiology & behavior, 1999
    Co-Authors: Teppo Rekila, Mikko Harri, Liisa Jalkanen, Jaakko Mononen
    Abstract:

    The Adrenal Cortex Function of farmed blue (Alopex lagopus) and silver foxes (Vulpes vulpes) differing in their reaction in the feeding test were assessed. The urine cortisol:creatinine ratio was lower for those animals eating in the feeding test in comparison to those not eating in both species. In addition, eater silver foxes had lower baseline serum cortisol concentration and also lower serum cortisol concentration 2 h after ACTH administration than noneaters. There were no differences in any serum cortisol levels between the eater and noneater blue foxes. The weights of body and Adrenals did not differ between confident and fearful animals in either species. The present study demonstrates that animals not eating in the feeding test may have higher fearfulness and be more stressed than animals eating.

  • relationship between hyponeophagia and Adrenal Cortex Function in farmed foxes
    Physiology & Behavior, 1998
    Co-Authors: Teppo Rekila, Mikko Harri, Liisa Jalkanen, Jaakko Mononen
    Abstract:

    Abstract REKILA, T., M. HARRI, L. JALKANEN AND J. MONONEN. Relationship between hyponeophagia and Adrenal Cortex Function in farmed foxes. PHYSIOL BEHAV 65 (4/5) 779–783, 1999.—The Adrenal Cortex Function of farmed blue ( Alopex lagopus ) and silver foxes ( Vulpes vulpes ) differing in their reaction in the feeding test were assessed. The urine cortisol:creatinine ratio was lower for those animals eating in the feeding test in comparison to those not eating in both species. In addition, eater silver foxes had lower baseline serum cortisol concentration and also lower serum cortisol concentration 2 h after ACTH administration than noneaters. There were no differences in any serum cortisol levels between the eater and noneater blue foxes. The weights of body and Adrenals did not differ between confident and fearful animals in either species. The present study demonstrates that animals not eating in the feeding test may have higher fearfulness and be more stressed than animals eating.

Li Liangcheng - One of the best experts on this subject based on the ideXlab platform.

  • the effect of the simulated altitude hypoxia on the development of Adrenal Cortex Function of neonatal rats
    Chinese journal of applied physiology, 1997
    Co-Authors: Du Jizeng, Yang Shengmei, Li Liangcheng
    Abstract:

    The response of the corticosterone in neonatal rats to simulated altitude hypoxia and the development of their Adrenal Cortex Function at 5 km altitude was investgated. When exposed to 5 km and 7 km altitude for 24h, the content of Adrenal Cortex and plasmic corticosterone of 7d (7 days old) rats did not change. But the plasmic corticosterone decreased in 14d rats at 7 km altitude (20.33% of control). The plasmic corticosterone of 21d rats also reduced at 7 km (5% of control), and their Adrenal gland corticosterone increased significantly at 5 km and 7 km (144% and 167% of control, respectively). For 28d rats, their plasmic corticosterone stopped to decrease under hypoxia, and the content of Adrenal gland corticosterone increased at 7 km (164% of control), suggesting that in the neonatal rat before 28d old the response of the biosyntheses of Adrenal corticosterone to hypoxia was much sensitive than the release of corticosterone. When 1 day old neonatal rats developed at 5 km altitude for 3 and 7d, the development of the Function of their Adrenal corticosterone was not influenced. But when developed for 14, 21 and 28d, the content of plasmic and Adrenal gland corticosterone decreased significantly, and the development of the Function of Adrenal gland was inhibited severely.

Mikko Harri - One of the best experts on this subject based on the ideXlab platform.

  • effects of group housing in an enlarged cage system on growth bite wounds and Adrenal Cortex Function in farmed blue foxes alopex lagopus
    Animal Welfare, 2000
    Co-Authors: Leena Ahola, Mikko Harri, Jaakko Mononen, Sari Kasanen, Teija Pyykonen
    Abstract:

    In this study we measured the welfare of farmed blue foxes housed in two different social and spatial conditions: (i) traditional housing (group T) where a male and a female cub were housed together and their vixen alone in standard (1.2 m2) fox cages; and (ii) family housing (group F) where a vixen and her 5 cubs were housed together in a connected 6-cage system (7.2 m2). Production-related welfare parameters (weight gain and the incidence of bite wounds on fur) as well as physiological ones (Adrenal mass and serum cortisol response to ACTH administration) were measured in these two groups. No differences were found in any of the measured parameters between the vixens housed in traditional and family units. In cubs, there was less difference between the sexes in weight gain in group F than in group T, and a significantly lower weight gain was evident only in group T female cubs. The serum cortisol level in response to an ACTH challenge was higher in group T cubs and independent of the sex of the animal, while heavier Adrenals were observed in group T male cubs only. It is concluded that the enlarged cage system combined with group housing had some beneficial effects on the measured performance- and welfare-related indicators in blue fox cubs.

  • Relationship between hyponeophagia and Adrenal Cortex Function in farmed foxes.
    Physiology & behavior, 1999
    Co-Authors: Teppo Rekila, Mikko Harri, Liisa Jalkanen, Jaakko Mononen
    Abstract:

    The Adrenal Cortex Function of farmed blue (Alopex lagopus) and silver foxes (Vulpes vulpes) differing in their reaction in the feeding test were assessed. The urine cortisol:creatinine ratio was lower for those animals eating in the feeding test in comparison to those not eating in both species. In addition, eater silver foxes had lower baseline serum cortisol concentration and also lower serum cortisol concentration 2 h after ACTH administration than noneaters. There were no differences in any serum cortisol levels between the eater and noneater blue foxes. The weights of body and Adrenals did not differ between confident and fearful animals in either species. The present study demonstrates that animals not eating in the feeding test may have higher fearfulness and be more stressed than animals eating.

  • relationship between hyponeophagia and Adrenal Cortex Function in farmed foxes
    Physiology & Behavior, 1998
    Co-Authors: Teppo Rekila, Mikko Harri, Liisa Jalkanen, Jaakko Mononen
    Abstract:

    Abstract REKILA, T., M. HARRI, L. JALKANEN AND J. MONONEN. Relationship between hyponeophagia and Adrenal Cortex Function in farmed foxes. PHYSIOL BEHAV 65 (4/5) 779–783, 1999.—The Adrenal Cortex Function of farmed blue ( Alopex lagopus ) and silver foxes ( Vulpes vulpes ) differing in their reaction in the feeding test were assessed. The urine cortisol:creatinine ratio was lower for those animals eating in the feeding test in comparison to those not eating in both species. In addition, eater silver foxes had lower baseline serum cortisol concentration and also lower serum cortisol concentration 2 h after ACTH administration than noneaters. There were no differences in any serum cortisol levels between the eater and noneater blue foxes. The weights of body and Adrenals did not differ between confident and fearful animals in either species. The present study demonstrates that animals not eating in the feeding test may have higher fearfulness and be more stressed than animals eating.

Bogusław Okopień - One of the best experts on this subject based on the ideXlab platform.

  • Drug-induced changes in Adrenal Cortex Function
    Wiadomości lekarskie (Warsaw Poland), 2020
    Co-Authors: Robert Krysiak, Karolina Kowalcze, Bogusław Okopień
    Abstract:

    Glucocorticoids, commonly used in the treatment of various disorders, particularly if administered at high doses, may lead to the development of iatrogenic Cushing's syndrome, being by far the most common iatrogenic disorder of the Adrenal gland. In some cases, however, Adrenal Cortex Function may be affected by other drugs and risk of the development of various clinical entities is dependent on the drug, its dose, as well as on the duration of the treatment. This risk is also related to the baseline Function of this gland. Because little is known about the influence of non-hormonal drugs on Adrenal Cortex Function, many physicians are unaware of the existence of these disorders, which, if not detected in the early stages, can pose serious health risk. Although distinguishing endogenous from exogenous Adrenal Cortex disorders is usually straightforward and based on the patient's history, in rare cases the investigation and differentiation of iatrogenic Adrenal Cortex disorders may be diagnostically challenging. This article raises awareness of the association between drugs other than Adrenal Cortex hormones and the Function of this gland, and provide the reader with recommendations concerning the diagnosis and treatment of iatrogenic Adrenal Cortex disorders.

  • The effect of ezetimibe-statin combination on steroid hormone production in men with coronary artery disease and low cholesterol levels
    Pharmacological Reports, 2015
    Co-Authors: Robert Krysiak, Beata Kowalska, Witold Żmuda, Bogusław Okopień
    Abstract:

    Background Aggressive statin treatment was found to slightly reduce testosterone production. The aim of this study was to compare the effects of ezetimibe-statin combination and high-dose statin therapy on testicular and Adrenal Cortex Function in men with LDL cholesterol levels below 70 mg/dL. Methods The study included 26 adult men with coronary artery disease. Twelve of these patients did not tolerate high-dose statin therapy and were treated with lower doses of a statin plus ezetimibe. Fourteen patients tolerating high-dose simvastatin or rosuvastatin treatment continued high-dose statin therapy throughout the study period. Plasma lipids, glucose homeostasis markers and plasma levels of testosterone, cortisol, dehydroepiandrosterone sulphate, sex hormone-binding globulin, gonadotropins and ACTH, as well as urine free cortisol were assessed at baseline and after 16 weeks of treatment. Results Replacing high-dose statin therapy with ezetimibe/statin combination therapy reduced plasma levels of LH by 32% ( p = 0.043), as well as increased plasma levels of testosterone by 20% ( p = 0.038). Ezetimibe/statin combination did not induce any significant changes in plasma levels or urine excretion of the remaining hormones. At the end of the study, plasma LH levels were higher, while plasma testosterone levels were lower in patients receiving the combination therapy than in those treated only with high-dose statin. Conclusions Our results indicate that ezetimibe combined with moderate statin dose exerts a less pronounced effect on testicular Function in comparison with high-dose statin therapy.

Teppo Rekila - One of the best experts on this subject based on the ideXlab platform.

  • Relationship between hyponeophagia and Adrenal Cortex Function in farmed foxes.
    Physiology & behavior, 1999
    Co-Authors: Teppo Rekila, Mikko Harri, Liisa Jalkanen, Jaakko Mononen
    Abstract:

    The Adrenal Cortex Function of farmed blue (Alopex lagopus) and silver foxes (Vulpes vulpes) differing in their reaction in the feeding test were assessed. The urine cortisol:creatinine ratio was lower for those animals eating in the feeding test in comparison to those not eating in both species. In addition, eater silver foxes had lower baseline serum cortisol concentration and also lower serum cortisol concentration 2 h after ACTH administration than noneaters. There were no differences in any serum cortisol levels between the eater and noneater blue foxes. The weights of body and Adrenals did not differ between confident and fearful animals in either species. The present study demonstrates that animals not eating in the feeding test may have higher fearfulness and be more stressed than animals eating.

  • relationship between hyponeophagia and Adrenal Cortex Function in farmed foxes
    Physiology & Behavior, 1998
    Co-Authors: Teppo Rekila, Mikko Harri, Liisa Jalkanen, Jaakko Mononen
    Abstract:

    Abstract REKILA, T., M. HARRI, L. JALKANEN AND J. MONONEN. Relationship between hyponeophagia and Adrenal Cortex Function in farmed foxes. PHYSIOL BEHAV 65 (4/5) 779–783, 1999.—The Adrenal Cortex Function of farmed blue ( Alopex lagopus ) and silver foxes ( Vulpes vulpes ) differing in their reaction in the feeding test were assessed. The urine cortisol:creatinine ratio was lower for those animals eating in the feeding test in comparison to those not eating in both species. In addition, eater silver foxes had lower baseline serum cortisol concentration and also lower serum cortisol concentration 2 h after ACTH administration than noneaters. There were no differences in any serum cortisol levels between the eater and noneater blue foxes. The weights of body and Adrenals did not differ between confident and fearful animals in either species. The present study demonstrates that animals not eating in the feeding test may have higher fearfulness and be more stressed than animals eating.