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Aflatoxicosis

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Mosaad A Abdelwahhab – One of the best experts on this subject based on the ideXlab platform.

  • antioxidant property of nigella sativa black cumin and syzygium aromaticum clove in rats during Aflatoxicosis
    Journal of Applied Toxicology, 2005
    Co-Authors: Mosaad A Abdelwahhab
    Abstract:

    Aflatoxins, a group of closely related, extremely toxic mycotoxins produced by Aspergillus flavus and A. parasiticus, can occur as natural contaminants of foods and feeds. Aflatoxins have been shown to be hepatotoxic, carcinogenic, mutagenic and teratogenic to different animal species. Nigella sativa (black cumin) and Syzygium aromaticum (clove) oil are used for the treatment of inflammatory diseases and have antioxidant properties. The aim of this study was to investigate the ability of these volatile oils to scavenge free radicals generated during Aflatoxicosis. Sixty male rats were divided into six treatment groups, including a control group, and the groups were treated for 30 days with Nigella sativa and Syzygium aromaticum oils with or without aflatoxin. Blood samples were collected at the end of the experimental period for haematological and biochemical analysis. The results indicated that exposure to aflatoxins resulted in haematological and biochemical changes typical for Aflatoxicosis. Treatment with Nigella sativa and Syzygium aromaticum oil of rats fed an aflatoxin-contaminated diet resulted in significant protection against Aflatoxicosis. Moreover, Nigella sativa oil was found to be more effective than Syzygium aromaticum oil in restoring the parameters that were altered by aflatoxin in rats. Copyright © 2005 John Wiley & Sons, Ltd.

  • antioxidant property of nigella sativa black cumin and syzygium aromaticum clove in rats during Aflatoxicosis
    Journal of Applied Toxicology, 2005
    Co-Authors: Mosaad A Abdelwahhab, Soher E Aly
    Abstract:

    Aflatoxins, a group of closely related, extremely toxic mycotoxins produced by Aspergillus flavus and A. parasiticus, can occur as natural contaminants of foods and feeds. Aflatoxins have been shown to be hepatotoxic, carcinogenic, mutagenic and teratogenic to different animal species. Nigella sativa (black cumin) and Syzygium aromaticum (clove) oil are used for the treatment of inflammatory diseases and have antioxidant properties. The aim of this study was to investigate the ability of these volatile oils to scavenge free radicals generated during Aflatoxicosis. Sixty male rats were divided into six treatment groups, including a control group, and the groups were treated for 30 days with Nigella sativa and Syzygium aromaticum oils with or without aflatoxin. Blood samples were collected at the end of the experimental period for haematological and biochemical analysis. The results indicated that exposure to aflatoxins resulted in haematological and biochemical changes typical for Aflatoxicosis. Treatment with Nigella sativa and Syzygium aromaticum oil of rats fed an aflatoxin-contaminated diet resulted in significant protection against Aflatoxicosis. Moreover, Nigella sativa oil was found to be more effective than Syzygium aromaticum oil in restoring the parameters that were altered by aflatoxin in rats.

Soher E Aly – One of the best experts on this subject based on the ideXlab platform.

  • antioxidant property of nigella sativa black cumin and syzygium aromaticum clove in rats during Aflatoxicosis
    Journal of Applied Toxicology, 2005
    Co-Authors: Mosaad A Abdelwahhab, Soher E Aly
    Abstract:

    Aflatoxins, a group of closely related, extremely toxic mycotoxins produced by Aspergillus flavus and A. parasiticus, can occur as natural contaminants of foods and feeds. Aflatoxins have been shown to be hepatotoxic, carcinogenic, mutagenic and teratogenic to different animal species. Nigella sativa (black cumin) and Syzygium aromaticum (clove) oil are used for the treatment of inflammatory diseases and have antioxidant properties. The aim of this study was to investigate the ability of these volatile oils to scavenge free radicals generated during Aflatoxicosis. Sixty male rats were divided into six treatment groups, including a control group, and the groups were treated for 30 days with Nigella sativa and Syzygium aromaticum oils with or without aflatoxin. Blood samples were collected at the end of the experimental period for haematological and biochemical analysis. The results indicated that exposure to aflatoxins resulted in haematological and biochemical changes typical for Aflatoxicosis. Treatment with Nigella sativa and Syzygium aromaticum oil of rats fed an aflatoxin-contaminated diet resulted in significant protection against Aflatoxicosis. Moreover, Nigella sativa oil was found to be more effective than Syzygium aromaticum oil in restoring the parameters that were altered by aflatoxin in rats.

T.s. Johri – One of the best experts on this subject based on the ideXlab platform.

Jammi Raghavendra Rao – One of the best experts on this subject based on the ideXlab platform.

  • Influence of dietary aflatoxin on Eimeria uzura infection in Japanese quail (Coturnix coturnix japonica).
    Veterinary parasitology, 1995
    Co-Authors: Jammi Raghavendra Rao, N.n. Sharma, T.s. Johri
    Abstract:

    Abstract A study was conducted to assess the influence of dietary aflatoxin on Eimeria uzura in Japanese quail (Coturnix coturnix japonica). Quail receiving 1 part per million (ppm) of dietary aflatoxin B1 and inoculated with 105 sporulated oocysts of E. uzura gained significantly less weight than chicks receiving either aflatoxin or coccidia alone. Increased morbidity, mortality and decreased efficiency of feed utilization were also evident. The combination of E. uzura infection and Aflatoxicosis resulted in reduction in packed cell volume (PCV) and haemoglobin (Hb). The combination of E. uzura infection and Aflatoxicosis in Japanese quail may influence the course of coccidial infection due to the additive effects of aflatoxin.

N.n. Sharma – One of the best experts on this subject based on the ideXlab platform.

  • Influence of dietary aflatoxin on Eimeria uzura infection in Japanese quail (Coturnix coturnix japonica).
    Veterinary parasitology, 1995
    Co-Authors: Jammi Raghavendra Rao, N.n. Sharma, T.s. Johri
    Abstract:

    Abstract A study was conducted to assess the influence of dietary aflatoxin on Eimeria uzura in Japanese quail (Coturnix coturnix japonica). Quail receiving 1 part per million (ppm) of dietary aflatoxin B1 and inoculated with 105 sporulated oocysts of E. uzura gained significantly less weight than chicks receiving either aflatoxin or coccidia alone. Increased morbidity, mortality and decreased efficiency of feed utilization were also evident. The combination of E. uzura infection and Aflatoxicosis resulted in reduction in packed cell volume (PCV) and haemoglobin (Hb). The combination of E. uzura infection and Aflatoxicosis in Japanese quail may influence the course of coccidial infection due to the additive effects of aflatoxin.