The Experts below are selected from a list of 3462 Experts worldwide ranked by ideXlab platform
Fritz Duus - One of the best experts on this subject based on the ideXlab platform.
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fast and green microwave assisted conversion of essential oil allylbenzenes into the corresponding aldehydes via alkene isomerization and subsequent potassium permanganate promoted oxidative alkene group cleavage
Molecules, 2009Co-Authors: Thach Ngoc Le, Fritz DuusAbstract:Essential oil allylbenzenes from have been converted quickly and efficiently into the corresponding Benzaldehydes in good yields by a two-step “green” reaction pathway based on a solventless alkene group isomerization by KF/Al2O3 to form the corresponding 1-arylpropene and a subsequent solventless oxidation of the latter to the corresponding benzaldehyde by KMnO4/CuSO4·5H2O. The assistance by microwave irradiation results in very short reaction times (
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fast and green microwave assisted conversion of essential oil allylbenzenes into the corresponding aldehydes via alkene isomerization and subsequent potassium permanganate promoted oxidative alkene group cleavage
Molecules, 2009Co-Authors: Thi Xuan Thi Luu, Trinh To Lam, Fritz DuusAbstract:Essential oil allylbenzenes from have been converted quickly and efficiently into the corresponding Benzaldehydes in good yields by a two-step "green" reaction pathway based on a solventless alkene group isomerization by KF/Al(2)O(3) to form the corresponding 1-arylpropene and a subsequent solventless oxidation of the latter to the corresponding benzaldehyde by KMnO(4)/CuSO(4).5H(2)O. The assistance by microwave irradiation results in very short reaction times (<15 minutes). The green conversion of eugenol (4-allyl-2-methoxyphenol) into vanillin (4-hydroxy-3-methoxybenzaldehyde) has been carried out in a similar way, requiring however two additional microwave-assisted synthetic steps for acetylation of the hydroxy group prior to the oxidation reaction, and for the final deacetylation of vanillin acetate (4-acetoxy-3-methoxybenzaldehyde) by KF/Al(2)O(3) under solvent-free conditions, respectively.
Veronique Michelet - One of the best experts on this subject based on the ideXlab platform.
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silver catalyzed domino hydroarylation cycloisomerization reactions of ortho alkynylBenzaldehydes an entry to functionalized isochromene derivatives
Organic Letters, 2014Co-Authors: Gaelle Mariaule, Gregory John Robert Newsome, Patrick Y Toullec, Philippe Belmont, Veronique MicheletAbstract:A Ag-catalyzed versatile and efficient access to 1H,1-arylisochromenes is reported. Starting from ortho-alkynylBenzaldehydes bearing various substitution patterns on the benzaldehyde and alkynyl units, the use of silver triflate (10 mol %) allowed a domino hydroarylation/cycloisomerization reaction process, leading to aryl-functionalized 1H-isochromene (>10 compounds, 80–98% yields). Notably, the reaction conditions were also compatible with Benzaldehydes bearing an aliphatic-substituted alkynyl moiety with modest to good yields (34–88%, 10 compounds).
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Silver-Catalyzed Domino Hydroarylation/Cycloisomerization Reactions of ortho-AlkynylBenzaldehydes: An Entry to Functionalized Isochromene Derivatives
2014Co-Authors: Gaelle Mariaule, Patrick Y Toullec, Philippe Belmont, Gregory Newsome, Veronique MicheletAbstract:A Ag-catalyzed versatile and efficient access to 1H,1-arylisochromenes is reported. Starting from ortho-alkynylBenzaldehydes bearing various substitution patterns on the benzaldehyde and alkynyl units, the use of silver triflate (10 mol %) allowed a domino hydroarylation/cycloisomerization reaction process, leading to aryl-functionalized 1H-isochromene (>10 compounds, 80–98% yields). Notably, the reaction conditions were also compatible with Benzaldehydes bearing an aliphatic-substituted alkynyl moiety with modest to good yields (34–88%, 10 compounds)
Thi Xuan Thi Luu - One of the best experts on this subject based on the ideXlab platform.
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fast and green microwave assisted conversion of essential oil allylbenzenes into the corresponding aldehydes via alkene isomerization and subsequent potassium permanganate promoted oxidative alkene group cleavage
Molecules, 2009Co-Authors: Thi Xuan Thi Luu, Trinh To Lam, Fritz DuusAbstract:Essential oil allylbenzenes from have been converted quickly and efficiently into the corresponding Benzaldehydes in good yields by a two-step "green" reaction pathway based on a solventless alkene group isomerization by KF/Al(2)O(3) to form the corresponding 1-arylpropene and a subsequent solventless oxidation of the latter to the corresponding benzaldehyde by KMnO(4)/CuSO(4).5H(2)O. The assistance by microwave irradiation results in very short reaction times (<15 minutes). The green conversion of eugenol (4-allyl-2-methoxyphenol) into vanillin (4-hydroxy-3-methoxybenzaldehyde) has been carried out in a similar way, requiring however two additional microwave-assisted synthetic steps for acetylation of the hydroxy group prior to the oxidation reaction, and for the final deacetylation of vanillin acetate (4-acetoxy-3-methoxybenzaldehyde) by KF/Al(2)O(3) under solvent-free conditions, respectively.
Thach Ngoc Le - One of the best experts on this subject based on the ideXlab platform.
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fast and green microwave assisted conversion of essential oil allylbenzenes into the corresponding aldehydes via alkene isomerization and subsequent potassium permanganate promoted oxidative alkene group cleavage
Molecules, 2009Co-Authors: Thach Ngoc Le, Fritz DuusAbstract:Essential oil allylbenzenes from have been converted quickly and efficiently into the corresponding Benzaldehydes in good yields by a two-step “green” reaction pathway based on a solventless alkene group isomerization by KF/Al2O3 to form the corresponding 1-arylpropene and a subsequent solventless oxidation of the latter to the corresponding benzaldehyde by KMnO4/CuSO4·5H2O. The assistance by microwave irradiation results in very short reaction times (
Gaelle Mariaule - One of the best experts on this subject based on the ideXlab platform.
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silver catalyzed domino hydroarylation cycloisomerization reactions of ortho alkynylBenzaldehydes an entry to functionalized isochromene derivatives
Organic Letters, 2014Co-Authors: Gaelle Mariaule, Gregory John Robert Newsome, Patrick Y Toullec, Philippe Belmont, Veronique MicheletAbstract:A Ag-catalyzed versatile and efficient access to 1H,1-arylisochromenes is reported. Starting from ortho-alkynylBenzaldehydes bearing various substitution patterns on the benzaldehyde and alkynyl units, the use of silver triflate (10 mol %) allowed a domino hydroarylation/cycloisomerization reaction process, leading to aryl-functionalized 1H-isochromene (>10 compounds, 80–98% yields). Notably, the reaction conditions were also compatible with Benzaldehydes bearing an aliphatic-substituted alkynyl moiety with modest to good yields (34–88%, 10 compounds).
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Silver-Catalyzed Domino Hydroarylation/Cycloisomerization Reactions of ortho-AlkynylBenzaldehydes: An Entry to Functionalized Isochromene Derivatives
2014Co-Authors: Gaelle Mariaule, Patrick Y Toullec, Philippe Belmont, Gregory Newsome, Veronique MicheletAbstract:A Ag-catalyzed versatile and efficient access to 1H,1-arylisochromenes is reported. Starting from ortho-alkynylBenzaldehydes bearing various substitution patterns on the benzaldehyde and alkynyl units, the use of silver triflate (10 mol %) allowed a domino hydroarylation/cycloisomerization reaction process, leading to aryl-functionalized 1H-isochromene (>10 compounds, 80–98% yields). Notably, the reaction conditions were also compatible with Benzaldehydes bearing an aliphatic-substituted alkynyl moiety with modest to good yields (34–88%, 10 compounds)