The Experts below are selected from a list of 315 Experts worldwide ranked by ideXlab platform

A Haverich - One of the best experts on this subject based on the ideXlab platform.

  • Impact of preoperative Aortic Root diameter on long-term Aortic valve function after valve sparing Aortic Root reimplantation.
    Circulation, 2003
    Co-Authors: R G Leyh, K Kallenbach, M Karck, C Hagl, S Fischer, A Haverich
    Abstract:

    Valve sparing Aortic Root reimplantation technique in patients with Aortic Root aneurysm have shown excellent mid-term results. In conjunction with the diameter of the Aortic Root the mechanical leaflet stress increase, which might have an impact on long-term Aortic valve function after valve sparing Aortic Root reimplantation. From July 1993 to October 2001, 168 patients with Aortic Root aneurysm underwent valve sparing Aortic Root reimplantation. Patients with type A Aortic dissection were excluded. Thus, 123 patients were analyzed. We identified 47 patients with an preoperative Aortic Root diameter exceeding 60 mm (group A), 58 patients with an diameter between 50 and 60 mm (group B), and 18 patients with a diameter less than 50 mm (group C). The groups were compared regarding mortality, long-term survival, freedom from reoperation, freedom from severe and moderate Aortic valve insufficiency (AI), and postoperative morbidity. Mean follow-up (group A 43+/-26 months, group B 40+/-25 months, group C 23+/-19 months; group C versus group A, P=0.005; group C versus group B, P=0.011) was shorter in group C. Perioperative mortality (group A 2.2%, group B 1.9%, group C 5.2%; P=ns) was comparable between the groups with each one patient. The 3-year survival for group A was 98+/-2%, for group B 96+/-3%, and for group C 100+/-0% (P=ns). Freedom from reoperation for group A was 98+/-2%, for group B 96+/-3%, and for group C 88+/-8% (P=ns). Four patients developed severe or moderate AI, thus freedom from severe and moderate AI for group A was 100+/-0%, for group B 88+/-8%, and for group C 94+/-5% (P=ns). During follow-up no thromboembolic or bleeding events were noticed. Our data show that the preoperative diameter of the Aortic Root has no impact on the longevity of the repair. Thus, the reimplantation technique can be recommended for all patients presenting with an Aortic Root aneurysm and normal leaflets regardless of the Aortic Root diameter.

  • Impact of Preoperative Aortic Root Diameter on Long-Term Aortic Valve Function After Valve Sparing Aortic Root Reimplantation
    Circulation, 2003
    Co-Authors: R G Leyh, K Kallenbach, M Karck, C Hagl, S Fischer, A Haverich
    Abstract:

    Background— Valve sparing Aortic Root reimplantation technique in patients with Aortic Root aneurysm have shown excellent mid-term results. In conjunction with the diameter of the Aortic Root the mechanical leaflet stress increase, which might have an impact on long-term Aortic valve function after valve sparing Aortic Root reimplantation. Methods and Results— From July 1993 to October 2001, 168 patients with Aortic Root aneurysm underwent valve sparing Aortic Root reimplantation. Patients with type A Aortic dissection were excluded. Thus, 123 patients were analyzed. We identified 47 patients with an preoperative Aortic Root diameter exceeding 60 mm (group A), 58 patients with an diameter between 50 and 60 mm (group B), and 18 patients with a diameter less than 50 mm (group C). The groups were compared regarding mortality, long-term survival, freedom from reoperation, freedom from severe and moderate Aortic valve insufficiency (AI), and postoperative morbidity. Mean follow-up (group A 43±26 months, group B 40±25 months, group C 23±19 months; group C versus group A, P =0.005; group C versus group B, P =0.011) was shorter in group C. Perioperative mortality (group A 2.2%, group B 1.9%, group C 5.2%; P =ns) was comparable between the groups with each one patient. The 3-year survival for group A was 98±2%, for group B 96±3%, and for group C 100±0% ( P =ns). Freedom from reoperation for group A was 98±2%, for group B 96±3%, and for group C 88±8% ( P =ns). Four patients developed severe or moderate AI, thus freedom from severe and moderate AI for group A was 100±0%, for group B 88±8%, and for group C 94±5% ( P =ns). During follow-up no thromboembolic or bleeding events were noticed. Conclusions— Our data show that the preoperative diameter of the Aortic Root has no impact on the longevity of the repair. Thus, the reimplantation technique can be recommended for all patients presenting with an Aortic Root aneurysm and normal leaflets regardless of the Aortic Root diameter.

Siavosh Khonsari - One of the best experts on this subject based on the ideXlab platform.

  • stentless porcine Aortic Root valve of choice for the elderly patient with small Aortic Root
    The Journal of Thoracic and Cardiovascular Surgery, 1995
    Co-Authors: Colleen F Sintek, Alden D Fletcher, Siavosh Khonsari
    Abstract:

    Abstract The Medtronic Freestyle bioprosthesis is a stentless porcine Aortic Root cross-linked in dilute glutaraldehyde solution with stress-free fixation for the valve leaflets. It has been treated by a process in which amino oleic acid is used to reduce the potential for calcification. As a complete Aortic Root, it has the same versatility as the Aortic homograft but has the advantage that it is readily available in all sizes to the implanting surgeon. Between January 1993 and May 1994, we implanted 64 Freestyle bioprostheses as Aortic valve replacements using a freehand technique; 5 size 19 mm, 15 size 21 mm, 16 size 23 mm, 13 size 25 mm, and 15 size 27 mm valves were used. There were 35 men and the mean age was 75.7 years (64 to 84 years). The operative mortality was 3.1% (2/64). Echocardiograms at the time of discharge revealed mean Aortic valve gradients ranging from 18.2 mm Hg for 19 mm to 10.3 mm Hg for 27 mm valves. Effective orifice areas ranged from 1.0 cm 2 for 19 mm to 2.0 cm 2 for 27 mm valves. No patient had more than trace Aortic insufficiency. Our early experience with this new stentless bioprosthesis shows it to have excellent hemodynamics especially in the smaller valve sizes. Using this valve in patients who have a small Aortic Root and require a tissue valve avoids the need for Aortic Root enlargement procedures. (J THORAC CARDIOVASC SURG 1995;109:871-6)

  • Stentless porcine Aortic Root: Valve of choice for the elderly patient with small Aortic Root?
    The Journal of thoracic and cardiovascular surgery, 1995
    Co-Authors: Colleen F Sintek, Alden D Fletcher, Siavosh Khonsari
    Abstract:

    Abstract The Medtronic Freestyle bioprosthesis is a stentless porcine Aortic Root cross-linked in dilute glutaraldehyde solution with stress-free fixation for the valve leaflets. It has been treated by a process in which amino oleic acid is used to reduce the potential for calcification. As a complete Aortic Root, it has the same versatility as the Aortic homograft but has the advantage that it is readily available in all sizes to the implanting surgeon. Between January 1993 and May 1994, we implanted 64 Freestyle bioprostheses as Aortic valve replacements using a freehand technique; 5 size 19 mm, 15 size 21 mm, 16 size 23 mm, 13 size 25 mm, and 15 size 27 mm valves were used. There were 35 men and the mean age was 75.7 years (64 to 84 years). The operative mortality was 3.1% (2/64). Echocardiograms at the time of discharge revealed mean Aortic valve gradients ranging from 18.2 mm Hg for 19 mm to 10.3 mm Hg for 27 mm valves. Effective orifice areas ranged from 1.0 cm 2 for 19 mm to 2.0 cm 2 for 27 mm valves. No patient had more than trace Aortic insufficiency. Our early experience with this new stentless bioprosthesis shows it to have excellent hemodynamics especially in the smaller valve sizes. Using this valve in patients who have a small Aortic Root and require a tissue valve avoids the need for Aortic Root enlargement procedures. (J THORAC CARDIOVASC SURG 1995;109:871-6)

R G Leyh - One of the best experts on this subject based on the ideXlab platform.

  • Impact of preoperative Aortic Root diameter on long-term Aortic valve function after valve sparing Aortic Root reimplantation.
    Circulation, 2003
    Co-Authors: R G Leyh, K Kallenbach, M Karck, C Hagl, S Fischer, A Haverich
    Abstract:

    Valve sparing Aortic Root reimplantation technique in patients with Aortic Root aneurysm have shown excellent mid-term results. In conjunction with the diameter of the Aortic Root the mechanical leaflet stress increase, which might have an impact on long-term Aortic valve function after valve sparing Aortic Root reimplantation. From July 1993 to October 2001, 168 patients with Aortic Root aneurysm underwent valve sparing Aortic Root reimplantation. Patients with type A Aortic dissection were excluded. Thus, 123 patients were analyzed. We identified 47 patients with an preoperative Aortic Root diameter exceeding 60 mm (group A), 58 patients with an diameter between 50 and 60 mm (group B), and 18 patients with a diameter less than 50 mm (group C). The groups were compared regarding mortality, long-term survival, freedom from reoperation, freedom from severe and moderate Aortic valve insufficiency (AI), and postoperative morbidity. Mean follow-up (group A 43+/-26 months, group B 40+/-25 months, group C 23+/-19 months; group C versus group A, P=0.005; group C versus group B, P=0.011) was shorter in group C. Perioperative mortality (group A 2.2%, group B 1.9%, group C 5.2%; P=ns) was comparable between the groups with each one patient. The 3-year survival for group A was 98+/-2%, for group B 96+/-3%, and for group C 100+/-0% (P=ns). Freedom from reoperation for group A was 98+/-2%, for group B 96+/-3%, and for group C 88+/-8% (P=ns). Four patients developed severe or moderate AI, thus freedom from severe and moderate AI for group A was 100+/-0%, for group B 88+/-8%, and for group C 94+/-5% (P=ns). During follow-up no thromboembolic or bleeding events were noticed. Our data show that the preoperative diameter of the Aortic Root has no impact on the longevity of the repair. Thus, the reimplantation technique can be recommended for all patients presenting with an Aortic Root aneurysm and normal leaflets regardless of the Aortic Root diameter.

  • Impact of Preoperative Aortic Root Diameter on Long-Term Aortic Valve Function After Valve Sparing Aortic Root Reimplantation
    Circulation, 2003
    Co-Authors: R G Leyh, K Kallenbach, M Karck, C Hagl, S Fischer, A Haverich
    Abstract:

    Background— Valve sparing Aortic Root reimplantation technique in patients with Aortic Root aneurysm have shown excellent mid-term results. In conjunction with the diameter of the Aortic Root the mechanical leaflet stress increase, which might have an impact on long-term Aortic valve function after valve sparing Aortic Root reimplantation. Methods and Results— From July 1993 to October 2001, 168 patients with Aortic Root aneurysm underwent valve sparing Aortic Root reimplantation. Patients with type A Aortic dissection were excluded. Thus, 123 patients were analyzed. We identified 47 patients with an preoperative Aortic Root diameter exceeding 60 mm (group A), 58 patients with an diameter between 50 and 60 mm (group B), and 18 patients with a diameter less than 50 mm (group C). The groups were compared regarding mortality, long-term survival, freedom from reoperation, freedom from severe and moderate Aortic valve insufficiency (AI), and postoperative morbidity. Mean follow-up (group A 43±26 months, group B 40±25 months, group C 23±19 months; group C versus group A, P =0.005; group C versus group B, P =0.011) was shorter in group C. Perioperative mortality (group A 2.2%, group B 1.9%, group C 5.2%; P =ns) was comparable between the groups with each one patient. The 3-year survival for group A was 98±2%, for group B 96±3%, and for group C 100±0% ( P =ns). Freedom from reoperation for group A was 98±2%, for group B 96±3%, and for group C 88±8% ( P =ns). Four patients developed severe or moderate AI, thus freedom from severe and moderate AI for group A was 100±0%, for group B 88±8%, and for group C 94±5% ( P =ns). During follow-up no thromboembolic or bleeding events were noticed. Conclusions— Our data show that the preoperative diameter of the Aortic Root has no impact on the longevity of the repair. Thus, the reimplantation technique can be recommended for all patients presenting with an Aortic Root aneurysm and normal leaflets regardless of the Aortic Root diameter.

Colleen F Sintek - One of the best experts on this subject based on the ideXlab platform.

  • stentless porcine Aortic Root valve of choice for the elderly patient with small Aortic Root
    The Journal of Thoracic and Cardiovascular Surgery, 1995
    Co-Authors: Colleen F Sintek, Alden D Fletcher, Siavosh Khonsari
    Abstract:

    Abstract The Medtronic Freestyle bioprosthesis is a stentless porcine Aortic Root cross-linked in dilute glutaraldehyde solution with stress-free fixation for the valve leaflets. It has been treated by a process in which amino oleic acid is used to reduce the potential for calcification. As a complete Aortic Root, it has the same versatility as the Aortic homograft but has the advantage that it is readily available in all sizes to the implanting surgeon. Between January 1993 and May 1994, we implanted 64 Freestyle bioprostheses as Aortic valve replacements using a freehand technique; 5 size 19 mm, 15 size 21 mm, 16 size 23 mm, 13 size 25 mm, and 15 size 27 mm valves were used. There were 35 men and the mean age was 75.7 years (64 to 84 years). The operative mortality was 3.1% (2/64). Echocardiograms at the time of discharge revealed mean Aortic valve gradients ranging from 18.2 mm Hg for 19 mm to 10.3 mm Hg for 27 mm valves. Effective orifice areas ranged from 1.0 cm 2 for 19 mm to 2.0 cm 2 for 27 mm valves. No patient had more than trace Aortic insufficiency. Our early experience with this new stentless bioprosthesis shows it to have excellent hemodynamics especially in the smaller valve sizes. Using this valve in patients who have a small Aortic Root and require a tissue valve avoids the need for Aortic Root enlargement procedures. (J THORAC CARDIOVASC SURG 1995;109:871-6)

  • Stentless porcine Aortic Root: Valve of choice for the elderly patient with small Aortic Root?
    The Journal of thoracic and cardiovascular surgery, 1995
    Co-Authors: Colleen F Sintek, Alden D Fletcher, Siavosh Khonsari
    Abstract:

    Abstract The Medtronic Freestyle bioprosthesis is a stentless porcine Aortic Root cross-linked in dilute glutaraldehyde solution with stress-free fixation for the valve leaflets. It has been treated by a process in which amino oleic acid is used to reduce the potential for calcification. As a complete Aortic Root, it has the same versatility as the Aortic homograft but has the advantage that it is readily available in all sizes to the implanting surgeon. Between January 1993 and May 1994, we implanted 64 Freestyle bioprostheses as Aortic valve replacements using a freehand technique; 5 size 19 mm, 15 size 21 mm, 16 size 23 mm, 13 size 25 mm, and 15 size 27 mm valves were used. There were 35 men and the mean age was 75.7 years (64 to 84 years). The operative mortality was 3.1% (2/64). Echocardiograms at the time of discharge revealed mean Aortic valve gradients ranging from 18.2 mm Hg for 19 mm to 10.3 mm Hg for 27 mm valves. Effective orifice areas ranged from 1.0 cm 2 for 19 mm to 2.0 cm 2 for 27 mm valves. No patient had more than trace Aortic insufficiency. Our early experience with this new stentless bioprosthesis shows it to have excellent hemodynamics especially in the smaller valve sizes. Using this valve in patients who have a small Aortic Root and require a tissue valve avoids the need for Aortic Root enlargement procedures. (J THORAC CARDIOVASC SURG 1995;109:871-6)

S Fischer - One of the best experts on this subject based on the ideXlab platform.

  • Impact of preoperative Aortic Root diameter on long-term Aortic valve function after valve sparing Aortic Root reimplantation.
    Circulation, 2003
    Co-Authors: R G Leyh, K Kallenbach, M Karck, C Hagl, S Fischer, A Haverich
    Abstract:

    Valve sparing Aortic Root reimplantation technique in patients with Aortic Root aneurysm have shown excellent mid-term results. In conjunction with the diameter of the Aortic Root the mechanical leaflet stress increase, which might have an impact on long-term Aortic valve function after valve sparing Aortic Root reimplantation. From July 1993 to October 2001, 168 patients with Aortic Root aneurysm underwent valve sparing Aortic Root reimplantation. Patients with type A Aortic dissection were excluded. Thus, 123 patients were analyzed. We identified 47 patients with an preoperative Aortic Root diameter exceeding 60 mm (group A), 58 patients with an diameter between 50 and 60 mm (group B), and 18 patients with a diameter less than 50 mm (group C). The groups were compared regarding mortality, long-term survival, freedom from reoperation, freedom from severe and moderate Aortic valve insufficiency (AI), and postoperative morbidity. Mean follow-up (group A 43+/-26 months, group B 40+/-25 months, group C 23+/-19 months; group C versus group A, P=0.005; group C versus group B, P=0.011) was shorter in group C. Perioperative mortality (group A 2.2%, group B 1.9%, group C 5.2%; P=ns) was comparable between the groups with each one patient. The 3-year survival for group A was 98+/-2%, for group B 96+/-3%, and for group C 100+/-0% (P=ns). Freedom from reoperation for group A was 98+/-2%, for group B 96+/-3%, and for group C 88+/-8% (P=ns). Four patients developed severe or moderate AI, thus freedom from severe and moderate AI for group A was 100+/-0%, for group B 88+/-8%, and for group C 94+/-5% (P=ns). During follow-up no thromboembolic or bleeding events were noticed. Our data show that the preoperative diameter of the Aortic Root has no impact on the longevity of the repair. Thus, the reimplantation technique can be recommended for all patients presenting with an Aortic Root aneurysm and normal leaflets regardless of the Aortic Root diameter.

  • Impact of Preoperative Aortic Root Diameter on Long-Term Aortic Valve Function After Valve Sparing Aortic Root Reimplantation
    Circulation, 2003
    Co-Authors: R G Leyh, K Kallenbach, M Karck, C Hagl, S Fischer, A Haverich
    Abstract:

    Background— Valve sparing Aortic Root reimplantation technique in patients with Aortic Root aneurysm have shown excellent mid-term results. In conjunction with the diameter of the Aortic Root the mechanical leaflet stress increase, which might have an impact on long-term Aortic valve function after valve sparing Aortic Root reimplantation. Methods and Results— From July 1993 to October 2001, 168 patients with Aortic Root aneurysm underwent valve sparing Aortic Root reimplantation. Patients with type A Aortic dissection were excluded. Thus, 123 patients were analyzed. We identified 47 patients with an preoperative Aortic Root diameter exceeding 60 mm (group A), 58 patients with an diameter between 50 and 60 mm (group B), and 18 patients with a diameter less than 50 mm (group C). The groups were compared regarding mortality, long-term survival, freedom from reoperation, freedom from severe and moderate Aortic valve insufficiency (AI), and postoperative morbidity. Mean follow-up (group A 43±26 months, group B 40±25 months, group C 23±19 months; group C versus group A, P =0.005; group C versus group B, P =0.011) was shorter in group C. Perioperative mortality (group A 2.2%, group B 1.9%, group C 5.2%; P =ns) was comparable between the groups with each one patient. The 3-year survival for group A was 98±2%, for group B 96±3%, and for group C 100±0% ( P =ns). Freedom from reoperation for group A was 98±2%, for group B 96±3%, and for group C 88±8% ( P =ns). Four patients developed severe or moderate AI, thus freedom from severe and moderate AI for group A was 100±0%, for group B 88±8%, and for group C 94±5% ( P =ns). During follow-up no thromboembolic or bleeding events were noticed. Conclusions— Our data show that the preoperative diameter of the Aortic Root has no impact on the longevity of the repair. Thus, the reimplantation technique can be recommended for all patients presenting with an Aortic Root aneurysm and normal leaflets regardless of the Aortic Root diameter.