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Wojciech Szaniawski - One of the best experts on this subject based on the ideXlab platform.

  • cutaneous protothecosis and aids
    Journal of The American Academy of Dermatology, 1994
    Co-Authors: Andrew Woolrich, Evelyn K Koestenblatt, Wojciech Szaniawski
    Abstract:

    Cutaneous protothecosis is an uncommon Algal Infection with a varied clinical presentation that occurs mainly in immunocompromised patients. We describe a 33-year-old Hispanic woman with AIDS who had a verrucous plaque on the dorsum of her hand. A biopsy specimen revealed organisms suggestive of Prototheca . Culture confirmed the organism to be Prototheca wickerhamii . To our knowledge, this is the first case of cutaneous protothecosis reported in a patient with AIDS.

Andrew Woolrich - One of the best experts on this subject based on the ideXlab platform.

  • cutaneous protothecosis and aids
    Journal of The American Academy of Dermatology, 1994
    Co-Authors: Andrew Woolrich, Evelyn K Koestenblatt, Wojciech Szaniawski
    Abstract:

    Cutaneous protothecosis is an uncommon Algal Infection with a varied clinical presentation that occurs mainly in immunocompromised patients. We describe a 33-year-old Hispanic woman with AIDS who had a verrucous plaque on the dorsum of her hand. A biopsy specimen revealed organisms suggestive of Prototheca . Culture confirmed the organism to be Prototheca wickerhamii . To our knowledge, this is the first case of cutaneous protothecosis reported in a patient with AIDS.

Anthony P Cannella - One of the best experts on this subject based on the ideXlab platform.

  • case report olecranon bursitis due to prototheca wickerhamii in an immunocompromised patient
    American Journal of Tropical Medicine and Hygiene, 2019
    Co-Authors: Kruti Yagnik, Raphael C Bosse, Jennifer Reppucci, Rachel Butts, Shehla Islam, Anthony P Cannella
    Abstract:

    : Human protothecosis is a rare Algal Infection caused by Prototheca; it is a ubiquitous achlorophyllic alga, which rarely causes human disease. Currently, the pathogenesis remains unclear and no treatment options have been elucidated. We present a case of olecranon bursitis caused by Prototheca wickerhamii in an immunocompromised patient. A 45-year-old man presented with left elbow pain after scraping his elbow on a tree. He reported significant pain and swelling of the elbow after injury, which resolved without intervention. He was diagnosed with HIV/AIDS Infection and started on antiretroviral therapy. Afterward, he experienced recurrent elbow swelling and pain; an incision and drainage was performed and cultures demonstrated P. wickerhamii. Unsuccessful treatment with oral voriconazole led to an attempt at therapy with parental amphotericin and oral doxycycline; however the patient left against medical advice. He presented to our facility and both parental amphotericin and doxycycline were initiated with planned outpatient bursectomy. He clinically improved on that regimen but left against medical advice before completing his recommended course of IV amphotericin and oral doxycycline. Patients diagnosed with disseminated protothecosis can have a mortality rate upward of 67%. Given the rarity of this pathogen, no official treatment guidelines exist and there are few studies analyzing the antimicrobial susceptibility of Prototheca. Management is challenging because of slow-growing nature of the algae, paucity of research studies, and limited susceptibility of this pathogen. This case adds to the limited body of literature by demonstrating the clinical presentation of protothecosis and highlighting the pathology and current treatment options.

Marta Catarina Fernandes - One of the best experts on this subject based on the ideXlab platform.

  • phenotypic and genotypic characterization of prototheca zopfii in a dog with enteric signs
    Research in Veterinary Science, 2009
    Co-Authors: Marcio Garcia Ribeiro, Uwe Roesler, Marconi Rodrigues De Farias, Katja Roth, Sabrina Mari Rodigheri, Marco Antonio Ostrowsky, Tatiana Salerno, Amanda Keller Siqueira, Marta Catarina Fernandes
    Abstract:

    This is a case report of enteric protothecosis caused by Prototheca zopfii in an eight-year-old male mixed breed dog with a history of chronic bloody diarrhea, loss of appetite and weight loss. Algae were isolated from rectal scrapings in defibrinated sheep blood agar and dextrose Sabouraud agar. Cytological evaluation showed the presence of globular and cylindrical organisms with a defined capsule and variable number of endospores, characteristic of the genus Prototheca, in the rectum of the animal. Scanning electron microscopy of P. zopfii strains at different development stages confirmed the diagnosis of Algal Infection. Molecular identification using a conserved 18S rDNA gene sequence determined that the strain belonged to genotype 2. This report describes success on treatment of canine protothecosis, diagnosed based on clinical, cytological, microbiological, scanning electron microscopy and genotypical findings.

Evelyn K Koestenblatt - One of the best experts on this subject based on the ideXlab platform.

  • cutaneous protothecosis and aids
    Journal of The American Academy of Dermatology, 1994
    Co-Authors: Andrew Woolrich, Evelyn K Koestenblatt, Wojciech Szaniawski
    Abstract:

    Cutaneous protothecosis is an uncommon Algal Infection with a varied clinical presentation that occurs mainly in immunocompromised patients. We describe a 33-year-old Hispanic woman with AIDS who had a verrucous plaque on the dorsum of her hand. A biopsy specimen revealed organisms suggestive of Prototheca . Culture confirmed the organism to be Prototheca wickerhamii . To our knowledge, this is the first case of cutaneous protothecosis reported in a patient with AIDS.