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William H. Wilson – One of the best experts on this subject based on the ideXlab platform.

  • source monitoring deficits for self generated stimuli in schizophrenia multinomial modeling of data from three sources
    Schizophrenia Research, 2002
    Co-Authors: Richard S E Keefe, Miriam C Arnold, Ute J. Bayen, Joseph Patrick Mcevoy, William H. Wilson


    Abstract Introduction : Schizophrenia patients, particularly those with specific types of hallucinations and delusions, may have a deficit in monitoring the generation of thought. This deficit, termed autonoetic Agnosia , may result in the conclusion that self-generated thoughts come from an external source. Methods : This study assessed autonoetic Agnosia in 29 schizophrenic patients and 19 controls by applying a recently developed technique from cognitive science: multinomial modeling of source-monitoring data. Results : Schizophrenic patients demonstrated deficits in monitoring the source of self-generated information, yet performed similarly to controls in monitoring the source of visual and auditory information. Schizophrenic patients with specific “target” symptoms such as auditory hallucinations and thought insertion had greater deficits than other patients in recognizing self-generated information. Conclusion : This study offers partial support for the notion that schizophrenic patients manifest autonoetic Agnosia.

Lynn J Speedie – One of the best experts on this subject based on the ideXlab platform.

  • characteristics of auditory Agnosia in a child with severe traumatic brain injury a case report
    Brain and Language, 2005
    Co-Authors: Nina Hattiangadi, Joseph P Pillion, Beth S Slomine, James R Christensen, Melissa Katrina Trovato, Lynn J Speedie


    We present a case that is unusual in many respects from other documented incidences of auditory Agnosia, including the mechanism of injury, age of the individual, and location of neurological insult. The clinical presentation is one of disturbance in the perception of spoken language, music, pitch, emotional prosody, and temporal auditory processing in the absence of significant deficits in the comprehension of written language, expressive language production, or peripheral auditory function. Furthermore, the patient demonstrates relatively preserved function in other aspects of audition such as sound localization, voice recognition, and perception of animal noises and environmental sounds. This case study demonstrates that auditory Agnosia is possible following traumatic brain injury in a child, and illustrates the necessity of assessment with a wide variety of auditory stimuli to fully characterize auditory Agnosia in a single individual.

Mohamed Saoud – One of the best experts on this subject based on the ideXlab platform.

  • low frequency repetitive transcranial magnetic stimulation improves source monitoring deficit in hallucinating patients with schizophrenia
    Schizophrenia Research, 2006
    Co-Authors: Jérome Brunelin, Emmanuel Poulet, Benoit Bediou, Lassad Kallel, Jean Dalery, Thierry Damato, Mohamed Saoud


    Auditory hallucinations have been associated with a disruption in monitoring one’s own speech suggesting an autonoetic Agnosia in schizophrenia. This deficit can be measured by a source monitoring task. Low frequency transcranial magnetic stimulations (rTMS) applied to the left temporoparietal cortex can inhibit cortical areas involved both in autonoetic Agnosia (which means ‘the inability to identify self-generated mental events’) and in auditory hallucinations (AH) phenomena. Although improvements in AH have been repeatedly reported following rTMS treatment, effects on autonoetic Agnosia measured by source monitoring have never been investigated. We aimed to investigate the relation between improvements in AH and source monitoring performance after rTMS treatment. Twenty four right-handed refractory schizophrenic patients with hallucinations randomly received sham or active 10.0001-Hz rTMS to the left temporoparietal cortex and performed 2 source monitoring tasks requiring discrimination between silent- and overt-reading words before and after rTMS sessions. Compared to sham, active rTMS significantly improved AH. Source monitoring performances and the improvements tended to correlate, which would support a specific relation between autonoetic Agnosia and auditory hallucinations.