The Experts below are selected from a list of 318 Experts worldwide ranked by ideXlab platform
Guihua Huang - One of the best experts on this subject based on the ideXlab platform.
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Recent developments of biodegradable and Biocompatible Materials based micro/nanoparticles for delivering macromolecular therapeutics.
Critical reviews in therapeutic drug carrier systems, 2009Co-Authors: Yang Shi, Guihua HuangAbstract:Developments in biotechnology have seen the growing use of macromolecules containing proteins, peptides, vaccines, antigens, genes, and growth factors as therapeutic agents. Because these macromolecules are easily denatured and metabolized rapidly in vivo, their protection and controlled release are required. Biodegradable and Biocompatible Materials based micro/nanoparticles (MPs/NPs) show great potential for delivering macromolecular therapeutics. One of the greatest challenges in the delivery of macromolecules from biodegradable and Biocompatible MPs/NPs is the controlled and complete release of the drugs in their native forms. Unfortunately, the present drug delivery systems cannot satisfy the requirement; thus, more research is expected. This article discusses the recent developments in the field of macromolecular delivery.
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recent developments of biodegradable and Biocompatible Materials based micro nanoparticles for delivering macromolecular therapeutics
Critical Reviews in Therapeutic Drug Carrier Systems, 2009Co-Authors: Yang Shi, Guihua HuangAbstract:Developments in biotechnology have seen the growing use of macromolecules containing proteins, peptides, vaccines, antigens, genes, and growth factors as therapeutic agents. Because these macromolecules are easily denatured and metabolized rapidly in vivo, their protection and controlled release are required. Biodegradable and Biocompatible Materials based micro/nanoparticles (MPs/NPs) show great potential for delivering macromolecular therapeutics. One of the greatest challenges in the delivery of macromolecules from biodegradable and Biocompatible MPs/NPs is the controlled and complete release of the drugs in their native forms. Unfortunately, the present drug delivery systems cannot satisfy the requirement; thus, more research is expected. This article discusses the recent developments in the field of macromolecular delivery.
Xin Su - One of the best experts on this subject based on the ideXlab platform.
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hydrophilic hydrophobic heterogeneity anti biofouling hydrogels with well regulated rehydration
ACS Applied Materials & Interfaces, 2020Co-Authors: Xin Su, Xiuqi Xu, Zhengning LiAbstract:Hydrogels, as a representative of soft and Biocompatible Materials, have been widely used in biosensors, biomedical devices, soft robotics, and the marine industry. However, the ir-recoverability o...
Yukio Imanishi - One of the best experts on this subject based on the ideXlab platform.
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synthesis and evaluation of heparinized Biocompatible Materials using heparin surface active compound complexes
Journal of Bioactive and Compatible Polymers, 1993Co-Authors: Takashi Kashiwagi, Yoshihiro Ito, Yukio ImanishiAbstract:Heparin, an antithrombogenic mucopolysaccharide, forms com plexes with lecithin and other surface-active compounds (SAC). The complexes are soluble in organic solvents. The heparin/SAC complexes have antithrombo genic activity similar to heparin. Heparinized Materials, in which the heparin/SAC complexes were used, showed an excellent in vitro nonthrombo genicity. The heparinized Materials do not influence in vitro cell growth and showed an excellent biocompatibility.
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Synthesis and Evaluation of Heparinized Biocompatible Materials Using Heparin/Surface-Active Compound Complexes
Journal of Bioactive and Compatible Polymers, 1993Co-Authors: Takashi Kashiwagi, Yoshihiro Ito, Yukio ImanishiAbstract:Heparin, an antithrombogenic mucopolysaccharide, forms com plexes with lecithin and other surface-active compounds (SAC). The complexes are soluble in organic solvents. The heparin/SAC complexes have antithrombo genic activity similar to heparin. Heparinized Materials, in which the heparin/SAC complexes were used, showed an excellent in vitro nonthrombo genicity. The heparinized Materials do not influence in vitro cell growth and showed an excellent biocompatibility.
Zhengning Li - One of the best experts on this subject based on the ideXlab platform.
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hydrophilic hydrophobic heterogeneity anti biofouling hydrogels with well regulated rehydration
ACS Applied Materials & Interfaces, 2020Co-Authors: Xin Su, Xiuqi Xu, Zhengning LiAbstract:Hydrogels, as a representative of soft and Biocompatible Materials, have been widely used in biosensors, biomedical devices, soft robotics, and the marine industry. However, the ir-recoverability o...
Yang Shi - One of the best experts on this subject based on the ideXlab platform.
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Recent developments of biodegradable and Biocompatible Materials based micro/nanoparticles for delivering macromolecular therapeutics.
Critical reviews in therapeutic drug carrier systems, 2009Co-Authors: Yang Shi, Guihua HuangAbstract:Developments in biotechnology have seen the growing use of macromolecules containing proteins, peptides, vaccines, antigens, genes, and growth factors as therapeutic agents. Because these macromolecules are easily denatured and metabolized rapidly in vivo, their protection and controlled release are required. Biodegradable and Biocompatible Materials based micro/nanoparticles (MPs/NPs) show great potential for delivering macromolecular therapeutics. One of the greatest challenges in the delivery of macromolecules from biodegradable and Biocompatible MPs/NPs is the controlled and complete release of the drugs in their native forms. Unfortunately, the present drug delivery systems cannot satisfy the requirement; thus, more research is expected. This article discusses the recent developments in the field of macromolecular delivery.
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recent developments of biodegradable and Biocompatible Materials based micro nanoparticles for delivering macromolecular therapeutics
Critical Reviews in Therapeutic Drug Carrier Systems, 2009Co-Authors: Yang Shi, Guihua HuangAbstract:Developments in biotechnology have seen the growing use of macromolecules containing proteins, peptides, vaccines, antigens, genes, and growth factors as therapeutic agents. Because these macromolecules are easily denatured and metabolized rapidly in vivo, their protection and controlled release are required. Biodegradable and Biocompatible Materials based micro/nanoparticles (MPs/NPs) show great potential for delivering macromolecular therapeutics. One of the greatest challenges in the delivery of macromolecules from biodegradable and Biocompatible MPs/NPs is the controlled and complete release of the drugs in their native forms. Unfortunately, the present drug delivery systems cannot satisfy the requirement; thus, more research is expected. This article discusses the recent developments in the field of macromolecular delivery.