Ankle Brachial Index

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Yasushi Kita - One of the best experts on this subject based on the ideXlab platform.

Kazumi Kimura - One of the best experts on this subject based on the ideXlab platform.

Sonia S Anand - One of the best experts on this subject based on the ideXlab platform.

Richard A. Kronmal - One of the best experts on this subject based on the ideXlab platform.

  • Incidence and predictors of clinical peripheral artery disease in asymptomatic persons with a low AnkleBrachial Index:
    Journal of Medical Screening, 2018
    Co-Authors: Noel S Weiss, Michael H. Criqui, Robyn L Mcclelland, Christina L Wassel, Richard A. Kronmal
    Abstract:

    ObjectiveTo determine the occurrence of clinical peripheral artery disease in a cohort of middle-aged and older persons who, though they initially had no symptoms of peripheral artery disease, had blood pressure levels in the arteries of their Ankles and feet that were at least 10% lower than those in the arteries of their arms.MethodsWe analyzed data obtained in the Multi-Ethnic Study of Atherosclerosis, in which lower and upper extremity blood pressures were assessed in over 6000 Americans aged 45–84 and the ratio of these (the AnkleBrachial Index) was calculated. During a median follow-up of 13 years, the incidence of symptomatic peripheral artery disease (identified through annual questionnaires, review of hospital records, and notations of peripheral artery disease found in data obtained from the Center for Medicare Services) was compared between persons whose AnkleBrachial Index was ⩽9 and persons with higher AnkleBrachial Index values.ResultsThe incidence of clinical peripheral artery disease wa...

  • incidence and predictors of clinical peripheral artery disease in asymptomatic persons with a low Ankle Brachial Index
    Journal of Medical Screening, 2018
    Co-Authors: Noel S Weiss, Michael H. Criqui, Robyn L Mcclelland, Christina L Wassel, Richard A. Kronmal
    Abstract:

    ObjectiveTo determine the occurrence of clinical peripheral artery disease in a cohort of middle-aged and older persons who, though they initially had no symptoms of peripheral artery disease, had blood pressure levels in the arteries of their Ankles and feet that were at least 10% lower than those in the arteries of their arms.MethodsWe analyzed data obtained in the Multi-Ethnic Study of Atherosclerosis, in which lower and upper extremity blood pressures were assessed in over 6000 Americans aged 45–84 and the ratio of these (the AnkleBrachial Index) was calculated. During a median follow-up of 13 years, the incidence of symptomatic peripheral artery disease (identified through annual questionnaires, review of hospital records, and notations of peripheral artery disease found in data obtained from the Center for Medicare Services) was compared between persons whose AnkleBrachial Index was ⩽9 and persons with higher AnkleBrachial Index values.ResultsThe incidence of clinical peripheral artery disease wa...

  • Arterial compliance across the spectrum of Ankle-Brachial Index: the Multiethnic Study of Atherosclerosis.
    Atherosclerosis, 2014
    Co-Authors: Scott Lilly, David R. Jacobs, Richard A. Kronmal, David A. Bluemke, Michael H. Criqui, Joao A.c. Lima, Matthew A. Allison, Daniel A. Duprez, Patrick Segers, Julio A. Chirinos
    Abstract:

    Abstract Objective A low Ankle-Brachial Index is associated with cardiovascular disease and reduced arterial compliance. A high Ankle-Brachial Index is also associated with an increased risk of cardiovascular events. We tested the hypothesis that subjects with a high Ankle-Brachial Index demonstrate a lower arterial compliance. In addition, we assessed whether pulse pressure amplification is increased among subjects with a high Ankle-Brachial Index. Methods We studied 6814 adults enrolled in the multiethnic study of atherosclerosis who were, by definition, free of clinical cardiovascular disease at baseline. Differences in total arterial compliance (ratio of stroke volume to pulse pressure), aortic and carotid distensibility (measured with magnetic resonance imaging and duplex ultrasound, respectively) were compared across Ankle-Brachial Index subclasses (≤0.90, 0.91–1.29; ≥1.30) with analyses adjusted for cardiovascular risk factors and subclinical atherosclerosis. Results Peripheral arterial disease was detected in 230 (3.4%) and high ABI in 648 (9.6%) of subjects. Those with high Ankle-Brachial Index demonstrated greater aortic/radial pulse pressure amplification than those with a normal Ankle-Brachial Index. In adjusted models aortic and carotid distensibility as well as total arterial compliance, were lowest among those with Ankle-Brachial Index ≤0.9 ( p Conclusion Lower aortic, carotid and total arterial compliance is not present in subjects free of overt cardiovascular disease and with a high Ankle-Brachial Index. However, increased pulse pressure amplification contributes to a greater Ankle-Brachial Index in the general population and may allow better characterization of individuals with this phenotype.

Naoki Saji - One of the best experts on this subject based on the ideXlab platform.