The Experts below are selected from a list of 360 Experts worldwide ranked by ideXlab platform

Vincent Walsh - One of the best experts on this subject based on the ideXlab platform.

  • the Angular Gyrus and visuospatial attention in decision making under risk
    NeuroImage, 2014
    Co-Authors: Bettina Studer, Danlu Cen, Vincent Walsh
    Abstract:

    Recent neuroimaging studies on decision-making under risk indicate that the Angular Gyrus (AG) is sensitive to the probability and variance of outcomes during choice. A separate body of research has established the AG as a key area in visual attention. The current study used repetitive transcranial magnetic stimulation (rTMS) in healthy volunteers to test whether the causal contribution of the AG to decision-making is independent of or linked to the guidance of visuospatial attention. A within-subject design compared decision making on a laboratory gambling task under three conditions: following rTMS to the AG, following rTMS to the premotor cortex (PMC, as an active control condition) and without TMS. The task presented two different trial types, ‘visual’ and ‘auditory’ trials, which entailed a high versus minimal demand for visuospatial attention, respectively. Our results showed a systematic effect of rTMS to the AG upon decision-making behavior in visual trials. Without TMS and following rTMS to the control region, decision latencies reflected the odds of winning; this relationship was disrupted by rTMS to the AG. In contrast, no significant effects of rTMS to the AG (or to the PMC) upon choice behavior in auditory trials were found. Thus, rTMS to the AG affected decision-making only in the task condition requiring visuospatial attention. The current findings suggest that the AG contributes to decision-making by guiding attention to relevant information about reward and punishment in the visual environment.

  • the role of the Angular Gyrus in visual conjunction search investigated using signal detection analysis and transcranial magnetic stimulation
    Neuropsychologia, 2008
    Co-Authors: Neil G Muggleton, Alan Cowey, Vincent Walsh
    Abstract:

    Transcranial magnetic stimulation (TMS) delivered over the posterior parietal cortex increases choice reaction times in visual search for a target defined by a conjunction of features. Some recent studies of visual search have taken an approach based on signal detection theory, the findings of which are not addressed by studying the disruptive effects of TMS on reaction time. Here we investigated the role of the posterior parietal cortex in visual search by applying TMS while subjects performed unspeeded feature and conjunction visual search tasks matched for level of difficulty. TMS over the right, but not the left Angular Gyrus (AG) in the parietal cortex, nor vertex decreased subjects' sensitivity on the conjunction but not the feature search task, as measured by the signal detection measure, d'. Changes in bias, specifically the tendency to make false positive responses, were less clear. We consider the findings in terms of four possible explanation: binding, attentional control, spatial localisation and visuomotor co-ordinate transformations.

  • dexterity with numbers rtms over left Angular Gyrus disrupts finger gnosis and number processing
    Neuropsychologia, 2005
    Co-Authors: Elena Rusconi, Vincent Walsh, Brian Butterworth
    Abstract:

    Since the original description of Gerstmann's syndrome with its four cardinal symptoms, among which are finger agnosia and acalculia, the neuro-cognitive relationship between fingers and calculation has been debated. We asked our participants to perform four different tasks, two of which involved fingers and the other two involving numbers, during repetitive transcranial magnetic stimulation (rTMS) over the posterior parietal lobe of either hemisphere. In the finger tasks, they were required to transform a tactile stimulus randomly delivered on one of their fingers into a speeded key-press response either with the same or with the homologous finger on the opposite hand. In the numerical tasks, they were asked to perform a magnitude or a parity matching on pairs of single digits, in the context of arithmetically related or unrelated numerical primes. In accordance with the original anatomical hypothesis put forward by Gerstmann [Gerstmann, J. (1924). Fingeragnosie: eine umschriebene Stoerung der Orienterung am eigenen Koerper. Wiener clinische Wochenschrift, 37, 1010–12], we found that rTMS over the left Angular Gyrus disrupted tasks requiring access to the finger schema and number magnitude processing in the same group of participants. In addition to the numerous studies which have employed special populations such as neurological patients and children, our data confirm the presence of a relationship between numbers and body knowledge in skilled adults who no longer use their fingers for solving simple arithmetical tasks.

  • The mental number line and the human Angular Gyrus.
    NeuroImage, 2001
    Co-Authors: Silke M. Göbel, Vincent Walsh, Matthew F. S. Rushworth
    Abstract:

    To investigate the hemispheric organization of a language-independent spatial representation of number magnitude in the human brain we applied focal repetitive transcranial magnetic stimulation (rTMS) to the right or left Angular Gyrus while subjects performed a number comparison task with numbers between 31 and 99. Repetitive TMS over the Angular Gyrus disrupted performance of a visuospatial search task, and rTMS at the same site disrupted organization of the putative “number line.” In some cases the pattern of disruption caused by Angular Gyrus rTMS suggested that this area normally mediates a spatial representation of number. The effect of Angular Gyrus rTMS on the number line task was specific. rTMS had no disruptive effect when delivered over another parietal region, the supramarginal Gyrus, in either the left or the right hemisphere.

Roberto Cavazosrodriguez - One of the best experts on this subject based on the ideXlab platform.

  • music reduces pain and increases resting state fmri bold signal amplitude in the left Angular Gyrus in fibromyalgia patients
    Frontiers in Psychology, 2015
    Co-Authors: Eduardo A Garzavillarreal, Zhiguo Jiang, Peter Vuust, Sarael Alcauter, Lene Vase, Erick H Pasaye, Roberto Cavazosrodriguez
    Abstract:

    Music reduces pain in fibromyalgia (FM), a chronic pain disease, but the functional neural correlates of music-induced analgesia are still largely unknown. We recruited FM patients (n = 22) who listened to their preferred relaxing music and an auditory control (pink noise) for 5 minutes without external noise from fMRI image acquisition. Resting state fMRI was then acquired before and after the music and control conditions. A significant increase in the amplitude of low frequency fluctuations of the BOLD signal was evident in the left Angular Gyrus after listening to music, which in turn, correlated to the analgesia reports. The post-hoc seed-based functional connectivity analysis of the left Angular Gyrus showed found higher connectivity after listening to music with right dorsolateral prefrontal cortex, the left caudate, and decreased connectivity with right anterior cingulate cortex, right supplementary motor area, precuneus and right precentral Gyrus. Pain intensity analgesia was correlated (r = .61) to the connectivity of the left Angular Gyrus with the right precentral Gyrus. Our results show that music-induced analgesia in FM is related to top-down regulation of the pain modulatory network by the default-mode network.

  • music reduces pain and increases resting state fmri bold signal amplitude in the left Angular Gyrus in fibromyalgia patients
    Frontiers in Psychology, 2015
    Co-Authors: Eduardo A Garzavillarreal, Zhiguo Jiang, Peter Vuust, Sarael Alcauter, Lene Vase, Erick H Pasaye, Roberto Cavazosrodriguez
    Abstract:

    Music reduces pain in fibromyalgia (FM), a chronic pain disease, but the functional neural correlates of music-induced analgesia (MIA) are still largely unknown. We recruited FM patients (n = 22) who listened to their preferred relaxing music and an auditory control (pink noise) for 5 min without external noise from fMRI image acquisition. Resting state fMRI was then acquired before and after the music and control conditions. A significant increase in the amplitude of low frequency fluctuations of the BOLD signal was evident in the left Angular Gyrus (lAnG) after listening to music, which in turn, correlated to the analgesia reports. The post-hoc seed-based functional connectivity analysis of the lAnG showed found higher connectivity after listening to music with right dorsolateral prefrontal cortex (rdlPFC), the left caudate (lCau), and decreased connectivity with right anterior cingulate cortex (rACC), right supplementary motor area (rSMA), precuneus and right precentral Gyrus (rPreG). Pain intensity (PI) analgesia was correlated (r = 0.61) to the connectivity of the lAnG with the rPreG. Our results show that MIA in FM is related to top-down regulation of the pain modulatory network by the default mode network (DMN).

Peter Vuust - One of the best experts on this subject based on the ideXlab platform.

  • music reduces pain and increases resting state fmri bold signal amplitude in the left Angular Gyrus in fibromyalgia patients
    Frontiers in Psychology, 2015
    Co-Authors: Eduardo A Garzavillarreal, Zhiguo Jiang, Peter Vuust, Sarael Alcauter, Lene Vase, Erick H Pasaye, Roberto Cavazosrodriguez
    Abstract:

    Music reduces pain in fibromyalgia (FM), a chronic pain disease, but the functional neural correlates of music-induced analgesia are still largely unknown. We recruited FM patients (n = 22) who listened to their preferred relaxing music and an auditory control (pink noise) for 5 minutes without external noise from fMRI image acquisition. Resting state fMRI was then acquired before and after the music and control conditions. A significant increase in the amplitude of low frequency fluctuations of the BOLD signal was evident in the left Angular Gyrus after listening to music, which in turn, correlated to the analgesia reports. The post-hoc seed-based functional connectivity analysis of the left Angular Gyrus showed found higher connectivity after listening to music with right dorsolateral prefrontal cortex, the left caudate, and decreased connectivity with right anterior cingulate cortex, right supplementary motor area, precuneus and right precentral Gyrus. Pain intensity analgesia was correlated (r = .61) to the connectivity of the left Angular Gyrus with the right precentral Gyrus. Our results show that music-induced analgesia in FM is related to top-down regulation of the pain modulatory network by the default-mode network.

  • music reduces pain and increases resting state fmri bold signal amplitude in the left Angular Gyrus in fibromyalgia patients
    Frontiers in Psychology, 2015
    Co-Authors: Eduardo A Garzavillarreal, Zhiguo Jiang, Peter Vuust, Sarael Alcauter, Lene Vase, Erick H Pasaye, Roberto Cavazosrodriguez
    Abstract:

    Music reduces pain in fibromyalgia (FM), a chronic pain disease, but the functional neural correlates of music-induced analgesia (MIA) are still largely unknown. We recruited FM patients (n = 22) who listened to their preferred relaxing music and an auditory control (pink noise) for 5 min without external noise from fMRI image acquisition. Resting state fMRI was then acquired before and after the music and control conditions. A significant increase in the amplitude of low frequency fluctuations of the BOLD signal was evident in the left Angular Gyrus (lAnG) after listening to music, which in turn, correlated to the analgesia reports. The post-hoc seed-based functional connectivity analysis of the lAnG showed found higher connectivity after listening to music with right dorsolateral prefrontal cortex (rdlPFC), the left caudate (lCau), and decreased connectivity with right anterior cingulate cortex (rACC), right supplementary motor area (rSMA), precuneus and right precentral Gyrus (rPreG). Pain intensity (PI) analgesia was correlated (r = 0.61) to the connectivity of the lAnG with the rPreG. Our results show that MIA in FM is related to top-down regulation of the pain modulatory network by the default mode network (DMN).

Lene Vase - One of the best experts on this subject based on the ideXlab platform.

  • music reduces pain and increases resting state fmri bold signal amplitude in the left Angular Gyrus in fibromyalgia patients
    Frontiers in Psychology, 2015
    Co-Authors: Eduardo A Garzavillarreal, Zhiguo Jiang, Peter Vuust, Sarael Alcauter, Lene Vase, Erick H Pasaye, Roberto Cavazosrodriguez
    Abstract:

    Music reduces pain in fibromyalgia (FM), a chronic pain disease, but the functional neural correlates of music-induced analgesia are still largely unknown. We recruited FM patients (n = 22) who listened to their preferred relaxing music and an auditory control (pink noise) for 5 minutes without external noise from fMRI image acquisition. Resting state fMRI was then acquired before and after the music and control conditions. A significant increase in the amplitude of low frequency fluctuations of the BOLD signal was evident in the left Angular Gyrus after listening to music, which in turn, correlated to the analgesia reports. The post-hoc seed-based functional connectivity analysis of the left Angular Gyrus showed found higher connectivity after listening to music with right dorsolateral prefrontal cortex, the left caudate, and decreased connectivity with right anterior cingulate cortex, right supplementary motor area, precuneus and right precentral Gyrus. Pain intensity analgesia was correlated (r = .61) to the connectivity of the left Angular Gyrus with the right precentral Gyrus. Our results show that music-induced analgesia in FM is related to top-down regulation of the pain modulatory network by the default-mode network.

  • music reduces pain and increases resting state fmri bold signal amplitude in the left Angular Gyrus in fibromyalgia patients
    Frontiers in Psychology, 2015
    Co-Authors: Eduardo A Garzavillarreal, Zhiguo Jiang, Peter Vuust, Sarael Alcauter, Lene Vase, Erick H Pasaye, Roberto Cavazosrodriguez
    Abstract:

    Music reduces pain in fibromyalgia (FM), a chronic pain disease, but the functional neural correlates of music-induced analgesia (MIA) are still largely unknown. We recruited FM patients (n = 22) who listened to their preferred relaxing music and an auditory control (pink noise) for 5 min without external noise from fMRI image acquisition. Resting state fMRI was then acquired before and after the music and control conditions. A significant increase in the amplitude of low frequency fluctuations of the BOLD signal was evident in the left Angular Gyrus (lAnG) after listening to music, which in turn, correlated to the analgesia reports. The post-hoc seed-based functional connectivity analysis of the lAnG showed found higher connectivity after listening to music with right dorsolateral prefrontal cortex (rdlPFC), the left caudate (lCau), and decreased connectivity with right anterior cingulate cortex (rACC), right supplementary motor area (rSMA), precuneus and right precentral Gyrus (rPreG). Pain intensity (PI) analgesia was correlated (r = 0.61) to the connectivity of the lAnG with the rPreG. Our results show that MIA in FM is related to top-down regulation of the pain modulatory network by the default mode network (DMN).

Zhiguo Jiang - One of the best experts on this subject based on the ideXlab platform.

  • music reduces pain and increases resting state fmri bold signal amplitude in the left Angular Gyrus in fibromyalgia patients
    Frontiers in Psychology, 2015
    Co-Authors: Eduardo A Garzavillarreal, Zhiguo Jiang, Peter Vuust, Sarael Alcauter, Lene Vase, Erick H Pasaye, Roberto Cavazosrodriguez
    Abstract:

    Music reduces pain in fibromyalgia (FM), a chronic pain disease, but the functional neural correlates of music-induced analgesia are still largely unknown. We recruited FM patients (n = 22) who listened to their preferred relaxing music and an auditory control (pink noise) for 5 minutes without external noise from fMRI image acquisition. Resting state fMRI was then acquired before and after the music and control conditions. A significant increase in the amplitude of low frequency fluctuations of the BOLD signal was evident in the left Angular Gyrus after listening to music, which in turn, correlated to the analgesia reports. The post-hoc seed-based functional connectivity analysis of the left Angular Gyrus showed found higher connectivity after listening to music with right dorsolateral prefrontal cortex, the left caudate, and decreased connectivity with right anterior cingulate cortex, right supplementary motor area, precuneus and right precentral Gyrus. Pain intensity analgesia was correlated (r = .61) to the connectivity of the left Angular Gyrus with the right precentral Gyrus. Our results show that music-induced analgesia in FM is related to top-down regulation of the pain modulatory network by the default-mode network.

  • music reduces pain and increases resting state fmri bold signal amplitude in the left Angular Gyrus in fibromyalgia patients
    Frontiers in Psychology, 2015
    Co-Authors: Eduardo A Garzavillarreal, Zhiguo Jiang, Peter Vuust, Sarael Alcauter, Lene Vase, Erick H Pasaye, Roberto Cavazosrodriguez
    Abstract:

    Music reduces pain in fibromyalgia (FM), a chronic pain disease, but the functional neural correlates of music-induced analgesia (MIA) are still largely unknown. We recruited FM patients (n = 22) who listened to their preferred relaxing music and an auditory control (pink noise) for 5 min without external noise from fMRI image acquisition. Resting state fMRI was then acquired before and after the music and control conditions. A significant increase in the amplitude of low frequency fluctuations of the BOLD signal was evident in the left Angular Gyrus (lAnG) after listening to music, which in turn, correlated to the analgesia reports. The post-hoc seed-based functional connectivity analysis of the lAnG showed found higher connectivity after listening to music with right dorsolateral prefrontal cortex (rdlPFC), the left caudate (lCau), and decreased connectivity with right anterior cingulate cortex (rACC), right supplementary motor area (rSMA), precuneus and right precentral Gyrus (rPreG). Pain intensity (PI) analgesia was correlated (r = 0.61) to the connectivity of the lAnG with the rPreG. Our results show that MIA in FM is related to top-down regulation of the pain modulatory network by the default mode network (DMN).