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Claudia Moraes De Rezende - One of the best experts on this subject based on the ideXlab platform.
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application of high temperature gas chromatography mass spectrometry to the investigation of glycosidically bound components related to cashew apple Anacardium occidentale l var nanum volatiles
Journal of Agricultural and Food Chemistry, 2000Co-Authors: B Bicalho, F Aquino R Neto, And A C Pinto, Alberto Dos Santos Pereira, Claudia Moraes De RezendeAbstract:Free and bound volatile components of a Brazilian cashew apple variety (Anacardium occidentale L. var. nanum) were obtained by simultaneous distillation−extraction (SDE) and XAD-2 adsorption. According to gas chromatography−mass spectrometry (GC-MS) analyses and retention indices, 62 free volatile constituents were characterized and quantified. They were esters (40%), terpenes (20%), hydrocarbons (14%), fatty acids (9%), aldehydes (8%), alcohols (3%), lactones (3%), ketones (1%), phenols (1%), and norisoprenoids (1%). The glycosidically bound volatile precursors were analyzed by high-temperature GC-MS, after room temperature silylation. Several conjugated alcohols and cinnamic acids were detected and reported as cashew apple glycosyl constituents for the first time. Keywords: Cashew apple; Anacardium occidentale L.; volatile compounds; glycoside; high-temperature gas chromatography
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application of high temperature gas chromatography mass spectrometry to the investigation of glycosidically bound components related to cashew apple Anacardium occidentale l var nanum volatiles
Journal of Agricultural and Food Chemistry, 2000Co-Authors: B Bicalho, F Aquino R Neto, And A C Pinto, Alberto Dos Santos Pereira, Claudia Moraes De RezendeAbstract:Free and bound volatile components of a Brazilian cashew apple variety (Anacardium occidentale L. var. nanum) were obtained by simultaneous distillation-extraction (SDE) and XAD-2 adsorption. According to gas chromatography-mass spectrometry (GC-MS) analyses and retention indices, 62 free volatile constituents were characterized and quantified. They were esters (40%), terpenes (20%), hydrocarbons (14%), fatty acids (9%), aldehydes (8%), alcohols (3%), lactones (3%), ketones (1%), phenols (1%), and norisoprenoids (1%). The glycosidically bound volatile precursors were analyzed by high-temperature GC-MS, after room temperature silylation. Several conjugated alcohols and cinnamic acids were detected and reported as cashew apple glycosyl constituents for the first time.
P J Vithayathil - One of the best experts on this subject based on the ideXlab platform.
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process for isolation of cardanol from technical cashew Anacardium occidentale l nut shell liquid
Journal of Agricultural and Food Chemistry, 2002Co-Authors: Phani P Kumar, R Paramashivappa, P J Vithayathil, P Subba S V Rao, Srinivasa A RaoAbstract:Commercially available technical cashew (Anacardium occidentale L.) nut shell liquid (CNSL) contains mainly cardanol (decarboxylated anacardic acid) and cardol. Cardanol, the monophenolic component of technical CNSL, is widely used as a synthon for the preparation of a number of polymers and agricultural products. This paper describes the separation of cardanol from toxic cardol. Technical CNSL was dissolved in a mixture of methanol and ammonium hydroxide (8:5) and extracted with hexane to obtain cardanol. The resultant methanolic ammonia layer was extracted with a mixture of ethyl acetate and hexane to yield cardol. This is the first industrially feasible process based on solvent extractions for the isolation of cardanol from technical CNSL.
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process for isolation of cardanol from technical cashew Anacardium occidentale l nut shell liquid
Journal of Agricultural and Food Chemistry, 2002Co-Authors: Pradeep Kumar, R Paramashivappa, P J VithayathilAbstract:Commercially available technical cashew (Anacardium occidentale L.) nut shell liquid (CNSL) contains mainly cardanol (decarboxylated anacardic acid) and cardol. Cardanol, the monophenolic component of technical CNSL, is widely used as a synthon for the preparation of a number of polymers and agricultural products. This paper describes the separation of cardanol from toxic cardol. Technical CNSL was dissolved in a mixture of methanol and ammonium hydroxide (8:5) and extracted with hexane to obtain cardanol. The resultant methanolic ammonia layer was extracted with a mixture of ethyl acetate and hexane to yield cardol. This is the first industrially feasible process based on solvent extractions for the isolation of cardanol from technical CNSL. Keywords: Anacardic acid; cardol; cardanol; cashew nut shell liquid; Anacardium occidentale L.
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novel method for isolation of major phenolic constituents from cashew Anacardium occidentale l nut shell liquid
Journal of Agricultural and Food Chemistry, 2001Co-Authors: R Paramashivappa, Pradeep Kumar, P J VithayathilAbstract:Commercially available cashew (Anacardium occidentale L.) nut shell liquid (CNSL) mainly contains the phenolic constituents anacardic acid, cardol, and cardanol. These phenolic constituents are themselves heterogeneous, and each of them contains saturated, monoene, diene, and trienes in the fifteen-carbon side chain. This communication describes the separation of anacardic acid, cardol, and cardanol for industrial application. Anacardic acid was selectively isolated as calcium anacardate. The acid-free CNSL was treated with liquor ammonia and extracted with hexane/ethyl acetate (98:2) to separate the mono phenolic component, cardanol. Subsequently, ammonia solution was extracted with ethyl acetate/hexane (80:20) to obtain cardol. Keywords: Anacardic acid; cardol; cardanol; calcium salt; cashew nut shell liquid; Anacardium occidentale L.
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novel method for isolation of major phenolic constituents from cashew Anacardium occidentale l nut shell liquid
Journal of Agricultural and Food Chemistry, 2001Co-Authors: R Paramashivappa, P J Vithayathil, Phani P Kumar, A S RaoAbstract:Commercially available cashew (Anacardium occidentale L.) nut shell liquid (CNSL) mainly contains the phenolic constituents anacardic acid, cardol, and cardanol. These phenolic constituents are themselves heterogeneous, and each of them contains saturated, monoene, diene, and trienes in the fifteen-carbon side chain. This communication describes the separation of anacardic acid, cardol, and cardanol for industrial application. Anacardic acid was selectively isolated as calcium anacardate. The acid-free CNSL was treated with liquor ammonia and extracted with hexane/ethyl acetate (98:2) to separate the mono phenolic component, cardanol. Subsequently, ammonia solution was extracted with ethyl acetate/hexane (80:20) to obtain cardol.
B Bicalho - One of the best experts on this subject based on the ideXlab platform.
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application of high temperature gas chromatography mass spectrometry to the investigation of glycosidically bound components related to cashew apple Anacardium occidentale l var nanum volatiles
Journal of Agricultural and Food Chemistry, 2000Co-Authors: B Bicalho, F Aquino R Neto, And A C Pinto, Alberto Dos Santos Pereira, Claudia Moraes De RezendeAbstract:Free and bound volatile components of a Brazilian cashew apple variety (Anacardium occidentale L. var. nanum) were obtained by simultaneous distillation−extraction (SDE) and XAD-2 adsorption. According to gas chromatography−mass spectrometry (GC-MS) analyses and retention indices, 62 free volatile constituents were characterized and quantified. They were esters (40%), terpenes (20%), hydrocarbons (14%), fatty acids (9%), aldehydes (8%), alcohols (3%), lactones (3%), ketones (1%), phenols (1%), and norisoprenoids (1%). The glycosidically bound volatile precursors were analyzed by high-temperature GC-MS, after room temperature silylation. Several conjugated alcohols and cinnamic acids were detected and reported as cashew apple glycosyl constituents for the first time. Keywords: Cashew apple; Anacardium occidentale L.; volatile compounds; glycoside; high-temperature gas chromatography
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application of high temperature gas chromatography mass spectrometry to the investigation of glycosidically bound components related to cashew apple Anacardium occidentale l var nanum volatiles
Journal of Agricultural and Food Chemistry, 2000Co-Authors: B Bicalho, F Aquino R Neto, And A C Pinto, Alberto Dos Santos Pereira, Claudia Moraes De RezendeAbstract:Free and bound volatile components of a Brazilian cashew apple variety (Anacardium occidentale L. var. nanum) were obtained by simultaneous distillation-extraction (SDE) and XAD-2 adsorption. According to gas chromatography-mass spectrometry (GC-MS) analyses and retention indices, 62 free volatile constituents were characterized and quantified. They were esters (40%), terpenes (20%), hydrocarbons (14%), fatty acids (9%), aldehydes (8%), alcohols (3%), lactones (3%), ketones (1%), phenols (1%), and norisoprenoids (1%). The glycosidically bound volatile precursors were analyzed by high-temperature GC-MS, after room temperature silylation. Several conjugated alcohols and cinnamic acids were detected and reported as cashew apple glycosyl constituents for the first time.
Isao Kubo - One of the best experts on this subject based on the ideXlab platform.
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multifunctional cytotoxic agents from Anacardium occidentale
Phytotherapy Research, 2011Co-Authors: Isao Kubo, Felismino E. Tocoli, Teruhiko Nitoda, Ivan R GreenAbstract:The effects of anacardic acids and cardols isolated from the cashew nut and apple Anacardium occidentale (Anacardiaceae) on murine B16-F10 melanoma cells were tested. Although anacardic acids and cardols were found to inhibit tyrosinase, a key enzyme in melanin synthesis, melanogenesis in melanocytes was not suppressed in cultured cells but rather enhanced. Both anacardic acids and cardols exhibited moderate cytotoxicity. Copyright © 2010 John Wiley & Sons, Ltd.
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tyrosinase inhibitors from Anacardium occidentale fruits
Journal of Natural Products, 1994Co-Authors: Isao Kubo, Ikuyo Kinsthori, Yoshihiro YokokawaAbstract:: Anacardic acids, 2-methylcardols, and cardols isolated from various parts of the cashew [Anacardium occidentale] (Anacardiaceae) fruit have been found to exhibit tyrosinase inhibitory activity. Kinetic studies with the two principal active compounds, 6-[8(Z),11(Z),14-pentadecatrienyl]salicylic acid and 5-[8(Z),11(Z),14-pentadecatrienyl]resorcinol, have indicated that both of these phenolic compounds exhibit characteristic competitive inhibition of the oxidation of L-3,4-dihydroxyphenylalanine (L-DOPA) by mushroom tyrosinase.
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antitumor agents from the cashew Anacardium occidentale apple juice
Journal of Agricultural and Food Chemistry, 1993Co-Authors: Isao Kubo, Masamitsu Ochi, Paulo C. Vieira, Sakae KomatsuAbstract:Three anacardic acids (1-3) have been isolated as cytotoxic agents against BT-20 breast carcinoma cells from the cashew Anacardium occidentale (Anacardiaceae) apple juice. In addition to these anacardic acids, the cytotoxicity of their 13 congeners (4-16) isolated from the cashew nut and nut shell oil has also been examined. Anacardic acids (1-4), cardols (5-8), and methylcardols (9-12) have been found to exhibit moderate cytotoxic activity against both BT-20 breast and HeLa epithelioid cervix carcinoma cells
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antibacterial agents from the cashew Anacardium occidentale anacardiaceae nut shell oil
Journal of Agricultural and Food Chemistry, 1991Co-Authors: Masaki Himejima, Isao KuboAbstract:Sixteen phenolic compounds have been isolated from the cashew Anacardium occidentale (Anacardiaceae) nut shell oil. Their antimicrobial activity has been tested against four typical microorganisms, Bacillus subtilis, a Gram-positive bacterium; Escherichia coli, a Gram-negative bacterium; Saccharomyces cerevisiae, a yeast; and Penicillium chrysogenum, a mold. Most of them exhibited potent antibacterial activity against only Gram-positive bacteria, among which Streptococcus mutans, one of several bacteria responsible for tooth decay, and Propionibacterium acnes, one of the bacteria responsible for acne, were the most sensitive bacteria. Anacardic acids also showed weak activity against molds. Their structure-activity relationships are also described.
Muraleedharan G Nair - One of the best experts on this subject based on the ideXlab platform.
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hypoglycaemic effect of stigmast 4 en 3 one and its corresponding alcohol from the bark of Anacardium occidentale cashew
Phytotherapy Research, 2004Co-Authors: Ruby Alexanderlindo, E Y St A Morrison, Muraleedharan G NairAbstract:Intravenous administration of the hexane extract of the bark of Anacardium occidentale (cashew) in normal, healthy dogs produced a significant lowering of the blood glucose levels. Pursuit of the hypoglycaemic principle(s) in the hexane extract resulted in the isolation and characterization of two compounds, stigmast-4-en-3-ol (1) and stigmast-4-en-3-one (2). These compounds were purified by chromatographic methods and the structures were characterized by spectroscopic methods. Both compounds produced significant hypoglycaemic activity after intravenous administration at a dose of 1.3 mg/kg body weight. The bark of the cashew plant, A. occidentale, exhibited a hypoglycaemic effect probably due to the presence of these compounds.
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hypoglycaemic effect of stigmast 4 en 3 one and its corresponding alcohol from the bark of Anacardium occidentale cashew
Phytotherapy Research, 2004Co-Authors: Ruby Alexanderlindo, E Y St A Morrison, Muraleedharan G NairAbstract:Intravenous administration of the hexane extract of the bark of Anacardium occidentale (cashew) in normal, healthy dogs produced a significant lowering of the blood glucose levels. Pursuit of the hypoglycaemic principle(s) in the hexane extract resulted in the isolation and characterization of two compounds, stigmast-4-en-3-ol (1) and stigmast-4-en-3-one (2). These compounds were purified by chromatographic methods and the structures were characterized by spectroscopic methods. Both compounds produced significant hypoglycaemic activity after intravenous administration at a dose of 1.3 mg/kg body weight. The bark of the cashew plant, A. occidentale, exhibited a hypoglycaemic effect probably due to the presence of these compounds. Copyright © 2004 John Wiley & Sons, Ltd.