The Experts below are selected from a list of 207 Experts worldwide ranked by ideXlab platform
Luminita Vladescu - One of the best experts on this subject based on the ideXlab platform.
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Determination of para-Aminobenzoic Acid, a degradation product of procaine hydrochloride, by zero-crossing first-derivative spectrometry
Analytical and Bioanalytical Chemistry, 2002Co-Authors: Irinel Badea, Dana Moja, Luminita VladescuAbstract:A first derivative spectrometric method has been developed for the determination of the para -Aminobenzoic Acid (PABA), a related substance and degradation product of the local anesthetic procaine hydrochloride (PH). The wavelength selected for the determination of para -Aminobenzoic Acid in the presence of procaine was 290 nm. At this wavelength the calibration graphs relating the amplitude of the signals to the concentration of para -Aminobenzoic Acid were linear up to 10 mg L^–1. The detection limit of para -Aminobenzoic Acid was 0.70 mg L^–1. The method is simple and rapid and does not require preliminary treatment of the sample. The method was validated.
Ake C Rasmuson - One of the best experts on this subject based on the ideXlab platform.
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thermodynamics and nucleation kinetics of m Aminobenzoic Acid polymorphs
Crystal Growth & Design, 2010Co-Authors: Michael Svard, Fredrik L Nordstrom, Tanja Jasnobulka, Ake C RasmusonAbstract:The polymorphism of m-Aminobenzoic Acid has been investigated. Two polymorphs have been identified and characterized by X-ray powder diffraction (XRPD), Fourier transform IR (FTIR), microscopy, and ...
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polymorphism and crystallization of p Aminobenzoic Acid
Crystal Growth & Design, 2004Co-Authors: Sandra Gracin, Ake C RasmusonAbstract:p-Aminobenzoic Acid (PABA) crystallizes in two different polymorphic forms: the alpha-polymorph, which is the commercially available form and appears as long, fibrous needles, and the beta-polymorp ...
Irinel Badea - One of the best experts on this subject based on the ideXlab platform.
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Determination of para-Aminobenzoic Acid, a degradation product of procaine hydrochloride, by zero-crossing first-derivative spectrometry
Analytical and Bioanalytical Chemistry, 2002Co-Authors: Irinel Badea, Dana Moja, Luminita VladescuAbstract:A first derivative spectrometric method has been developed for the determination of the para -Aminobenzoic Acid (PABA), a related substance and degradation product of the local anesthetic procaine hydrochloride (PH). The wavelength selected for the determination of para -Aminobenzoic Acid in the presence of procaine was 290 nm. At this wavelength the calibration graphs relating the amplitude of the signals to the concentration of para -Aminobenzoic Acid were linear up to 10 mg L^–1. The detection limit of para -Aminobenzoic Acid was 0.70 mg L^–1. The method is simple and rapid and does not require preliminary treatment of the sample. The method was validated.
Aurora J Cruzcabeza - One of the best experts on this subject based on the ideXlab platform.
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polymorphism in p Aminobenzoic Acid
CrystEngComm, 2019Co-Authors: Aurora J Cruzcabeza, Roger J Davey, Iain D H Oswald, Martin R Ward, Isaac J SugdenAbstract:We review the polymorphism of p-Aminobenzoic Acid (pABA), a model drug compound whose crystallisation and polymorphic behaviour has been extensively studied in recent years. Beyond the well-known and characterised α and β forms, pABA also crystallises as a γ polymorph, which is structurally similar to the α form. In addition we also compare the newly reported δ form, obtained by high pressure crystallisation and through compression of the α-form. A structural analysis and comparison of all of the forms is presented, the conditions by which each of them is obtained summarised. Crystal structure prediction calculations have also been carried out in order to probe the solid form energy landscape of this compound. The overall picture of the polymorphism of pABA, reveals, surprisingly, the rarity of the β form.
Dana Moja - One of the best experts on this subject based on the ideXlab platform.
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Determination of para-Aminobenzoic Acid, a degradation product of procaine hydrochloride, by zero-crossing first-derivative spectrometry
Analytical and Bioanalytical Chemistry, 2002Co-Authors: Irinel Badea, Dana Moja, Luminita VladescuAbstract:A first derivative spectrometric method has been developed for the determination of the para -Aminobenzoic Acid (PABA), a related substance and degradation product of the local anesthetic procaine hydrochloride (PH). The wavelength selected for the determination of para -Aminobenzoic Acid in the presence of procaine was 290 nm. At this wavelength the calibration graphs relating the amplitude of the signals to the concentration of para -Aminobenzoic Acid were linear up to 10 mg L^–1. The detection limit of para -Aminobenzoic Acid was 0.70 mg L^–1. The method is simple and rapid and does not require preliminary treatment of the sample. The method was validated.
