The Experts below are selected from a list of 282 Experts worldwide ranked by ideXlab platform
B. De Bruyne - One of the best experts on this subject based on the ideXlab platform.
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Dynamic left ventricular outflow tract obstruction after Anterior Myocardial Infarction
European heart journal, 1995Co-Authors: J. Bartunek, M. Vanderheyden, B. De BruyneAbstract:This study describes a dynamic left ventricular outflow tract gradient complicating an acute Anterior Myocardial Infarction in two patients. In both cases, hyperdynamic contraction of the non-infarcted segments were noted in addition to large antero-apical a- or dyskinesia. Both patients had evidence of mitral annular calcifications, and the occurrence of dynamic outflow tract obstruction preceded sudden death. Early recognition of the underlying pathophysiological mechanism might have major therapeutic implications and could decrease the risk of Myocardial rupture.
Haşim Mutlu - One of the best experts on this subject based on the ideXlab platform.
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Plasma homocysteine level and left ventricular thrombus formation in acute Anterior Myocardial Infarction patients following thrombolytic therapy with t-PA.
Thrombosis research, 2009Co-Authors: Ahmet L. Orhan, Ertugrul Okuyan, Barış Ökçün, Zekeriya Nurkalem, Nurten Sayar, Özer Soylu, Nevzat Uslu, Ahmet Yildiz, Mehmet Eren, Haşim MutluAbstract:Abstract Aims The aim of this study was to evaluate the relationship between homocysteine levels and the development of left ventricular thrombus in acute Anterior Myocardial Infarction patients directed to thrombolytic therapy. Methods and Results Seventy-nine patients presenting with ST elevated acute Anterior Myocardial Infarction and treated with thrombolytic agent, t-PA, were included in the study. Two-dimensional echocardiography was used to divide patients into 2 groups according to the presence (n=14) or absence (n=65) of thrombus in the left ventricle following Myocardial Infarction. The levels of fasting plasma total homocysteine, total cholesterol, triglycerides, HDL-cholesterol, LDL-cholesterol, vitamin B12 and folic acid were assessed. There were no significant differences between two groups in terms of age, gender, hyperlipidemia and smoking. History of diabetes mellitus (28.57% versus 6.15%, p=0.04), peak creatine phosphokinase levels (4153.54±1228.41 U/L versus 2456.92±1421.36 U/L, p Conclusion Our results suggest that; diabetes mellitus, higher wall motion score index and hyperhomocysteinemia independently increases the risk for the development of left ventricular thrombus formation in patients with acute Anterior Myocardial Infarction following thrombolytic therapy.
J. Bartunek - One of the best experts on this subject based on the ideXlab platform.
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Dynamic left ventricular outflow tract obstruction after Anterior Myocardial Infarction
European heart journal, 1995Co-Authors: J. Bartunek, M. Vanderheyden, B. De BruyneAbstract:This study describes a dynamic left ventricular outflow tract gradient complicating an acute Anterior Myocardial Infarction in two patients. In both cases, hyperdynamic contraction of the non-infarcted segments were noted in addition to large antero-apical a- or dyskinesia. Both patients had evidence of mitral annular calcifications, and the occurrence of dynamic outflow tract obstruction preceded sudden death. Early recognition of the underlying pathophysiological mechanism might have major therapeutic implications and could decrease the risk of Myocardial rupture.
Ahmet L. Orhan - One of the best experts on this subject based on the ideXlab platform.
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Plasma homocysteine level and left ventricular thrombus formation in acute Anterior Myocardial Infarction patients following thrombolytic therapy with t-PA.
Thrombosis research, 2009Co-Authors: Ahmet L. Orhan, Ertugrul Okuyan, Barış Ökçün, Zekeriya Nurkalem, Nurten Sayar, Özer Soylu, Nevzat Uslu, Ahmet Yildiz, Mehmet Eren, Haşim MutluAbstract:Abstract Aims The aim of this study was to evaluate the relationship between homocysteine levels and the development of left ventricular thrombus in acute Anterior Myocardial Infarction patients directed to thrombolytic therapy. Methods and Results Seventy-nine patients presenting with ST elevated acute Anterior Myocardial Infarction and treated with thrombolytic agent, t-PA, were included in the study. Two-dimensional echocardiography was used to divide patients into 2 groups according to the presence (n=14) or absence (n=65) of thrombus in the left ventricle following Myocardial Infarction. The levels of fasting plasma total homocysteine, total cholesterol, triglycerides, HDL-cholesterol, LDL-cholesterol, vitamin B12 and folic acid were assessed. There were no significant differences between two groups in terms of age, gender, hyperlipidemia and smoking. History of diabetes mellitus (28.57% versus 6.15%, p=0.04), peak creatine phosphokinase levels (4153.54±1228.41 U/L versus 2456.92±1421.36 U/L, p Conclusion Our results suggest that; diabetes mellitus, higher wall motion score index and hyperhomocysteinemia independently increases the risk for the development of left ventricular thrombus formation in patients with acute Anterior Myocardial Infarction following thrombolytic therapy.
Shin-ichi Momomura - One of the best experts on this subject based on the ideXlab platform.
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Contrast echocardiography for the diagnosis of left ventricular thrombus in Anterior Myocardial Infarction.
Heart and vessels, 2013Co-Authors: Hiroshi Wada, Takanori Yasu, Kenichi Sakakura, Yuki Hayakawa, Takeshi Ishida, Nobuhiko Kobayashi, Norifumi Kubo, Junya Ako, Shin-ichi MomomuraAbstract:Although detecting left ventricular thrombus in Anterior Myocardial Infarction is important for the prevention of embolic events, imaging of apical thrombus is often difficult using conventional echocardiography. We examined whether contrast echocardiography improves sensitivity and specificity in detecting thrombus in the left ventricle in comparison with conventional echocardiography alone in patients with Anterior Myocardial Infarction. Participants in this single-center prospective study comprised 392 patients with Anterior Myocardial Infarction admitted between 2000 and 2006. After conventional echocardiography, all patients underwent contrast echocardiography (left ventricular opacification and Myocardial contrast echocardiography) during intravenous drip infusion of contrast media at rest. Left ventricular thrombus was diagnosed based on left ventriculography or multidetector-row computed tomography (MDCT). Mural left ventricular thrombus was confirmed by left ventriculography and/or MDCT in 32 of 393 patients (8 %). Sensitivity and specificity of conventional echocardiography alone were 88 % and 96 %, respectively, compared with 100 % each with contrast echocardiography. Among the 32 patients with left ventricular thrombus, 25 patients (78 %) showed no perfusion in the Anterior wall on Myocardial contrast echocardiography, even with a four-beat interval. In conclusion, contrast echocardiography offers a clinically feasible and useful method for noninvasively evaluating left ventricular thrombus in Anterior Myocardial Infarction.