The Experts below are selected from a list of 135 Experts worldwide ranked by ideXlab platform

Jong Kwan Park - One of the best experts on this subject based on the ideXlab platform.

Steven A Kaplan - One of the best experts on this subject based on the ideXlab platform.

  • re twelve week prospective open label randomized trial on the effects of an anticholinergic Agent or Antidiuretic Agent as add on therapy to an alpha blocker for lower urinary tract symptoms
    The Journal of Urology, 2015
    Co-Authors: Steven A Kaplan
    Abstract:

    for this article http://dx.doi.org/10.1016/j.juro.2015.08.038 available at http://jurology.com/ Editorial Comment: Precision medicine is a glossy term that is often used as a goal in delivery of optimal outcomes. Notwithstanding costs and access, this concept is a more achievable goal than in the past. For example in the arena of lower urinary tract symptoms in men the ability to hone in on types of symptoms, ie storage vs voiding, and prostate size can help us to prescribe the most appropriate therapy. With a new cadre of available Agents that can address nocturia, overactive bladder symptoms and sexual dysfunction we can more precisely diagnose and treat men with lower urinary tract symptoms. This study tests that hypothesis by using either desmopressin or an anticholinergic Agent as an add-on to an alpha blocker. The authors found that the addition of desmopressin helped decrease the number of nocturnal episodes, nocturnal urine volume and nocturnal index in men with nocturnal polyuria. Similarly the nocturnal bladder capacity index and urgency episodes decreased in the anticholinergic add-on group. Nocturia is multifactorial and not just related to benign prostatic hyperplasia. Yet we often use classic benign prostatic hyperplasia Agents such as alpha blockers in an attempt to treat men with nocturia. Studies such as this highlight the need to hone in on what is causing nocturia in an individual, including concomitant disorders such as diabetes, sleep apnea, polydipsia, reduced bladder capacity and polyuria. The take home message is that, as experts in voiding function in men (and women!), we should tailor our therapies to the specific complaint of the patient and take into account prostate size, types of symptoms and causative etiology of nocturia to deliver better health outcomes and more durable and sustainable results. Steven A. Kaplan, MD Suggested Reading Lose G, Mattiasson A, Walter S et al: Clinical experiences with desmopressin for long-term treatment of nocturia. J Urol 2004; 172: 1021.

Yu Seob Shin - One of the best experts on this subject based on the ideXlab platform.

Li Tao Zhang - One of the best experts on this subject based on the ideXlab platform.

Chen Zhao - One of the best experts on this subject based on the ideXlab platform.