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Agglutination

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Edward J Young – One of the best experts on this subject based on the ideXlab platform.

  • serologic diagnosis of human brucellosis analysis of 214 cases by Agglutination tests and review of the literature
    Clinical Infectious Diseases, 1991
    Co-Authors: Edward J Young

    Abstract:

    Abstract The serum Agglutination test (SAT) and 2-mercaptoethanol (2ME) Agglutination were used in studies of the sera of 214 patients in whom brucellosis was suspected. On the basis of historical, epidemiologic, clinical, and serologic data, four groups were identified: group I (108 cases) had negative Agglutination reactions, and brucellosis was considered unlikely; group II (57 cases) had positive Agglutination reactions, and active brucellosis was diagnosed; group III (37 cases) had positive Agglutination reactions, but other factors–notably, a history of prior infection–made inactive brucellosis likely; and group IV (12 cases) had positive Agglutination reactions, but insufficient data were available for further classification. Most patients with active brucellosis had agglutinin titers of greater than or equal to 160; however, no single titer was always diagnostic. Although more sensitive tests are available, Agglutination reactions provide data sufficient to differentiate active from inactive disease when other factors are considered and follow-up sera are tested. This article discusses individual cases and reviews the literature on the diagnosis of brucellosis.

Minalben Bharat Kumar Trivedi – One of the best experts on this subject based on the ideXlab platform.

  • Study of diagnostic efficacy of widal slide Agglutination test against widal tube Agglutination test in enteric fever
    Indian Journal of Microbiology Research, 2017
    Co-Authors: Roshni Pranav Patel, Minalben Bharat Kumar Trivedi

    Abstract:

    Introduction: Enteric fever is a major and persistent public health problem in India. The slide widal is most commonly performed rapid method to diagnose due to its convenience, but its results are required to be compare with more standardly established tube widal test for its actual diagnostic significance. This study aims to compare the result of slide widal test with tube widal test to ascertain any significant difference between two methods.
    Materials and Method: The 100 pre-collected serum samples with widal test request were received for the study over the six months period. Comparison of slide widal Agglutination test with tube widal Agglutination was done considering tube widal as a standard.
    Result: The slide widal Agglutination test shows false positive result in 5.3% and 48.1% serum samples with S.typhi O antigen & S.typhi H antigen, respectively. The Positive Predictive Value of widal slide Agglutination test for O antigen and H antigen is 94% and 52% respectively.
    Conclusion: The slide widal Agglutination test showed high false positive rate and low positive predictive value especially with S.typhi H antigen. Therefore, the result of slide widal Agglutination needs to be confirmed by tube widal Agglutination test.

    Keywords: Agglutination tests, Comparison, Slide, Tube, Widal test

  • Study of diagnostic efficacy of widal slide Agglutination test against widal tube Agglutination test in enteric fever
    Indian Journal of Microbiology Research, 2017
    Co-Authors: Roshni Pranav Patel, Minalben Bharat Kumar Trivedi

    Abstract:

    Introduction: Enteric fever is a major and persistent public health problem in India. The slide widal is most commonly performed rapid method to diagnose due to its convenience, but its results are required to be compare with more standardly established tube widal test for its actual diagnostic significance. This study aims to compare the result of slide widal test with tube widal test to ascertain any significant difference between two methods.
    Materials and Method: The 100 pre-collected serum samples with widal test request were received for the study over the six months period. Comparison of slide widal Agglutination test with tube widal Agglutination was done considering tube widal as a standard.
    Result: The slide widal Agglutination test shows false positive result in 5.3% and 48.1% serum samples with S.typhi O antigen & S.typhi H antigen, respectively. The Positive Predictive Value of widal slide Agglutination test for O antigen and H antigen is 94% and 52% respectively.
    Conclusion: The slide widal Agglutination test showed high false positive rate and low positive predictive value especially with S.typhi H antigen. Therefore, the result of slide widal Agglutination needs to be confirmed by tube widal Agglutination test.

    Keywords: Agglutination tests, Comparison, Slide, Tube, Widal test

Catherine M Lynch – One of the best experts on this subject based on the ideXlab platform.

  • external use of an oxidized regenerated cellulose agent in the treatment of labial Agglutination in postmenopausal women
    Obstetrics & Gynecology, 2018
    Co-Authors: A M Wyman, Elizabeth Lafranchise, Catherine M Lynch

    Abstract:

    Background Vulvovaginal diseases affect women of all ages. Vaginal atrophy and vulvar lichen sclerosus are common etiologies for chronic vulvovaginal pruritus and labial Agglutination in both prepubertal and postmenopausal women. Cases We present two cases of a novel approach in management of symptomatic labial Agglutination in postmenopausal women. At the time of surgical intervention, an oxidized regenerated cellulose gauze was sutured in place within the operative field of separation of the labia minora and clitoral hood adhesions. At more than 18-months’ follow-up, no recurrence of Agglutination has been noted. Conclusion The use of an oxidized regenerated cellulose agent may create an effective barrier to recurrence of labial Agglutination in postmenopausal women.