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Dick H J Thijssen - One of the best experts on this subject based on the ideXlab platform.
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femoral Artery Blood Flow and microcirculatory perfusion during acute low level functional electrical stimulation in spinal cord injury
American Journal of Physical Medicine & Rehabilitation, 2018Co-Authors: Thomas J Barton, David A Low, Thomas W J Janssen, Maurits Sloots, C A J Smit, Dick H J ThijssenAbstract:Objective – Functional electrical stimulation (FES) may help to reduce the risk of developing macro- and microvascular complications in people with SCI. Low-intensity FES has significant clinical potential since this can be applied continuously throughout the day. This study examines the acute effects of low intensity FES using wearable clothing garment on vascular Blood Flow and oxygen consumption in people with SCI. Design – Cross-sectional observation study Methods – Eight participants with a motor complete SCI received 4x3 minutes of unilateral FES to the gluteal and hamstring muscles. Skin and deep femoral Artery Blood Flow and oxygen consumption were measured at baseline and during each bout of stimulation. Results – Femoral Artery Blood Flow increased by 18.1% with the application of FES (P=0.02). Moreover, femoral Artery Blood Flow increased further during each subsequent block of FES (P=0.004). Skin perfusion did not change during an individual block of stimulation (P=0.66). Skin perfusion progressively increased with each subsequent bout (P 0.05). Conclusion – Low-intensity FES acutely increased Blood Flow during stimulation, with a progressive increase across subsequent FES bouts. These observations suggest continuous, low-intensity FES may represent a practical and effective strategy to improve perfusion and reduce the risk of vascular complications.
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brachial Artery adaptation to lower limb exercise training role of shear stress
Journal of Applied Physiology, 2012Co-Authors: Gurpreet K Birk, Dick H J Thijssen, Ellen A Dawson, Nigel T Cable, Ceri Atkinson, Andrew Haynes, Daniel J GreenAbstract:Lower limb exercise increases upper limb conduit Artery Blood Flow and shear stress, and leg exercise training can enhance upper limb vascular function. We therefore examined the contribution of sh...
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brachial Artery Blood Flow responses to different modalities of lower limb exercise
Medicine and Science in Sports and Exercise, 2009Co-Authors: Dick H J Thijssen, Ellen A Dawson, Mark A Black, Maria T E Hopman, Nigel T Cable, Daniel J GreenAbstract:THIJSSEN, D. H. J., E. A. DAWSON, M. A. BLACK, M. T. E. HOPMAN, N. T. CABLE, and D. J. GREEN. Brachial Artery Blood Flow Responses to Different Modalities of Lower Limb Exercise. Med. Sci. Sports Exerc., Vol. 41, No. 5, pp. 1072-1079, 2009. Introduction/Purpose: Cycling is associated with a reproducible systolic anterograde and diastolic retrograde Flow pattern in the brachial Artery (BA) of the inactive upper limb, which results in endothelial nitric oxide (NO) release. The purpose of this study was to examine the impact of different types and intensities of lower limb exercise on the BA Flow pattern. Methods: We examined BA Blood Flow and shear rate patterns during cycling, leg kicking, and walking exercise in 12 young subjects (24 T 3 yr). BA diameter, Blood Flow, and shear rate were assessed at baseline (1 min) and at three incremental intensity levels of cycling (60, 80, and 120 W), bilateral leg kicking (5, 7.5, and 10 kg), and walking (3, 4, and 5 kmIh j1 ), performed for 3 min each. Edge detection and wall tracking of high- resolution B-mode arterial ultrasound images, combined with synchronized Doppler waveform envelope analysis, were used to calculate conduit Artery diameter and anterograde/retrograde Blood Flow and shear rate continuously across the cardiac cycle. Results: BA mean Blood Flow and shear rate increased significantly throughout each exercise protocol (P G 0.001), and BA anterograde Blood Flow and shear rate showed comparable increases throughout each protocol (P G 0.001). Retrograde Blood Flow and shear rate, however, demonstrated a significant increase during cycling and walking (P G 0.001) but not during leg kicking. Conclusion: Rhythmic lower limb exercise (cycling and walking) results in an increase in BA systolic anterograde Blood Flow and shear rate, directly followed by a large retrograde Flow and shear rate. This typical pattern, previously linked with endothelial NO release, is not present during a different
Daniel J Green - One of the best experts on this subject based on the ideXlab platform.
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brachial Artery adaptation to lower limb exercise training role of shear stress
Journal of Applied Physiology, 2012Co-Authors: Gurpreet K Birk, Dick H J Thijssen, Ellen A Dawson, Nigel T Cable, Ceri Atkinson, Andrew Haynes, Daniel J GreenAbstract:Lower limb exercise increases upper limb conduit Artery Blood Flow and shear stress, and leg exercise training can enhance upper limb vascular function. We therefore examined the contribution of sh...
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brachial Artery Blood Flow responses to different modalities of lower limb exercise
Medicine and Science in Sports and Exercise, 2009Co-Authors: Dick H J Thijssen, Ellen A Dawson, Mark A Black, Maria T E Hopman, Nigel T Cable, Daniel J GreenAbstract:THIJSSEN, D. H. J., E. A. DAWSON, M. A. BLACK, M. T. E. HOPMAN, N. T. CABLE, and D. J. GREEN. Brachial Artery Blood Flow Responses to Different Modalities of Lower Limb Exercise. Med. Sci. Sports Exerc., Vol. 41, No. 5, pp. 1072-1079, 2009. Introduction/Purpose: Cycling is associated with a reproducible systolic anterograde and diastolic retrograde Flow pattern in the brachial Artery (BA) of the inactive upper limb, which results in endothelial nitric oxide (NO) release. The purpose of this study was to examine the impact of different types and intensities of lower limb exercise on the BA Flow pattern. Methods: We examined BA Blood Flow and shear rate patterns during cycling, leg kicking, and walking exercise in 12 young subjects (24 T 3 yr). BA diameter, Blood Flow, and shear rate were assessed at baseline (1 min) and at three incremental intensity levels of cycling (60, 80, and 120 W), bilateral leg kicking (5, 7.5, and 10 kg), and walking (3, 4, and 5 kmIh j1 ), performed for 3 min each. Edge detection and wall tracking of high- resolution B-mode arterial ultrasound images, combined with synchronized Doppler waveform envelope analysis, were used to calculate conduit Artery diameter and anterograde/retrograde Blood Flow and shear rate continuously across the cardiac cycle. Results: BA mean Blood Flow and shear rate increased significantly throughout each exercise protocol (P G 0.001), and BA anterograde Blood Flow and shear rate showed comparable increases throughout each protocol (P G 0.001). Retrograde Blood Flow and shear rate, however, demonstrated a significant increase during cycling and walking (P G 0.001) but not during leg kicking. Conclusion: Rhythmic lower limb exercise (cycling and walking) results in an increase in BA systolic anterograde Blood Flow and shear rate, directly followed by a large retrograde Flow and shear rate. This typical pattern, previously linked with endothelial NO release, is not present during a different
Abdel Wahab S Khafagy - One of the best experts on this subject based on the ideXlab platform.
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correlation between penile cavernosal Artery Blood Flow and retinal vascular findings in arteriogenic erectile dysfunction
Clinical Ophthalmology, 2010Co-Authors: Ahmed M Emarah, Shawky M Elhaggar, Ihab A Osman, Abdel Wahab S KhafagyAbstract:Objectives: Arteriogenic erectile dysfunction (ED) is a target organ disease of atherosclerosis, and therefore might be a predictor of systemic atherosclerosis. Being systemic, it might be possible to evaluate the extent of atherosclerosis from retinal vascular findings. We investigated the possible correlation between penile cavernosal Artery Blood Flow and retinal vascular findings in patients with arteriogenic ED.
Gary C Brown - One of the best experts on this subject based on the ideXlab platform.
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successful scleral buckling procedures decrease central retinal Artery Blood Flow velocity
Ophthalmology, 1993Co-Authors: Carl D Regillo, Robert C Sergott, Gary C BrownAbstract:Background: Limited data suggest that scleral buckling procedures may decrease posterior segment Blood Flow. How this may affect functional outcome remains unknown. Methods: In a prospective, controlled study, color Doppler imaging was used to measure Blood Flow velocities in the central retinal and ophthalmic arteries of both eyes in patients with unilateral rhegmatogenous retinal detachments before and after primary scleral buckle repair. Encircling elements were used in all patients. Fellow eyes served as controls. Results: Data from six consecutive patients did not show significant preoperative circulatory abnormalities in either Artery compared with the controls. There was a statistically significant reduction in mean central retinal Artery Blood Flow velocities of up to 53% in the immediate postoperative period. Ophthalmic Artery Blood Flow velocities, however, did not significantly change after the procedure. Successful retinal reattachment with the expected visual improvement was achieved in all patients with this primary surgery. Conclusions: Scleral buckling procedures with encircling elements decrease Blood Flow velocities in the central retinal Artery but leave the ophthalmic Artery unaffected. Good anatomic and functional results still can be achieved despite these hemodynamic changes.
Ahmed M Emarah - One of the best experts on this subject based on the ideXlab platform.
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correlation between penile cavernosal Artery Blood Flow and retinal vascular findings in arteriogenic erectile dysfunction
Clinical Ophthalmology, 2010Co-Authors: Ahmed M Emarah, Shawky M Elhaggar, Ihab A Osman, Abdel Wahab S KhafagyAbstract:Objectives: Arteriogenic erectile dysfunction (ED) is a target organ disease of atherosclerosis, and therefore might be a predictor of systemic atherosclerosis. Being systemic, it might be possible to evaluate the extent of atherosclerosis from retinal vascular findings. We investigated the possible correlation between penile cavernosal Artery Blood Flow and retinal vascular findings in patients with arteriogenic ED.
