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Nilima N. Dongre - One of the best experts on this subject based on the ideXlab platform.

  • Biochemical Effects of Lead Exposure on Systolic & Diastolic Blood Pressure, Heme Biosynthesis and Hematological Parameters in Automobile Workers of North Karnataka (India)
    Indian Journal of Clinical Biochemistry, 2011
    Co-Authors: Nilima N. Dongre, Arun J. Patil, Jeevan G Ambekar, Adinath N. Suryakar, Dileep B. Rathi
    Abstract:

    The purpose of this study was to find out the effect of lead exposure on systolic and diastolic blood pressure, heme biosynthesis related and hematological parameters of Automobile Workers. For this study 30 Automobile Workers were selected and compared with 30 age matched healthy control subjects. Significantly increased blood lead (364%, P  

  • biochemical effects of lead exposure on systolic diastolic blood pressure heme biosynthesis and hematological parameters in Automobile Workers of north karnataka india
    Indian Journal of Clinical Biochemistry, 2011
    Co-Authors: Nilima N. Dongre, A. N. Suryakar, Arun J. Patil, Jeevan G Ambekar, Dileep Rathi
    Abstract:

    The purpose of this study was to find out the effect of lead exposure on systolic and diastolic blood pressure, heme biosynthesis related and hematological parameters of Automobile Workers. For this study 30 Automobile Workers were selected and compared with 30 age matched healthy control subjects. Significantly increased blood lead (364%, P < 0.001) and urinary lead (176%, P < 0.001) levels were observed in Automobile Workers (study group) as compared to controls. Systolic blood pressure (5.32%, P < 0.05) and diastolic blood pressure (5.87%, P < 0.05) were significantly increased in the Automobile Workers as compared to controls. The significantly decreased non-activated erythrocyte δ-aminolevulinic acid dehydratase (δ-ALAD) (−18.51%, P < 0.01) and activated δ-ALAD (−13.29%, P < 0.05) levels were observed in Automobile Workers as compared to normal healthy control subjects. But the ratio of activated/non-activated δ-ALAD was significantly increased (43.83%, P < 0.001) in Automobile Workers as compared to controls. Excretions of δ-aminolevulinic acid (83.78%, P < 0.001) and porphobilinogen (37%, P < 0.001) in urine were significantly increased in the study group as compared to the controls. In Automobile Workers heamoglobin (−11.51%, P < 0.001), hematocrit (−4.06%, P < 0.05), mean corpuscle volume (−3.34%, P < 0.05), mean corpuscle hemoglobin (−5.66%, P < 0.01), mean corpuscle hemoglobin concentration (−7.67%, P < 0.001), red blood cell count (−14.6%, P < 0.001) were significantly decreased and total white blood cell count (11.44%, P < 0.05) increased as compared to the controls. The results of this study clearly indicate that the absorption of lead is more in Automobile Workers and it affects on blood pressure, heme biosynthesis and hematological parameters observed in this study group.

  • Occupational lead exposure in Automobile Workers in North Karnataka (India): effect on liver and kidney functions.
    Journal of the Medical Sciences, 2010
    Co-Authors: Nilima N. Dongre, A. N. Suryakar, Arun J. Patil, Dileep B. Rathi
    Abstract:

    We studied liver and kidney function tests of occupational lead exposed Automobile Workers (N = 30), and normal healthy control subjects (N = 30), all 20 to 45 years of age, from Bijapur, North Karnataka (India). Venous blood and random urine samples were collected from both groups. The blood lead [PbB] (364%) and urinary lead [PbU] (176%) levels were significantly increased in Automobile Workers as compared with the controls. Liver function test parameters, i.e. Serum Aspartate Transaminase [AST] (23.88%), Alanine Transaminase [ALT] (24.03%), Alkaline Phosphatase [ALP] (17.99%), Total Bilirubin (45.83%), and Gamma glutamyl Transferase [GGT] (44.75%) were significantly increased in Automobile Workers as compared with the control group. Serum total protein, albumin, globulin, and A/ G ratio were not significantly altered in study group as compared with control subjects. In the kidney function tests levels of blood urea (26%), serum uric acid (13.11%) and serum creatinine (12.5%) were significantly increased in Automobile Workers as compared to control group. Increased PbB values in study group indicate the greater rate of lead absorption and impairment of liver and kidney functions in occupational lead-exposed Automobile Workers from Bijapur, North Karnataka (India).

Dileep Rathi - One of the best experts on this subject based on the ideXlab platform.

  • biochemical effects of lead exposure on systolic diastolic blood pressure heme biosynthesis and hematological parameters in Automobile Workers of north karnataka india
    Indian Journal of Clinical Biochemistry, 2011
    Co-Authors: Nilima N. Dongre, A. N. Suryakar, Arun J. Patil, Jeevan G Ambekar, Dileep Rathi
    Abstract:

    The purpose of this study was to find out the effect of lead exposure on systolic and diastolic blood pressure, heme biosynthesis related and hematological parameters of Automobile Workers. For this study 30 Automobile Workers were selected and compared with 30 age matched healthy control subjects. Significantly increased blood lead (364%, P < 0.001) and urinary lead (176%, P < 0.001) levels were observed in Automobile Workers (study group) as compared to controls. Systolic blood pressure (5.32%, P < 0.05) and diastolic blood pressure (5.87%, P < 0.05) were significantly increased in the Automobile Workers as compared to controls. The significantly decreased non-activated erythrocyte δ-aminolevulinic acid dehydratase (δ-ALAD) (−18.51%, P < 0.01) and activated δ-ALAD (−13.29%, P < 0.05) levels were observed in Automobile Workers as compared to normal healthy control subjects. But the ratio of activated/non-activated δ-ALAD was significantly increased (43.83%, P < 0.001) in Automobile Workers as compared to controls. Excretions of δ-aminolevulinic acid (83.78%, P < 0.001) and porphobilinogen (37%, P < 0.001) in urine were significantly increased in the study group as compared to the controls. In Automobile Workers heamoglobin (−11.51%, P < 0.001), hematocrit (−4.06%, P < 0.05), mean corpuscle volume (−3.34%, P < 0.05), mean corpuscle hemoglobin (−5.66%, P < 0.01), mean corpuscle hemoglobin concentration (−7.67%, P < 0.001), red blood cell count (−14.6%, P < 0.001) were significantly decreased and total white blood cell count (11.44%, P < 0.05) increased as compared to the controls. The results of this study clearly indicate that the absorption of lead is more in Automobile Workers and it affects on blood pressure, heme biosynthesis and hematological parameters observed in this study group.

Dileep B. Rathi - One of the best experts on this subject based on the ideXlab platform.

  • Biochemical Effects of Lead Exposure on Systolic & Diastolic Blood Pressure, Heme Biosynthesis and Hematological Parameters in Automobile Workers of North Karnataka (India)
    Indian Journal of Clinical Biochemistry, 2011
    Co-Authors: Nilima N. Dongre, Arun J. Patil, Jeevan G Ambekar, Adinath N. Suryakar, Dileep B. Rathi
    Abstract:

    The purpose of this study was to find out the effect of lead exposure on systolic and diastolic blood pressure, heme biosynthesis related and hematological parameters of Automobile Workers. For this study 30 Automobile Workers were selected and compared with 30 age matched healthy control subjects. Significantly increased blood lead (364%, P  

  • Occupational lead exposure in Automobile Workers in North Karnataka (India): effect on liver and kidney functions.
    Journal of the Medical Sciences, 2010
    Co-Authors: Nilima N. Dongre, A. N. Suryakar, Arun J. Patil, Dileep B. Rathi
    Abstract:

    We studied liver and kidney function tests of occupational lead exposed Automobile Workers (N = 30), and normal healthy control subjects (N = 30), all 20 to 45 years of age, from Bijapur, North Karnataka (India). Venous blood and random urine samples were collected from both groups. The blood lead [PbB] (364%) and urinary lead [PbU] (176%) levels were significantly increased in Automobile Workers as compared with the controls. Liver function test parameters, i.e. Serum Aspartate Transaminase [AST] (23.88%), Alanine Transaminase [ALT] (24.03%), Alkaline Phosphatase [ALP] (17.99%), Total Bilirubin (45.83%), and Gamma glutamyl Transferase [GGT] (44.75%) were significantly increased in Automobile Workers as compared with the control group. Serum total protein, albumin, globulin, and A/ G ratio were not significantly altered in study group as compared with control subjects. In the kidney function tests levels of blood urea (26%), serum uric acid (13.11%) and serum creatinine (12.5%) were significantly increased in Automobile Workers as compared to control group. Increased PbB values in study group indicate the greater rate of lead absorption and impairment of liver and kidney functions in occupational lead-exposed Automobile Workers from Bijapur, North Karnataka (India).

Jeevan G Ambekar - One of the best experts on this subject based on the ideXlab platform.

  • Biochemical Effects of Lead Exposure on Systolic & Diastolic Blood Pressure, Heme Biosynthesis and Hematological Parameters in Automobile Workers of North Karnataka (India)
    Indian Journal of Clinical Biochemistry, 2011
    Co-Authors: Nilima N. Dongre, Arun J. Patil, Jeevan G Ambekar, Adinath N. Suryakar, Dileep B. Rathi
    Abstract:

    The purpose of this study was to find out the effect of lead exposure on systolic and diastolic blood pressure, heme biosynthesis related and hematological parameters of Automobile Workers. For this study 30 Automobile Workers were selected and compared with 30 age matched healthy control subjects. Significantly increased blood lead (364%, P  

  • biochemical effects of lead exposure on systolic diastolic blood pressure heme biosynthesis and hematological parameters in Automobile Workers of north karnataka india
    Indian Journal of Clinical Biochemistry, 2011
    Co-Authors: Nilima N. Dongre, A. N. Suryakar, Arun J. Patil, Jeevan G Ambekar, Dileep Rathi
    Abstract:

    The purpose of this study was to find out the effect of lead exposure on systolic and diastolic blood pressure, heme biosynthesis related and hematological parameters of Automobile Workers. For this study 30 Automobile Workers were selected and compared with 30 age matched healthy control subjects. Significantly increased blood lead (364%, P < 0.001) and urinary lead (176%, P < 0.001) levels were observed in Automobile Workers (study group) as compared to controls. Systolic blood pressure (5.32%, P < 0.05) and diastolic blood pressure (5.87%, P < 0.05) were significantly increased in the Automobile Workers as compared to controls. The significantly decreased non-activated erythrocyte δ-aminolevulinic acid dehydratase (δ-ALAD) (−18.51%, P < 0.01) and activated δ-ALAD (−13.29%, P < 0.05) levels were observed in Automobile Workers as compared to normal healthy control subjects. But the ratio of activated/non-activated δ-ALAD was significantly increased (43.83%, P < 0.001) in Automobile Workers as compared to controls. Excretions of δ-aminolevulinic acid (83.78%, P < 0.001) and porphobilinogen (37%, P < 0.001) in urine were significantly increased in the study group as compared to the controls. In Automobile Workers heamoglobin (−11.51%, P < 0.001), hematocrit (−4.06%, P < 0.05), mean corpuscle volume (−3.34%, P < 0.05), mean corpuscle hemoglobin (−5.66%, P < 0.01), mean corpuscle hemoglobin concentration (−7.67%, P < 0.001), red blood cell count (−14.6%, P < 0.001) were significantly decreased and total white blood cell count (11.44%, P < 0.05) increased as compared to the controls. The results of this study clearly indicate that the absorption of lead is more in Automobile Workers and it affects on blood pressure, heme biosynthesis and hematological parameters observed in this study group.

Arun J. Patil - One of the best experts on this subject based on the ideXlab platform.

  • Biochemical Effects of Lead Exposure on Systolic & Diastolic Blood Pressure, Heme Biosynthesis and Hematological Parameters in Automobile Workers of North Karnataka (India)
    Indian Journal of Clinical Biochemistry, 2011
    Co-Authors: Nilima N. Dongre, Arun J. Patil, Jeevan G Ambekar, Adinath N. Suryakar, Dileep B. Rathi
    Abstract:

    The purpose of this study was to find out the effect of lead exposure on systolic and diastolic blood pressure, heme biosynthesis related and hematological parameters of Automobile Workers. For this study 30 Automobile Workers were selected and compared with 30 age matched healthy control subjects. Significantly increased blood lead (364%, P  

  • biochemical effects of lead exposure on systolic diastolic blood pressure heme biosynthesis and hematological parameters in Automobile Workers of north karnataka india
    Indian Journal of Clinical Biochemistry, 2011
    Co-Authors: Nilima N. Dongre, A. N. Suryakar, Arun J. Patil, Jeevan G Ambekar, Dileep Rathi
    Abstract:

    The purpose of this study was to find out the effect of lead exposure on systolic and diastolic blood pressure, heme biosynthesis related and hematological parameters of Automobile Workers. For this study 30 Automobile Workers were selected and compared with 30 age matched healthy control subjects. Significantly increased blood lead (364%, P < 0.001) and urinary lead (176%, P < 0.001) levels were observed in Automobile Workers (study group) as compared to controls. Systolic blood pressure (5.32%, P < 0.05) and diastolic blood pressure (5.87%, P < 0.05) were significantly increased in the Automobile Workers as compared to controls. The significantly decreased non-activated erythrocyte δ-aminolevulinic acid dehydratase (δ-ALAD) (−18.51%, P < 0.01) and activated δ-ALAD (−13.29%, P < 0.05) levels were observed in Automobile Workers as compared to normal healthy control subjects. But the ratio of activated/non-activated δ-ALAD was significantly increased (43.83%, P < 0.001) in Automobile Workers as compared to controls. Excretions of δ-aminolevulinic acid (83.78%, P < 0.001) and porphobilinogen (37%, P < 0.001) in urine were significantly increased in the study group as compared to the controls. In Automobile Workers heamoglobin (−11.51%, P < 0.001), hematocrit (−4.06%, P < 0.05), mean corpuscle volume (−3.34%, P < 0.05), mean corpuscle hemoglobin (−5.66%, P < 0.01), mean corpuscle hemoglobin concentration (−7.67%, P < 0.001), red blood cell count (−14.6%, P < 0.001) were significantly decreased and total white blood cell count (11.44%, P < 0.05) increased as compared to the controls. The results of this study clearly indicate that the absorption of lead is more in Automobile Workers and it affects on blood pressure, heme biosynthesis and hematological parameters observed in this study group.

  • Occupational lead exposure in Automobile Workers in North Karnataka (India): effect on liver and kidney functions.
    Journal of the Medical Sciences, 2010
    Co-Authors: Nilima N. Dongre, A. N. Suryakar, Arun J. Patil, Dileep B. Rathi
    Abstract:

    We studied liver and kidney function tests of occupational lead exposed Automobile Workers (N = 30), and normal healthy control subjects (N = 30), all 20 to 45 years of age, from Bijapur, North Karnataka (India). Venous blood and random urine samples were collected from both groups. The blood lead [PbB] (364%) and urinary lead [PbU] (176%) levels were significantly increased in Automobile Workers as compared with the controls. Liver function test parameters, i.e. Serum Aspartate Transaminase [AST] (23.88%), Alanine Transaminase [ALT] (24.03%), Alkaline Phosphatase [ALP] (17.99%), Total Bilirubin (45.83%), and Gamma glutamyl Transferase [GGT] (44.75%) were significantly increased in Automobile Workers as compared with the control group. Serum total protein, albumin, globulin, and A/ G ratio were not significantly altered in study group as compared with control subjects. In the kidney function tests levels of blood urea (26%), serum uric acid (13.11%) and serum creatinine (12.5%) were significantly increased in Automobile Workers as compared to control group. Increased PbB values in study group indicate the greater rate of lead absorption and impairment of liver and kidney functions in occupational lead-exposed Automobile Workers from Bijapur, North Karnataka (India).