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Ite Lee - One of the best experts on this subject based on the ideXlab platform.

  • combined extractives of red yeast rice Bitter Gourd chlorella soy protein and licorice improve total cholesterol low density lipoprotein cholesterol and triglyceride in subjects with metabolic syndrome
    Nutrition Research, 2012
    Co-Authors: Ite Lee, Wenjane Lee, Chingmin Tsai, Hsientung Yen, Wayne Hh Sheu
    Abstract:

    Abstract In this study, we aimed to examine the effects of a plant-extractive compound on lipid profiles in subjects with metabolic syndrome. We hypothesized that extractives from red yeast rice, Bitter Gourd, chlorella, soy protein, and licorice have synergistic benefits on cholesterol and metabolic syndrome. In this double-blinded study, adult subjects with metabolic syndrome were randomized to receive a plant-extractive compound or a placebo treatment for 12 weeks. Both total cholesterol (5.4 ± 0.8 to 4.4 ± 0.6 mmol/L, P P P P P = .039). There was also a significantly greater reduction in the proportion of subjects with hypertensive criteria in the plant-extractive group than in the placebo group ( P = .040). In conclusion, the plant extractives from red yeast rice, Bitter Gourd, chlorella, soy protein, and licorice were effective in reducing total and low-density lipoprotein cholesterol. The plant extractives also showed potential for reducing triglyceride and normalizing blood pressure.

  • combined extractives of red yeast rice Bitter Gourd chlorella soy protein and licorice improve total cholesterol low density lipoprotein cholesterol and triglyceride in subjects with metabolic syndrome
    Nutrition Research, 2012
    Co-Authors: Ite Lee, Wenjane Lee, Chingmin Tsai, Hsientung Yen, Wayne Hh Sheu
    Abstract:

    In this study, we aimed to examine the effects of a plant-extractive compound on lipid profiles in subjects with metabolic syndrome. We hypothesized that extractives from red yeast rice, Bitter Gourd, chlorella, soy protein, and licorice have synergistic benefits on cholesterol and metabolic syndrome. In this double-blinded study, adult subjects with metabolic syndrome were randomized to receive a plant-extractive compound or a placebo treatment for 12 weeks. Both total cholesterol (5.4 ± 0.8 to 4.4 ± 0.6 mmol/L, P < .001) and low-density lipoprotein cholesterol (3.4 ± 0.7 to 2.7 ± 0.5 mmol/L, P < .001) were significantly reduced after treatment with the plant extractives, and the magnitudes of reduction were significantly greater than in the placebo group (-1.0 ± 0.6 vs 0.0 ± 0.6mmol/L, P < .001; -0.7 ± 0.6 vs 0.0 ± 0.6 mmol/L, P < .001). The reduction in the fasting triglycerides level was significantly greater in the plant-extractive group than in the placebo group (-0.5 ± 0.8 vs -0.2 ± 1.0 mmol/L, P = .039). There was also a significantly greater reduction in the proportion of subjects with hypertensive criteria in the plant-extractive group than in the placebo group (P = .040). In conclusion, the plant extractives from red yeast rice, Bitter Gourd, chlorella, soy protein, and licorice were effective in reducing total and low-density lipoprotein cholesterol. The plant extractives also showed potential for reducing triglyceride and normalizing blood pressure.

Wayne Hh Sheu - One of the best experts on this subject based on the ideXlab platform.

  • combined extractives of red yeast rice Bitter Gourd chlorella soy protein and licorice improve total cholesterol low density lipoprotein cholesterol and triglyceride in subjects with metabolic syndrome
    Nutrition Research, 2012
    Co-Authors: Ite Lee, Wenjane Lee, Chingmin Tsai, Hsientung Yen, Wayne Hh Sheu
    Abstract:

    Abstract In this study, we aimed to examine the effects of a plant-extractive compound on lipid profiles in subjects with metabolic syndrome. We hypothesized that extractives from red yeast rice, Bitter Gourd, chlorella, soy protein, and licorice have synergistic benefits on cholesterol and metabolic syndrome. In this double-blinded study, adult subjects with metabolic syndrome were randomized to receive a plant-extractive compound or a placebo treatment for 12 weeks. Both total cholesterol (5.4 ± 0.8 to 4.4 ± 0.6 mmol/L, P P P P P = .039). There was also a significantly greater reduction in the proportion of subjects with hypertensive criteria in the plant-extractive group than in the placebo group ( P = .040). In conclusion, the plant extractives from red yeast rice, Bitter Gourd, chlorella, soy protein, and licorice were effective in reducing total and low-density lipoprotein cholesterol. The plant extractives also showed potential for reducing triglyceride and normalizing blood pressure.

  • combined extractives of red yeast rice Bitter Gourd chlorella soy protein and licorice improve total cholesterol low density lipoprotein cholesterol and triglyceride in subjects with metabolic syndrome
    Nutrition Research, 2012
    Co-Authors: Ite Lee, Wenjane Lee, Chingmin Tsai, Hsientung Yen, Wayne Hh Sheu
    Abstract:

    In this study, we aimed to examine the effects of a plant-extractive compound on lipid profiles in subjects with metabolic syndrome. We hypothesized that extractives from red yeast rice, Bitter Gourd, chlorella, soy protein, and licorice have synergistic benefits on cholesterol and metabolic syndrome. In this double-blinded study, adult subjects with metabolic syndrome were randomized to receive a plant-extractive compound or a placebo treatment for 12 weeks. Both total cholesterol (5.4 ± 0.8 to 4.4 ± 0.6 mmol/L, P < .001) and low-density lipoprotein cholesterol (3.4 ± 0.7 to 2.7 ± 0.5 mmol/L, P < .001) were significantly reduced after treatment with the plant extractives, and the magnitudes of reduction were significantly greater than in the placebo group (-1.0 ± 0.6 vs 0.0 ± 0.6mmol/L, P < .001; -0.7 ± 0.6 vs 0.0 ± 0.6 mmol/L, P < .001). The reduction in the fasting triglycerides level was significantly greater in the plant-extractive group than in the placebo group (-0.5 ± 0.8 vs -0.2 ± 1.0 mmol/L, P = .039). There was also a significantly greater reduction in the proportion of subjects with hypertensive criteria in the plant-extractive group than in the placebo group (P = .040). In conclusion, the plant extractives from red yeast rice, Bitter Gourd, chlorella, soy protein, and licorice were effective in reducing total and low-density lipoprotein cholesterol. The plant extractives also showed potential for reducing triglyceride and normalizing blood pressure.

Qayyum Husain - One of the best experts on this subject based on the ideXlab platform.

  • calcium alginate starch hybrid support for both surface immobilization and entrapment of Bitter Gourd momordica charantia peroxidase
    Journal of Molecular Catalysis B-enzymatic, 2009
    Co-Authors: Mahreen Matto, Qayyum Husain
    Abstract:

    Abstract Calcium alginate–starch hybrid gel was employed as an enzyme carrier both for surface immobilization and entrapment of Bitter Gourd peroxidase. Entrapped crosslinked concanavalin A–Bitter Gourd peroxidase retained 52% of the initial activity while surface immobilized and glutaraldehyde crosslinked enzyme showed 63% activity. A comparative stability of both forms of immobilized Bitter Gourd peroxidase was investigated against pH, temperature and chaotropic agent; like urea, heavy metals, water-miscible organic solvents, detergent and inhibitors. Entrapped peroxidase was significantly more stable as compared to surface immobilized form of enzyme. The pH and temperature-optima for both immobilized preparations were the same as for soluble Bitter Gourd peroxidase. Entrapped crosslinked concanavalin A–Bitter Gourd peroxidase showed 75% of the initial activity while the surface immobilized and crosslinked Bitter Gourd peroxidase retained 69% of the original activity after its seventh repeated use.

  • potential applications of immobilized Bitter Gourd momordica charantia peroxidase in the removal of phenols from polluted water
    Chemosphere, 2006
    Co-Authors: Suhail Akhtar, Qayyum Husain
    Abstract:

    Abstract The potential applications of immobilized Bitter Gourd peroxidase in the treatment of model wastewater contaminated with phenols have been investigated. The synthetic water was treated with soluble and immobilized enzyme preparations under various experimental conditions. Maximum removal of phenols was found in the buffers of pH values 5.0–6.0 and at 40 °C in the presence of 0.75 mM H 2 O 2 . Fourteen different phenols were independently treated with soluble and immobilized Bitter Gourd peroxidase in the buffer of pH 5.6 at 37 °C. Chlorinated phenols and native phenol were significantly removed while other substituted phenols were marginally removed by the treatment. Phloroglucinol and pyrogallol were recalcitrant to the action of Bitter Gourd peroxidase. Immobilized Bitter Gourd peroxidase preparation was capable of removing remarkably high percentage of phenols from the phenolic mixtures. Significantly higher level of total organic carbon was removed from the model wastewater containing individual phenol or complex mixture of phenols by immobilized Bitter Gourd peroxidase as compared to the soluble enzyme. 2,4-dichlorophenol and a phenolic mixture were also treated in a stirred batch reactor with fixed quantity of enzyme for longer duration. The soluble Bitter Gourd peroxidase ceased to function after 3 h while the immobilized enzyme was active even after 6 h of incubation with phenolic solutions.

  • direct immobilization of peroxidase on deae cellulose from ammonium sulphate fractionated proteins of Bitter Gourd momordica charantia
    Enzyme and Microbial Technology, 2006
    Co-Authors: Yasha Kulshrestha, Qayyum Husain
    Abstract:

    Abstract The direct immobilization of peroxidases on DEAE cellulose from ammonium sulphate fractionated proteins of Bitter Gourd has been investigated. The activated DEAE cellulose was quite effective in high yield immobilization of peroxidases from Bitter Gourd and it could bind nearly 590 enzyme units per g of the matrix. Bitter Gourd peroxidase immobilized on this anion exchanger showed very high effectiveness factor ‘ η ’ as 0.95. BGP bound very strongly to the DEAE cellulose, as it did not detach even in the presence of 0.5 M NaCl. Immobilized Bitter Gourd peroxidase preparation was more stable to the denaturation induced by pH, heat, urea, proteolytic enzyme, detergents (Surf Excel and Rin powder), Triton X 100 and water-miscible organic solvents (dioxane, dimethyl sulphoxide and n -propanol). Peroxidase adsorbed on the matrix exhibited very high resistance to proteolysis mediated by the trypsin treatment. DEAE cellulose bound Bitter Gourd peroxidase lost 45% of its initial activity after treatment with 2.5 mg trypsin per ml of incubation mixture for 1 h at 37 °C while the soluble enzyme lost nearly 65% of the initial activity under similar incubation conditions.

  • potential of immobilized Bitter Gourd momordica charantia peroxidases in the decolorization and removal of textile dyes from polluted wastewater and dyeing effluent
    Chemosphere, 2005
    Co-Authors: Suhail Akhtar, Amjad Ali Khan, Qayyum Husain
    Abstract:

    Abstract Immobilized peroxidases from Momordica charantia were highly effective in decolorizing reactive textile dyes compared to its soluble counterpart. Dye solutions, 50–200 mg/l, were treated with soluble and immobilized Bitter Gourd peroxidases (specific activity of 99.0 EU per mg protein). The decolorization of dyes with soluble and immobilized enzyme was maximum in the range of pH 3.0–4.0. The effect of different temperatures on the dye decolorization was monitored and it was observed that all the dyes were maximally decolorized at 40 °C. In order to examine the operational stability of the immobilized preparation, the enzyme was repeatedly exploited for the decolorization of the dyes from fresh batch of dye solutions. Even after 10 cycles in each case the immobilized preparation retained nearly 50% of the initial enzyme activity. The immobilized enzyme exhibited more than 90% of the original activity while the soluble enzyme lost 33% of the initial activity when stored for 40 d at room temperature. Mixtures of three, four and eight dyes were prepared and treated with soluble and immobilized Bitter Gourd peroxidase. Each mixture was decolorized by more than 80% when treated with immobilized enzyme. Dyeing effluent collected from local dyers was treated with both types of enzyme preparations. Immobilized enzyme was capable of removing remarkably high concentration of color from the effluent. TOC content of soluble and immobilized enzyme treated individual dyes, mixture of dyes and dyeing effluent was determined and it was observed that higher TOC was removed after treatment with immobilized enzyme.

  • potential of immobilized Bitter Gourd momordica charantia peroxidases in the decolorization and removal of textile dyes from polluted wastewater and dyeing effluent
    Chemosphere, 2005
    Co-Authors: Suhail Akhtar, Amjad Ali Khan, Qayyum Husain
    Abstract:

    Immobilized peroxidases from Momordica charantia were highly effective in decolorizing reactive textile dyes compared to its soluble counterpart. Dye solutions, 50-200 mg/l, were treated with soluble and immobilized Bitter Gourd peroxidases (specific activity of 99.0 EU per mg protein). The decolorization of dyes with soluble and immobilized enzyme was maximum in the range of pH 3.0-4.0. The effect of different temperatures on the dye decolorization was monitored and it was observed that all the dyes were maximally decolorized at 40 degrees C. In order to examine the operational stability of the immobilized preparation, the enzyme was repeatedly exploited for the decolorization of the dyes from fresh batch of dye solutions. Even after 10 cycles in each case the immobilized preparation retained nearly 50% of the initial enzyme activity. The immobilized enzyme exhibited more than 90% of the original activity while the soluble enzyme lost 33% of the initial activity when stored for 40 d at room temperature. Mixtures of three, four and eight dyes were prepared and treated with soluble and immobilized Bitter Gourd peroxidase. Each mixture was decolorized by more than 80% when treated with immobilized enzyme. Dyeing effluent collected from local dyers was treated with both types of enzyme preparations. Immobilized enzyme was capable of removing remarkably high concentration of color from the effluent. TOC content of soluble and immobilized enzyme treated individual dyes, mixture of dyes and dyeing effluent was determined and it was observed that higher TOC was removed after treatment with immobilized enzyme.

Hsientung Yen - One of the best experts on this subject based on the ideXlab platform.

  • combined extractives of red yeast rice Bitter Gourd chlorella soy protein and licorice improve total cholesterol low density lipoprotein cholesterol and triglyceride in subjects with metabolic syndrome
    Nutrition Research, 2012
    Co-Authors: Ite Lee, Wenjane Lee, Chingmin Tsai, Hsientung Yen, Wayne Hh Sheu
    Abstract:

    Abstract In this study, we aimed to examine the effects of a plant-extractive compound on lipid profiles in subjects with metabolic syndrome. We hypothesized that extractives from red yeast rice, Bitter Gourd, chlorella, soy protein, and licorice have synergistic benefits on cholesterol and metabolic syndrome. In this double-blinded study, adult subjects with metabolic syndrome were randomized to receive a plant-extractive compound or a placebo treatment for 12 weeks. Both total cholesterol (5.4 ± 0.8 to 4.4 ± 0.6 mmol/L, P P P P P = .039). There was also a significantly greater reduction in the proportion of subjects with hypertensive criteria in the plant-extractive group than in the placebo group ( P = .040). In conclusion, the plant extractives from red yeast rice, Bitter Gourd, chlorella, soy protein, and licorice were effective in reducing total and low-density lipoprotein cholesterol. The plant extractives also showed potential for reducing triglyceride and normalizing blood pressure.

  • combined extractives of red yeast rice Bitter Gourd chlorella soy protein and licorice improve total cholesterol low density lipoprotein cholesterol and triglyceride in subjects with metabolic syndrome
    Nutrition Research, 2012
    Co-Authors: Ite Lee, Wenjane Lee, Chingmin Tsai, Hsientung Yen, Wayne Hh Sheu
    Abstract:

    In this study, we aimed to examine the effects of a plant-extractive compound on lipid profiles in subjects with metabolic syndrome. We hypothesized that extractives from red yeast rice, Bitter Gourd, chlorella, soy protein, and licorice have synergistic benefits on cholesterol and metabolic syndrome. In this double-blinded study, adult subjects with metabolic syndrome were randomized to receive a plant-extractive compound or a placebo treatment for 12 weeks. Both total cholesterol (5.4 ± 0.8 to 4.4 ± 0.6 mmol/L, P < .001) and low-density lipoprotein cholesterol (3.4 ± 0.7 to 2.7 ± 0.5 mmol/L, P < .001) were significantly reduced after treatment with the plant extractives, and the magnitudes of reduction were significantly greater than in the placebo group (-1.0 ± 0.6 vs 0.0 ± 0.6mmol/L, P < .001; -0.7 ± 0.6 vs 0.0 ± 0.6 mmol/L, P < .001). The reduction in the fasting triglycerides level was significantly greater in the plant-extractive group than in the placebo group (-0.5 ± 0.8 vs -0.2 ± 1.0 mmol/L, P = .039). There was also a significantly greater reduction in the proportion of subjects with hypertensive criteria in the plant-extractive group than in the placebo group (P = .040). In conclusion, the plant extractives from red yeast rice, Bitter Gourd, chlorella, soy protein, and licorice were effective in reducing total and low-density lipoprotein cholesterol. The plant extractives also showed potential for reducing triglyceride and normalizing blood pressure.

Chingmin Tsai - One of the best experts on this subject based on the ideXlab platform.

  • combined extractives of red yeast rice Bitter Gourd chlorella soy protein and licorice improve total cholesterol low density lipoprotein cholesterol and triglyceride in subjects with metabolic syndrome
    Nutrition Research, 2012
    Co-Authors: Ite Lee, Wenjane Lee, Chingmin Tsai, Hsientung Yen, Wayne Hh Sheu
    Abstract:

    Abstract In this study, we aimed to examine the effects of a plant-extractive compound on lipid profiles in subjects with metabolic syndrome. We hypothesized that extractives from red yeast rice, Bitter Gourd, chlorella, soy protein, and licorice have synergistic benefits on cholesterol and metabolic syndrome. In this double-blinded study, adult subjects with metabolic syndrome were randomized to receive a plant-extractive compound or a placebo treatment for 12 weeks. Both total cholesterol (5.4 ± 0.8 to 4.4 ± 0.6 mmol/L, P P P P P = .039). There was also a significantly greater reduction in the proportion of subjects with hypertensive criteria in the plant-extractive group than in the placebo group ( P = .040). In conclusion, the plant extractives from red yeast rice, Bitter Gourd, chlorella, soy protein, and licorice were effective in reducing total and low-density lipoprotein cholesterol. The plant extractives also showed potential for reducing triglyceride and normalizing blood pressure.

  • combined extractives of red yeast rice Bitter Gourd chlorella soy protein and licorice improve total cholesterol low density lipoprotein cholesterol and triglyceride in subjects with metabolic syndrome
    Nutrition Research, 2012
    Co-Authors: Ite Lee, Wenjane Lee, Chingmin Tsai, Hsientung Yen, Wayne Hh Sheu
    Abstract:

    In this study, we aimed to examine the effects of a plant-extractive compound on lipid profiles in subjects with metabolic syndrome. We hypothesized that extractives from red yeast rice, Bitter Gourd, chlorella, soy protein, and licorice have synergistic benefits on cholesterol and metabolic syndrome. In this double-blinded study, adult subjects with metabolic syndrome were randomized to receive a plant-extractive compound or a placebo treatment for 12 weeks. Both total cholesterol (5.4 ± 0.8 to 4.4 ± 0.6 mmol/L, P < .001) and low-density lipoprotein cholesterol (3.4 ± 0.7 to 2.7 ± 0.5 mmol/L, P < .001) were significantly reduced after treatment with the plant extractives, and the magnitudes of reduction were significantly greater than in the placebo group (-1.0 ± 0.6 vs 0.0 ± 0.6mmol/L, P < .001; -0.7 ± 0.6 vs 0.0 ± 0.6 mmol/L, P < .001). The reduction in the fasting triglycerides level was significantly greater in the plant-extractive group than in the placebo group (-0.5 ± 0.8 vs -0.2 ± 1.0 mmol/L, P = .039). There was also a significantly greater reduction in the proportion of subjects with hypertensive criteria in the plant-extractive group than in the placebo group (P = .040). In conclusion, the plant extractives from red yeast rice, Bitter Gourd, chlorella, soy protein, and licorice were effective in reducing total and low-density lipoprotein cholesterol. The plant extractives also showed potential for reducing triglyceride and normalizing blood pressure.