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Biomedical Application

The Experts below are selected from a list of 126819 Experts worldwide ranked by ideXlab platform

Erlin Zhang – 1st expert on this subject based on the ideXlab platform

  • the antibacterial properties and biocompatibility of a ti cu sintered alloy for Biomedical Application
    Biomedical Materials, 2014
    Co-Authors: Xinxin Zhang, Erlin Zhang, Ke Yang, Hongying Wang, Fangbing Li, Muqin Li

    Abstract:

    The antibacterial activity, the cytotoxicity and the cell function of a sintered Ti-10?wt% Cu alloy were investigated in order to assess the suitability of the alloy for Biomedical Application. The antibacterial activity of the alloy was investigated by a plate-count method and the cytotoxicity was studied by examining the MG63 cell response by CCK8 assessment. The cell function was monitored by measuring the AKP activity. The Cu ion released from the Ti?Cu alloy was also measured by an inductively coupled plasma spectrometer at different immersion durations. The results show that the antibacterial rates of the alloy against Escherichia coli and Staphylococcus aureus increase with an increase in the incubation duration. After 7?h of incubation, the alloy showed an antibacterial rate of 91.66% against S. aureus and 99. 01% against E. coli. With a further extension of incubation time to 24?h, the antibacterial rate increased to 100% against S. aureus and 99.93% against E. coli. No cytotoxicity was observed on the alloy by a CKK8 test during three days of incubation in comparison with commercially available pure titanium (cp-Ti). AKP test results showed a significantly high AKP value (p = 0.001 < 0.01) on the Ti?Cu alloy on day 1. The Cu ion release was thought to contribute to the strong antibacterial property, but the Cu ion did not lead to cell cytotoxicity. Strong antibacterial activity and good cell biocompatibility suggest that the Ti?Cu alloy could reduce bacterial infection and have a potential Application as an implant material.

  • microstructure corrosion properties and bio compatibility of calcium zinc phosphate coating on pure iron for Biomedical Application
    Materials Science and Engineering: C, 2014
    Co-Authors: Haiyan Chen, Erlin Zhang, Ke Yang

    Abstract:

    Abstract In order to improve the biocompatibility and the corrosion resistance in the initial stage of implantation, a phosphate (CaZn2(PO4)2 · 2H2O) coating was obtained on the surface of pure iron by a chemical reaction method. The anti-corrosion property, the blood compatibility and the cell toxicity of the coated pure iron specimens were investigated. The coating was composed of some fine phosphate crystals and the surface of coating was flat and dense enough. The electrochemical data indicated that the corrosion resistance of the coated pure iron was improved with the increase of phosphating time. When the specimen was phosphated for 30 min, the corrosion resistance (Rp) increased to 8006 Ω. Compared with that of the naked pure iron, the anti-hemolysis property and cell compatibility of the coated specimen was improved significantly, while the anti-coagulant property became slightly worse due to the existence of element calcium. It was thought that phosphating treatment might be an effective method to improve the biocompatibility of pure iron for Biomedical Application.

  • effects of zn on the microstructure mechanical property and bio corrosion property of mg 3ca alloys for Biomedical Application
    Materials Chemistry and Physics, 2011
    Co-Authors: Hui Du, Erlin Zhang

    Abstract:

    Abstract The effects of the addition of Zn element on the microstructures, mechanical properties and bio-corrosion properties of Mg–3Ca alloys are investigated. The microstructure and X-ray diffraction topography indicate that as-cast Mg–3Ca alloys are composed of primary Mg and eutectic (α-Mg + Mg2Ca) phases, while Mg–3Ca–2Zn alloys are constituted of primary Mg and eutectic (α-Mg + Mg2Ca + Ca2Mg6Zn3) phases. Mechanical properties results show that the element Zn could improve both tensile strength and elongation of Mg–3Ca alloys. The ultimate tensile strength is enhanced by 22%. Meanwhile, the corrosion resistance is increased by the addition of Zn element. It is thought that the presence of Ca2Mg6Zn3 phase mainly contributes to these improvements. Mg–3Ca–2Zn alloy provides moderate strength and excellent corrosion resistance for Biomedical Application.

Xiabin Jing – 2nd expert on this subject based on the ideXlab platform

  • biodegradable synthetic polymers preparation functionalization and Biomedical Application
    Progress in Polymer Science, 2012
    Co-Authors: Huayu Tian, Zhaohui Tang, Xiuli Zhuang, Xuesi Chen, Xiabin Jing

    Abstract:

    Abstract Biodegradable polymers have been widely used and have greatly promoted the development of Biomedical fields because of their biocompatibility and biodegradability. The development of biotechnology and medical technology has set higher requirements for Biomedical materials. Novel biodegradable polymers with specific properties are in great demand. Biodegradable polymers can be classified as natural or synthetic polymers according to the source. Synthetic biodegradable polymers have found more versatile and diverse Biomedical Applications owing to their tailorable designs or modifications. This review presents a comprehensive introduction to various types of synthetic biodegradable polymers with reactive groups and bioactive groups, and further describes their structure, preparation procedures and properties. The focus is on advances in the past decade in functionalization and responsive strategies of biodegradable polymers and their Biomedical Applications. The possible future developments of the materials are also discussed.

  • Biodegradable synthetic polymers: Preparation, functionalization and Biomedical Application
    Progress in Polymer Science (Oxford), 2012
    Co-Authors: Huayu Tian, Zhaohui Tang, Xiuli Zhuang, Xuesi Chen, Xiabin Jing

    Abstract:

    Biodegradable polymers have been widely used and have greatly promoted the development of Biomedical fields because of their biocompatibility and biodegradability. The development of biotechnology and medical technology has set higher requirements for Biomedical materials. Novel biodegradable polymers with specific properties are in great demand. Biodegradable polymers can be classified as natural or synthetic polymers according to the source. Synthetic biodegradable polymers have found more versatile and diverse Biomedical Applications owing to their tailorable designs or modifications. This review presents a comprehensive introduction to various types of synthetic biodegradable polymers with reactive groups and bioactive groups, and further describes their structure, preparation procedures and properties. The focus is on advances in the past decade in functionalization and responsive strategies of biodegradable polymers and their Biomedical Applications. The possible future developments of the materials are also discussed. © 2011 Elsevier Ltd. All rights reserved.

Huayu Tian – 3rd expert on this subject based on the ideXlab platform

  • biodegradable synthetic polymers preparation functionalization and Biomedical Application
    Progress in Polymer Science, 2012
    Co-Authors: Huayu Tian, Zhaohui Tang, Xiuli Zhuang, Xuesi Chen, Xiabin Jing

    Abstract:

    Abstract Biodegradable polymers have been widely used and have greatly promoted the development of Biomedical fields because of their biocompatibility and biodegradability. The development of biotechnology and medical technology has set higher requirements for Biomedical materials. Novel biodegradable polymers with specific properties are in great demand. Biodegradable polymers can be classified as natural or synthetic polymers according to the source. Synthetic biodegradable polymers have found more versatile and diverse Biomedical Applications owing to their tailorable designs or modifications. This review presents a comprehensive introduction to various types of synthetic biodegradable polymers with reactive groups and bioactive groups, and further describes their structure, preparation procedures and properties. The focus is on advances in the past decade in functionalization and responsive strategies of biodegradable polymers and their Biomedical Applications. The possible future developments of the materials are also discussed.

  • Biodegradable synthetic polymers: Preparation, functionalization and Biomedical Application
    Progress in Polymer Science (Oxford), 2012
    Co-Authors: Huayu Tian, Zhaohui Tang, Xiuli Zhuang, Xuesi Chen, Xiabin Jing

    Abstract:

    Biodegradable polymers have been widely used and have greatly promoted the development of Biomedical fields because of their biocompatibility and biodegradability. The development of biotechnology and medical technology has set higher requirements for Biomedical materials. Novel biodegradable polymers with specific properties are in great demand. Biodegradable polymers can be classified as natural or synthetic polymers according to the source. Synthetic biodegradable polymers have found more versatile and diverse Biomedical Applications owing to their tailorable designs or modifications. This review presents a comprehensive introduction to various types of synthetic biodegradable polymers with reactive groups and bioactive groups, and further describes their structure, preparation procedures and properties. The focus is on advances in the past decade in functionalization and responsive strategies of biodegradable polymers and their Biomedical Applications. The possible future developments of the materials are also discussed. © 2011 Elsevier Ltd. All rights reserved.