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Aminocarbonylation

The Experts below are selected from a list of 1305 Experts worldwide ranked by ideXlab platform

Xiaofeng Wu – 1st expert on this subject based on the ideXlab platform

  • Palladium-Catalyzed Amide Synthesis via Aminocarbonylation of Arylboronic Acids with Nitroarenes
    Organic Letters, 2019
    Co-Authors: Jin-bao Peng, Da Li, Hui-qing Geng, Xiaofeng Wu

    Abstract:

    A palladium-catalyzed Aminocarbonylation of aryl boronic acids with nitroarenes for the synthesis of amides has been developed. A wide range of substrates were well-tolerated and gave the corresponding amides in moderate to good yields. No external oxidant or reductant was needed in this procedure. This procedure provides a redox-economical process for the synthesis of amides.

  • a highly efficient palladium catalyzed Aminocarbonylation snar approach to dibenzoxazepinones
    ChemInform, 2015
    Co-Authors: Chaoren Shen, Helfried Neumann, Xiaofeng Wu

    Abstract:

    Various 2-aminophenols and 2-bromofluorobenzenes are used as substrates for the convenient one-pot synthesis of a wide range of dibenzoxazepinones by a palladium-catalyzed Aminocarbonylation/aromatic nucleophilic substitution sequence.

  • A Highly-Efficient Palladium-Catalyzed Aminocarbonylation/SNAr Approach to Dibenzoxazepinones.
    ChemInform, 2015
    Co-Authors: Chaoren Shen, Helfried Neumann, Xiaofeng Wu

    Abstract:

    Various 2-aminophenols and 2-bromofluorobenzenes are used as substrates for the convenient one-pot synthesis of a wide range of dibenzoxazepinones by a palladium-catalyzed Aminocarbonylation/aromatic nucleophilic substitution sequence.

Giancarlo Cravotto – 2nd expert on this subject based on the ideXlab platform

  • highly efficient microwave assisted co Aminocarbonylation with a recyclable pd ii tpp β cyclodextrin cross linked catalyst
    ChemInform, 2015
    Co-Authors: Emanuela Calcio Gaudino, Diego Carnaroglio, Katia Martina, Giovanni Palmisano, Andrea Penoni, Giancarlo Cravotto

    Abstract:

    A new recyclable catalytic system based on Pd(II) embedded in cross-linked cyclodextrin is found to be very efficient in Aminocarbonylation reactions of aryl iodides (I).

  • highly efficient microwave assisted co Aminocarbonylation with a recyclable pd ii tpp β cyclodextrin cross linked catalyst
    Organic Process Research & Development, 2015
    Co-Authors: Emanuela Calcio Gaudino, Diego Carnaroglio, Katia Martina, Giovanni Palmisano, Andrea Penoni, Giancarlo Cravotto

    Abstract:

    The incorporation of the carbonyl moiety into organic molecules using a three-component matrix, including carbon monoxide, an organic halide, and a nucleophilic component, offers a simple and versatile approach to the formation of carboxylic acids, anhydrides, esters, amides, and ketones. The design of a sustainable synthetic protocol for Aminocarbonylation can be efficiently accomplished using a multifaceted strategy that combines solid green catalysts and suitable enabling techniques. The safe and synergistic use of carbon monoxide in a microwave reactor under pressure may be able to create a technological breakthrough in Aminocarbonylation reactions. Moreover, a new recyclable catalytic system “CβCAT” based on Pd(II)-triphenylphosphine embedded in cross-linked β-cyclodextrin (hexamethylene diisocyanate) has been found to be very efficient in aryl iodide Aminocarbonylation reactions.

László Kollár – 3rd expert on this subject based on the ideXlab platform

  • High-yielding synthesis of N-triazolyl carboxamides via palladium-catalysed Aminocarbonylation
    Tetrahedron, 2017
    Co-Authors: Máté Gergely, Borbála Boros, László Kollár

    Abstract:

    Abstract Aminocarbonylation of alkenyl and aryl iodides in the presence of 4-amino-4H-1,2,4-triazole as N-nucleophile was carried out in the presence of palladium catalysts. Both types of substrates have shown high chemoselectivity toward carboxamides, i.e. practically no double carbon monoxide insertion resulting in 2-ketocarboxamides took place. The results have been rationalised on the basis of mechanistic aspects of Aminocarbonylation.

  • Palladium-catalysed Aminocarbonylation of diiodopyridines
    Tetrahedron, 2017
    Co-Authors: Attila Takács, Georgina Márta Varga, Johanna Kardos, László Kollár

    Abstract:

    Abstract The Aminocarbonylation of 2,5- and 2,3-diiodopyridine, as well as 2-chloro-3,4-diiodopyridine with carbon monoxide and various primary and secondary amines was carried out using palladium-catalysed Aminocarbonylation. The formation of the products containing carboxamide and ketocarboxamide functionalities was accompanied by the formation of imides when ortho-diiodo compounds were used as substrates. In spite of several possible reaction pathways, most of the products were synthesised as major product in yields of synthetic interest by the appropriate modification of the reaction conditions.

  • Synthesis of bornene-2,2′-diamino-1,1′-binaphthalene conjugates in palladium-catalysed Aminocarbonylations
    Tetrahedron-asymmetry, 2016
    Co-Authors: Gábor Mikle, Borbála Boros, László Kollár

    Abstract:

    Abstract Palladium-catalysed Aminocarbonylation of a terpenoic iodoalkene (2-iodo-bornene) model compound with both enantiomerically pure and racemic 2,2′-diamino-1,1′-binaphthalene (BINAM) as the N -nucleophile was carried out. All of the diastereoisomers of the monocarboxamide ( N -bornenyl carboxamide) and dicarboxamide ( N , N ′-dinorbornenylcarboxamide) derivatives were synthesised. The diastereoselectivities of the Aminocarbonylation were investigated in both cases: either racemic BINAM was used as the N -nucleophile in the Aminocarbonylation of enantiomerically pure 2-iodobornene or racemic iodobornene was aminocarbonylated with enantiomerically pure BINAM with moderate diastereoselectivities. In this way, all possible diastereoisomers of binaphthalene–bornene conjugates were synthesised in moderate to high yields by asymmetric (diastereoselective) Aminocarbonylation.