The Experts below are selected from a list of 87 Experts worldwide ranked by ideXlab platform
E. H. Mccraw - One of the best experts on this subject based on the ideXlab platform.
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Extractives from the New Zealand myrtaceae. IV.—Triterpene Acids from the bark of Leptospermum ericoides
Journal of the Science of Food and Agriculture, 2006Co-Authors: R. E. Corbett, E. H. MccrawAbstract:Betulic Acid, ursolic Acid, acetate, and a new triterpene Acid, C30H48O4, have been isolated from the outer bark of L. ericoides. Chromatography on silica gel has proved an effective method for the separation of these Acids.
Zhang Qian-qia - One of the best experts on this subject based on the ideXlab platform.
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Isolation and identification of chemical constituents from Ziziphi Spinosae Branch and Folium
Journal of Shenyang Pharmaceutical University, 2020Co-Authors: Zhang Qian-qiaAbstract:Objective To study the chemical constituents from branches and leaves of Z.jujubavar.spinosa.Methods The chemical constituents were isolated and purified by silica gel,polyamide,SephadexLH-20,ODS as well as PR-HPLC and so on.The chemical structures were elucidated on the basis of physic-chemical properties and spectral data.Results Eight compounds were obtained from branches and leaves of Z.jujubavar.spinosa.Their structures were identified as:3-phenyl lactic Acid methyl ester(1),3-(3-indolyl)lactic Acid methyl ester(2),catechin(3),2R,3R-3,5,7,3′,5′-pentahydroxyflavane(4),quercetin-3-O-β-D-glucoside(5),quercetin(6),Betulic Acid(7)and rutin(8).Conclusions Compounds 1-5 are isolated from this genus for the first time.
Huijie Wang - One of the best experts on this subject based on the ideXlab platform.
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study on absorption kinetics of Betulic Acid in rat s intestines
China journal of Chinese materia medica, 2012Co-Authors: Huijun Xu, Yingfeng Du, Lantong Zhang, Tao Li, Ying Ge, Huijie WangAbstract:OBJECTIVE: To establish a HPLC-DAD method for determining concentrations of Betulic Acid and phenol red in intestinal circulation liquid, and probe into the absorption kinetic characteristics of Betulic Acid at different intestine segments in rats and the effect of different drug concentrations on absorption. METHOD: The rat intestinal absorption model was established to detect the impact of absorption site, drug concentration and pH value on drug absorption. RESULT: Within the range from 75-125 mg x L(-1), the absorption rate and the quality concentration of Betulic Acid had a linear relation, with Ka value keeping unchanged. The absorption rate for each intestinal segment showed no remarkable difference, with Ka values in duodenum, jejunum, ileum and colon being (0.151 +/- 0.0049), (0.159 +/- 0.0056), (0.156 +/- 6.0083), (0.149 +/- 0.0041) h(-1), respectively. CONCLUSION: Betulic Acid is proved to be well absorbed in intestines marked by no specific absorption site in the intestine. The absorption mechanism of the drug conforms to passive transport mechanism and first-order kinetics. The bioavailability of Betulic Acid preparation can be increased by enhancing the dissolution rate and the solubility.
Guang-zhong Tu - One of the best experts on this subject based on the ideXlab platform.
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Structure identification of jujuboside E
Yao xue xue bao = Acta pharmaceutica Sinica, 2020Co-Authors: Gong Cheng, Yu-ying Zhao, Bin Wang, Li-bin Ma, Guang-zhong TuAbstract:To study the chemical constituents of the seeds of Ziziphus jujuba Mill var. spinosa (Bunge) Hu ex. H.F. Chou. To separate the constituents by using various kinds of chromatography methods and identify their structures on the basis of spectral analysis. Seven compounds were isolated. Their structures were established as jujuboside E (1), jujuboside B (2), jujuboside A (3), Betulic Acid (4), stearic Acid (5), sucrose (6) and inosine (7). Compound 1 is a new compound named jujuboside E. Compounds 5, 6, 7 were isolated for the first time from this plant.
Li Chun-xue - One of the best experts on this subject based on the ideXlab platform.
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Variation analysis on triterpenoid content in barks of trunk and branch in Betula platyphylla
Nonwood Forest Research, 2020Co-Authors: Li Chun-xueAbstract:To find out Betula platyphylla family with high triterpenoid content,taking 11 families in B.platyphylla from Xiaobeihu as materials,variation status of the triterpenoid content in different parts and families was analyzed by high performance liquid chromatography(HPLC).The results show that the kinds and contents of triterpenoid in barks of trunk and branch are different,the triterpenoid content in bark is higher than that in bark of branch,and Betulic Acid detected in bark is not found in bark of branch.In addition,based on tree height and diameter at breast height,Among of the families with higher growth rate,No.2,No.3,No.5 and No.10 families have higher triterpenoid accumulation in the bark of trunk,and No.2 and No.5 families have higher triterpenoid accumulation in the bark of branch.Thus the parts and family of tree have effect on the kind and content of triterpenoid.
