The Experts below are selected from a list of 318 Experts worldwide ranked by ideXlab platform

Vineta Fellman - One of the best experts on this subject based on the ideXlab platform.

  • Auditory Event-related potentials are related to cognition at preschool age after very preterm birth.
    Pediatric research, 2015
    Co-Authors: Holger Hövel, Eino Partanen, Eva Tideman, Karin Stjernqvist, Lena Hellström-westas, Minna Huotilainen, Vineta Fellman
    Abstract:

    Auditory Event-related potentials are related to cognition at preschool age after very preterm birth

  • perinatal cerebral insults alter Auditory Event related potentials
    Early Human Development, 2011
    Co-Authors: Eino Partanen, Minna Huotilainen, Vineta Fellman, Elena Kushnerenko, Jaana Leipälä
    Abstract:

    Background: Auditory Event-related potentials (AERPs) can be used as indices of neural information processing. Altered AERPs have been reported in children and young adults with frontal lobe infarction. Aim: To test the hypothesis that perinatal brain injury affects cortical Auditory processing. Methods: We assessed AERPs at term. 6 and 12 months of age in preterm infants [n = 9. median gestational age (GA) 27.9, range 23.9-30.0 wk], term infants with perinatal intracerebral hemorrhage (ICH) [n = 5, GA 40.3, range 37.4-42.3 wk], and term infants with perinatal asphyxia In [n = 4. GA 39.4. range 37.9-40.3 wk]. Healthy preterm (n = 16) and term infants (n = 22) served as controls. A harmonic tone of 500-Hz frequency was used as standard and of 750-Hz as deviant stimulus. Mean AERP amplitudes were calculated over 100 ms periods from 50 to 350 ms. The developmental outcome was followed until 2 years of age. Results: The term ICH (p = 0.012) and asphyxia (p = 0.0016) group had smaller or more negative responses to the deviant, resulting in smaller or more negative MMR amplitudes than those of the controls. The preterm ICH group did not differ significantly from their preterm born controls. MMR varied in all patient groups and was not associated with adverse outcome. Conclusion: AERP alterations suggest that perinatal cerebral insults affect cortical Auditory processing. (C) 2010 Elsevier Ireland Ltd. All rights reserved. (Less)

  • Early Auditory Event-Related Potentials are Accelerated at Preschool Age After Extremely Preterm Birth
    Pediatric Research, 2011
    Co-Authors: Holger Hövel, Eino Partanen, Karin Stjernqvist, Minna Huotilainen, Magnus Lindgren, Ingmar Rosén, Vineta Fellman
    Abstract:

    Background and aims: Auditory Event-related potentials (aERP) are neurophysiological correlates of higher cortical functions. Pathological aERP have been seen in children with various cognitive dysfunctions. Our aim was to study whether aERP in extremely preterm infants (EP) with high risk of dysfunction are different from late preterm (PC) and term-born controls (TC) at preschool age.

  • perinatal cerebral insults alter Auditory Event related potentials
    Archives of Disease in Childhood, 2011
    Co-Authors: Eino Partanen, Minna Huotilainen, Vineta Fellman, Elena Kushnerenko, Jaana Leipälä
    Abstract:

    Objective To test the hypothesis that perinatal brain injury affects cortical Auditory processing. Methods Auditory Event-related potentials (AERP) were assessed in preterm infants (n  =  9, median gestational age 27.9 weeks, range 23.9–30.0) and term infants (n  =  5, median gestational age 40.3 weeks, range 37.4–42.3) with perinatal intracerebral haemorrhage (ICH), and term infants with perinatal asphyxia (n  =  4, median gestational age 39.4 weeks, range 37.9–40.3). Two control groups were used, preterm infants without cerebral abnormality (n  =  9) and healthy term infants (n  =  22). An oddball paradigm was used with a harmonic tone of 500 Hz frequency as the standard and of 750 Hz frequency as the deviant stimulus. The preterm infants were studied at term, 6 and 12 months of corrected age, and the full-term infants within 17 days after birth, and at 6 and 12 months of age. Mean AERP amplitudes were calculated over the 150–250 and 250–350 ms periods, separately to standard tones preceding deviants and to the deviant tones. The neurological outcome was followed to 2 years of age. Results Term infants with asphyxia and ICH showed smaller responses than controls. Both the term and preterm ICH group showed more negative responses than controls. AERP alterations did not predict gross motor abnormalities at 2 years of age. Conclusions Altered AERP may indicate that perinatal cerebral insults affect cortical Auditory processing. Whether altered AERP predict cognitive dysfunction needs to be assessed in a study with extended follow-up.

  • Atypical Auditory Event-Related Potentials in Preterm Infants during the First Year of Life: A Possible Sign of Cognitive Dysfunction?
    Pediatric research, 2004
    Co-Authors: Vineta Fellman, Elena Kushnerenko, Kaija Mikkola, Rita Ceponiene, Jaana Leipälä, Risto Näätänen
    Abstract:

    Atypical Auditory Event-Related Potentials in Preterm Infants during the First Year of Life: A Possible Sign of Cognitive Dysfunction?

Risto Näätänen - One of the best experts on this subject based on the ideXlab platform.

  • Atypical Auditory Event-Related Potentials in Preterm Infants during the First Year of Life: A Possible Sign of Cognitive Dysfunction?
    Pediatric research, 2004
    Co-Authors: Vineta Fellman, Elena Kushnerenko, Kaija Mikkola, Rita Ceponiene, Jaana Leipälä, Risto Näätänen
    Abstract:

    Atypical Auditory Event-Related Potentials in Preterm Infants during the First Year of Life: A Possible Sign of Cognitive Dysfunction?

  • temporal integration intentional sound discrimination does not modulate stimulus driven processes in Auditory Event synthesis
    Clinical Neurophysiology, 2002
    Co-Authors: Elyse S Sussman, István Winkler, Risto Näätänen, Judith A Kreuzer, Marieke Saher, Walter Ritter
    Abstract:

    Abstract Objective : Our previous study showed that the Auditory context could influence whether two successive acoustic changes occurring within the temporal integration window (approximately 200ms) were pre-attentively encoded as a single Auditory Event or as two discrete Events (Cogn Brain Res 12 (2001) 431). The aim of the current study was to assess whether top-down processes could influence the stimulus-driven processes in determining what constitutes an Auditory Event. Methods : Electroencepholagram (EEG) was recorded from 11 scalp electrodes to frequently occurring standard and infrequently occurring deviant sounds. Within the stimulus blocks, deviants either occurred only in pairs (successive feature changes) or both singly and in pairs. Event-related potential indices of change and target detection, the mismatch negativity (MMN) and the N2b component, respectively, were compared with the simultaneously measured performance in discriminating the deviants. Results : Even though subjects could voluntarily distinguish the two successive Auditory feature changes from each other, which was also indicated by the elicitation of the N2b target-detection response, top-down processes did not modify the Event organization reflected by the MMN response. Conclusions : Top-down processes can extract elemental Auditory information from a single integrated acoustic Event, but the extraction occurs at a later processing stage than the one whose outcome is indexed by MMN. Significance : Initial processes of Auditory Event-formation are fully governed by the context within which the sounds occur. Perception of the deviants as two separate sound Events (the top-down effects) did not change the initial neural representation of the same deviants as one Event (indexed by the MMN), without a corresponding change in the stimulus-driven sound organization.

  • Children's Auditory Event-Related Potentials Index Sound Complexity and “Speechness”
    The International journal of neuroscience, 2001
    Co-Authors: Rita Ceponiene, Anna Shestakova, Polina Balan, Paavo Alku, Kiyoshi Yiaguchi, Risto Näätänen
    Abstract:

    Children's long-latency Auditory Event-related potential (LLAEP) structure differs from that of adults. Functional significance of childhood ERP components is largely unknown. In order to look for the functional correlates in adult and children's LLAEPs, stimulus-complexity effects were investigated in 8-10-year old children. To this end, Auditory ERPs to vowels, acoustically matched complex tones, and sinusoidal tones were recorded. All types of stimuli elicited P100-N250-N450 ERP complex. Differences between the sinusoidal and complex tones were confined to the P100 and N250 peaks, complex tones eliciting larger responses. Vowels elicited smaller-amplitude N250 but larger-amplitude N450 than the complex tones. Some stimulus-complexity effects observed for N250 in children corresponded to those observed for the N1 in adults, whereas the N450 peak exhibited behaviour resembling that of the adult ERP components subsequent to the N1 wave.

  • interstimulus interval and Auditory Event related potentials in children evidence for multiple generators
    Electroencephalography and Clinical Neurophysiology, 1998
    Co-Authors: R Ceponien, Marie Cheour, Risto Näätänen
    Abstract:

    In the present study, the component structure of Auditory Event-related potentials (ERP) was studied in children of 7-9 years old by presenting stimuli with different interstimulus intervals (ISI). A short-term Auditory sensory memory, as reflected by ISI effects on ERPs, was also studied. Auditory ERPs were recorded to brief unattended 1000 Hz frequent, 'standard' and 1100 Hz rare, 'deviant' (probability 0.1) tone stimuli with ISIs of 350, 700 and 1400 ms (in separate blocks). With the 350 ms-ISI, the ERP waveform to the standard stimulus consisted of P100-N250 peaks. With the two longer ISIs, in addition, the frontocentral N160 and N460 peaks were observed. Results suggested that N160, found with the longer ISIs, is a correlate of the adult Auditory N1. In difference waves, obtained by subtracting ERP to standard stimuli from ERP to deviant stimuli, two negativities were revealed. The first was the mismatch negativity (MMN), which is elicited by any discriminable change in repetitive Auditory input. The MMN data suggested that neural traces of Auditory sensory memory lasted for at least 1400 ms, probably considerably longer, as no MMN attenuation was found across the ISIs used. The second, later negativity was similar to MMN in all aspects, except for the scalp distribution, which was posterior to that of the MMN.

  • Temporal constraints of Auditory Event synthesis: evidence from ERPs.
    Neuroreport, 1998
    Co-Authors: István Winkler, István Czigler, Maria Jaramillo, Petri Paavilainen, Risto Näätänen
    Abstract:

    The temporal constraints of Auditory Event synthesis were investigated using Event-related potentials. Standard stimuli consisted of an initial constant-frequency segment followed by a frequency glide. Occasionally, stimuli deviating from this standard both in intensity and within the direction of the glide were presented in the otherwise repetitive sound sequence. Previous results suggested that such 'double' deviants elicit only a single mismatch negativity (MMN) if the two temporally separate deviant elements were integrated within a common unit. Two successive MMNs were elicited by double deviants when the initial constant-frequency segment of the sound was 250 ms long, but only one when this segment was 150 ms in duration. The results support the hypothesis that the Auditory input is processed in approximately 200 ms long temporal integration windows.

Eino Partanen - One of the best experts on this subject based on the ideXlab platform.

  • Auditory Event-related potentials are related to cognition at preschool age after very preterm birth.
    Pediatric research, 2015
    Co-Authors: Holger Hövel, Eino Partanen, Eva Tideman, Karin Stjernqvist, Lena Hellström-westas, Minna Huotilainen, Vineta Fellman
    Abstract:

    Auditory Event-related potentials are related to cognition at preschool age after very preterm birth

  • perinatal cerebral insults alter Auditory Event related potentials
    Early Human Development, 2011
    Co-Authors: Eino Partanen, Minna Huotilainen, Vineta Fellman, Elena Kushnerenko, Jaana Leipälä
    Abstract:

    Background: Auditory Event-related potentials (AERPs) can be used as indices of neural information processing. Altered AERPs have been reported in children and young adults with frontal lobe infarction. Aim: To test the hypothesis that perinatal brain injury affects cortical Auditory processing. Methods: We assessed AERPs at term. 6 and 12 months of age in preterm infants [n = 9. median gestational age (GA) 27.9, range 23.9-30.0 wk], term infants with perinatal intracerebral hemorrhage (ICH) [n = 5, GA 40.3, range 37.4-42.3 wk], and term infants with perinatal asphyxia In [n = 4. GA 39.4. range 37.9-40.3 wk]. Healthy preterm (n = 16) and term infants (n = 22) served as controls. A harmonic tone of 500-Hz frequency was used as standard and of 750-Hz as deviant stimulus. Mean AERP amplitudes were calculated over 100 ms periods from 50 to 350 ms. The developmental outcome was followed until 2 years of age. Results: The term ICH (p = 0.012) and asphyxia (p = 0.0016) group had smaller or more negative responses to the deviant, resulting in smaller or more negative MMR amplitudes than those of the controls. The preterm ICH group did not differ significantly from their preterm born controls. MMR varied in all patient groups and was not associated with adverse outcome. Conclusion: AERP alterations suggest that perinatal cerebral insults affect cortical Auditory processing. (C) 2010 Elsevier Ireland Ltd. All rights reserved. (Less)

  • Early Auditory Event-Related Potentials are Accelerated at Preschool Age After Extremely Preterm Birth
    Pediatric Research, 2011
    Co-Authors: Holger Hövel, Eino Partanen, Karin Stjernqvist, Minna Huotilainen, Magnus Lindgren, Ingmar Rosén, Vineta Fellman
    Abstract:

    Background and aims: Auditory Event-related potentials (aERP) are neurophysiological correlates of higher cortical functions. Pathological aERP have been seen in children with various cognitive dysfunctions. Our aim was to study whether aERP in extremely preterm infants (EP) with high risk of dysfunction are different from late preterm (PC) and term-born controls (TC) at preschool age.

  • perinatal cerebral insults alter Auditory Event related potentials
    Archives of Disease in Childhood, 2011
    Co-Authors: Eino Partanen, Minna Huotilainen, Vineta Fellman, Elena Kushnerenko, Jaana Leipälä
    Abstract:

    Objective To test the hypothesis that perinatal brain injury affects cortical Auditory processing. Methods Auditory Event-related potentials (AERP) were assessed in preterm infants (n  =  9, median gestational age 27.9 weeks, range 23.9–30.0) and term infants (n  =  5, median gestational age 40.3 weeks, range 37.4–42.3) with perinatal intracerebral haemorrhage (ICH), and term infants with perinatal asphyxia (n  =  4, median gestational age 39.4 weeks, range 37.9–40.3). Two control groups were used, preterm infants without cerebral abnormality (n  =  9) and healthy term infants (n  =  22). An oddball paradigm was used with a harmonic tone of 500 Hz frequency as the standard and of 750 Hz frequency as the deviant stimulus. The preterm infants were studied at term, 6 and 12 months of corrected age, and the full-term infants within 17 days after birth, and at 6 and 12 months of age. Mean AERP amplitudes were calculated over the 150–250 and 250–350 ms periods, separately to standard tones preceding deviants and to the deviant tones. The neurological outcome was followed to 2 years of age. Results Term infants with asphyxia and ICH showed smaller responses than controls. Both the term and preterm ICH group showed more negative responses than controls. AERP alterations did not predict gross motor abnormalities at 2 years of age. Conclusions Altered AERP may indicate that perinatal cerebral insults affect cortical Auditory processing. Whether altered AERP predict cognitive dysfunction needs to be assessed in a study with extended follow-up.

Minna Huotilainen - One of the best experts on this subject based on the ideXlab platform.

  • Auditory Event-related potentials are related to cognition at preschool age after very preterm birth.
    Pediatric research, 2015
    Co-Authors: Holger Hövel, Eino Partanen, Eva Tideman, Karin Stjernqvist, Lena Hellström-westas, Minna Huotilainen, Vineta Fellman
    Abstract:

    Auditory Event-related potentials are related to cognition at preschool age after very preterm birth

  • perinatal cerebral insults alter Auditory Event related potentials
    Early Human Development, 2011
    Co-Authors: Eino Partanen, Minna Huotilainen, Vineta Fellman, Elena Kushnerenko, Jaana Leipälä
    Abstract:

    Background: Auditory Event-related potentials (AERPs) can be used as indices of neural information processing. Altered AERPs have been reported in children and young adults with frontal lobe infarction. Aim: To test the hypothesis that perinatal brain injury affects cortical Auditory processing. Methods: We assessed AERPs at term. 6 and 12 months of age in preterm infants [n = 9. median gestational age (GA) 27.9, range 23.9-30.0 wk], term infants with perinatal intracerebral hemorrhage (ICH) [n = 5, GA 40.3, range 37.4-42.3 wk], and term infants with perinatal asphyxia In [n = 4. GA 39.4. range 37.9-40.3 wk]. Healthy preterm (n = 16) and term infants (n = 22) served as controls. A harmonic tone of 500-Hz frequency was used as standard and of 750-Hz as deviant stimulus. Mean AERP amplitudes were calculated over 100 ms periods from 50 to 350 ms. The developmental outcome was followed until 2 years of age. Results: The term ICH (p = 0.012) and asphyxia (p = 0.0016) group had smaller or more negative responses to the deviant, resulting in smaller or more negative MMR amplitudes than those of the controls. The preterm ICH group did not differ significantly from their preterm born controls. MMR varied in all patient groups and was not associated with adverse outcome. Conclusion: AERP alterations suggest that perinatal cerebral insults affect cortical Auditory processing. (C) 2010 Elsevier Ireland Ltd. All rights reserved. (Less)

  • Early Auditory Event-Related Potentials are Accelerated at Preschool Age After Extremely Preterm Birth
    Pediatric Research, 2011
    Co-Authors: Holger Hövel, Eino Partanen, Karin Stjernqvist, Minna Huotilainen, Magnus Lindgren, Ingmar Rosén, Vineta Fellman
    Abstract:

    Background and aims: Auditory Event-related potentials (aERP) are neurophysiological correlates of higher cortical functions. Pathological aERP have been seen in children with various cognitive dysfunctions. Our aim was to study whether aERP in extremely preterm infants (EP) with high risk of dysfunction are different from late preterm (PC) and term-born controls (TC) at preschool age.

  • perinatal cerebral insults alter Auditory Event related potentials
    Archives of Disease in Childhood, 2011
    Co-Authors: Eino Partanen, Minna Huotilainen, Vineta Fellman, Elena Kushnerenko, Jaana Leipälä
    Abstract:

    Objective To test the hypothesis that perinatal brain injury affects cortical Auditory processing. Methods Auditory Event-related potentials (AERP) were assessed in preterm infants (n  =  9, median gestational age 27.9 weeks, range 23.9–30.0) and term infants (n  =  5, median gestational age 40.3 weeks, range 37.4–42.3) with perinatal intracerebral haemorrhage (ICH), and term infants with perinatal asphyxia (n  =  4, median gestational age 39.4 weeks, range 37.9–40.3). Two control groups were used, preterm infants without cerebral abnormality (n  =  9) and healthy term infants (n  =  22). An oddball paradigm was used with a harmonic tone of 500 Hz frequency as the standard and of 750 Hz frequency as the deviant stimulus. The preterm infants were studied at term, 6 and 12 months of corrected age, and the full-term infants within 17 days after birth, and at 6 and 12 months of age. Mean AERP amplitudes were calculated over the 150–250 and 250–350 ms periods, separately to standard tones preceding deviants and to the deviant tones. The neurological outcome was followed to 2 years of age. Results Term infants with asphyxia and ICH showed smaller responses than controls. Both the term and preterm ICH group showed more negative responses than controls. AERP alterations did not predict gross motor abnormalities at 2 years of age. Conclusions Altered AERP may indicate that perinatal cerebral insults affect cortical Auditory processing. Whether altered AERP predict cognitive dysfunction needs to be assessed in a study with extended follow-up.

Holger Hövel - One of the best experts on this subject based on the ideXlab platform.