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Sheila Riazi - One of the best experts on this subject based on the ideXlab platform.

Natalia Kraeva - One of the best experts on this subject based on the ideXlab platform.

Marilyn Green Larach - One of the best experts on this subject based on the ideXlab platform.

Gabriel Gastaminza - One of the best experts on this subject based on the ideXlab platform.

  • Early skin testing is effective for diagnosis of hypersensitivity Reactions occurring during anesthesia.
    Allergy, 2013
    Co-Authors: Alberto Lafuente, Gracia Javaloyes, Felicia Berroa, Maria Jose Goikoetxea, Rafael Moncada, Jorge M. Núñez-córdoba, Paula Cabrera-freitag, Carmen M. D'amelio, Maria L. Sanz, Gabriel Gastaminza
    Abstract:

    Allergic skin tests have to be performed 4–6 weeks after an allergic Anesthetic Reaction. Patients with allergic Reactions during anesthesia were prospectively included (n = 44). Skin tests were performed in two stages: (i) Stage 1 (S1), 0–4 days after the Reaction; and (ii) Stage 2 (S2), 4–8 weeks after. Five (11.5%) surgical procedures were suspended due to the Reaction. Positive skin tests were obtained in 25/44 patients (57%). Allergic diagnosis was carried out at S1 in 15/25 (60%) and at S2 in 10/25 (40%). Three patients resulted positive only in S1. Overall agreement among S1 and S2 skin tests was 70.45%. The kappa statistic was 0.41 (P-value = 0.002). Odds ratio of obtaining a false negative in S1 (compared with S2) was 3.33. Early allergological study is useful, could minimize false negatives, but should be considered as a complement to late skin tests.

Carly Sterling - One of the best experts on this subject based on the ideXlab platform.