The Experts below are selected from a list of 234 Experts worldwide ranked by ideXlab platform
Xunzhang Wang - One of the best experts on this subject based on the ideXlab platform.
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Identification of Differential mRNA and lncRNA Expression in AcMNPV- Infected Sf9 Cells
2020Co-Authors: Tiejun Zhao, Riqiang Deng, Mengqiu Chen, Xunzhang WangAbstract:Abstract Autographa californica multiple Nucleopolyhedrovirus (AcMNPV) is the archetypal species of the alphabaculovirus. Sf9 are the ovarian cells of their host—Spodoptera frugiperda. In this study, a total of 3,463 pieces of time-series differentially expressed RNA are identified, including 1,200 mRNA and 2,263 lncRNA, with high-throughput sequencing technology using samples collected from Sf9 cells at different time points after AcMNPV infection. The result could provide a reference for the further study of the interaction and regulatory mechanism between the virus and the host.
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A MicroRNA Encoded by Autographa californica Nucleopolyhedrovirus Regulates Expression of Viral Gene ODV-E25
2016Co-Authors: Mengxiao Zhu, Riqiang Deng, Jinwen Wang, Peiwen Xiong, Hai Liang, Xunzhang WangAbstract:Baculovirus-encoded microRNAs (miRNAs) have been described in Bombyx mori nucleopolyhedrovirus; however, most of their functions remain unclear. Here we report the identification and characterization of an miRNA encoded by Autographa califor-nica nucleopolyhedrovirus. The identified miRNA, AcMNPV-miR-1, perfectly matched a segment in the coding sequence of the viral gene ODV-E25 and downregulated ODV-E25mRNA expression, which likely resulted in a reduction of infectious budded virions and accelerated the formation of occlusion-derived virions. MicroRNAs (miRNAs) are small, noncoding RNAs between19 and 24 nucleotides (nt) in size that play a posttranscrip-tional regulatory role in gene expression and cellular processes (1). Although virus-encoded miRNAs have been described in mam-malian viruses, such as Epstein-Barr virus (2) and simian virus 40 (3), the miRNAs encoded by baculovirus, which infect numerous beneficial insects and agricultural pests, have only been investi-gated in Bombyx mori nucleopolyhedrosis virus (BmNPV) (4, 5). Investigation of the miRNAs encoded by these viruses would help to explain the role of miRNAs in host-pathogen interactions. This study identifies the first miRNA encoded by Autographa califor
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a microrna encoded by Autographa californica nucleopolyhedrovirus regulates expression of viral gene odv e25
Journal of Virology, 2013Co-Authors: Mengxiao Zhu, Riqiang Deng, Jinwen Wang, Peiwen Xiong, Hai Liang, Xunzhang WangAbstract:Baculovirus-encoded microRNAs (miRNAs) have been described in Bombyx mori nucleopolyhedrovirus; however, most of their functions remain unclear. Here we report the identification and characterization of an miRNA encoded by Autographa californica nucleopolyhedrovirus. The identified miRNA, AcMNPV-miR-1, perfectly matched a segment in the coding sequence of the viral gene ODV-E25 and downregulated ODV-E25 mRNA expression, which likely resulted in a reduction of infectious budded virions and accelerated the formation of occlusion-derived virions.
Mengxiao Zhu - One of the best experts on this subject based on the ideXlab platform.
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A MicroRNA Encoded by Autographa californica Nucleopolyhedrovirus Regulates Expression of Viral Gene ODV-E25
2016Co-Authors: Mengxiao Zhu, Riqiang Deng, Jinwen Wang, Peiwen Xiong, Hai Liang, Xunzhang WangAbstract:Baculovirus-encoded microRNAs (miRNAs) have been described in Bombyx mori nucleopolyhedrovirus; however, most of their functions remain unclear. Here we report the identification and characterization of an miRNA encoded by Autographa califor-nica nucleopolyhedrovirus. The identified miRNA, AcMNPV-miR-1, perfectly matched a segment in the coding sequence of the viral gene ODV-E25 and downregulated ODV-E25mRNA expression, which likely resulted in a reduction of infectious budded virions and accelerated the formation of occlusion-derived virions. MicroRNAs (miRNAs) are small, noncoding RNAs between19 and 24 nucleotides (nt) in size that play a posttranscrip-tional regulatory role in gene expression and cellular processes (1). Although virus-encoded miRNAs have been described in mam-malian viruses, such as Epstein-Barr virus (2) and simian virus 40 (3), the miRNAs encoded by baculovirus, which infect numerous beneficial insects and agricultural pests, have only been investi-gated in Bombyx mori nucleopolyhedrosis virus (BmNPV) (4, 5). Investigation of the miRNAs encoded by these viruses would help to explain the role of miRNAs in host-pathogen interactions. This study identifies the first miRNA encoded by Autographa califor
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a microrna encoded by Autographa californica nucleopolyhedrovirus regulates expression of viral gene odv e25
Journal of Virology, 2013Co-Authors: Mengxiao Zhu, Riqiang Deng, Jinwen Wang, Peiwen Xiong, Hai Liang, Xunzhang WangAbstract:Baculovirus-encoded microRNAs (miRNAs) have been described in Bombyx mori nucleopolyhedrovirus; however, most of their functions remain unclear. Here we report the identification and characterization of an miRNA encoded by Autographa californica nucleopolyhedrovirus. The identified miRNA, AcMNPV-miR-1, perfectly matched a segment in the coding sequence of the viral gene ODV-E25 and downregulated ODV-E25 mRNA expression, which likely resulted in a reduction of infectious budded virions and accelerated the formation of occlusion-derived virions.
Riqiang Deng - One of the best experts on this subject based on the ideXlab platform.
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Identification of Differential mRNA and lncRNA Expression in AcMNPV- Infected Sf9 Cells
2020Co-Authors: Tiejun Zhao, Riqiang Deng, Mengqiu Chen, Xunzhang WangAbstract:Abstract Autographa californica multiple Nucleopolyhedrovirus (AcMNPV) is the archetypal species of the alphabaculovirus. Sf9 are the ovarian cells of their host—Spodoptera frugiperda. In this study, a total of 3,463 pieces of time-series differentially expressed RNA are identified, including 1,200 mRNA and 2,263 lncRNA, with high-throughput sequencing technology using samples collected from Sf9 cells at different time points after AcMNPV infection. The result could provide a reference for the further study of the interaction and regulatory mechanism between the virus and the host.
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A MicroRNA Encoded by Autographa californica Nucleopolyhedrovirus Regulates Expression of Viral Gene ODV-E25
2016Co-Authors: Mengxiao Zhu, Riqiang Deng, Jinwen Wang, Peiwen Xiong, Hai Liang, Xunzhang WangAbstract:Baculovirus-encoded microRNAs (miRNAs) have been described in Bombyx mori nucleopolyhedrovirus; however, most of their functions remain unclear. Here we report the identification and characterization of an miRNA encoded by Autographa califor-nica nucleopolyhedrovirus. The identified miRNA, AcMNPV-miR-1, perfectly matched a segment in the coding sequence of the viral gene ODV-E25 and downregulated ODV-E25mRNA expression, which likely resulted in a reduction of infectious budded virions and accelerated the formation of occlusion-derived virions. MicroRNAs (miRNAs) are small, noncoding RNAs between19 and 24 nucleotides (nt) in size that play a posttranscrip-tional regulatory role in gene expression and cellular processes (1). Although virus-encoded miRNAs have been described in mam-malian viruses, such as Epstein-Barr virus (2) and simian virus 40 (3), the miRNAs encoded by baculovirus, which infect numerous beneficial insects and agricultural pests, have only been investi-gated in Bombyx mori nucleopolyhedrosis virus (BmNPV) (4, 5). Investigation of the miRNAs encoded by these viruses would help to explain the role of miRNAs in host-pathogen interactions. This study identifies the first miRNA encoded by Autographa califor
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a microrna encoded by Autographa californica nucleopolyhedrovirus regulates expression of viral gene odv e25
Journal of Virology, 2013Co-Authors: Mengxiao Zhu, Riqiang Deng, Jinwen Wang, Peiwen Xiong, Hai Liang, Xunzhang WangAbstract:Baculovirus-encoded microRNAs (miRNAs) have been described in Bombyx mori nucleopolyhedrovirus; however, most of their functions remain unclear. Here we report the identification and characterization of an miRNA encoded by Autographa californica nucleopolyhedrovirus. The identified miRNA, AcMNPV-miR-1, perfectly matched a segment in the coding sequence of the viral gene ODV-E25 and downregulated ODV-E25 mRNA expression, which likely resulted in a reduction of infectious budded virions and accelerated the formation of occlusion-derived virions.
Hai Liang - One of the best experts on this subject based on the ideXlab platform.
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A MicroRNA Encoded by Autographa californica Nucleopolyhedrovirus Regulates Expression of Viral Gene ODV-E25
2016Co-Authors: Mengxiao Zhu, Riqiang Deng, Jinwen Wang, Peiwen Xiong, Hai Liang, Xunzhang WangAbstract:Baculovirus-encoded microRNAs (miRNAs) have been described in Bombyx mori nucleopolyhedrovirus; however, most of their functions remain unclear. Here we report the identification and characterization of an miRNA encoded by Autographa califor-nica nucleopolyhedrovirus. The identified miRNA, AcMNPV-miR-1, perfectly matched a segment in the coding sequence of the viral gene ODV-E25 and downregulated ODV-E25mRNA expression, which likely resulted in a reduction of infectious budded virions and accelerated the formation of occlusion-derived virions. MicroRNAs (miRNAs) are small, noncoding RNAs between19 and 24 nucleotides (nt) in size that play a posttranscrip-tional regulatory role in gene expression and cellular processes (1). Although virus-encoded miRNAs have been described in mam-malian viruses, such as Epstein-Barr virus (2) and simian virus 40 (3), the miRNAs encoded by baculovirus, which infect numerous beneficial insects and agricultural pests, have only been investi-gated in Bombyx mori nucleopolyhedrosis virus (BmNPV) (4, 5). Investigation of the miRNAs encoded by these viruses would help to explain the role of miRNAs in host-pathogen interactions. This study identifies the first miRNA encoded by Autographa califor
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a microrna encoded by Autographa californica nucleopolyhedrovirus regulates expression of viral gene odv e25
Journal of Virology, 2013Co-Authors: Mengxiao Zhu, Riqiang Deng, Jinwen Wang, Peiwen Xiong, Hai Liang, Xunzhang WangAbstract:Baculovirus-encoded microRNAs (miRNAs) have been described in Bombyx mori nucleopolyhedrovirus; however, most of their functions remain unclear. Here we report the identification and characterization of an miRNA encoded by Autographa californica nucleopolyhedrovirus. The identified miRNA, AcMNPV-miR-1, perfectly matched a segment in the coding sequence of the viral gene ODV-E25 and downregulated ODV-E25 mRNA expression, which likely resulted in a reduction of infectious budded virions and accelerated the formation of occlusion-derived virions.
Peiwen Xiong - One of the best experts on this subject based on the ideXlab platform.
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A MicroRNA Encoded by Autographa californica Nucleopolyhedrovirus Regulates Expression of Viral Gene ODV-E25
2016Co-Authors: Mengxiao Zhu, Riqiang Deng, Jinwen Wang, Peiwen Xiong, Hai Liang, Xunzhang WangAbstract:Baculovirus-encoded microRNAs (miRNAs) have been described in Bombyx mori nucleopolyhedrovirus; however, most of their functions remain unclear. Here we report the identification and characterization of an miRNA encoded by Autographa califor-nica nucleopolyhedrovirus. The identified miRNA, AcMNPV-miR-1, perfectly matched a segment in the coding sequence of the viral gene ODV-E25 and downregulated ODV-E25mRNA expression, which likely resulted in a reduction of infectious budded virions and accelerated the formation of occlusion-derived virions. MicroRNAs (miRNAs) are small, noncoding RNAs between19 and 24 nucleotides (nt) in size that play a posttranscrip-tional regulatory role in gene expression and cellular processes (1). Although virus-encoded miRNAs have been described in mam-malian viruses, such as Epstein-Barr virus (2) and simian virus 40 (3), the miRNAs encoded by baculovirus, which infect numerous beneficial insects and agricultural pests, have only been investi-gated in Bombyx mori nucleopolyhedrosis virus (BmNPV) (4, 5). Investigation of the miRNAs encoded by these viruses would help to explain the role of miRNAs in host-pathogen interactions. This study identifies the first miRNA encoded by Autographa califor
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a microrna encoded by Autographa californica nucleopolyhedrovirus regulates expression of viral gene odv e25
Journal of Virology, 2013Co-Authors: Mengxiao Zhu, Riqiang Deng, Jinwen Wang, Peiwen Xiong, Hai Liang, Xunzhang WangAbstract:Baculovirus-encoded microRNAs (miRNAs) have been described in Bombyx mori nucleopolyhedrovirus; however, most of their functions remain unclear. Here we report the identification and characterization of an miRNA encoded by Autographa californica nucleopolyhedrovirus. The identified miRNA, AcMNPV-miR-1, perfectly matched a segment in the coding sequence of the viral gene ODV-E25 and downregulated ODV-E25 mRNA expression, which likely resulted in a reduction of infectious budded virions and accelerated the formation of occlusion-derived virions.
