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Sudhakar Pipavath – One of the best experts on this subject based on the ideXlab platform.

  • imaging of occupational lung disease
    Radiologic Clinics of North America, 2016
    Co-Authors: Jay Champlin, Rachael Edwards, Sudhakar Pipavath

    Abstract:

    Occupational lung Diseases span a variety of pulmonary disorders caused by inhalation of dusts or chemical antigens in a vocational setting. Included in these are the classic mineral pneumoconioses of silicosis, coal worker’s pneumoconiosis, and Asbestos-Related Diseases as well as many immune-mediated and airway-centric Diseases, and new and emerging disorders. Although some of these have characteristic imaging appearances, a multidisciplinary approach with focus on occupational exposure history is essential to proper diagnosis.

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Maria Camila Rodriguez – One of the best experts on this subject based on the ideXlab platform.

  • an asbestos contaminated town in the vicinity of an asbestos cement facility the case study of sibate colombia
    Environmental Research, 2019
    Co-Authors: Juan Pablo Ramosbonilla, Pietro Comba, Roberto Pasetto, Maria Fernanda Celygarcia, Margarita Giraldo, Benedetto Terracini, Daniela Marsili, Valeria Ascoli, Benjamin Lysaniuk, Maria Camila Rodriguez

    Abstract:

    Abstract Introduction The asbestos industry began operations in Colombia in 1942, with an asbestos-cement facility located in the municipality of Sibate. In recent years residents from Sibate have been complaining about what they consider is an unusually large number of people diagnosed with Asbestos-Related Diseases in the town. A study to analyze the situation of Sibate started in 2015, to verify if the number of asbestos related Diseases being diagnosed were higher than expected, and to identify potential asbestos exposure sources in the town. Methods A health and socioeconomic survey was implemented door-to-door to identify potential Asbestos-Related Diseases. Several self-reported mesothelioma cases were identified, and for confirmation purposes, copies of the medical record with the histopathology report were obtained. A panel of six physicians analyzed the medical records. Information of validated cases was used to estimate the male and female age-adjusted incidence rate for Sibate. Based on reports of the existence of potential asbestos-contaminated landfills, topographic maps, a digital elevation model, and current satellite images were crossed using a geographic information system to identify potential landfilled areas, and soils samples were collected in some of these areas. Results A total of 355 surveys were completed, and 29 self-reported mesothelioma cases were identified. Twenty-five of these cases have been persons who had lived at some moment of their lives in Sibate. It was possible to obtain copies of the medical diagnosis for 17 cases. Of these, the panel of physicians classified 15 cases as certain pleural mesothelioma, one as probable, and one as not mesothelioma. Based on this information, the estimated age-adjusted incidence rate of mesothelioma in Sibate was 3.1 × 105 persons-year for males and 1.6 × 105 persons-year for females. These rates are high in comparison to those reported in other cities, regions, and countries of the world. Using geographic information systems, landfilled zones in the urban area of Sibate were identified, on top of which a school and different sports facilities were built. The analysis of four soil samples collected in landfilled zones, confirmed the existence of an underground layer of friable and non-friable asbestos. Conclusion The collected evidence suggests the presence of a malignant pleural mesothelioma cluster in Sibate.

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Jean-claude Pairon – One of the best experts on this subject based on the ideXlab platform.

  • Anxious and depressive symptoms in the French Asbestos-Related Diseases Cohort: risk factors and self-perception of risk
    The European Journal of Public Health, 2016
    Co-Authors: Ibrahim Mounchetrou Njoya, Jean-claude Pairon, Christophe Paris, Jérôme Dinet, Amandine Luc, Joëlle Lighezzolo-alnot, Isabelle Thaon

    Abstract:

    Background: Asbestos is known to be an independent risk factor for lung and pleural cancers. However, to date, little attention has been paid to the psychological effects of asbestos exposure among exposed subjects. The objectives of this study were to estimate the prevalence of anxious and depressive symptoms among >2000 French participants of the Asbestos-Related Diseases Cohort (ARDCO), 6 years after their inclusion, to identify the risk factors associated with those anxious and depressive symptoms and to evaluate the impact of the asbestos-risk perception. Methods: The ARDCO was constituted in four regions of France between October 2003 and December 2005, by including former asbestos workers. Between 2011 and 2012, participants of the ARDCO program were invited to undergo another chest CT scan 6 years after the previous scan. Participants were asked to complete questionnaires including asbestos exposure assessment, Hospital Anxiety and Depression Scale (HADS), asbestos-risk perception and self-perception of Asbestos-Related Diseases. Results: Among the 2225 participants, 2210 fully completed questionnaires were collected and analyzed. The prevalence of symptoms of probable anxiety and probable depression was 19.7% and 9.9%, respectively. The risk of anxious and depressive symptoms was independently associated with self-perception of the intensity of asbestos exposure, asbestos-risk perception and self-perception of Asbestos-Related Diseases. Conclusion: The results obtained in this large study confirm that previously asbestos-exposed subjects are likely to develop anxious and depressive symptoms. Finally, implications related to the prevention of anxiety and depression among asbestos-exposed workers is discussed.

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  • Asbestos-Related Diseases in automobile mechanics.
    Annals of Occupational Hygiene, 2012
    Co-Authors: Jacques Ameille, Nicole Rosenberg, Mireille Matrat, Alexis Descatha, Dominique Mompoint, Lounis Hamzi, Catherine Atassi, Manuela Vasile, Robert Garnier, Jean-claude Pairon

    Abstract:

    UNLABELLED: Purpose: Automobile mechanics have been exposed to asbestos in the past, mainly due to the presence of chrysotile asbestos in brakes and clutches. Despite the large number of automobile mechanics, little is known about the non-malignant respiratory Diseases observed in this population. The aim of this retrospective multicenter study was to analyse the frequency of pleural and parenchymal abnormalities on high-resolution computed tomography (HRCT) in a population of automobile mechanics. METHODS: The study population consisted of 103 automobile mechanics with no other source of occupational exposure to asbestos, referred to three occupational health departments in the Paris area for systematic screening of Asbestos-Related Diseases. All subjects were examined by HRCT and all images were reviewed separately by two independent readers; who in the case of disagreement discussed until they reached agreement. Multiple logistic regression models were constructed to investigate factors associated with pleural plaques. RESULTS: Pleural plaques were observed in five cases (4.9%) and interstitial abnormalities consistent with asbestosis were observed in one case. After adjustment for age, smoking status, and a history of non-Asbestos-Related respiratory Diseases, multiple logistic regression models showed a significant association between the duration of exposure to asbestos and pleural plaques. CONCLUSIONS: The asbestos exposure experienced by automobile mechanics may lead to pleural plaques. The low prevalence of non-malignant Asbestos-Related Diseases, using a very sensitive diagnostic tool, is in favor of a low cumulative exposure to asbestos in this population of workers.

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  • Asbestos-Related Diseases in Automobile Mechanics
    The Annals of Occupational Hygiene, 2011
    Co-Authors: Jacques Ameille, Nicole Rosenberg, Mireille Matrat, Alexis Descatha, Dominique Mompoint, Lounis Hamzi, Catherine Atassi, Manuela Vasile, Robert Garnier, Jean-claude Pairon

    Abstract:

    Purpose: Automobile mechanics have been exposed to asbestos in the past, mainly due to the presence of chrysotile asbestos in brakes and clutches. Despite the large number of automobile mechanics, little is known about the non-malignant respiratory Diseases observed in this population. The aim of this retrospective multicenter study was to analyse the frequency of pleural and parenchymal abnormalities on high-resolution computed tomography (HRCT) in a population of automobile mechanics. Methods: The study population consisted of 103 automobile mechanics with no other source of occupational exposure to asbestos, referred to three occupational health departments in the Paris area for systematic screening of Asbestos-Related Diseases. All subjects were examined by HRCTand all images were reviewed separately by two independent readers; who in the case of disagreement discussed until they reached agreement. Multiple logistic regression models were constructed to investigate factors associated with pleural plaques. Results: Pleural plaques were observed in five cases (4.9%) and interstitial abnormalities consistent with asbestosis were observed in one case. After adjustment for age, smoking status, and a history of non-Asbestos-Related respiratory Diseases, multiple logistic regression models showed a significant association between the duration of exposure to asbestos and pleural plaques. Conclusions: The asbestos exposure experienced by automobile mechanics may lead to pleural plaques. The low prevalence of non-malignant Asbestos-Related Diseases, using a very sensitive diagnostic tool, is in favor of a low cumulative exposure to asbestos in this population of workers.

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