The Experts below are selected from a list of 222 Experts worldwide ranked by ideXlab platform
Kuang-hua Chang - One of the best experts on this subject based on the ideXlab platform.
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Mechanism Design With Creo Elements/Pro 5.0:
2011Co-Authors: Kuang-hua ChangAbstract:Mechanism Design with Creo Elements/Pro 5.0 is designed to help you become familiar with Mechanism Design, a module in the Creo Elements/Pro (formerly Pro/ENGINEER) software family, which supports modeling and Analysis (or simulation) of mechanisms in a virtual (computer) environment. Capabilities in Mechanism Design allow users to simulate and visualize mechanism performance. Using Mechanism Design early in the product development stage could prevent costly redesign due to design defects found in the physical testing phase; therefore, contributing to a more cost effective, reliable, and efficient product development process. The book is written following a project-based learning approach and covers the major concepts and frequently used commands required to advance readers from a novice to an intermediate level. Basic concepts discussed include: model creation, such as body and joint definitions; Analysis Type selection, such as static (assembly) Analysis, kinematics and dynamics; and results visualization. The concepts are introduced using simple, yet realistic, examples. Verifying the results obtained from computer simulation is extremely important. One of the unique features of this textbook is the incorporation of theoretical discussions for kinematic and dynamic analyses in conjunction with simulation results obtained using Mechanism Design. The theoretical discussions simply support the verification of simulation results rather than providing an in-depth discussion on the subjects of kinematics and dynamics. Table of Contents 1. Introduction to Mechanism Design 2. The Ball Throwing Example 3. A Spring Mass System 4. A Simple Pendulum 5. A Slider-Crank Mechanism - Static and Motion Analysis 6. A Compound Spur Gear Train 7. Planetary Gear Train Systems 8. Cam and Follower 9. Assistive Device for Wheelchair Soccer Game 10. Kinematic Analysis for Racecar Suspension Appendix A: Defining Joints Appendix B: Defining Measures Appendix C: The Default Unit System Appendix D: The Magnitude Settings
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mechanism design with creo elements pro 5 0
2011Co-Authors: Kuang-hua ChangAbstract:Mechanism Design with Creo Elements/Pro 5.0 is designed to help you become familiar with Mechanism Design, a module in the Creo Elements/Pro (formerly Pro/ENGINEER) software family, which supports modeling and Analysis (or simulation) of mechanisms in a virtual (computer) environment. Capabilities in Mechanism Design allow users to simulate and visualize mechanism performance. Using Mechanism Design early in the product development stage could prevent costly redesign due to design defects found in the physical testing phase; therefore, contributing to a more cost effective, reliable, and efficient product development process. The book is written following a project-based learning approach and covers the major concepts and frequently used commands required to advance readers from a novice to an intermediate level. Basic concepts discussed include: model creation, such as body and joint definitions; Analysis Type selection, such as static (assembly) Analysis, kinematics and dynamics; and results visualization. The concepts are introduced using simple, yet realistic, examples. Verifying the results obtained from computer simulation is extremely important. One of the unique features of this textbook is the incorporation of theoretical discussions for kinematic and dynamic analyses in conjunction with simulation results obtained using Mechanism Design. The theoretical discussions simply support the verification of simulation results rather than providing an in-depth discussion on the subjects of kinematics and dynamics. Table of Contents 1. Introduction to Mechanism Design 2. The Ball Throwing Example 3. A Spring Mass System 4. A Simple Pendulum 5. A Slider-Crank Mechanism - Static and Motion Analysis 6. A Compound Spur Gear Train 7. Planetary Gear Train Systems 8. Cam and Follower 9. Assistive Device for Wheelchair Soccer Game 10. Kinematic Analysis for Racecar Suspension Appendix A: Defining Joints Appendix B: Defining Measures Appendix C: The Default Unit System Appendix D: The Magnitude Settings
Joseph Salmon - One of the best experts on this subject based on the ideXlab platform.
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Stable Recovery with Analysis Decomposable Priors
2017Co-Authors: Jalal M. Fadili, Samuel Vaiter, Charles Alban Deledalle, Gabriel Peyré, Joseph SalmonAbstract:In this paper, we investigate in a unified way the structural properties of solutions to inverse problems regularized by the generic class of semi-norms defined as a decomposable norm composed with a linear operator, the so-called Analysis decomposable prior. This encompasses several well-known Analysis-Type regularizations such as the discrete total variation, Analysis group-Lasso or the nuclear norm. Our main results establish sufficient conditions under which uniqueness and stability to a bounded noise of the regularized solution are guaranteed.
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Stable Recovery with Analysis Decomposable Priors
arXiv: Information Theory, 2013Co-Authors: M. J. Fadili, Charles Alban Deledalle, Samuel Vaiter, Gabriel Peyré, Joseph SalmonAbstract:In this paper, we investigate in a unified way the structural properties of solutions to inverse problems. These solutions are regularized by the generic class of semi-norms defined as a decomposable norm composed with a linear operator, the so-called Analysis Type decomposable prior. This encompasses several well-known Analysis-Type regularizations such as the discrete total variation (in any dimension), Analysis group-Lasso or the nuclear norm. Our main results establish sufficient conditions under which uniqueness and stability to a bounded noise of the regularized solution are guaranteed. Along the way, we also provide a strong sufficient uniqueness result that is of independent interest and goes beyond the case of decomposable norms.
Richard Jude Samulski - One of the best experts on this subject based on the ideXlab platform.
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cross packaging of a single adeno associated virus aav Type 2 vector genome into multiple aav seroTypes enables transduction with broad specificity
Journal of Virology, 2002Co-Authors: Joseph E Rabinowitz, F Rolling, H Conrath, Weidong Xiao, Chengwen Li, Xiao Xiao, Richard Jude SamulskiAbstract:The seroTypes of adeno-associated virus (AAV) have the potential to become important resources for clinical gene therapy. In an effort to compare the role of seroType-specific virion shells on vector transduction, we cloned each of the seroType capsid coding domains into a common vector backbone containing AAV Type 2 replication genes. This strategy allowed the packaging of AAV2 inverted terminal repeat vectors into each seroType-specific virions. Each of these helper plasmids (pXR1 through pXR5) efficiently replicated the transgene DNA and expressed helper proteins at nearly equivalent levels. In this study, we observed a correlation between the amount of transgene replication and packaging efficiency. The physical titer of these hybrid vectors ranged between 1.3 × 1011 and 9.8 × 1012/ml (Types 1 and 2, respectively). Of the five seroType vectors, only Types 2 and 3 were efficiently purified by heparin-Sepharose column chromatography, illustrating the high degree of similarity between these virions. We analyzed vector transduction in reference and mutant Chinese hamster ovary cells deficient in heparan sulfate proteoglycan and saw a correlation between transduction and heparan sulfate binding data. In this Analysis, Types 1 and 5 were most consistent in transduction efficiency across all cell lines tested. In vivo each seroType was ranked after comparison of transgene levels by using different routes of injection and strains of rodents. Overall, in this Analysis, Type 1 was superior for efficient transduction of liver and muscle, followed in order by Types 5, 3, 2, and 4. Surprisingly, this order changed when vector was introduced into rat retina. Types 5 and 4 were most efficient, followed by Type 1. These data established a hierarchy for efficient seroType-specific vector transduction depending on the target tissue. These data also strongly support the need for extending these analyses to additional animal models and human tissue. The development of these helper plasmids should facilitate direct comparisons of seroTypes, as well as begin the standardization of production for further clinical development.
Kato S - One of the best experts on this subject based on the ideXlab platform.
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The standard level of IgE RIST and eosinophil counts in 0-year old allergic children according to multiple factor Analysis Type II
Arerugī (Allergy), 1990Co-Authors: Kato SAbstract:We specified three standard levels of IgE RIST (10, 20, 60 IU/ml) for the ninety-four (94) allergic clients of 0-year infants, who classified with three groups. Each group was furthermore divided in two groups such as a group under the standard level and a group exceeding the level respectively. Next, using the Multiple Factor Analysis Type II, we examined quantitative Analysis that each of three classified groups was influenced on 12 allergic factors of sex, existence and inexistence of wheezing and atopic dermatitis, family history of allergic diseases, eosinophil counts. IgE RAST scores and antibody titers against egg white, milk and soybean, IgE RAST scores to Dermatophagoides farinae, while the we discussed how the standard levels were adequately reacted to the Analysis. As a results, strong allergic factors which influenced the three groups commonly were two factors of IgE RAST scores to egg white and D.f. In particular, the factor which influenced the group of 10 IU/ml standard level was eosinophil counts and family history of allergic diseases. Furthermore, the strong factors which influenced the group classified on 60 IU/ml standard outstandingly appeared in IgE RAST scores to soybean, however, we did not find any difference between three groups. On the other hand, when we specified the standard level at 100/mm3, 200/mm3, 400/mm3 in regard to the eosinophil counts under the same method and examined results, we found strong allergic factors which influenced family history of allergic diseases. IgE RAST scores to egg white and soybean. However, the study scarcely recognize any difference between the three groups.
Roger Toogood - One of the best experts on this subject based on the ideXlab platform.
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Pro/ENGINEER Wildfire 5.0 Mechanica Tutorial (Structure/Thermal)
2009Co-Authors: Roger ToogoodAbstract:Pro/ENGINEER Wildfire 5.0 Mechanica Tutorial (Structure/Thermal) introduces new users to finite element Analysis using Pro/ENGINEER Mechanica and how it can be used to analyze a variety of problems. The tutorial lessons cover the major concepts and frequently used commands required to progress from a novice to an intermediate user level. The commands are presented in a click-by-click manner using simple examples and exercises that illustrate a broad range of the Analysis Types that can be performed. In addition to showing the command usage, the text will explain why certain commands are being used and, where appropriate, the relation of commands to the overall FEA philosophy are explained. Moreover, since error Analysis is an important skill, considerable time is spent exploring the created models so that users will become comfortable with the debugging phase of modeling. This textbook is written for first-time FEA users (in general) and MECHANICA users (in particular). After a brief introduction to finite element modeling, the tutorial introduces the major concepts behind the use of Pro/MECHANICA to perform Finite Element Analysis of parts. These include: modes of operation, element Types, design studies (Analysis, sensitivity studies, organization), and the major steps for setting up a model (materials, loads, constraints, Analysis Type), studying convergence of the solution, and viewing the results. Both 2D and 3D problems are treated. Table of Contents 1. Introduction to the Tutorials 2. Finite Element Modeling with MECHANICA 3. Solid Models (Part 1) 4. Solid Models (Part 2) 5. Plane Stress and Plane Strain Models 6. Axisymmetric Solids and Shells 7. Shell Models 8. Beams and Frames 9. Miscellaneous Topics 10. Thermal Models
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Pro/ENGINEER Wildfire 4.0 Mechanica Tutorial (Structure/Thermal)
2008Co-Authors: Roger ToogoodAbstract:Pro/ENGINEER Wildfire 4.0 Mechanica Tutorial (Structure/Thermal) introduces new users to finite element Analysis using Pro/ENGINEER Mechanica and how it can be used to analyze a variety of problems. The tutorial lessons cover the major concepts and frequently used commands required to progress from a novice to an intermediate user level. The commands are presented in a click-by-click manner using simple examples and exercises that illustrate a broad range of the Analysis Types that can be performed. In addition to showing the command usage, the text will explain why certain commands are being used and, where appropriate, the relation of commands to the overall FEA philosophy are explained. Moreover, since error Analysis is an important skill, considerable time is spent exploring the created models so that users will become comfortable with the debugging phase of modeling. This book is written for first-time FEA users (in general) and MECHANICA users (in particular). After a brief introduction to finite element modeling, the tutorial introduces the major concepts behind the use of Pro/MECHANICA to perform Finite Element Analysis of parts. These include: modes of operation, element Types, design studies (Analysis, sensitivity studies, organization), and the major steps for setting up a model (materials, loads, constraints, Analysis Type), studying convergence of the solution, and viewing the results. Both 2D and 3D problems are treated. Table of Contents 1. Introduction to the Tutorials 2. Finite Element Modeling with MECHANICA 3. Solid Models (Part 1) 4. Solid Models (Part 2) 5. Plane Stress and Plane Strain Models 6. Axisymmetric Solids and Shells 7. Shell Models 8. Beams and Frames 9. Miscellaneous Topics 10. Thermal Models
