The Experts below are selected from a list of 324 Experts worldwide ranked by ideXlab platform
Wei Jia - One of the best experts on this subject based on the ideXlab platform.
-
Production of polysialic acid from fed-Batch Fermentation with pH control
Biochemical Engineering Journal, 2002Co-Authors: Xiaobei Zhan, Li Zhu, Zhiyong Zhen, Wei JiaAbstract:Abstract During Batch Fermentation pH affects the production of biomass and polysialic acid in Escherichia coli K235-WXJ4. When the pH of the medium was maintained at 6.4 during the stationary phase, polysialic acid production was prolonged and the specific rate of polysialic acid biosynthesis was higher than when the Fermentation process was not controlled for pH. Controlling the pH during fed-Batch Fermentation of polysialic acid increased the yield of dry cell weight and polysialic acid, which reached 10.16 and 2606 g/l, respectively.
Bonita A. Glatz - One of the best experts on this subject based on the ideXlab platform.
-
Enhanced Bacteriocin Production by Propionibacterium thoenii in Fed-Batch Fermentation ‡.
Journal of food protection, 1997Co-Authors: Hyun-dong Paik, Bonita A. GlatzAbstract:Synthesis of the bacteriocin propionicin PLG-1 as well as culture growth and organic acid production by Propionibacterium thaenii P127 were followed in fed-Batch Fermentations conducted for 504 h in a sodium lactate broth. Average concentrations of viable cells were higher in two small-scale fed-Batch Fermentations than in Batch Fermentations: 2.2 × 109 cells per ml versus 3.7 × 108 cells per ml. Propionic acid concentration averaged 35.8 g/liter at the end of fed-Batch fementation, and maximum bacteriocin titers were 184 and 146 AU/ml in the two fed-Batch Fermentations. After reaching the maximum value, bacteriocin activity dropped sharply upon continued incubation. Large quantities of propionicin PLG-I could be obtained in large-scale fed-Batch Fermentation, but the concentration (100 AU/ml) was lower than in the small-scale Fermentations. Fed-Batch Fermentation shows promise as a method to obtain high concentrations of bacteriocin from the propionibacteria.
-
enhanced bacteriocin production by propionibacterium thoenii in fed Batch Fermentation
Journal of Food Protection, 1997Co-Authors: Hyun-dong Paik, Bonita A. GlatzAbstract:Synthesis of the bacteriocin propionicin PLG-1 as well as culture growth and organic acid production by Propionibacterium thaenii P127 were followed in fed-Batch Fermentations conducted for 504 h in a sodium lactate broth. Average concentrations of viable cells were higher in two small-scale fed-Batch Fermentations than in Batch Fermentations: 2.2 × 109 cells per ml versus 3.7 × 108 cells per ml. Propionic acid concentration averaged 35.8 g/liter at the end of fed-Batch fementation, and maximum bacteriocin titers were 184 and 146 AU/ml in the two fed-Batch Fermentations. After reaching the maximum value, bacteriocin activity dropped sharply upon continued incubation. Large quantities of propionicin PLG-I could be obtained in large-scale fed-Batch Fermentation, but the concentration (100 AU/ml) was lower than in the small-scale Fermentations. Fed-Batch Fermentation shows promise as a method to obtain high concentrations of bacteriocin from the propionibacteria.
P R Goulding - One of the best experts on this subject based on the ideXlab platform.
-
process monitoring of an industrial fed Batch Fermentation
Biotechnology and Bioengineering, 2001Co-Authors: Barry Lennox, H.g. Hiden, G. Kornfeld, G.a. Montague, P R GouldingAbstract:Market demand places great emphasis in in- dustry on product quality. Consequently, process moni- toring and control have become important aspects of systems engineering. In this article we detail the results of a 2-year study focusing on the development of a con- dition monitoring system for a fed-Batch Fermentation system operated by Biochemie Gmbh in Austria. We also demonstrate the suitability and limitations of current state of the art technologies in this field and suggest novel modifications and configurations to improve their suitability for application to a fed-Batch Fermentation sys- tem. © 2001 John Wiley & Sons, Inc. Biotechnol Bioeng 74: 125-135, 2001.
-
Process monitoring of an industrial fed-Batch Fermentation.
Biotechnology and bioengineering, 2001Co-Authors: Barry Lennox, H.g. Hiden, G. Kornfeld, G.a. Montague, P R GouldingAbstract:Market demand places great emphasis in industry on product quality. Consequently, process monitoring and control have become important aspects of systems engineering. In this article we detail the results of a 2-year study focusing on the development of a condition monitoring system for a fed-Batch Fermentation system operated by Biochemie Gmbh in Austria. We also demonstrate the suitability and limitations of current state of the art technologies in this field and suggest novel modifications and configurations to improve their suitability for application to a fed-Batch Fermentation system.
Xiaobei Zhan - One of the best experts on this subject based on the ideXlab platform.
-
Production of polysialic acid from fed-Batch Fermentation with pH control
Biochemical Engineering Journal, 2002Co-Authors: Xiaobei Zhan, Li Zhu, Zhiyong Zhen, Wei JiaAbstract:Abstract During Batch Fermentation pH affects the production of biomass and polysialic acid in Escherichia coli K235-WXJ4. When the pH of the medium was maintained at 6.4 during the stationary phase, polysialic acid production was prolonged and the specific rate of polysialic acid biosynthesis was higher than when the Fermentation process was not controlled for pH. Controlling the pH during fed-Batch Fermentation of polysialic acid increased the yield of dry cell weight and polysialic acid, which reached 10.16 and 2606 g/l, respectively.
Bo Jiang - One of the best experts on this subject based on the ideXlab platform.
-
3 phenyllactic acid production by substrate feeding and ph control in fed Batch Fermentation of lactobacillus sp sk007
Bioresource Technology, 2009Co-Authors: Fengli Liu, Jianghua Jia, Chao Chen, Tao Zhang, Bo JiangAbstract:Abstract 3-Phenyllactic acid (PLA), which is produced by some strains of lactic acid bacteria (LAB), is a known antimicrobial agent with a broad spectrum. Batch and fed-Batch Fermentation by the strain Lactobacillus sp. SK007 for PLA production have been reported. With Batch Fermentation without pH-control, PLA production yield was 2.42 g L −1 . When fed-Batch Fermentation by Lactobacillus sp. SK007 was conducted in 3 L initial volume with pH-control at 6.0 and intermittent feeding, which was developed after Fermentation for 12 h and every 2 h with 120 mL 100 g L −1 PPA phenylpyruvic acid (PPA) and 50 mL 500 g L −1 glucose each time, PLA production yield reached 17.38 g L −1 . The final conversion ratio of PPA to PLA was 51.1%, and the PLA production rate was 0.241 g L −1 h −1 . This indicated that PPA was the ideal substrate for PLA Fermentation production, and fed-Batch Fermentation with intermittent PPA feeding and pH-control was an effective approach to improve PLA production yield.