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Tin Aung – 1st expert on this subject based on the ideXlab platform
automatic Anterior Chamber angle assessment for hd oct imagesIEEE Transactions on Biomedical Engineering, 2011Co-Authors: Jing Tian, Pina Marziliano, Mani Baskaran, Hongtym Wong, Tin AungAbstract:
Angle-closure glaucoma is a major blinding eye disease and could be detected by measuring the Anterior Chamber angle in the human eyes. High-definition OCT (Cirrus HD-OCT) is an emerging noninvasive, high-speed, and high-resolution imaging modality for the Anterior segment of the eye. Here, we propose a novel algorithm which automatically detects a new landmark, Schwalbe’s line, and measures the Anterior Chamber angle in the HD-OCT images. The distortion caused by refraction is corrected by dewarping the HD-OCT images, and three biometric measurements are defined to quantitatively assess the Anterior Chamber angle. The proposed algorithm was tested on 40 HD-OCT images of the eye and provided accurate measurements in about 1 second.
Comparison of Anterior Chamber depth measurements using the IOLMaster, scanning peripheral Anterior Chamber depth analyser, and Anterior segment optical coherence tomographyBRIT J OPHTHALMOL, 2007Co-Authors: Tin AungAbstract:
Aim: To compare Anterior Chamber depth measurements by three non-contact devices – the IOLMaster, scanning peripheral Anterior Chamber depth analyser (SPAC), and Visante Anterior segment optical coherence tomography (AS-OCT)Methods: Prospective, cross sectional study of 497 phakic subjects over 50 years of age attending a community clinic in Singapore. Anterior Chamber depth of the right eye was measured using all three techniques by the same investigator. Depth measurements were made from the corneal epithelium to the Anterior lens surface. The values obtained were compared using Bland – Altman analysis.Results: 232 men and 265 women were examined (mean (SD) age, 63.4 (7.9) years). Mean Anterior Chamber depth was 3.08 (0.36) mm with IOLMaster, 3.10 (0.44) mm with SPAC, and 3.14 (0.34) mm with AS-OCT. A significant difference was present between the Anterior Chamber depth measurements recorded by the three devices (p
Robert N Weinreb – 2nd expert on this subject based on the ideXlab platform
Anterior Chamber angle imaging with optical coherence tomographyEye, 2011Co-Authors: Ks C Leung, Robert N WeinrebAbstract:
The technology of optical coherence tomography (OCT) has evolved rapidly from time-domain to spectral-domain and swept-source OCT over the recent years. OCT has become an important tool for assessment of the Anterior Chamber angle and detection of angle closure. Improvement in image resolution and scan speed of OCT has facilitated a more detailed and comprehensive analysis of the Anterior Chamber angle. It is now possible to examine Schwalbe’s line and Schlemm’s canal along with the scleral spur. High-speed imaging allows evaluation of the angle in 360°. With three-dimensional reconstruction, visualization of the iris profiles and the angle configurations is enhanced. This article summarizes the development and application of OCT for Anterior Chamber angle measurement, detection of angle closure, and investigation of the pathophysiology of primary angle closure.
Mingguang He – 3rd expert on this subject based on the ideXlab platform
Anterior Chamber angle assessment techniquesSurvey of Ophthalmology, 2008Co-Authors: David S Friedman, Mingguang HeAbstract:
Angle-closure glaucoma is a leading cause of irreversible blindness. Diagnosis and treatment are intricately related to angle assessment techniques. This article reviews the literature on angle assessment and provides recommendations about optimal techniques based on the published evidence. Specifically, we review gonioscopy, ultrasound biomicroscopy, and Anterior segment optical coherence tomography, all of which can be used to assess the Anterior Chamber angle directly. In addition, we discuss surrogate approaches to measuring the angle configuration, including limbal Anterior Chamber depth measurement, scanning peripheral Anterior Chamber depth measurement, and Scheimpflug photography.