Asparagus Racemosus

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Bishnu Pada Saha - One of the best experts on this subject based on the ideXlab platform.

  • Evaluation of antibacterial activity of Asparagus Racemosus Willd. root
    Phytotherapy research : PTR, 2000
    Co-Authors: Subhash C. Mandal, Nandy A, M. Pal, Bishnu Pada Saha
    Abstract:

    Different concentrations (50, 100, 150 microg/mL) of the methanol extract of the roots of Asparagus Racemosus Willd. showed considerable in vitro antibacterial efficacy against Escherichia coli, Shigella dysenteriae, Shigella sonnei, Shigella flexneri, Vibrio cholerae, Salmonella typhi, Salmonella typhimurium, Pseudomonas putida, Bacillus subtilis and Staphylococcus aureus. The effects produced by the methanol extract were compared with chloramphenicol.

  • Some pharmacognostical characteristics of Asparagus Racemosus willd, roots.
    Ancient science of life, 1996
    Co-Authors: Pulok K. Mukherjee, Nandy A, M. Pal, Bishnu Pada Saha
    Abstract:

    The macroscopic character of the roots physical constant values, extractive values, behaviour on treatment with different chemical reagents, fluorescence characters under ultra violet light after treatment with different chemical reagents of the powdered roots of Asparagus Racemosus Willd, (Fam. Liliaceae) were studied to fix some pharmacognostical parameters.

  • Physico -chemical characteristics of tincture from Asparagus Racemosus willd.
    Ancient science of life, 1996
    Co-Authors: Pulok K. Mukherjee, Nandy A, M. Pal, Bishnu Pada Saha
    Abstract:

    Various strength of alcohol were utilized for the preparation of tincture of Asparagus Racemosus roots by maceration for 7, 14 and 21 days. 50% (V/V) alcohol after 21 days of maceration showed maximum yield of total solid. The tinctures were evaluated by studying their different physico-chemical characteristics along with thin-Layer chromatography.

M. Pal - One of the best experts on this subject based on the ideXlab platform.

Subhash C. Mandal - One of the best experts on this subject based on the ideXlab platform.

  • Evaluation of antibacterial activity of Asparagus Racemosus Willd. root
    Phytotherapy research : PTR, 2000
    Co-Authors: Subhash C. Mandal, Nandy A, M. Pal, Bishnu Pada Saha
    Abstract:

    Different concentrations (50, 100, 150 microg/mL) of the methanol extract of the roots of Asparagus Racemosus Willd. showed considerable in vitro antibacterial efficacy against Escherichia coli, Shigella dysenteriae, Shigella sonnei, Shigella flexneri, Vibrio cholerae, Salmonella typhi, Salmonella typhimurium, Pseudomonas putida, Bacillus subtilis and Staphylococcus aureus. The effects produced by the methanol extract were compared with chloramphenicol.

  • Antitussive effect of Asparagus Racemosus root against sulfur dioxide-induced cough in mice
    Fitoterapia, 2000
    Co-Authors: Subhash C. Mandal, C. K. Ashok Kumar, S. Mohana Lakshmi, Sanghamitra Sinha, Thangaraju Murugesan, B.p. Saha, M. Pal
    Abstract:

    The methanol extract of Asparagus Racemosus root (200 and 400 mg/kg, p.o.) showed significant antitussive activity on sulfur dioxide-induced cough in mice, the cough inhibition (40.0 and 58.5%, respectively) being comparable to that of 10-20 mg/kg of codeine phosphate (36.0 and 55.4%, respectively).

Santi Tip-pyang - One of the best experts on this subject based on the ideXlab platform.

  • Identification of antioxidant compound from Asparagus Racemosus.
    Phytotherapy research : PTR, 2004
    Co-Authors: Nathathai Wiboonpun, Preecha Phuwapraisirisan, Santi Tip-pyang
    Abstract:

    Roots of Asparagus Racemosus were found to possess antioxidant property. DPPH autography-directed separation resulted in the identification of a new antioxidant compound named racemofuran (3) along with two known compounds asparagamine A (1) and racemosol (2). The structure of 3 was fully characterized by spectroscopic data (UV, MS, 1H NMR, 13C NMR, and 2D NMR). Racemofuran revealed antioxidant property against DPPH with IC50 value of 130 microM.

Ramesh Chandra - One of the best experts on this subject based on the ideXlab platform.

  • The effect of the aqueous extract of the roots of Asparagus Racemosus on hepatocarcinogenesis initiated by diethylnitrosamine.
    Phytotherapy research : PTR, 2008
    Co-Authors: Alka Agrawal, Meenakshi Sharma, Santosh Kumar Rai, Bharat Singh, Manisha Tiwari, Ramesh Chandra
    Abstract:

    Histopathological studies of the hepatic tissues of Wistar rats treated with diethylnitrosamine (DEN) (200 mg/kg b wt, i.p.) once a week for 2 weeks, followed by treatment with DDT, a tumor promoter (0.05% in diet) for 2 weeks and kept under observation for another 18 weeks, demonstrated the development of malignancy. Pretreatment of Wistar rats with the aqueous extract of the roots of Asparagus Racemosus prevented the incidence of hepatocarcinogenesis. Immunohistochemical staining of the hepatic tissues of rats treated with DEN showed the presence of p53+ foci (clusters of cells expressing the mutated p53 protein), whereas an absence of p53+ foci was observed in Wistar rats pretreated with the aqueous extract of the roots of Asparagus Racemosus. The microsections of the hepatic tissue of rats treated with DEN followed by treatment with the aqueous extract of Asparagus Racemosus showed an absence of p53+ foci. The results of the biochemical determinations also show that pretreatment of Wistar rats with the aqueous extract of Asparagus Racemosus leads to the amelioration of oxidative stress and hepatotoxicity brought about by treatment with DEN. These results prove that the aqueous extract of the roots of Asparagus Racemosus has the potential to act as an effective formulation to prevent hepatocarcinogenesis induced by treatment with DEN.